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Select item 101923531.

Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis

Seher Yuksel, Bogale Aredo, Yeshumenesh Zegeye, Cynthia X. Zhao, Miao Tang, Xiaohong Li, John D. Hulleman, Laurent Gautron, Sara Ludwig, Eva M. Y. Moresco, Igor A. Butovich, Bruce A. Beutler, Rafael L. Ufret-Vincenty

Commun Biol. 2023; 6: 533. Published online 2023 May 17. doi: 10.1038/s42003-023-04870-7

PMCID:: PMC10192353

Abstract Article PDF–11M

Select item 90266192.

Hormone-sensitive lipase is localized at synapses and is necessary for normal memory functioning in mice

Cecilia Skoug, Cecilia Holm, João M.N. Duarte

J Lipid Res. 2022 May; 63(5): 100195. Published online 2022 Mar 15. doi: 10.1016/j.jlr.2022.100195

PMCID:: PMC9026619

Abstract Article PDF–3.7M

Select item 79469393.

Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase

Laura Pajed, Ulrike Taschler, Anna Tilp, Peter Hofer, Petra Kotzbeck, Stephanie Kolleritsch, Franz P. W. Radner, Isabella Pototschnig, Carina Wagner, Margarita Schratter, Sandra Eder, Sabrina Huetter, Renate Schreiber, Guenter Haemmerle, Thomas O. Eichmann, Martina Schweiger, Gerald Hoefler, Erin E. Kershaw, Achim Lass, Gabriele Schoiswohl

Commun Biol. 2021; 4: 323. Published online 2021 Mar 10. doi: 10.1038/s42003-021-01858-z

PMCID:: PMC7946939

Abstract Article PDF–3.7M

Select item 60819064.

Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice

Mu Xu, Hui-Hua Chang, Xiaoman Jung, Aune Moro, Caroline Ei Ne Chou, Jonathan King, O. Joe Hines, James Sinnett-Smith, Enrique Rozengurt, Guido Eibl

BMC Cancer. 2018; 18: 797. Published online 2018 Aug 7. doi: 10.1186/s12885-018-4713-y

PMCID:: PMC6081906

Abstract Article PDF–2.2M

Select item 51488025.

Hormone-sensitive lipase deficiency alters gene expression and cholesterol content of mouse testis

Feng Wang, Zheng Chen, Xiaofang Ren, Ye Tian, Fucheng Wang, Chao Liu, Pengcheng Jin, Zongyue Li, Feixiong Zhang, Baochang Zhu

Reproduction. 2016 Dec; 153(2): 175–185. Published online 2016 Dec 5. doi: 10.1530/REP-16-0484

PMCID:: PMC5148802

Abstract Article PDF–2.4M

Select item 34590566.

Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice

Sascha Obrowsky, Prakash G. Chandak, Jay V. Patankar, Thomas Pfeifer, Silvia Povoden, Renate Schreiber, Guenter Haemmerle, Sanja Levak-Frank, Dagmar Kratky

Biochim Biophys Acta. 2012 Nov; 1821(11): 1406–1414. doi: 10.1016/j.bbalip.2012.07.013

PMCID:: PMC3459056

Abstract Article

Select item 31363467.

Hormone-sensitive lipase-knockout mice maintain high bone density during aging

Wen-Jun Shen, Li-Fen Liu, Shailja Patel, Fredric B. Kraemer

FASEB J. 2011 Aug; 25(8): 2722–2730. doi: 10.1096/fj.11-181016

PMCID:: PMC3136346

Abstract Article

Select item 31268178.

Altered Desaturation and Elongation of Fatty Acids in Hormone-Sensitive Lipase Null Mice

Céline Fernandez, Kai Schuhmann, Ronny Herzog, Barbara Fielding, Keith Frayn, Andrej Shevchenko, Peter James, Cecilia Holm, Kristoffer Ström

PLoS One. 2011; 6(6): e21603. Published online 2011 Jun 29. doi: 10.1371/journal.pone.0021603

PMCID:: PMC3126817

Abstract Article PDF–834K

Select item 27972809.

Spatiotemporal Regulation of Early Lipolytic Signaling in Adipocytes

Sally Martin, Satomi Okano, Carol Kistler, Manuel A. Fernandez-Rojo, Michelle M. Hill, Robert G. Parton

J Biol Chem. 2009 Nov 13; 284(46): 32097–32107. Published online 2009 Sep 15. doi: 10.1074/jbc.M109.002675

PMCID:: PMC2797280

Abstract Article PDF–5.8M

Select item 225841910.

Attainment of Brown Adipocyte Features in White Adipocytes of Hormone-Sensitive Lipase Null Mice

Kristoffer Ström, Ola Hansson, Stéphanie Lucas, Pernilla Nevsten, Céline Fernandez, Cecilia Klint, Sofia Movérare-Skrtic, Frank Sundler, Claes Ohlsson, Cecilia Holm

PLoS One. 2008; 3(3): e1793. Published online 2008 Mar 12. doi: 10.1371/journal.pone.0001793

PMCID:: PMC2258419

Abstract Article PDF–1.0M

Select item 1540911.

