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Select item 101667121.

Myeloid expression of the anti-apoptotic protein Mcl1 is required in anti-myeloperoxidase vasculitis but myeloperoxidase inhibition is not protective

Fernanda Florez-Barros, Siobhan Bearder, Bengt Kull, Adrian Freeman, Attila Mócsai, Michael G. Robson

Kidney Int. 2023 Jan; 103(1): 134–143. doi: 10.1016/j.kint.2022.08.028

PMCID:: PMC10166712

Abstract Article

Select item 98900322.

Selective inhibition of MCL1 overcomes venetoclax resistance in a murine model of myelodysplastic syndromes

Melissa A. Fischer, Yuanbin Song, Maria P. Arrate, Rana Gbyli, Matthew T. Villaume, Brianna N. Smith, Merrida A. Childress, Thomas P. Stricker, Stephanie Halene, Michael R. Savona

Haematologica. 2023 Feb 1; 108(2): 522–531. Published online 2022 Aug 18. doi: 10.3324/haematol.2022.280631

PMCID:: PMC9890032

Abstract Article PDF–2.2M

Select item 80208953.

MCT1 Deletion in Oligodendrocyte Lineage Cells Causes Late-Onset Hypomyelination and Axonal Degeneration

Thomas Philips, Yevgeniya A. Mironova, Yan Jouroukhin, Jeannie Chew, Svetlana Vidensky, Mohamed H. Farah, Mikhail V. Pletnikov, Dwight E. Bergles, Brett M. Morrison, Jeffrey D. Rothstein

Cell Rep. Author manuscript; available in PMC 2021 Apr 5.

Published in final edited form as: Cell Rep. 2021 Jan 12; 34(2): 108610. doi: 10.1016/j.celrep.2020.108610

PMCID:: PMC8020895

Abstract Article PDF–3.2M

Select item 76651714.

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model

Xufeng Cen, Yanying Chen, Xiaoyan Xu, Ronghai Wu, Fusheng He, Qingwei Zhao, Qiming Sun, Cong Yi, Jie Wu, Ayaz Najafov, Hongguang Xia

Nat Commun. 2020; 11: 5731. Published online 2020 Nov 12. doi: 10.1038/s41467-020-19547-6

PMCID:: PMC7665171

Abstract Article PDF–6.7M

Select item 74946555.

Mcl-1-Mediated Mitochondrial Fission Protects Against Stress but Impairs Cardiac Adaptation to Exercise

Alexandra G. Moyzis, Navraj S. Lally, Wenjing Liang, Leonardo J. Leon, Rita H. Najor, Amabel M. Orogo, Åsa B. Gustafsson

J Mol Cell Cardiol. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: J Mol Cell Cardiol. 2020 Sep; 146: 109–120. Published online 2020 Jul 25. doi: 10.1016/j.yjmcc.2020.07.009

PMCID:: PMC7494655

Abstract Article PDF–2.8M

Select item 73610196.

Mcl-1 protects eosinophils from apoptosis and exacerbates allergic airway inflammation

Jennifer M Felton, David A Dorward, Jennifer A Cartwright, Philippe MD Potey, Calum T Robb, Jingang Gui, Ruth W Craig, Jürgen Schwarze, Christopher Haslett, Rodger Duffin, Ian Dransfield, Christopher D Lucas, Adriano G Rossi

Thorax. 2020 Jul; 75(7): 600–605. Published online 2020 Apr 17. doi: 10.1136/thoraxjnl-2019-213204

PMCID:: PMC7361019

Abstract Article PDF–1.1M

Select item 68034537.

Chymase-Cre; Mcl-1^fl/fl Mice Exhibit Reduced Numbers of Mucosal Mast Cells

Ying Luo, Nicole Meyer, Qingqing Jiao, Jörg Scheffel, Carolin Zimmermann, Martin Metz, Ana Zenclussen, Marcus Maurer, Frank Siebenhaar

Front Immunol. 2019; 10: 2399. Published online 2019 Oct 15. doi: 10.3389/fimmu.2019.02399

PMCID:: PMC6803453

Abstract Article PDF–1.7M

Select item 61872108.

Low‐molecular‐mass hyaluronan induces pulmonary inflammation by up‐regulation of Mcl‐1 to inhibit neutrophil apoptosis via PI3K/Akt1 pathway

Hang Zhao, Yating Ma, Leifang Zhang

Immunology. 2018 Nov; 155(3): 387–395. Published online 2018 Jul 26. doi: 10.1111/imm.12981

PMCID:: PMC6187210

Abstract Article PDF–608K

Select item 57495009.

Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy

Guo Chen, Andrew T. Magis, Ke Xu, Dongkyoo Park, David S. Yu, Taofeek K. Owonikoko, Gabriel L. Sica, Sarah W. Satola, Suresh S. Ramalingam, Walter J. Curran, Paul W. Doetsch, Xingming Deng

J Clin Invest. 2018 Jan 2; 128(1): 500–516. Published online 2017 Dec 11. doi: 10.1172/JCI92742

PMCID:: PMC5749500

Abstract Article PDF–15M

Select item 568634310.

The combination of reduced MCL-1 and standard chemotherapeutics is tolerable in mice

Kerstin Brinkmann, Stephanie Grabow, Craig D Hyland, Charis E Teh, Warren S Alexander, Marco J Herold, Andreas Strasser

Cell Death Differ. 2017 Dec; 24(12): 2032–2043. Published online 2017 Aug 11. doi: 10.1038/cdd.2017.125

PMCID:: PMC5686343

Abstract Article PDF–3.5M

Select item 526101811.

Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability

Casey Ah-Cann, Maximilien Tailler, Andrew J Kueh, Marco J Herold, Joseph T Opferman, Marie-Liesse Asselin-Labat, Philippe Bouillet

Cell Death Dis. 2016 Dec; 7(12): e2490. Published online 2016 Dec 1. doi: 10.1038/cddis.2016.391

PMCID:: PMC5261018

Article PDF–464K

Select item 476993012.

Mcl-1 Regulates Effector and Memory CD8 T-Cell Differentiation During Acute Viral Infection

Eui Ho Kim, Brandon Neldner, Jingang Gui, Ruth W. Craig, M. Suresh

Virology. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Virology. 2016 Mar; 490: 75–82. Published online 2016 Feb 6. doi: 10.1016/j.virol.2016.01.008

PMCID:: PMC4769930

Abstract Article PDF–1.5M

Select item 475139013.

Leishmania donovani Exploits Myeloid Cell Leukemia 1 (MCL-1) Protein to Prevent Mitochondria-dependent Host Cell Apoptosis

Jayeeta Giri, Supriya Srivastav, Moumita Basu, Shreyasi Palit, Purnima Gupta, Anindita Ukil

J Biol Chem. 2016 Feb 12; 291(7): 3496–3507. Published online 2015 Dec 15. doi: 10.1074/jbc.M115.672873

PMCID:: PMC4751390

Abstract Article PDF–2.8M

Select item 458442214.

Mast cell degranulation by a hemolytic lipid toxin decreases GBS colonization and infection

Claire Gendrin, Jay Vornhagen, Lisa Ngo, Christopher Whidbey, Erica Boldenow, Veronica Santana-Ufret, Morgan Clauson, Kellie Burnside, Dionne P. Galloway, Kristina M. Adams Waldorf, Adrian M. Piliponsky, Lakshmi Rajagopal

Sci Adv. 2015 Jul; 1(6): e1400225. Published online 2015 Jul 17. doi: 10.1126/sciadv.1400225

PMCID:: PMC4584422

Abstract Article PDF–2.5M

Select item 350471015.

Elevated Mcl-1 inhibits thymocyte apoptosis and alters thymic selection

K J Campbell, D H D Gray, N Anstee, A Strasser, S Cory

Cell Death Differ. 2012 Dec; 19(12): 1962–1971. Published online 2012 Jun 29. doi: 10.1038/cdd.2012.84

PMCID:: PMC3504710

Abstract Article PDF–2.0M

Select item 340194716.

Anti-Apoptotic MCL-1 Localizes to the Mitochondrial Matrix and Couples Mitochondrial Fusion to Respiration

Rhonda M. Perciavalle, Daniel P. Stewart, Brian Koss, John Lynch, Sandra Milasta, Madhavi Bathina, Jamshid Temirov, Megan M. Cleland, Stéphane Pelletier, John D. Schuetz, Richard J. Youle, Douglas R. Green, Joseph T. Opferman

Nat Cell Biol. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Nat Cell Biol. 2012 Apr 29; 14(6): 575–583. Published online 2012 Apr 29. doi: 10.1038/ncb2488