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Select item 71445241.

Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

Carsten Deppermann, Rachel M. Kratofil, Moritz Peiseler, Bruna A. David, Joel Zindel, Fernanda Vargas E Silva Castanheira, Fardau van der Wal, Agostina Carestia, Craig N. Jenne, Jamey D. Marth, Paul Kubes

J Exp Med. 2020 Apr 6; 217(4): e20190723. Published online 2020 Jan 24. doi: 10.1084/jem.20190723

PMCID:: PMC7144524

Abstract Article PDF–6.2M

Select item 53338412.

Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis

Katrin Echtler, Ildiko Konrad, Michael Lorenz, Simon Schneider, Sebastian Hofmaier, Florian Plenagl, Konstantin Stark, Thomas Czermak, Anca Tirniceriu, Martin Eichhorn, Axel Walch, Georg Enders, Steffen Massberg, Christian Schulz

PLoS One. 2017; 12(3): e0172788. Published online 2017 Mar 2. doi: 10.1371/journal.pone.0172788

PMCID:: PMC5333841

Abstract Article PDF–1.6M

Select item 49725753.

Nucleation of platelets with bloodborne pathogens on Kupffer cell precedes other innate immunity and contributes to bacterial clearance

Connie H. Y. Wong, Craig N. Jenne, Björn Petri, Navina L. Chrobok, Paul Kubes

Nat Immunol. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Nat Immunol. 2013 Aug; 14(8): 785–792. Published online 2013 Jun 16. doi: 10.1038/ni.2631

PMCID:: PMC4972575

Abstract Article PDF–1.5M

Select item 31095354.

CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells

Catherine Robin, Katrin Ottersbach, Jean-Charles Boisset, Aneta Oziemlak, Elaine Dzierzak

Blood. 2011 May 12; 117(19): 5088–5091. Prepublished online 2011 Mar 17. doi: 10.1182/blood-2011-01-329516

PMCID:: PMC3109535

Abstract Article

Select item 26302755.

Species differences in small molecule binding to αIIbβ3 are the result of sequence differences in 2 loops of the αIIb β propeller

Ramesh B. Basani, Hua Zhu, Michael A. Thornton, Cinque S. Soto, William F. DeGrado, M. Anna Kowalska, Joel S. Bennett, Mortimer Poncz

Blood. 2009 Jan 22; 113(4): 902–910. Prepublished online 2008 Nov 5. doi: 10.1182/blood-2008-09-177337

PMCID:: PMC2630275

Abstract Article

Select item 67175666.

CD45 expression discriminates waves of embryonic megakaryocytes in the mouse

Isabel Cortegano, Natalia Serrano, Carolina Ruiz, Mercedes Rodríguez, Carmen Prado, Mario Alía, Andrés Hidalgo, Eva Cano, Belén de Andrés, María-Luisa Gaspar

Haematologica. 2019 Sep; 104(9): 1853–1865. Prepublished online 2018 Dec 20. doi: 10.3324/haematol.2018.192559

PMCID:: PMC6717566

Abstract Article PDF–4.4M

Select item 43627117.

Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level

Gemma Swiers, Claudia Baumann, John O'Rourke, Eleni Giannoulatou, Stephen Taylor, Anagha Joshi, Victoria Moignard, Cristina Pina, Thomas Bee, Konstantinos D. Kokkaliaris, Momoko Yoshimoto, Mervin C. Yoder, Jon Frampton, Timm Schroeder, Tariq Enver, Berthold Göttgens, Marella F.T.R. de Bruijn

Nat Commun. Author manuscript; available in PMC 2015 Mar 17.

Published in final edited form as: Nat Commun. 2013; 4: 2924. doi: 10.1038/ncomms3924

PMCID:: PMC4362711

Abstract Article PDF–3.0M

Select item 37206478.

RhoA Is Essential for Maintaining Normal Megakaryocyte Ploidy and Platelet Generation

Aae Suzuki, Jae-Won Shin, Yuhuan Wang, Sang H. Min, Morty Poncz, John K. Choi, Dennis E. Discher, Chris L. Carpenter, Lurong Lian, Liang Zhao, Yangfeng Wang, Charles S. Abrams

PLoS One. 2013; 8(7): e69315. Published online 2013 Jul 23. doi: 10.1371/journal.pone.0069315

PMCID:: PMC3720647

Abstract Article PDF–1.0M

Select item 34308669.

The transcriptional programme controlled by Runx1 during early embryonic blood development

Yosuke Tanaka, Anagha Joshi, Nicola K. Wilson, Sarah Kinston, Shinichi Nishikawa, Berthold Göttgens

Dev Biol. 2012 Jun 15; 366(2): 404–419. doi: 10.1016/j.ydbio.2012.03.024

PMCID:: PMC3430866

Abstract Article

Select item 310070110.

Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling

Cunji Gao, Brian Boylan, Juan Fang, David A. Wilcox, Debra K. Newman, Peter J. Newman

Blood. 2011 May 5; 117(18): 4946–4952. Prepublished online 2011 Mar 2. doi: 10.1182/blood-2010-09-307751

PMCID:: PMC3100701

Abstract Article

Select item 278154211.

