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Select item 108774061.

β-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice

Nina Suda, Alberto Bartolomé, Jiani Liang, Jinsook Son, Yoko Yagishita, Christian Siebel, Domenico Accili, Hongxu Ding, Utpal B. Pajvani

Mol Metab. 2024 Mar; 81: 101894. Published online 2024 Feb 3. doi: 10.1016/j.molmet.2024.101894

PMCID:: PMC10877406

Abstract Article PDF–1.4M

Select item 105633912.

Jagged-1 Reduces Th2 Inflammation and Memory Cell Expansion in Allergic Airway Disease

Soichiro Kimura, Zadia Dupee, Felipe Lima, Ronald Allen, Soha Kazmi, Nickolas Diodati, Nicholas W. Lukacs, Steven L. Kunkel, Matthew Schaller

Immunohorizons. 2023 Feb 1; 7(2): 168–176. Published online 2023 Feb 2. doi: 10.4049/immunohorizons.2300001

PMCID:: PMC10563391

Abstract Article PDF–1.6M

Select item 97280573.

Sex differences and risk factors for bleeding in Alagille syndrome

Simona Hankeova, Noemi Van Hul, Jakub Laznovsky, Elisabeth Verboven, Katrin Mangold, Naomi Hensens, Csaba Adori, Elvira Verhoef, Tomas Zikmund, Feven Dawit, Michaela Kavkova, Jakub Salplachta, Marika Sjöqvist, Bengt R Johansson, Mohamed G Hassan, Linda Fredriksson, Karsten Baumgärtel, Vitezslav Bryja, Urban Lendahl, Andrew Jheon, Florian Alten, Kristina Teär Fahnehjelm, Björn Fischler, Jozef Kaiser, Emma R Andersson

EMBO Mol Med. 2022 Dec; 14(12): e15809. Published online 2022 Nov 8. doi: 10.15252/emmm.202215809

PMCID:: PMC9728057

Abstract Article PDF–12M

Select item 79099534.

DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

Simona Hankeova, Jakub Salplachta, Tomas Zikmund, Michaela Kavkova, Noémi Van Hul, Adam Brinek, Veronika Smekalova, Jakub Laznovsky, Feven Dawit, Josef Jaros, Vítězslav Bryja, Urban Lendahl, Ewa Ellis, Antal Nemeth, Björn Fischler, Edouard Hannezo, Jozef Kaiser, Emma Rachel Andersson

eLife. 2021; 10: e60916. Published online 2021 Feb 26. doi: 10.7554/eLife.60916

PMCID:: PMC7909953

Abstract Article PDF–8.8M

Select item 68500015.

Activation of Notch Signaling by Oocytes and Jag1 in Mouse Ovarian Granulosa Cells

Nisan Hubbard, Rexxi D Prasasya, Kelly E Mayo

Endocrinology. 2019 Dec; 160(12): 2863–2876. Published online 2019 Oct 14. doi: 10.1210/en.2019-00564

PMCID:: PMC6850001

Abstract Article

Select item 63289896.

Jagged1‐expressing adenovirus‐infected dendritic cells induce expansion of Foxp3⁺ regulatory T cells and alleviate T helper type 2‐mediated allergic asthma in mice

Chu‐Lun Lin, Huei‐Mei Huang, Chia‐Ling Hsieh, Chia‐Kwung Fan, Yueh‐Lun Lee

Immunology. 2019 Feb; 156(2): 199–212. Published online 2018 Nov 29. doi: 10.1111/imm.13021

PMCID:: PMC6328989

Abstract Article PDF–1.2M

Select item 55784737.

Jagged1 expression by osteoblast-lineage cells regulates trabecular bone mass and periosteal expansion in mice

D.W. Youngstrom, M.I. Dishowitz, C.B. Bales, E. Carr, P.L. Mutyaba, K.M. Kozloff, H. Shitaye, K.D. Hankenson, K.M. Loomes

Bone. Author manuscript; available in PMC 2017 Aug 31.

Published in final edited form as: Bone. 2016 Oct; 91: 64–74. Published online 2016 Jul 12. doi: 10.1016/j.bone.2016.07.006

PMCID:: PMC5578473

Abstract Article PDF–2.9M

Select item 55527588.

Jagged1 Is Altered in Alzheimer's Disease and Regulates Spatial Memory Processing

Swananda Marathe, Muriel Jaquet, Jean-Marie Annoni, Lavinia Alberi

Front Cell Neurosci. 2017; 11: 220. Published online 2017 Aug 9. doi: 10.3389/fncel.2017.00220

PMCID:: PMC5552758

Abstract Article PDF–2.1M

Select item 54664559.

Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool

Rialnat A Lawal, Xichao Zhu, Kaylind Batey, Corey M Hoffman, Mary A Georger, Freddy Radtke, Matthew J Hilton, Lianping Xing, Benjamin J Frisch, Laura M Calvi

J Bone Miner Res. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: J Bone Miner Res. 2017 Jun; 32(6): 1320–1331. Published online 2017 Mar 9. doi: 10.1002/jbmr.3106

PMCID:: PMC5466455

Abstract Article PDF–2.1M

Select item 469519410.

Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions

Ana-Rita Pedrosa, Alexandre Trindade, Catarina Carvalho, José Graça, Sandra Carvalho, Maria C. Peleteiro, Ralf H. Adams, António Duarte

Oncotarget. 2015 Sep 15; 6(27): 24404–24423. Published online 2015 Jun 8. doi: 10.18632/oncotarget.4380

PMCID:: PMC4695194

Abstract Article PDF–9.1M

Select item 441437011.

Jagged-1 is required for the expansion of CD4⁺ CD25⁺ FoxP3⁺ regulatory T cells and tolerogenic dendritic cells by murine mesenchymal stromal cells

Emer F Cahill, Laura M Tobin, Fiona Carty, Bernard P Mahon, Karen English

Stem Cell Res Ther. 2015; 6(1): 19. Published online 2015 Mar 11. doi: 10.1186/s13287-015-0021-5

PMCID:: PMC4414370

Abstract Article PDF–3.5M

Select item 401792112.

Angiocrine Factors Deployed by Tumor Vascular Niche Induce B-Cell Lymphoma Invasiveness and Chemoresistance

Zhongwei Cao, Bi-Sen Ding, Peipei Guo, Sharrell B. Lee, Jason M. Butler, Stephanie C. Casey, Michael Simons, Wayne Tam, Dean W. Felsher, Koji Shido, Arash Rafii, Joseph M. Scandura, Shahin Rafii

Cancer Cell. Author manuscript; available in PMC 2015 Mar 17.

Published in final edited form as: Cancer Cell. 2014 Mar 17; 25(3): 350–365. doi: 10.1016/j.ccr.2014.02.005

PMCID:: PMC4017921

Abstract Article PDF–2.7M

Select item 318065313.

Low-Dose Lipopolysaccharide Affects Lung Allergic Responses by Regulating Jagged1 Expression on Antigen-Pulsed Dendritic Cells

Masakazu Okamoto, Katsuyuki Takeda, Joseph J. Lucas, Anthony Joetham, Koji Yasutomo, Erwin W. Gelfand

Int Arch Allergy Immunol. 2011 Dec; 157(1): 65–72. Published online 2011 Sep 6. doi: 10.1159/000324836

PMCID:: PMC3180653

Abstract Article PDF–169K

Select item 304041514.

Tumor-derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells

Nilay Sethi, Xudong Dai, Christopher G. Winter, Yibin Kang

Cancer Cell. Author manuscript; available in PMC 2012 Feb 15.

Published in final edited form as: Cancer Cell. 2011 Feb 15; 19(2): 192–205. Published online 2011 Feb 3. doi: 10.1016/j.ccr.2010.12.022

PMCID:: PMC3040415

Abstract Article PDF–3.6M

Select item 201371215.

Genetic Background Modifies Inner Ear and Eye Phenotypes of Jag1 Heterozygous Mice

Amy E. Kiernan, Renhua Li, Norman L. Hawes, Gary A. Churchill, Thomas Gridley

Genetics. 2007 Sep; 177(1): 307–311. doi: 10.1534/genetics.107.075960

PMCID:: PMC2013712

Abstract Article PDF–501K

Select item 176637416.

Regulation of dendritic-cell differentiation by bone marrow stroma via different Notch ligands

Pingyan Cheng, Yulia Nefedova, Cesar A. Corzo, Dmitry I. Gabrilovich

Blood. 2007 Jan 15; 109(2): 507–515. Prepublished online 2006 Sep 14. doi: 10.1182/blood-2006-05-025601

PMCID:: PMC1766374

Abstract Article

Select item 1088495917.

Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins

Hannah L. Sunshine, Andrew C. Cicchetto, Karolina Elżbieta Kaczor-Urbanowicz, Feiyang Ma, Danielle Pi, Chloe Symons, Martin Turner, Vipul Shukla, Heather R. Christofk, Thomas A. Vallim, M. Luisa Iruela-Arispe

Cell Rep. Author manuscript; available in PMC 2024 Feb 23.

Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113627. Published online 2023 Dec 28. doi: 10.1016/j.celrep.2023.113627

PMCID:: PMC10884959

Abstract Article PDF–4.0M

Select item 900455218.

Cyclin B2 overexpression promotes tumour growth by regulating jagged 1 in hepatocellular carcinoma

Yening Xiao, Jiamei Ma, Chunliu Guo, Danni Liu, Jing Pan, Xiaoxi Huang

Aging (Albany NY) 2022 Mar 31; 14(6): 2855–2867. Published online 2022 Mar 29. doi: 10.18632/aging.203979

PMCID:: PMC9004552

Abstract Article PDF–1.3M

Select item 845329119.

Decreased Jagged1 expression in vascular smooth muscle cells delays endothelial regeneration in arteriovenous graft

Qunying Guo, Fengzhang Huang, Ying Qing, Shaozhen Feng, Xiaoguang Xiao, Yun Wang, Ming Liang, Tao Wang, William E Mitch, Jizhong Cheng

Cardiovasc Res. 2020 Nov 1; 116(13): 2142–2155. Published online 2020 Jan 8. doi: 10.1093/cvr/cvz333

PMCID:: PMC8453291

Abstract Article PDF–1.5M

Select item 777325120.

Jagged1 intracellular domain modulates steroidogenesis in testicular Leydig cells

Sudeep Kumar, Hee-Sae Park, Keesook Lee

PLoS One. 2020; 15(12): e0244553. Published online 2020 Dec 30. doi: 10.1371/journal.pone.0244553

PMCID:: PMC7773251

Abstract Article PDF–1.2M

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