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Select item 97510331.

Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment

Máté Kiss, Els Lebegge, Aleksandar Murgaski, Helena Van Damme, Daliya Kancheva, Jan Brughmans, Isabelle Scheyltjens, Ali Talebi, Robin Maximilian Awad, Yvon Elkrim, Pauline M. R. Bardet, Sana M. Arnouk, Cleo Goyvaerts, Johan Swinnen, Frank Aboubakar Nana, Jo A. Van Ginderachter, Damya Laoui

Front Immunol. 2022; 13: 1003975. Published online 2022 Dec 1. doi: 10.3389/fimmu.2022.1003975

PMCID:: PMC9751033

Abstract Article PDF–5.5M

Select item 94625012.

Junctional adhesion molecule-A deletion increases phagocytosis and improves survival in a murine model of sepsis

Nathan J. Klingensmith, Katherine T. Fay, David A. Swift, Julia M.R. Bazzano, John D. Lyons, Ching-wen Chen, Mei Meng, Kimberly M. Ramonell, Zhe Liang, Eileen M. Burd, Charles A. Parkos, Mandy L. Ford, Craig M. Coopersmith

JCI Insight. 2022 Aug 22; 7(16): e156255. Published online 2022 Aug 22. doi: 10.1172/jci.insight.156255

PMCID:: PMC9462501

Abstract Article PDF–1.2M

Select item 91145183.

JAM-A signals through the Hippo pathway to regulate intestinal epithelial proliferation

Shuling Fan, Michelle Sydney Smith, Justin Keeney, Monique N. O’Leary, Asma Nusrat, Charles A. Parkos

iScience. 2022 May 20; 25(5): 104316. Published online 2022 Apr 27. doi: 10.1016/j.isci.2022.104316

PMCID:: PMC9114518

Abstract Article PDF–3.8M

Select item 78311974.

Western diet-induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis

Biki Gupta, Yunshan Liu, Daniel M. Chopyk, Ravi P. Rai, Chirayu Desai, Pradeep Kumar, Alton B. Farris, Asma Nusrat, Charles A. Parkos, Frank A. Anania, Reben Raeman

FASEB J. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: FASEB J. 2020 May; 34(5): 7089–7102. Published online 2020 Apr 10. doi: 10.1096/fj.201902687R

PMCID:: PMC7831197

Abstract Article PDF–3.3M

Select item 75082795.

JAM-A Acts via C/EBP-α to Promote Claudin-5 Expression and Enhance Endothelial Barrier Function

Nikolaos Kakogiannos, Laura Ferrari, Costanza Giampietro, Anna Agata Scalise, Claudio Maderna, Micol Ravà, Andrea Taddei, Maria Grazia Lampugnani, Federica Pisati, Matteo Malinverno, Emanuele Martini, Ilaria Costa, Michela Lupia, Ugo Cavallaro, Galina V. Beznoussenko, Alexander A. Mironov, Bethania Fernandes, Noemi Rudini, Elisabetta Dejana, Monica Giannotta

Circ Res. 2020 Sep 25; 127(8): 1056–1073. Published online 2020 Jul 15. doi: 10.1161/CIRCRESAHA.120.316742

PMCID:: PMC7508279

Abstract Article PDF–12M

Select item 65438246.

Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice

Anny-Claude Luissint, Holly C. Williams, Wooki Kim, Sven Flemming, Veronica Azcutia, Roland S. Hilgarth, Monique N. O’ Leary, Timothy L. Denning, Asma Nusrat, Charles A. Parkos

Mucosal Immunol. Author manuscript; available in PMC 2019 May 31.

Published in final edited form as: Mucosal Immunol. 2019 May; 12(3): 668–678. Published online 2019 Feb 11. doi: 10.1038/s41385-019-0143-7

PMCID:: PMC6543824

Abstract Article PDF–1.3M

Select item 62831347.

