PMC Links for Gene (Select 178847) - PMC

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Items: 14

Select item 104329391.

sut-2 loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a C. elegans model of tau toxicity

Heather N Currey, Brian C. Kraemer, Nicole F Liachko

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000844. Published online 2023 Aug 3. doi: 10.17912/micropub.biology.000844

PMCID:: PMC10432939

Abstract Article PDF–922K

Select item 103213832.

Sut-6/NIPP1 modulates tau toxicity

R L Kow, A H Black, B P Henderson, B C Kraemer

Hum Mol Genet. 2023 Jul 15; 32(14): 2292–2306. Published online 2023 Mar 31. doi: 10.1093/hmg/ddad049

PMCID:: PMC10321383

Abstract Article PDF–1.9M

Select item 90665183.

TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans

Caitlin S. Latimer, Jade G. Stair, Joshua C. Hincks, Heather N. Currey, Thomas D. Bird, C. Dirk Keene, Brian C. Kraemer, Nicole F. Liachko

Dis Model Mech. 2022 Apr 1; 15(4): dmm049323. Published online 2022 Apr 27. doi: 10.1242/dmm.049323

PMCID:: PMC9066518

Abstract Article

Select item 31037134.

The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?

Jeanna M. Wheeler, Chris R. Guthrie, Brian C. Kraemer

Biochem Soc Trans. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Biochem Soc Trans. 2010 Aug; 38(4): 973–976. doi: 10.1042/BST0380973

PMCID:: PMC3103713

Abstract Article PDF–111K

Select item 30806095.

MSUT2 is a determinant of susceptibility to tau neurotoxicity

Chris R. Guthrie, Lynne Greenup, James B. Leverenz, Brian C. Kraemer

Hum Mol Genet. 2011 May 15; 20(10): 1989–1999. Published online 2011 Feb 25. doi: 10.1093/hmg/ddr079

PMCID:: PMC3080609

Abstract Article PDF–388K

Select item 99105886.

SPOP loss of function protects against tauopathy

Randall J. Eck, Rebecca L. Kow, Aristide H. Black, Nicole F. Liachko, Brian C. Kraemer

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2207250120. Published online 2022 Dec 27. doi: 10.1073/pnas.2207250120

PMCID:: PMC9910588

Abstract Article PDF–2.8M

Select item 80929747.

Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.

Rebecca L. Kow, Timothy J. Strovas, Pamela J. McMillan, Ashley M. Jacobi, Mark A. Behlke, Aleen D. Saxton, Caitlin S. Latimer, C. Dirk Keene, Brian C. Kraemer

Neurobiol Dis. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Neurobiol Dis. 2021 Jan; 147: 105148. Published online 2020 Oct 25. doi: 10.1016/j.nbd.2020.105148

PMCID:: PMC8092974

Abstract Article PDF–1.7M

Select item 27222258.

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

Chris R. Guthrie, Gerard D. Schellenberg, Brian C. Kraemer

Hum Mol Genet. 2009 May 15; 18(10): 1825–1838. Published online 2009 Mar 9. doi: 10.1093/hmg/ddp099

PMCID:: PMC2722225

Abstract Article PDF–643K

Select item 35047179.

Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis

E D Crawford, J E Seaman, A E Barber, II, D C David, P C Babbitt, A L Burlingame, J A Wells

Cell Death Differ. 2012 Dec; 19(12): 2040–2048. Published online 2012 Aug 24. doi: 10.1038/cdd.2012.99

PMCID:: PMC3504717

Abstract Article PDF–932K

Select item 485894510.

In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics

Jia-Xuan Chen, Patricia G. Cipriani, Desirea Mecenas, Jolanta Polanowska, Fabio Piano, Kristin C. Gunsalus, Matthias Selbach

Mol Cell Proteomics. 2016 May; 15(5): 1642–1657. Published online 2016 Feb 24. doi: 10.1074/mcp.M115.053975

PMCID:: PMC4858945

Abstract Article PDF–3.1M

Select item 833118311.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 799517612.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4