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

Jun-ichi Osuga, Shun Ishibashi, Teruaki Oka, Hiroaki Yagyu, Ryuichi Tozawa, Akihisa Fujimoto, Futoshi Shionoiri, Naoya Yahagi, Frederic B. Kraemer, Osamu Tsutsumi, Nobuhiro Yamada

Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2): 787–792. doi: 10.1073/pnas.97.2.787

PMCID:: PMC15409

Abstract Article PDF–339K

Select item 1070085812.

Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity

Liujun Chen, Lisha Li, Donghong Cui, Yiheng Huang, Haibin Tong, Haleh Zabihi, Shuxia Wang, Yadan Qi, Ted Lakowski, Lin Leng, Suixin Liu, Hong Wu, Lawrence H. Young, Richard Bucala, Dake Qi

Mol Metab. 2024 Jan; 79: 101834. Published online 2023 Nov 5. doi: 10.1016/j.molmet.2023.101834

PMCID:: PMC10700858

Abstract Article PDF–3.3M

Select item 850898513.

Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth

Katharina B. Kuentzel, Ivan Bradić, Alena Akhmetshina, Melanie Korbelius, Silvia Rainer, Dagmar Kolb, Martin Gauster, Nemanja Vujić, Dagmar Kratky

Int J Mol Sci. 2021 Oct; 22(19): 10416. Published online 2021 Sep 27. doi: 10.3390/ijms221910416

PMCID:: PMC8508985

Abstract Article PDF–7.3M

Select item 790301314.

Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

Cecilie Hundahl, Petra Kotzbeck, Hayley B. Burm, Søren H. Christiansen, Lola Torz, Aske W. Helge, Martin P. Madsen, Cecilia Ratner, Annette K. Serup, Jonatan J. Thompson, Thomas O. Eichmann, Tune H. Pers, David P.D. Woldbye, Daniele Piomelli, Bente Kiens, Rudolf Zechner, Louise J. Skov, Birgitte Holst

Mol Metab. 2021 May; 47: 101174. Published online 2021 Feb 5. doi: 10.1016/j.molmet.2021.101174

PMCID:: PMC7903013

Abstract Article PDF–2.9M

Select item 781282115.

Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides

Kristyna Brejchova, Franz Peter Walter Radner, Laurence Balas, Veronika Paluchova, Tomas Cajka, Hana Chodounska, Eva Kudova, Margarita Schratter, Renate Schreiber, Thierry Durand, Rudolf Zechner, Ondrej Kuda

Proc Natl Acad Sci U S A. 2021 Jan 12; 118(2): e2020999118. Published online 2020 Dec 28. doi: 10.1073/pnas.2020999118

PMCID:: PMC7812821

Abstract Article PDF–2.1M

Select item 641565016.

Cardiac overexpression of perilipin 2 induces dynamic steatosis: prevention by hormone-sensitive lipase

Masami Ueno, Jinya Suzuki, Masamichi Hirose, Satsuki Sato, Michiko Imagawa, Yasuo Zenimaru, Sadao Takahashi, Shoichiro Ikuyama, Tsutomu Koizumi, Tadashi Konoshita, Fredric B. Kraemer, Tamotsu Ishizuka

Am J Physiol Endocrinol Metab. 2017 Dec 1; 313(6): E699–E709. Published online 2017 Aug 29. doi: 10.1152/ajpendo.00098.2017

PMCID:: PMC6415650

Abstract Article

Select item 574126617.

Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice

Bo Xia, Guo He Cai, Hao Yang, Shu Pei Wang, Grant A. Mitchell, Jiang Wei Wu

PLoS Genet. 2017 Dec; 13(12): e1007110. Published online 2017 Dec 12. doi: 10.1371/journal.pgen.1007110

PMCID:: PMC5741266

Abstract Article PDF–15M

Select item 543219218.

Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice

Jiang Wei Wu, Christoph Preuss, Shu Pei Wang, Hao Yang, Bo Ji, Gregory W. Carter, Rebecca Gladdy, Gregor Andelfinger, Grant A. Mitchell

PLoS Genet. 2017 May; 13(5): e1006716. Published online 2017 May 1. doi: 10.1371/journal.pgen.1006716

PMCID:: PMC5432192

Abstract Article PDF–17M

Select item 476821619.

SF-1 (NR5A1) expression is stimulated by the PKA pathway and is essential for the PKA-induced activation of LIPE expression in Y-1 cells

K. Kulcenty, M. Holysz, W. H. Trzeciak

Mol Cell Biochem. 2015; 408: 139–145. Published online 2015 Jun 30. doi: 10.1007/s11010-015-2489-9

PMCID:: PMC4768216

Abstract Article PDF–559K

Select item 456237020.

Active autophagy but not lipophagy in macrophages with defective lipolysis

Madeleine Goeritzer, Nemanja Vujic, Stefanie Schlager, Prakash G. Chandak, Melanie Korbelius, Benjamin Gottschalk, Christina Leopold, Sascha Obrowsky, Silvia Rainer, Prakash Doddapattar, Elma Aflaki, Martin Wegscheider, Vinay Sachdev, Wolfgang F. Graier, Dagmar Kolb, Branislav Radovic, Dagmar Kratky

Biochim Biophys Acta. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Oct; 1851(10): 1304–1316. Published online 2015 Jul 2. doi: 10.1016/j.bbalip.2015.06.005

PMCID:: PMC4562370

Abstract Article PDF–6.4M

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