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Select item 61108531.

NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy

Alexandre Dubrac, Steffen E. Künzel, Sandrine H. Künzel, Jinyu Li, Rachana Radhamani Chandran, Kathleen Martin, Daniel M. Greif, Ralf H. Adams, Anne Eichmann

Nat Commun. 2018; 9: 3463. Published online 2018 Aug 27. doi: 10.1038/s41467-018-05926-7

PMCID:: PMC6110853

Abstract Article PDF–9.4M

Select item 54777212.

Nck2, an unexpected regulator of adipogenesis

N. Haider, J. Dusseault, A. Rudich, L. Larose

Adipocyte. 2017; 6(2): 154–160. Published online 2017 Feb 6. doi: 10.1080/21623945.2017.1291102

PMCID:: PMC5477721

Abstract Article PDF–624K

Select item 103619003.

Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development

Adam P. Golding, Benjamin Ferrier, Laura A. New, Peihua Lu, Claire E. Martin, Erka Shata, Robert A. Jones, Roger A. Moorehead, Nina Jones

J Mammary Gland Biol Neoplasia. 2023; 28(1): 19. Published online 2023 Jul 21. doi: 10.1007/s10911-023-09541-1

PMCID:: PMC10361900

Abstract Article PDF–6.0M

Select item 94131534.

Endothelial NCK2 promotes atherosclerosis progression in male but not female Nck1-null atheroprone mice

Briana C. Bywaters, Gladys Pedraza, Andreea Trache, Gonzalo M. Rivera

Front Cardiovasc Med. 2022; 9: 955027. Published online 2022 Aug 12. doi: 10.3389/fcvm.2022.955027

PMCID:: PMC9413153

Abstract Article PDF–3.5M

Select item 46875725.

Nck influences preosteoblastic/osteoblastic migration and bone mass

Smriti Aryal A.C, Kentaro Miyai, Yayoi Izu, Tadayoshi Hayata, Takuya Notomi, Masaki Noda, Yoichi Ezura

Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50): 15432–15437. Published online 2015 Nov 30. doi: 10.1073/pnas.1518253112

PMCID:: PMC4687572

Abstract Article PDF–1.1M

Select item 29325786.

Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire

Edwige Roy, Dieudonnée Togbe, Amy D. Holdorf, Dmitry Trubetskoy, Sabrina Nabti, Günter Küblbeck, Alexandra Klevenz, Annette Kopp-Schneider, Frank Leithäuser, Peter Möller, Friedhelm Bladt, Günter Hämmerling, Bernd Arnold, Tony Pawson, Anna Tafuri

Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35): 15529–15534. Published online 2010 Aug 13. doi: 10.1073/pnas.1009743107

PMCID:: PMC2932578

Abstract Article PDF–897K

Select item 29093197.

Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation

Stanley S. Stylli, Stacey T. T. I, Anne M. Verhagen, San San Xu, Ian Pass, Sara A. Courtneidge, Peter Lock

J Cell Sci. 2009 Aug 1; 122(15): 2727–2740. Published online 2009 Jul 13. doi: 10.1242/jcs.046680

PMCID:: PMC2909319

Abstract Article

Select item 24092518.

Nck adaptor proteins control the organization of neuronal circuits important for walking

James P. Fawcett, John Georgiou, Julie Ruston, Friedhelm Bladt, Andrew Sherman, Neil Warner, Bechara J. Saab, Rizaldy Scott, John C. Roder, Tony Pawson

Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52): 20973–20978. Published online 2007 Dec 18. doi: 10.1073/pnas.0710316105

PMCID:: PMC2409251

Abstract Article PDF–1.8M

Select item 39226679.

SKAP2, a novel target of HSF4b, associates with NCK2/F-actin at membrane ruffles and regulates actin reorganization in lens cell

Li Zhou, Zhenguo Zhang, Yufang Zheng, Yufei Zhu, Zejun Wei, Heng Xu, Quan Tang, Xiangyin Kong, Landian Hu

J Cell Mol Med. 2011 Apr; 15(4): 783–795. Published online 2010 Mar 9. doi: 10.1111/j.1582-4934.2010.01048.x

PMCID:: PMC3922667

Abstract Article PDF–1.3M

Select item 269346110.

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements

Alan Huett, John M Leong, Daniel K. Podolsky, Ramnik J. Xavier

Exp Cell Res. Author manuscript; available in PMC 2010 Jul 15.

Published in final edited form as: Exp Cell Res. 2009 Jul 15; 315(12): 2001–2011. Published online 2009 Apr 14. doi: 10.1016/j.yexcr.2009.04.003

PMCID:: PMC2693461

Abstract Article PDF–2.6M

Select item 147669411.

Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B

G. M. Rivera, S. Antoku, S. Gelkop, N. Y. Shin, S. K. Hanks, T. Pawson, B. J. Mayer

Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25): 9536–9541. Published online 2006 Jun 12. doi: 10.1073/pnas.0603786103

PMCID:: PMC1476694

Abstract Article PDF–2.3M

Select item 801121212.

Selective role of Nck1 in atherogenic inflammation and plaque formation

Mabruka Alfaidi, Christina H. Acosta, Dongdong Wang, James G. Traylor, A. Wayne Orr

J Clin Invest. 2020 Aug 3; 130(8): 4331–4347. Published online 2020 Jul 13. doi: 10.1172/JCI135552

PMCID:: PMC8011212

Abstract Article PDF–21M

Select item 266206813.

Nck Adapters Are Involved in the Formation of Dorsal Ruffles, Cell Migration, and Rho Signaling Downstream of the Platelet-derived Growth Factor β Receptor

Aino Ruusala, Tony Pawson, Carl-Henrik Heldin, Pontus Aspenström

J Biol Chem. 2008 Oct 31; 283(44): 30034–30044. doi: 10.1074/jbc.M800913200

PMCID:: PMC2662068

Abstract Article PDF–1.4M

Select item 270968614.

Nck Proteins Maintain the Adult Glomerular Filtration Barrier

Nina Jones, Laura A. New, Megan A. Fortino, Vera Eremina, Julie Ruston, Ivan M. Blasutig, Lamine Aoudjit, Youling Zou, Xiuwen Liu, Guo-Liang Yu, Tomoko Takano, Susan E. Quaggin, Tony Pawson

J Am Soc Nephrol. 2009 Jul; 20(7): 1533–1543. doi: 10.1681/ASN.2009010056

PMCID:: PMC2709686

Abstract Article

Select item 438721615.

Requisite Role for Nck Adaptors in Cardiovascular Development, Endothelial-to-Mesenchymal Transition, and Directed Cell Migration

Derek L. Clouthier, Cameron N. Harris, Richard A. Harris, Claire E. Martin, Mira C. Puri, Nina Jones

Mol Cell Biol. 2015 May; 35(9): 1573–1587. Prepublished online 2015 Feb 17. Published online 2015 Apr 6. doi: 10.1128/MCB.00072-15

PMCID:: PMC4387216

Abstract Article PDF–4.4M

Select item 266108416.

Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

Nan-Jie Xu, Mark Henkemeyer

Nat Neurosci. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: Nat Neurosci. 2009 Mar; 12(3): 268–276. Published online 2009 Feb 1. doi: 10.1038/nn.2254

PMCID:: PMC2661084

Abstract Article PDF–1.6M

Select item 23030617.

Nckβ Interacts with Tyrosine-Phosphorylated Disabled 1 and Redistributes in Reelin-Stimulated Neurons

Albéna Pramatarova, Pawel G. Ochalski, Kelian Chen, Andrea Gropman, Sage Myers, Kyung-Tai Min, Brian W. Howell

Mol Cell Biol. 2003 Oct; 23(20): 7210–7221. doi: 10.1128/MCB.23.20.7210-7221.2003

PMCID:: PMC230306

Abstract Article PDF–1010K

Select item 16485518.

The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network

Friedhelm Bladt, Elke Aippersbach, Sigal Gelkop, Geraldine A. Strasser, Piers Nash, Anna Tafuri, Frank B. Gertler, Tony Pawson

Mol Cell Biol. 2003 Jul; 23(13): 4586–4597. doi: 10.1128/MCB.23.13.4586-4597.2003

PMCID:: PMC164855

Abstract Article PDF–1.3M

Select item 5003019.

High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains.

B Margolis, O Silvennoinen, F Comoglio, C Roonprapunt, E Skolnik, A Ullrich, J Schlessinger

Proc Natl Acad Sci U S A. 1992 Oct 1; 89(19): 8894–8898. doi: 10.1073/pnas.89.19.8894

PMCID:: PMC50030

Summary Page Browse PDF–1.3M

Select item 472959920.

Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neo-Vascularization

Alexandre Dubrac, Gael Genet, Roxana Ola, Feng Zhang, Laurence Pibouin-Fragner, Jinah Han, Jiasheng Zhang, Jean-Léon Thomas, Alain Chedotal, Martin A. Schwartz, Anne Eichmann

Circulation. Author manuscript; available in PMC 2017 Jan 26.

Published in final edited form as: Circulation. 2016 Jan 26; 133(4): 409–421. Published online 2015 Dec 9. doi: 10.1161/CIRCULATIONAHA.115.017537