Junctional adhesion molecule A: expression in the murine epididymal tract and accessory organs and acquisition by maturing sperm

Kathie Z. Wu, Kun Li, Deni S. Galileo, Patricia A. Martin-DeLeon

Mol Hum Reprod. 2017 Feb; 23(2): 132–140. Published online 2017 Jan 10. doi: 10.1093/molehr/gaw082

PMCID:: PMC6283134

Abstract Article PDF–733K

Select item 62374418.

Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model

Sven Flemming, Anny-Claude Luissint, Asma Nusrat, Charles A. Parkos

JCI Insight. 2018 Oct 18; 3(20): e99722. Published online 2018 Oct 18. doi: 10.1172/jci.insight.99722

PMCID:: PMC6237441

Abstract Article PDF–2.1M

Select item 55429009.

Deletion of junctional adhesion molecule A from platelets increases early‐stage neointima formation after wire injury in hyperlipidemic mice

Zhen Zhao, Tanja Vajen, Ela Karshovska, Annemiek Dickhout, Martin M. Schmitt, Remco T.A. Megens, Philipp von Hundelshausen, Thomas A. Koeppel, Tilman M. Hackeng, Christian Weber, Rory R. Koenen

J Cell Mol Med. 2017 Aug; 21(8): 1523–1531. Published online 2017 Feb 17. doi: 10.1111/jcmm.13083

PMCID:: PMC5542900

Abstract Article PDF–770K

Select item 503703510.

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

Khalidur Rahman, Chirayu Desai, Smita S. Iyer, Natalie E. Thorn, Pradeep Kumar, Yunshan Liu, Tekla Smith, Andrew S. Neish, Hongliang Li, Shiyun Tan, Pengbo Wu, Xiaoxiong Liu, Yuanjie Yu, Alton B. Farris, Asma Nusrat, Charles A. Parkos, Frank A. Anania

Gastroenterology. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Gastroenterology. 2016 Oct; 151(4): 733–746.e12. Published online 2016 Jun 21. doi: 10.1053/j.gastro.2016.06.022

PMCID:: PMC5037035

Abstract Article PDF–1.3M

Select item 482777011.

A comparative molecular force spectroscopy study of homophilic JAM-A interactions and JAM-A interactions with reovirus attachment protein σ1

Sri Ram Krishna Vedula, Tong Seng Lim, Eva Kirchner, Kristen M. Guglielmi, Terence S. Dermody, Thilo Stehle, Walter Hunziker, Chwee Teck Lim

J Mol Recognit. Author manuscript; available in PMC 2016 Apr 11.

Published in final edited form as: J Mol Recognit. 2008 Jul-Aug; 21(4): 210–216. doi: 10.1002/jmr.886

PMCID:: PMC4827770

Abstract Article PDF–689K

Select item 435137512.

Endothelial JAM-A Promotes Reovirus Viremia and Bloodstream Dissemination

Caroline M. Lai, Karl W. Boehme, Andrea J. Pruijssers, Vrajesh V. Parekh, Luc Van Kaer, Charles A. Parkos, Terence S. Dermody

J Infect Dis. 2015 Feb 1; 211(3): 383–393. Published online 2014 Aug 22. doi: 10.1093/infdis/jiu476

PMCID:: PMC4351375

Abstract Article PDF–766K

Select item 433869813.

Anti‐Inflammatory Peptides From Cardiac Progenitors Ameliorate Dysfunction After Myocardial Infarction

Mei‐Lan Liu, Toshio Nagai, Masakuni Tokunaga, Koji Iwanaga, Katsuhisa Matsuura, Toshinao Takahashi, Masato Kanda, Naomichi Kondo, Atsuhiko T. Naito, Issei Komuro, Yoshio Kobayashi

J Am Heart Assoc. 2014 Dec; 3(6): e001101. Published online 2014 Dec 2. doi: 10.1161/JAHA.114.001101

PMCID:: PMC4338698

Abstract Article PDF–6.4M

Select item 389971814.

