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Items: 1 to 20 of 24

1.
An Early Axonopathy in a hLRRK2(R1441G) Transgenic Model of Parkinson Disease
Patricia Tagliaferro, Tatyana Kareva, Tinmarla F Oo, Olga Yarygina, Nikolai Kholodilov, Robert E Burke
Neurobiol Dis. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: Neurobiol Dis. 2015 Oct; 82: 359–371. Published online 2015 Jul 17. doi: 10.1016/j.nbd.2015.07.009
PMCID:
PMC4640977
AbstractArticlePDF–2.3M
2.
A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2R1441G) transgenic mouse model of Parkinson’s disease
Brian P. Dranka, Alison Gifford, Donna McAllister, Jacek Zielonka, Joy Joseph, Crystal L. O’Hara, Cheryl L. Stucky, Anumantha G. Kanthasamy, Balaraman Kalyanaraman
Neurosci Lett. Author manuscript; available in PMC 2015 Nov 7.
Published in final edited form as: Neurosci Lett. 2014 Nov 7; 583: 159–164. Published online 2014 Sep 26. doi: 10.1016/j.neulet.2014.09.042
PMCID:
PMC4253647
AbstractArticlePDF–661K
3.
Diapocynin prevents early Parkinson’s disease symptoms in the Leucine-Rich Repeat Kinase 2 (LRRK2R1441G) transgenic mouse
Brian P. Dranka, Alison Gifford, Anamitra Ghosh, Jacek Zielonka, Joy Joseph, Anumantha G. Kanthasamy, Balaraman Kalyanaraman
Neurosci Lett. Author manuscript; available in PMC 2014 Aug 9.
Published in final edited form as: Neurosci Lett. 2013 Aug 9; 549: 57–62. Published online 2013 May 28. doi: 10.1016/j.neulet.2013.05.034
PMCID:
PMC3729885
AbstractArticlePDF–1.5M
4.
Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson’s disease
Yanping Li, Wencheng Liu, Tinmarla F Oo, Lei Wang, Yi Tang, Vernice Jackson-Lewis, Chun Zhou, Kindiya Geghman, Mikhail Bogdanov, Serge Przedborski, M Flint Beal, Robert E Burke, Chenjian Li
Nat Neurosci. Author manuscript; available in PMC 2010 Mar 26.
Published in final edited form as: Nat Neurosci. 2009 Jul; 12(7): 826–828. Published online 2009 Jun 7. doi: 10.1038/nn.2349
PMCID:
PMC2845930
AbstractArticlePDF–1.2M
5.
Alternative Splicing Coupled Nonsense-Mediated Decay Generates Neuronal Cell Type-Specific Expression of SLM Proteins
Lisa Traunmüller, Caroline Bornmann, Peter Scheiffele
J Neurosci. 2014 Dec 10; 34(50): 16755–16761. doi: 10.1523/JNEUROSCI.3395-14.2014
PMCID:
PMC6608507
AbstractArticlePDF–1.6M
6.
14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening
Nicholas J. Lavalley, Sunny R. Slone, Huiping Ding, Andrew B. West, Talene A. Yacoubian
Hum Mol Genet. 2016 Jan 1; 25(1): 109–122. Published online 2015 Nov 5. doi: 10.1093/hmg/ddv453
PMCID:
PMC4690493
AbstractArticlePDF–1.1M
7.
Non-Motor and Motor Features in LRRK2 Transgenic Mice
Zoë Bichler, Han Chi Lim, Li Zeng, Eng King Tan
PLoS One. 2013; 8(7): e70249. Published online 2013 Jul 30. doi: 10.1371/journal.pone.0070249
PMCID:
PMC3728021
AbstractArticlePDF–954K
8.
SAM68-Specific Splicing Is Required for Proper Selection of Alternative 3′ UTR Isoforms in the Nervous System
Yoko Iijima, Masami Tanaka, Satoko Suzuki, David Hauser, Masayuki Tanaka, Chisa Okada, Masatoshi Ito, Noriko Ayukawa, Yuji Sato, Masato Ohtsuka, Peter Scheiffele, Takatoshi Iijima
iScience. 2019 Dec 20; 22: 318–335. Published online 2019 Nov 16. doi: 10.1016/j.isci.2019.11.028
PMCID:
PMC6909182
AbstractArticlePDF–9.8M
9.
Interplay of LRRK2 with chaperone-mediated autophagy
Samantha J. Orenstein, Sheng-Hang Kuo, Inmaculada Tasset, Esperanza Arias, Hiroshi Koga, Irene Fernandez-Carasa, Etty Cortes, Lawrence S. Honig, William Dauer, Antonella Consiglio, Angel Raya, David Sulzer, Ana Maria Cuervo
Nat Neurosci. Author manuscript; available in PMC 2013 Oct 1.
