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Items: 1 to 20 of 662

1.
Sleep Disruption Precedes Forebrain Synaptic Tau Burden and Contributes to Cognitive Decline in a Sex-Dependent Manner in the P301S Tau Transgenic Mouse Model
Shenée C. Martin, Kathryn K. Joyce, Julia S. Lord, Kathryn M. Harper, Viktoriya D. Nikolova, Todd J. Cohen, Sheryl S. Moy, Graham H. Diering
eNeuro. 2024 Jun; 11(6): ENEURO.0004-24.2024. Prepublished online 2024 Jun 10. Published online 2024 Jun 14. doi: 10.1523/ENEURO.0004-24.2024
PMCID:
PMC11209651
AbstractArticlePDF–1.6M
2.
Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo
Pranav Vemula, Kathleen M. Schoch, Timothy M. Miller
Front Mol Neurosci. 2023; 16: 1320182. Published online 2023 Dec 18. doi: 10.3389/fnmol.2023.1320182
PMCID:
PMC10773814
AbstractArticlePDF–10M
3.
Motor Activity-Induced White Matter Repair in White Matter Stroke
Miguel A. Marin, Amy J. Gleichman, Xiaofei Wei, Daniel S. Whittaker, Istvan Mody, Christopher S. Colwell, S. Thomas Carmichael
J Neurosci. 2023 Nov 29; 43(48): 8126–8139. doi: 10.1523/JNEUROSCI.0631-23.2023
PMCID:
PMC10697402
AbstractArticlePDF–8.4M
4.
Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
Matthew J. Benskey, Spencer Panoushek, Takashi Saito, Takaomi C. Saido, Tessa Grabinski, Nicholas M. Kanaan
Front Aging Neurosci. 2023; 15: 1265151. Published online 2023 Sep 29. doi: 10.3389/fnagi.2023.1265151
PMCID:
PMC10576558
AbstractArticlePDF–14M
5.
Localization, induction, and cellular effects of tau phosphorylated at threonine 217
Binita Rajbanshi, Anuj Guruacharya, James W. Mandell, George S. Bloom
Alzheimers Dement. Author manuscript; available in PMC 2024 Jul 1.
Published in final edited form as: Alzheimers Dement. 2023 Jul; 19(7): 2874–2887. Published online 2023 Jan 12. doi: 10.1002/alz.12892
PMCID:
PMC10336182
AbstractArticlePDF–3.7M
6.
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy
Stacy A. Hussong, Andy Q. Banh, Candice E. Van Skike, Angela O. Dorigatti, Stephen F. Hernandez, Matthew J. Hart, Beatriz Ferran, Haneen Makhlouf, Maria Gaczynska, Pawel A. Osmulski, Salome A. McAllen, Kelly T. Dineley, Zoltan Ungvari, Viviana I. Perez, Rakez Kayed, Veronica Galvan
Nat Commun. 2023; 14: 2367. Published online 2023 Apr 25. doi: 10.1038/s41467-023-37840-y
PMCID:
PMC10126555
AbstractArticlePDF–4.4M
7.
Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse
Pol Andrés-Benito, África Flores, Sara Busquet-Areny, Margarita Carmona, Karina Ausín, Paz Cartas-Cejudo, Mercedes Lachén-Montes, José Antonio Del Rio, Joaquín Fernández-Irigoyen, Enrique Santamaría, Isidro Ferrer
Int J Mol Sci. 2023 Apr; 24(7): 6559. Published online 2023 Mar 31. doi: 10.3390/ijms24076559
PMCID:
PMC10095510
AbstractArticlePDF–5.6M
8.
A seeding-based neuronal model of tau aggregation for use in drug discovery
Ines S. Amorim, Sylvie Challal, Laetitia Cistarelli, Thierry Dorval, Laurene Abjean, Manuelle Touzard, Nicolas Arbez, Arnaud François, Fany Panayi, Ross Jeggo, Erika Cecon, Atsuro Oishi, Julie Dam, Ralf Jockers, Patricia Machado
PLoS One. 2023; 18(4): e0283941. Published online 2023 Apr 4. doi: 10.1371/journal.pone.0283941
PMCID:
PMC10072482
AbstractArticlePDF–3.1M
9.
Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer’s disease
Kanza M. Khan, Nagalakshmi Balasubramanian, Gabriel Gaudencio, Ruixiang Wang, Govindhasamy Pushpavathi Selvakumar, Louis Kolling, Samantha Pierson, Satya M. Tadinada, Ted Abel, Marco Hefti, Catherine A. Marcinkiewcz
Acta Neuropathol Commun. 2023; 11: 57. Published online 2023 Apr 3. doi: 10.1186/s40478-023-01546-5
PMCID:
PMC10069039
AbstractArticlePDF–7.0M
10.
Tau phosphorylation and PAD exposure in regulation of axonal growth
S. L. Morris, S. T. Brady
Front Cell Dev Biol. 2022; 10: 1023418. Published online 2023 Jan 18. doi: 10.3389/fcell.2022.1023418
PMCID:
PMC9893789
AbstractArticlePDF–3.0M
11.