Evidence That Integrin αIIbβ3-dependent Interaction of Mast Cells with Fibrinogen Exacerbates Chronic Inflammation

Toshihiko Oki, Koji Eto, Kumi Izawa, Yoshinori Yamanishi, Naoki Inagaki, Jon Frampton, Toshio Kitamura, Jiro Kitaura

J Biol Chem. 2009 Nov 6; 284(45): 31463–31472. Published online 2009 Sep 15. doi: 10.1074/jbc.M109.030213

PMCID:: PMC2781542

Abstract Article PDF–2.1M

Select item 266885312.

Antithrombotic effects of targeting αIIbβ3 signaling in platelets

Ararat J. Ablooglu, Jian Kang, Brian G. Petrich, Mark H. Ginsberg, Sanford J. Shattil

Blood. 2009 Apr 9; 113(15): 3585–3592. Prepublished online 2008 Nov 12. doi: 10.1182/blood-2008-09-180687

PMCID:: PMC2668853

Abstract Article

Select item 146442113.

Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin α_IIbβ₃

Zhenyu Li, Guoying Zhang, Robert Feil, Jiahuai Han, Xiaoping Du

Blood. 2006 Feb 1; 107(3): 965–972. Prepublished online 2005 Oct 6. doi: 10.1182/blood-2005-03-1308

PMCID:: PMC1464421

Abstract Article

Select item 1087968314.

Novel GNE missense variants impair de novo sialylation and cause defective angiogenesis in the developing brain in mice

Lulu Huang, Yuji Kondo, Lijuan Cao, Jingjing Han, Tianyi Li, Bin Zuo, Fei Yang, Yun Li, Zhenni Ma, Xia Bai, Miao Jiang, Changgeng Ruan, Lijun Xia

Blood Adv. 2024 Feb 27; 8(4): 991–1001. Published online 2024 Jan 20. doi: 10.1182/bloodadvances.2023011490

PMCID:: PMC10879683

Abstract Article PDF–4.4M

Select item 986081815.

SHIP1 Controls Internal Platelet Contraction and α_IIbβ₃ Integrin Dynamics in Early Platelet Activation

Sonia Severin, Alessandra Consonni, Gaëtan Chicanne, Sophie Allart, Bernard Payrastre, Marie-Pierre Gratacap

Int J Mol Sci. 2023 Jan; 24(2): 958. Published online 2023 Jan 4. doi: 10.3390/ijms24020958

PMCID:: PMC9860818

Abstract Article PDF–2.6M

Select item 715696916.

Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation

Cristina Porcheri, Ohad Golan, Fernando J Calero‐Nieto, Roshana Thambyrajah, Cristina Ruiz‐Herguido, Xiaonan Wang, Francesca Catto, Yolanda Guillén, Roshani Sinha, Jessica González, Sarah J Kinston, Samanta A Mariani, Antonio Maglitto, Chris S Vink, Elaine Dzierzak, Pierre Charbord, Bertie Göttgens, Lluis Espinosa, David Sprinzak, Anna Bigas

EMBO J. 2020 Apr 15; 39(8): e104270. Published online 2020 Mar 9. doi: 10.15252/embj.2019104270

PMCID:: PMC7156969

Abstract Article PDF–3.3M

Select item 544159717.

SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume

Siying Zou, Alexandra M. Teixeira, Myrto Kostadima, William J. Astle, Aparna Radhakrishnan, Lukas Mikolaj Simon, Lucy Truman, Jennifer S. Fang, John Hwa, Ping-xia Zhang, Pim van der Harst, Paul F. Bray, Willem H. Ouwehand, Mattia Frontini, Diane S. Krause

PLoS One. 2017; 12(5): e0178095. Published online 2017 May 23. doi: 10.1371/journal.pone.0178095

PMCID:: PMC5441597

Abstract Article PDF–4.5M

Select item 485477618.

Dok-1 Negatively Regulates Platelet Integrin αIIbβ3 Outside-in Signaling and Inhibits Thrombosis in Mice

Masaru Niki, Manasa K. Nayak, Hong Jin, Neha Bhasin, Edward F. Plow, Pier Paolo Pandolfi, Paul B. Rothman, Anil K. Chauhan, Steven R. Lentz

Thromb Haemost. Author manuscript; available in PMC 2017 May 2.

Published in final edited form as: Thromb Haemost. 2016 May 2; 115(5): 969–978. Published online 2016 Jan 21. doi: 10.1160/TH15-05-0373

PMCID:: PMC4854776

Abstract Article PDF–2.0M

Select item 458233719.

Fibrin activates GPVI in human and mouse platelets

Osama M. Alshehri, Craig E. Hughes, Samantha Montague, Stephanie K. Watson, Jon Frampton, Markus Bender, Steve P. Watson

Blood. 2015 Sep 24; 126(13): 1601–1608. Prepublished online 2015 Aug 17. doi: 10.1182/blood-2015-04-641654

PMCID:: PMC4582337

Abstract Article

Select item 439647320.

Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage

Issaka Yougbaré, Sean Lang, Hong Yang, Pingguo Chen, Xu Zhao, Wei-She Tai, Darko Zdravic, Brian Vadasz, Conglei Li, Siavash Piran, Alexandra Marshall, Guangheng Zhu, Heidi Tiller, Mette Kjaer Killie, Shelley Boyd, Howard Leong-Poi, Xiao-Yan Wen, Bjorn Skogen, S. Lee Adamson, John Freedman, Heyu Ni

J Clin Invest. 2015 Apr 1; 125(4): 1545–1556. Published online 2015 Mar 16. doi: 10.1172/JCI77820