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Select item 110990351.

FOXC1 regulates endothelial CD98 (LAT1/4F2hc) expression in retinal angiogenesis and blood-retina barrier formation

Teena Bhakuni, Pieter R. Norden, Naoto Ujiie, Can Tan, Sun Kyong Lee, Thomas Tedeschi, Yi-Wen Hsieh, Ying Wang, Ting Liu, Amani A. Fawzi, Tsutomu Kume

Nat Commun. 2024; 15: 4097. Published online 2024 May 16. doi: 10.1038/s41467-024-48134-2

PMCID:: PMC11099035

Abstract Article PDF–25M

Select item 68158492.

FOXC1 up‐regulates the expression of toll‐like receptors in myocardial ischaemia

Shao‐Ping Zhang, Ruo‐Han Yang, Jia Shang, Ting Gao, Rui Wang, Xiao‐Dong Peng, Xiao Miao, Lei Pan, Wen‐Jun Yuan, Li Lin, Qi‐Kuan Hu

J Cell Mol Med. 2019 Nov; 23(11): 7566–7580. Published online 2019 Sep 13. doi: 10.1111/jcmm.14626

PMCID:: PMC6815849

Abstract Article PDF–2.4M

Select item 63224363.

FOXC1 Is Enriched in the Mammary Luminal Progenitor Population, but Is Not Necessary for Mouse Mammary Ductal Morphogenesis

Gina M. Sizemore, Steven T. Sizemore, Bhupinder Pal, Christine N. Booth, Darcie D. Seachrist, Fadi W. Abdul-Karim, Tsutomu Kume, Ruth A. Keri

Biol Reprod. 2013 Jul; 89(1): 10, 1-10. doi: 10.1095/biolreprod.113.108001

PMCID:: PMC6322436

Abstract Article PDF–1.1M

Select item 56566184.

Inhibition of lobuloalveolar development by FOXC1 overexpression in the mouse mammary gland

Bowen Gao, Ying Qu, Bingchen Han, Yoshiko Nagaoka, Makoto Katsumata, Nan Deng, Shikha Bose, Liting Jin, Armando E. Giuliano, Xiaojiang Cui

Sci Rep. 2017; 7: 14017. Published online 2017 Oct 25. doi: 10.1038/s41598-017-14342-8

PMCID:: PMC5656618

Abstract Article PDF–2.2M

Select item 51835335.

Foxc1 ablated mice are anhidrotic and recapitulate features of human miliaria sweat retention disorder

Chang-Yi Cui, Ryuga Ishii, Dean P. Campbell, Marc Michel, Yulan Piao, Tsutomu Kume, David Schlessinger

J Invest Dermatol. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: J Invest Dermatol. 2017 Jan; 137(1): 38–45. Published online 2016 Sep 1. doi: 10.1016/j.jid.2016.08.012

PMCID:: PMC5183533

Abstract Article PDF–2.4M

Select item 48012486.

FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential

Kenneth Lay, Tsutomu Kume, Elaine Fuchs

Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11): E1506–E1515. Published online 2016 Feb 24. doi: 10.1073/pnas.1601569113

PMCID:: PMC4801248

Abstract Article PDF–2.3M

Select item 52716067.

Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms

Parthiv Haldipur, Derek Dang, Kimberly A Aldinger, Olivia K Janson, Fabien Guimiot, Homa Adle-Biasette, William B Dobyns, Joseph R Siebert, Rosa Russo, Kathleen J Millen

eLife. 2017; 6: e20898. Published online 2017 Jan 16. doi: 10.7554/eLife.20898

PMCID:: PMC5271606

Abstract Article PDF–7.8M

Select item 34923078.

Initiation of Early Osteoblast Differentiation Events through the Direct Transcriptional Regulation of Msx2 by FOXC1

Farideh Mirzayans, Rotem Lavy, Jonathan Penner-Chea, Fred B. Berry

PLoS One. 2012; 7(11): e49095. Published online 2012 Nov 7. doi: 10.1371/journal.pone.0049095

PMCID:: PMC3492307

Abstract Article PDF–444K

Select item 34354829.

Generation of conditional alleles for Foxc1 and Foxc2 in mice

Amy Sasman, Carey Nassano-Miller, Kyoo Seok Shim, Hyun Young Koo, Ting Liu, Kathryn M. Schultz, Meredith Millay, Atsushi Nanano, Myengmo Kang, Takashi Suzuki, Tsutomu Kume

Genesis. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Genesis. 2012 Oct; 50(10): 766–774. Published online 2012 May 14. doi: 10.1002/dvg.22036

PMCID:: PMC3435482

Abstract Article PDF–3.3M

Select item 730288010.

Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation

Pieter R Norden, Amélie Sabine, Ying Wang, Cansaran Saygili Demir, Ting Liu, Tatiana V Petrova, Tsutomu Kume

eLife. 2020; 9: e53814. Published online 2020 Jun 8. doi: 10.7554/eLife.53814

PMCID:: PMC7302880

Abstract Article PDF–16M

Select item 707620711.

Generation and validation of a PITX2–EGFP reporter line of human induced pluripotent stem cells enables isolation of periocular mesenchymal cells

Toru Okubo, Ryuhei Hayashi, Shun Shibata, Yuji Kudo, Yuki Ishikawa, Saki Inoue, Yuki Kobayashi, Ai Honda, Yoichi Honma, Satoshi Kawasaki, Kohji Nishida

J Biol Chem. 2020 Mar 13; 295(11): 3456–3465. Published online 2020 Feb 7. doi: 10.1074/jbc.RA119.010713

PMCID:: PMC7076207

Abstract Article PDF–2.9M

Select item 482814012.

Foxc1 reinforces quiescence in self-renewing hair follicle stem cells

Li Wang, Julie A. Siegenthaler, Robin D. Dowell, Rui Yi

Science. Author manuscript; available in PMC 2016 Aug 5.

Published in final edited form as: Science. 2016 Feb 5; 351(6273): 613–617. doi: 10.1126/science.aad5440

PMCID:: PMC4828140

Abstract Article PDF–1.5M

Select item 319275413.

Foxf2: A Novel Locus for Anterior Segment Dysgenesis Adjacent to the Foxc1 Gene

Richard McKeone, Helena Vieira, Kevin Gregory-Evans, Cheryl Y. Gregory-Evans, Paul Denny

PLoS One. 2011; 6(10): e25489. Published online 2011 Oct 13. doi: 10.1371/journal.pone.0025489

PMCID:: PMC3192754

Abstract Article PDF–599K

Select item 137754214.

Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly.

A J Mears, T Jordan, F Mirzayans, S Dubois, T Kume, M Parlee, R Ritch, B Koop, W L Kuo, C Collins, J Marshall, D B Gould, W Pearce, P Carlsson, S Enerbäck, J Morissette, S Bhattacharya, B Hogan, V Raymond, M A Walter

Am J Hum Genet. 1998 Nov; 63(5): 1316–1328. doi: 10.1086/302109

PMCID:: PMC1377542

Summary PDF–1.7M

Select item 1032807815.

Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia–reperfusion injury

Can Tan, Pieter R Norden, Wei Yu, Ting Liu, Naoto Ujiie, Sun Kyong Lee, Xiaocai Yan, Yaryna Dyakiv, Kazushi Aoto, Sagrario Ortega, Isabelle G De Plaen, Venkatesh Sampath, Tsutomu Kume

EMBO Rep. 2023 Jul; 24(7): e56030. Published online 2023 May 8. doi: 10.15252/embr.202256030

PMCID:: PMC10328078

Abstract Article PDF–28M

Select item 602619216.

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

Alison Hirukawa, Harvey W. Smith, Dongmei Zuo, Catherine R. Dufour, Paul Savage, Nicholas Bertos, Radia M. Johnson, Tung Bui, Guillaume Bourque, Mark Basik, Vincent Giguère, Morag Park, William J. Muller

Nat Commun. 2018; 9: 2547. Published online 2018 Jun 29. doi: 10.1038/s41467-018-04864-8

PMCID:: PMC6026192

Abstract Article PDF–2.6M

Select item 256711217.

The role of the forkhead transcription factor, Foxc1, in the development of the mouse lacrimal gland

Deidre Mattiske, Paula Sommer, Susan H. Kidson, Brigid L.M. Hogan

Dev Dyn. Author manuscript; available in PMC 2008 Oct 14.

Published in final edited form as: Dev Dyn. 2006 Apr; 235(4): 1074–1080. doi: 10.1002/dvdy.20702

PMCID:: PMC2567112

Abstract Article PDF–7.5M

Select item 239877418.

Foxc Transcription Factors Directly Regulate Dll4 and Hey2 Expression by Interacting with the VEGF-Notch Signaling Pathways in Endothelial Cells

Hisaki Hayashi, Tsutomu Kume

PLoS One. 2008; 3(6): e2401. Published online 2008 Jun 11. doi: 10.1371/journal.pone.0002401

PMCID:: PMC2398774

Abstract Article PDF–643K

Select item 226541919.

Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration

Hisaki Hayashi, Tsutomu Kume

Biochem Biophys Res Commun. Author manuscript; available in PMC 2009 Mar 14.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Mar 14; 367(3): 584–589. Published online 2008 Jan 8. doi: 10.1016/j.bbrc.2007.12.183