A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice
Susan Barendrecht, An Schreurs, Stefanie Geissler, Victor Sabanov, Victoria Ilse, Vera Rieckmann, Rico Eichentopf, Anja Künemund, Benjamin Hietel, Sebastian Wussow, Katrin Hoffmann, Kerstin Körber-Ferl, Ravi Pandey, Gregory W. Carter, Hans-Ulrich Demuth, Max Holzer, Steffen Roßner, Stephan Schilling, Christoph Preuss, Detlef Balschun, Holger Cynis
Alzheimers Res Ther. 2023; 15: 16. Published online 2023 Jan 14. doi: 10.1186/s13195-022-01144-y
PMCID:
PMC9840277
AbstractArticlePDF–8.1M
12.
Common and Specific Marks of Different Tau Strains Following Intra-Hippocampal Injection of AD, PiD, and GGT Inoculum in hTau Transgenic Mice
Isidro Ferrer, Pol Andrés-Benito, Margarita Carmona, José Antonio del Rio
Int J Mol Sci. 2022 Dec; 23(24): 15940. Published online 2022 Dec 14. doi: 10.3390/ijms232415940
PMCID:
PMC9787745
AbstractArticlePDF–4.2M
13.
Testosterone attenuates sevoflurane-induced tau phosphorylation and cognitive impairment in neonatal male mice
Yongyan Yang, Feng Liang, Jie Gao, Yuanlin Dong, Yiying Zhang, Guang Yang, Sulpicio G. Soriano, Hua-Jun Feng, Zhongcong Xie
Br J Anaesth. 2021 Dec; 127(6): 929–941. Published online 2021 Oct 20. doi: 10.1016/j.bja.2021.08.028
PMCID:
PMC9642834
AbstractArticlePDF–1.7M
14.
Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy
Scott C. Vermilyea, Anne Christensen, Joyce Meints, Balvindar Singh, Héctor Martell-Martínez, Md. Razaul Karim, Michael K. Lee
Transl Neurodegener. 2022; 11: 34. Published online 2022 Jul 1. doi: 10.1186/s40035-022-00309-x
PMCID:
PMC9248195
AbstractArticlePDF–5.1M
15.
Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology
Giavanna Paterno, Brach M. Bell, Kimberly-Marie M. Gorion, Stefan Prokop, Benoit I. Giasson
Acta Neuropathol Commun. 2022; 10: 94. Published online 2022 Jun 28. doi: 10.1186/s40478-022-01394-9
PMCID:
PMC9237980
AbstractArticlePDF–3.1M
16.
Dysregulated Brain Protein Phosphorylation Linked to Increased Human Tau Expression in the hTau Transgenic Mouse Model
Isidro Ferrer, Pol Andrés-Benito, Karina Ausín, Paz Cartas-Cejudo, Mercedes Lachén-Montes, José Antonio del Rio, Joaquín Fernández-Irigoyen, Enrique Santamaría
Int J Mol Sci. 2022 Jun; 23(12): 6427. Published online 2022 Jun 8. doi: 10.3390/ijms23126427
PMCID:
PMC9223516
AbstractArticlePDF–1.0M
17.
Fisetin inhibits tau aggregation by interacting with the protein and preventing the formation of β-strands
Shifeng Xiao, Yafei Lu, Qiuping Wu, Jiaying Yang, Jierui Chen, Suyue Zhong, David Eliezer, Qiulong Tan, Chengchen Wu
Int J Biol Macromol. Author manuscript; available in PMC 2022 May 1.
Published in final edited form as: Int J Biol Macromol. 2021 May 1; 178: 381–393. Published online 2021 Mar 1. doi: 10.1016/j.ijbiomac.2021.02.210
PMCID:
PMC9022726
AbstractArticlePDF–1.5M
18.
Hyperphosphorylated Human Tau Accumulates at the Synapse, Localizing on Synaptic Mitochondrial Outer Membranes and Disrupting Respiration in a Mouse Model of Tauopathy
Andrew J. Trease, Joseph W. George, Nashanthea J. Roland, Eliezer Z. Lichter, Katy Emanuel, Steven Totusek, Howard S. Fox, Kelly L. Stauch
Front Mol Neurosci. 2022; 15: 852368. Published online 2022 Mar 10. doi: 10.3389/fnmol.2022.852368
PMCID:
PMC8960727
AbstractArticlePDF–5.7M
19.
Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model
Hamza Benderradji, Sarra Kraiem, Emilie Courty, Sabiha Eddarkaoui, Cyril Bourouh, Emilie Faivre, Laure Rolland, Emilie Caron, Mélanie Besegher, Frederik Oger, Theo Boschetti, Kévin Carvalho, Bryan Thiroux, Thibaut Gauvrit, Emilie Nicolas, Victoria Gomez-Murcia, Anna Bogdanova, Antonino Bongiovanni, Anne Muhr-Tailleux, Steve Lancel, Kadiombo Bantubungi, Nicolas Sergeant, Jean-Sebastien Annicotte, Luc Buée, Didier Vieau, David Blum, Valérie Buée-Scherrer
Front Mol Neurosci. 2022; 15: 841892. Published online 2022 Feb 16. doi: 10.3389/fnmol.2022.841892
PMCID:
PMC8889017
AbstractArticlePDF–4.6M
20.
Microtubule-associated protein tau in murine kidney: role in podocyte architecture
Laura Vallés-Saiz, Rocio Peinado-Cahuchola, Jesús Ávila, Félix Hernández
Cell Mol Life Sci. 2022 Feb; 79(2): 97. Published online 2022 Jan 27. doi: 10.1007/s00018-021-04106-z
PMCID:
PMC8794918
AbstractArticlePDF–2.4M

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