High throughput flow cytometry screening reveals a novel role for JAM-A as a cancer stem cell maintenance factor

Justin D. Lathia, Meizhang Li, Maksim Sinyuk, Alvaro G. Alvarado, William A. Flavahan, Kevin Stoltz, Ann Mari Rosager, James Hale, Masahiro Hitomi, Joseph Gallagher, Qiulian Wu, Jody Martin, Jason G. Vidal, Ichiro Nakano, Rikke H. Dahlrot, Steinbjørn Hansen, Roger E. McLendon, Andrew E. Sloan, Shideng Bao, Anita B. Hjelmeland, Christian T. Carson, Ulhas P. Naik, Bjarne Kristensen, Jeremy N. Rich

Cell Rep. Author manuscript; available in PMC 2015 Jan 16.

Published in final edited form as: Cell Rep. 2014 Jan 16; 6(1): 117–129. Published online 2013 Dec 27. doi: 10.1016/j.celrep.2013.11.043

PMCID:: PMC3899718

Abstract Article PDF–4.8M

Select item 364850415.

Junctional Adhesion Molecule-A Regulates Vascular Endothelial Growth Factor Receptor-2 Signaling-Dependent Mouse Corneal Wound Healing

Sharmila Chatterjee, Yan Wang, Melinda K. Duncan, Ulhas P. Naik

PLoS One. 2013; 8(5): e63674. Published online 2013 May 8. doi: 10.1371/journal.pone.0063674

PMCID:: PMC3648504

Abstract Article PDF–1.0M

Select item 351768216.

Effects of JAM-A deficiency or blocking antibodies on neutrophil migration and lung injury in a murine model of ALI

Sowmya P. Lakshmi, Aravind T. Reddy, Meghna U. Naik, Ulhas P. Naik, Raju C. Reddy

Am J Physiol Lung Cell Mol Physiol. 2012 Nov 1; 303(9): L758–L766. Published online 2012 Aug 17. doi: 10.1152/ajplung.00107.2012

PMCID:: PMC3517682

Abstract Article

Select item 342200917.

Relocalization of Junctional Adhesion Molecule A during Inflammatory Stimulation of Brain Endothelial Cells

Svetlana M. Stamatovic, Nikola Sladojevic, Richard F. Keep, Anuska V. Andjelkovic

Mol Cell Biol. 2012 Sep; 32(17): 3414–3427. doi: 10.1128/MCB.06678-11

PMCID:: PMC3422009

Abstract Article PDF–2.9M

Select item 332186118.

JAM-A protects from thrombosis by suppressing integrin α_IIbβ₃-dependent outside-in signaling in platelets

Meghna U. Naik, Timothy J. Stalker, Lawrence F. Brass, Ulhas P. Naik

Blood. 2012 Apr 5; 119(14): 3352–3360. Prepublished online 2012 Jan 23. doi: 10.1182/blood-2011-12-397398

PMCID:: PMC3321861

Abstract Article

Select item 307724419.

JAM-A regulates epithelial proliferation through Akt/β-catenin signalling

Porfirio Nava, Christopher T Capaldo, Stefan Koch, Keli Kolegraff, Carl Robert Rankin, Attila E Farkas, Mattie E Feasel, Linheng Li, Caroline Addis, Charles A Parkos, Asma Nusrat

EMBO Rep. 2011 Apr 1; 12(4): 314–320. Published online 2011 Mar 4. doi: 10.1038/embor.2011.16

PMCID:: PMC3077244

Abstract Article PDF–990K

Select item 283705020.

JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain

Sandra Stelzer, Klaus Ebnet, Jens C Schwamborn

BMC Neurosci. 2010; 11: 27. Published online 2010 Feb 26. doi: 10.1186/1471-2202-11-27

PMCID:: PMC2837050

Abstract Article PDF–1.7M

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