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Select item 111002531.

Low expression of ELOVL6 may be involved in fat loss in white adipose tissue of cancer-associated cachexia

Chenyang Jin, Shuangjie Wang, Xiangyu Sui, Qingyang Meng, Guohao Wu

Lipids Health Dis. 2024; 23: 144. Published online 2024 May 17. doi: 10.1186/s12944-024-02126-9

PMCID:: PMC11100253

Abstract Article PDF–4.3M

Select item 105002842.

Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination

Aida V. Garcia Corrales, Sanne G. S. Verberk, Mansour Haidar, Elien Grajchen, Jonas Dehairs, Sam Vanherle, Melanie Loix, Tine Weytjens, Pascal Gervois, Takashi Matsuzaka, Ivo Lambrichts, Johannes V. Swinnen, Jeroen F. J. Bogie, Jerome J. A. Hendriks

Proc Natl Acad Sci U S A. 2023 Sep 12; 120(37): e2301030120. Published online 2023 Sep 5. doi: 10.1073/pnas.2301030120

PMCID:: PMC10500284

Abstract Article PDF–3.4M

Select item 62816803.

Elovl6 regulates mechanical damage-induced keratinocyte death and skin inflammation

Yoshiyuki Nakamura, Takashi Matsuzaka, Satoko Tahara-Hanaoka, Kazuko Shibuya, Hitoshi Shimano, Chigusa Nakahashi-Oda, Akira Shibuya

Cell Death Dis. 2018 Dec; 9(12): 1181. Published online 2018 Dec 5. doi: 10.1038/s41419-018-1226-1

PMCID:: PMC6281680

Abstract Article PDF–1.0M

Select item 42424524.

Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance

Young-Ah Moon, Courtney R. Ochoa, Matthew A. Mitsche, Robert E. Hammer, Jay D. Horton

J Lipid Res. 2014 Dec; 55(12): 2597–2605. doi: 10.1194/jlr.M054353

PMCID:: PMC4242452

Abstract Article PDF–625K

Select item 1244125.

Deciphering peripheral nerve myelination by using Schwann cell expression profiling

Rakesh Nagarajan, Nam Le, Heather Mahoney, Toshiyuki Araki, Jeffrey Milbrandt

Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13): 8998–9003. doi: 10.1073/pnas.132080999

PMCID:: PMC124412

Abstract Article PDF–348K

Select item 74138776.

Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat

Kathrin Weiss-Hersh, Ada L. Garcia, Tamás Marosvölgyi, Mónika Szklenár, Tamás Decsi, Ralph Rühl

Eur J Nutr. 2020; 59(6): 2759–2769. Published online 2019 Nov 1. doi: 10.1007/s00394-019-02121-2

PMCID:: PMC7413877

Abstract Article PDF–970K

Select item 46649627.

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr^−/− mouse model

Motoko Kuba, Takashi Matsuzaka, Rie Matsumori, Ryo Saito, Naoko Kaga, Hikari Taka, Kei Ikehata, Naduki Okada, Takuya Kikuchi, Hiroshi Ohno, Song-iee Han, Yoshinori Takeuchi, Kazuto Kobayashi, Hitoshi Iwasaki, Shigeru Yatoh, Hiroaki Suzuki, Hirohito Sone, Naoya Yahagi, Yoji Arakawa, Tsutomu Fujimura, Yoshimi Nakagawa, Nobuhiro Yamada, Hitoshi Shimano

Sci Rep. 2015; 5: 17604. Published online 2015 Dec 1. doi: 10.1038/srep17604

PMCID:: PMC4664962

Abstract Article PDF–1.8M

Select item 46880358.

Brown Adipose Tissue Thermogenic Capacity Is Regulated by Elovl6

Chong Yew Tan, Samuel Virtue, Guillaume Bidault, Martin Dale, Rachel Hagen, Julian L. Griffin, Antonio Vidal-Puig

Cell Rep. 2015 Dec 15; 13(10): 2039–2047. Published online 2015 Nov 25. doi: 10.1016/j.celrep.2015.11.004

PMCID:: PMC4688035

Abstract Article

Select item 49650819.

Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice

Manami Kikuchi, Masako Shimada, Takashi Matsuzaka, Kiyoaki Ishii, Yoshimi Nakagawa, Misa Takayanagi, Nobuhiro Yamada, Hitoshi Shimano

PLoS One. 2016; 11(7): e0159375. Published online 2016 Jul 28. doi: 10.1371/journal.pone.0159375

PMCID:: PMC4965081

Abstract Article PDF–10M

Select item 370013410.

Impaired Epidermal Permeability Barrier in Mice Lacking Elovl1, the Gene Responsible for Very-Long-Chain Fatty Acid Production

Takayuki Sassa, Yusuke Ohno, Shotaro Suzuki, Toshifumi Nomura, Chieko Nishioka, Toshiki Kashiwagi, Taisuke Hirayama, Masashi Akiyama, Ryo Taguchi, Hiroshi Shimizu, Shigeyoshi Itohara, Akio Kihara

Mol Cell Biol. 2013 Jul; 33(14): 2787–2796. doi: 10.1128/MCB.00192-13

PMCID:: PMC3700134

Abstract Article PDF–2.0M

Select item 55332311.

Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling

Lorin E. Olson, Jie Zhang, Havilah Taylor, David W. Rose, Michael G. Rosenfeld

Proc Natl Acad Sci U S A. 2005 Mar 8; 102(10): 3708–3713. Published online 2005 Feb 22. doi: 10.1073/pnas.0500519102

PMCID:: PMC553323

Abstract Article PDF–510K

Select item 288828112.

ATP-Citrate Lyase Deficiency in the Mouse

Anne P. Beigneux, Cynthia Kosinski, Bryant Gavino, Jay D. Horton, William C. Skarnes, Stephen G. Young

J Biol Chem. Author manuscript; available in PMC 2010 Jun 21.

Published in final edited form as: J Biol Chem. 2004 Mar 5; 279(10): 9557–9564. Published online 2003 Dec 8. doi: 10.1074/jbc.M310512200

PMCID:: PMC2888281

Abstract Article PDF–6.2M

Select item 1014690013.

ZFP750 affects the cutaneous barrier through regulating lipid metabolism

Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli, Lorenzo D’Ambrosio, Laura Falasca, Roberta Nardacci, Lu Wang, Mauro Piacentini, Richard A. Knight, Wei Jia, Qiang Sun, Yufang Shi, Ying Wang, Eleonora Candi, Gerry Melino

Sci Adv. 2023 Apr; 9(17): eadg5423. Published online 2023 Apr 28. doi: 10.1126/sciadv.adg5423

PMCID:: PMC10146900

Abstract Article PDF–2.3M

Select item 795976714.

HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation

Miriam A. Holzman, Abigail Ryckman, Tova M. Finkelstein, Kim Landry-Truchon, Kyra A. Schindler, Jenna M. Bergmann, Lucie Jeannotte, Jennifer H. Mansfield

Front Cell Dev Biol. 2021; 9: 632303. Published online 2021 Feb 25. doi: 10.3389/fcell.2021.632303

PMCID:: PMC7959767

Abstract Article PDF–12M

Select item 504520015.

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa

PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355

PMCID:: PMC5045200

Abstract Article PDF–2.9M

Select item 586818116.

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Jin Li, Su-Ping Deng, Gang Wei, Peng Yu

Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012

PMCID:: PMC5868181

Abstract Article PDF–653K

Select item 381794617.

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates

Jeremy A. Miller, Jason Nathanson, Daniel Franjic, Sungbo Shim, Rachel A. Dalley, Sheila Shapouri, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, Jeffrey L. Bennett, Chang-Kyu Lee, Michael J. Hawrylycz, Allan R. Jones, David G. Amaral, Nenad Sestan, Fred H. Gage, Ed S. Lein

Development. 2013 Nov 15; 140(22): 4633–4644. doi: 10.1242/dev.097212

PMCID:: PMC3817946

Abstract Article

Select item 831323918.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 18788519.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100