Published in final edited form as: Nat Neurosci. 2013 Apr; 16(4): 394–406. Published online 2013 Mar 3. doi: 10.1038/nn.3350
PMCID:
PMC3609872
AbstractArticlePDF–3.4M
10.
Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic Mice
Gonzalo Sanchez, Rafael K. Varaschin, Hansruedi Büeler, Paul C. Marcogliese, David S. Park, Louis-Eric Trudeau
PLoS One. 2014; 9(4): e94826. Published online 2014 Apr 14. doi: 10.1371/journal.pone.0094826
PMCID:
PMC3986353
AbstractArticlePDF–1.1M
11.
Neuronal cell type–specific alternative splicing is regulated by the KH domain protein SLM1
Takatoshi Iijima, Yoko Iijima, Harald Witte, Peter Scheiffele
J Cell Biol. 2014 Feb 3; 204(3): 331–342. doi: 10.1083/jcb.201310136
PMCID:
PMC3912522
AbstractArticlePDF–3.2M
12.
A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson’s Research
Marco A. S. Baptista, Kuldip D. Dave, Niketa P. Sheth, Shehan N. De Silva, Kirsten M. Carlson, Yasmin N. Aziz, Brian K. Fiske, Todd B. Sherer, Mark A. Frasier
Dis Model Mech. 2013 Nov; 6(6): 1316–1324. Published online 2013 Sep 12. doi: 10.1242/dmm.011940
PMCID:
PMC3820256
AbstractArticle
13.
The function of orthologues of the human Parkinson’s disease gene LRRK2 across species: implications for disease modeling in preclinical research
Rebekah G. Langston, Iakov N. Rudenko, Mark R. Cookson
Biochem J. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Biochem J. 2016 Feb 1; 473(3): 221–232. doi: 10.1042/BJ20150985
PMCID:
PMC5165698
AbstractArticlePDF–682K
14.
SAM68 regulates neuronal activity-dependent alternative splicing of Neurexin-1
Takatoshi Iijima, Karen Wu, Harald Witte, Yoko Hanno-Iijima, Timo Glatter, Stéphane Richard, Peter Scheiffele
Cell. Author manuscript; available in PMC 2012 Dec 23.
Published in final edited form as: Cell. 2011 Dec 23; 147(7): 1601–1614. doi: 10.1016/j.cell.2011.11.028
PMCID:
PMC3246220
AbstractArticlePDF–6.2M
15.
Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis
Marco Di Fruscio, Taiping Chen, Stéphane Richard
Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6): 2710–2715. doi: 10.1073/pnas.96.6.2710
PMCID:
PMC15834
AbstractArticlePDF–249K
16.
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis
Leslie O. Goodwin, Erik Splinter, Tiffany L. Davis, Rachel Urban, Hao He, Robert E. Braun, Elissa J. Chesler, Vivek Kumar, Max van Min, Juliet Ndukum, Vivek M. Philip, Laura G. Reinholdt, Karen Svenson, Jacqueline K. White, Michael Sasner, Cathleen Lutz, Stephen A. Murray
Genome Res. 2019 Mar; 29(3): 494–505. doi: 10.1101/gr.233866.117
PMCID:
PMC6396414
AbstractArticlePDF–4.8M
17.
Gene and MicroRNA Transcriptome Analysis of Parkinson's Related LRRK2 Mouse Models
Véronique Dorval, Wim Mandemakers, Francis Jolivette, Laetitia Coudert, Rachid Mazroui, Bart De Strooper, Sébastien S. Hébert
PLoS One. 2014; 9(1): e85510. Published online 2014 Jan 10. doi: 10.1371/journal.pone.0085510
PMCID:
PMC3888428
AbstractArticlePDF–1.1M
18.
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain
Adrienne E McKee, Emmanuel Minet, Charlene Stern, Shervin Riahi, Charles D Stiles, Pamela A Silver
BMC Dev Biol. 2005; 5: 14. Published online 2005 Jul 20. doi: 10.1186/1471-213X-5-14
PMCID:
PMC1199591
AbstractArticlePDF–2.0M
19.
Database resources of the National Center for Biotechnology Information
David L. Wheeler, Deanna M. Church, Alex E. Lash, Detlef D. Leipe, Thomas L. Madden, Joan U. Pontius, Gregory D. Schuler, Lynn M. Schriml, Tatiana A. Tatusova, Lukas Wagner, Barbara A. Rapp
Nucleic Acids Res. 2001 Jan 1; 29(1): 11–16. doi: 10.1093/nar/29.1.11
PMCID:
PMC29800
AbstractArticlePDF–101K
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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