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Items: 1 to 20 of 180

1.
Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance
Lili Zheng, Junqiu Jia, Yan Chen, Renyuan Liu, Runjing Cao, Manlin Duan, Meijuan Zhang, Yun Xu
J Neuroinflammation. 2022; 19: 128. Published online 2022 May 31. doi: 10.1186/s12974-022-02480-4
PMCID:
PMC9153105
AbstractArticlePDF–10M
2.
Defective Efferocytosis in a Murine Model of Sjögren’s Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor
Richard Witas, Astrid Rasmussen, Robert H. Scofield, Lida Radfar, Donald U. Stone, Kiely Grundahl, David Lewis, Kathy L. Sivils, Christopher J. Lessard, A. Darise Farris, Cuong Q. Nguyen
Int J Mol Sci. 2021 Sep; 22(18): 9711. Published online 2021 Sep 8. doi: 10.3390/ijms22189711
PMCID:
PMC8466327
AbstractArticlePDF–3.3M
3.
Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
Haijian Wu, Jingwei Zheng, Shenbin Xu, Yuanjian Fang, Yingxi Wu, Jianxiong Zeng, Anwen Shao, Ligen Shi, Jianan Lu, Shuhao Mei, Xiaoyu Wang, Xinying Guo, Yirong Wang, Zhen Zhao, Jianmin Zhang
J Neuroinflammation. 2021; 18: 2. Published online 2021 Jan 5. doi: 10.1186/s12974-020-02041-7
PMCID:
PMC7787000
AbstractArticlePDF–4.4M
4.
MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin‐Producing Reparative Macrophages After Myocardial Infarction
Kohsuke Shirakawa, Jin Endo, Masaharu Kataoka, Yoshinori Katsumata, Atsushi Anzai, Hidenori Moriyama, Hiroki Kitakata, Takahiro Hiraide, Seien Ko, Shinichi Goto, Genki Ichihara, Keiichi Fukuda, Tohru Minamino, Motoaki Sano
J Am Heart Assoc. 2020 Sep 15; 9(18): e017071. Published online 2020 Aug 31. doi: 10.1161/JAHA.120.017071
PMCID:
PMC7726992
AbstractArticlePDF–2.7M
5.
Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency
Deborah S. Lew, Francesca Mazzoni, Silvia C. Finnemann
Front Immunol. 2020; 11: 1463. Published online 2020 Jul 16. doi: 10.3389/fimmu.2020.01463
PMCID:
PMC7381113
AbstractArticlePDF–1.8M
6.
Mechanism of enhanced MerTK-dependent macrophage efferocytosis by extracellular vesicles
Geoffrey de Couto, Ervin Jaghatspanyan, Matthew DeBerge, Weixin Liu, Kristin Luther, Yizhou Wang, Jie Tang, Edward B. Thorp, Eduardo Marbán
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Oct; 39(10): 2082–2096. Published online 2019 Aug 22. doi: 10.1161/ATVBAHA.119.313115
PMCID:
PMC6760997
AbstractArticlePDF–3.4M
7.
Receptor Tyrosine Kinase MerTK Suppresses an Allogenic Type I IFN Response to Promote Transplant Tolerance
Lei Zhang, Mathew DeBerge, Jiaojin Wang, Anil Dangi, Xiaomin Zhang, Samantha Schroth, Zheng Zhang, Edward Thorp, Xunrong Luo
Am J Transplant. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Am J Transplant. 2019 Mar; 19(3): 674–685. Published online 2018 Sep 24. doi: 10.1111/ajt.15087
PMCID:
PMC6393931
AbstractArticlePDF–1.0M
8.
Mer-mediated eosinophil efferocytosis regulates resolution of allergic airway inflammation
Jennifer M. Felton, Christopher D. Lucas, David A. Dorward, Rodger Duffin, Tiina Kipari, Sonja Vermeren, Calum T. Robb, Kenneth G. MacLeod, Bryan Serrels, Jürgen Schwarze, Christopher Haslett, Ian Dransfield, Adriano G. Rossi
J Allergy Clin Immunol. 2018 Dec; 142(6): 1884–1893.e6. doi: 10.1016/j.jaci.2018.01.029
PMCID:
PMC6281028
AbstractArticlePDF–3.6M
9.
MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity
Alisa B. Lee-Sherick, Kristen M. Jacobsen, Curtis J. Henry, Madeline G. Huey, Rebecca E. Parker, Lauren S. Page, Amanda A. Hill, Xiaodong Wang, Stephen V. Frye, H. Shelton Earp, Craig T. Jordan, Deborah DeRyckere, Douglas K. Graham
JCI Insight. 2018 Nov 2; 3(21): e97941. Published online 2018 Nov 2. doi: 10.1172/jci.insight.97941
Correction in:
JCI Insight. 2020 Dec 3; 5(23): e145847.
PMCID:
PMC6238750
AbstractArticlePDF–9.8M
10.
Mechanism of Mer receptor tyrosine kinase inhibition of glomerular endothelial cell inflammation
Yuxuan Zhen, Fred D Finkelman, Wen-Hai Shao
J Leukoc Biol. Author manuscript; available in PMC 2019 Apr 1.
Published in final edited form as: J Leukoc Biol. 2018 Apr; 103(4): 709–717. Published online 2018 Jan 19. doi: 10.1002/JLB.3A0917-368R
PMCID:
PMC6150462
AbstractArticlePDF–1.7M
11.
Context-dependent compensation among phosphatidylserine-recognition receptors
Kristen K. Penberthy, Claudia Rival, Laura S. Shankman, Michael H. Raymond, Jianye Zhang, Justin S. A. Perry, Chang Sup Lee, Claudia Z. Han, Suna Onengut-Gumuscu, Krzysztof Palczewski, Jeffrey J. Lysiak, Kodi S. Ravichandran
Sci Rep. 2017; 7: 14623. Published online 2017 Nov 7. doi: 10.1038/s41598-017-15191-1
PMCID:
PMC5676788
AbstractArticlePDF–3.8M
12.
Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy
Marka R. Crittenden, Jason Baird, David Friedman, Talicia Savage, Lauren Uhde, Alejandro Alice, Benjamin Cottam, Kristina Young, Pippa Newell, Cynthia Nguyen, Shelly Bambina, Gwen Kramer, Emmanuel Akporiaye, Anna Malecka, Andrew Jackson, Michael J. Gough
Oncotarget. 2016 Nov 29; 7(48): 78653–78666. Published online 2016 Sep 2. doi: 10.18632/oncotarget.11823
PMCID:
PMC5346667
AbstractArticlePDF–2.2M
13.
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation
Bishuang Cai, Edward B. Thorp, Amanda C. Doran, Manikandan Subramanian, Brian E. Sansbury, Chyuan-Sheng Lin, Matthew Spite, Gabrielle Fredman, Ira Tabas
Proc Natl Acad Sci U S A. 2016 Jun 7; 113(23): 6526–6531. Published online 2016 May 19. doi: 10.1073/pnas.1524292113
PMCID:
PMC4988577
AbstractArticlePDF–1.0M
14.
Mertk Deficiency Alters Expression of microRNAs in the Retinal Pigment Epithelium Cells
Yong Tang, Qingjun Lu, Yunrong Wei, Lixia Han, Rui Ji, Qiutang Li, Qingxian Lu
Metab Brain Dis. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: Metab Brain Dis. 2015 Aug; 30(4): 943–950. Published online 2015 Jan 22. doi: 10.1007/s11011-015-9653-5
PMCID:
PMC4492868
AbstractArticlePDF–2.2M
15.
Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution
Jamie C. Stanford, Christian Young, Donna Hicks, Philip Owens, Andrew Williams, David B. Vaught, Meghan M. Morrison, Jiyeon Lim, Michelle Williams, Dana M. Brantley-Sieders, Justin M. Balko, Debra Tonetti, H. Shelton Earp, III, Rebecca S. Cook
J Clin Invest. 2014 Nov 3; 124(11): 4737–4752. Published online 2014 Sep 24. doi: 10.1172/JCI76375
PMCID:
PMC4347249
AbstractArticlePDF–8.2M
16.
Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis
Ah-Lai Law, Célia Parinot, Jonathan Chatagnon, Basile Gravez, José-Alain Sahel, Shomi S. Bhattacharya, Emeline F. Nandrot
J Biol Chem. 2015 Feb 20; 290(8): 4941–4952. Published online 2014 Dec 23. doi: 10.1074/jbc.M114.628297
PMCID:
PMC4335232
AbstractArticlePDF–2.3M
17.
Mertk Deficiency Affects Macrophage Directional Migration via Disruption of Cytoskeletal Organization
Yong Tang, Shen Wu, Qian Liu, Jiayi Xie, Jingxue Zhang, Dong Han, Qingxian Lu, Qingjun Lu
PLoS One. 2015; 10(1): e0117787. Published online 2015 Jan 24. doi: 10.1371/journal.pone.0117787
PMCID:
PMC4305281
AbstractArticlePDF–6.1M
18.
The Mertk Receptor Tyrosine Kinase Promotes T-B interaction Stimulated by IgD B-cell Receptor Cross-linking
Wen-Hai Shao, Yuxuan Zhen, Fred D. Finkelman, Philip L. Cohen
J Autoimmun. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: J Autoimmun. 2014 Sep; 53: 78–84. Published online 2014 Apr 24. doi: 10.1016/j.jaut.2014.03.004
PMCID:
PMC4162827
AbstractArticlePDF–1.1M
19.
Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through MER Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction
Elaine Wan, Xin Yi Yeap, Shirley Dehn, Rachael Terry, Margaret Novak, Shuang Zhang, Shinichi Iwata, Xiaoqiang Han, Shunichi Homma, Konstantinos Drosatos, Jon Lomasney, David M. Engman, Stephen D. Miller, Douglas E. Vaughan, John P. Morrow, Raj Kishore, Edward B. Thorp
Circ Res. Author manuscript; available in PMC 2014 Sep 27.
Published in final edited form as: Circ Res. 2013 Sep 27; 113(8): 10.1161/CIRCRESAHA.113.301198. Published online 2013 Jul 8. doi: 10.1161/CIRCRESAHA.113.301198
PMCID:
PMC3840464
AbstractArticlePDF–3.2M
20.
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis
Rebecca S. Cook, Kristen M. Jacobsen, Anne M. Wofford, Deborah DeRyckere, Jamie Stanford, Anne L. Prieto, Elizabeth Redente, Melissa Sandahl, Debra M. Hunter, Karen E. Strunk, Douglas K. Graham, H. Shelton Earp, III
J Clin Invest. 2013 Aug 1; 123(8): 3231–3242. Published online 2013 Jul 8. doi: 10.1172/JCI67655
PMCID:
PMC3726162
AbstractArticlePDF–3.7M

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