PMC Links for Gene (Select 16333) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 511

<< First< Prev

Page of 26

Select item 102023921.

β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes

Søs Skovsø, Peter Overby, Jasmine Memar-Zadeh, Jason T C Lee, Jenny C C Yang, Iryna Shanina, Vaibhav Sidarala, Elena Levi-D’Ancona, Jie Zhu, Scott A Soleimanpour, Marc S Horwitz, James D Johnson

Endocrinology. 2022 Nov; 163(11): bqac144. Published online 2022 Sep 1. doi: 10.1210/endocr/bqac144

PMCID:: PMC10202392

Abstract Article

Select item 89833832.

Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress

Carly M. Darden, Srividya Vasu, Jordan Mattke, Yang Liu, Christopher J. Rhodes, Bashoo Naziruddin, Michael C. Lawrence

iScience. 2022 Apr 15; 25(4): 104125. Published online 2022 Mar 19. doi: 10.1016/j.isci.2022.104125

PMCID:: PMC8983383

Abstract Article PDF–5.6M

Select item 86609783.

The Tetracycline-Controlled Transactivator (Tet-On/Off) System in β-Cells Reduces Insulin Expression and Secretion in Mice

Nathalie Jouvet, Khalil Bouyakdan, Scott A. Campbell, Cindy Baldwin, Shannon E. Townsend, Maureen A. Gannon, Vincent Poitout, Thierry Alquier, Jennifer L. Estall

Diabetes. 2021 Dec; 70(12): 2850–2859. Published online 2021 Oct 5. doi: 10.2337/db21-0147

PMCID:: PMC8660978

Abstract Article PDF–4.8M

Select item 71158124.

Development of insulin resistance preceded major changes in iron homeostasis in mice fed a high-fat diet

Joe Varghese, Jithu V James, R Anand, Muthuraman Narayanasamy, Grace Rebekah, Banumathi Ramakrishna, Arun Jose Nellickal, Molly Jacob

J Nutr Biochem. Author manuscript; available in PMC 2020 Jul 23.

Published in final edited form as: J Nutr Biochem. 2020 Jun 2 : 108441. Published online 2020 Jun 2. doi: 10.1016/j.jnutbio.2020.108441

PMCID:: PMC7115812

Abstract Article PDF–2.4M

Select item 64836455.

Epigenetic modulation of β cells by interferon-α via PNPT1/mir-26a/TET2 triggers autoimmune diabetes

Mihaela Stefan-Lifshitz, Esra Karakose, Lingguang Cui, Abora Ettela, Zhengzi Yi, Weijia Zhang, Yaron Tomer

JCI Insight. 2019 Mar 7; 4(5): e126663. Published online 2019 Mar 7. doi: 10.1172/jci.insight.126663

PMCID:: PMC6483645

Abstract Article PDF–8.2M

Select item 60291096.

Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling

Hanwoong Woo, Caroline Jeeyeon Hong, Seonghee Jung, Seongwon Choe, Seong-Woon Yu

Mol Brain. 2018; 11: 37. Published online 2018 Jul 3. doi: 10.1186/s13041-018-0381-8

PMCID:: PMC6029109

Abstract Article PDF–3.7M

Select item 50857917.

Maternal Chromium Restriction Leads to Glucose Metabolism Imbalance in Mice Offspring through Insulin Signaling and Wnt Signaling Pathways

Qian Zhang, Xiaofang Sun, Xinhua Xiao, Jia Zheng, Ming Li, Miao Yu, Fan Ping, Zhixin Wang, Cuijuan Qi, Tong Wang, Xiaojing Wang

Int J Mol Sci. 2016 Oct; 17(10): 1767. Published online 2016 Oct 22. doi: 10.3390/ijms17101767

PMCID:: PMC5085791

Abstract Article PDF–2.3M

Select item 47321988.

O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells

Sean P. Durning, Heather Flanagan-Steet, Nripesh Prasad, Lance Wells

J Biol Chem. 2016 Jan 29; 291(5): 2107–2118. Published online 2015 Nov 23. doi: 10.1074/jbc.M115.693580

PMCID:: PMC4732198

Abstract Article PDF–2.0M

Select item 47255049.

Growth factors and medium hyperglycemia induce Sox9⁺ ductal cell differentiation into β cells in mice with reversal of diabetes

Mingfeng Zhang, Qing Lin, Tong Qi, Tiankun Wang, Ching-Cheng Chen, Arthur D. Riggs, Defu Zeng

Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3): 650–655. Published online 2016 Jan 5. doi: 10.1073/pnas.1524200113

PMCID:: PMC4725504

Abstract Article PDF–1.9M

Select item 377437410.

Differential Contribution of Insulin and Amino Acids to the mTORC1-Autophagy Pathway in the Liver and Muscle

Takako Naito, Akiko Kuma, Noboru Mizushima

J Biol Chem. 2013 Jul 19; 288(29): 21074–21081. Published online 2013 Jun 6. doi: 10.1074/jbc.M113.456228

PMCID:: PMC3774374

Abstract Article PDF–1.6M

Select item 292066311.

Mapping Dynamic Protein Interactions to Insulin Secretory Granule Behavior with TIRF-FRET

Alice D. Lam, Sahar Ismail, Ray Wu, Ofer Yizhar, Daniel R. Passmore, Stephen A. Ernst, Edward L. Stuenkel

Biophys J. 2010 Aug 9; 99(4): 1311–1320. doi: 10.1016/j.bpj.2010.06.014

PMCID:: PMC2920663

Abstract Article PDF–1022K

Select item 282342112.

Proinsulin C-peptide Regulates Ribosomal RNA Expression

Emma Lindahl, Ulrika Nyman, Farasat Zaman, Carina Palmberg, Anna Cascante, Jawed Shafqat, Masaharu Takigawa, Lars Sävendahl, Hans Jörnvall, Bertrand Joseph

J Biol Chem. 2010 Jan 29; 285(5): 3462–3469. Published online 2009 Nov 16. doi: 10.1074/jbc.M109.053587

Correction in:: J Biol Chem. 2017 Mar 10; 292(10): 4382.

PMCID:: PMC2823421

Abstract Article PDF–1.7M

Select item 1110554813.

Caveolar targeting links Kv1.3 with the insulin-dependent adipocyte physiology

Mireia Pérez-Verdaguer, Jesusa Capera, María Ortego-Domínguez, Joanna Bielanska, Núria Comes, Rafael J. Montoro, Marta Camps, Antonio Felipe

Cell Mol Life Sci. 2018 Nov; 75(21): 4059–4075. Published online 2018 Jun 11. doi: 10.1007/s00018-018-2851-7

PMCID:: PMC11105548

Abstract Article PDF–2.2M

Select item 1096192614.

TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet

Sarah M. Graff, Arya Y. Nakhe, Prasanna K. Dadi, Matthew T. Dickerson, Jordyn R. Dobson, Karolina E. Zaborska, Chloe E. Ibsen, Regan B. Butterworth, Nicholas C. Vierra, David A. Jacobson

Cell Rep. Author manuscript; available in PMC 2024 Mar 25.

Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113673. Published online 2024 Jan 10. doi: 10.1016/j.celrep.2024.113673

PMCID:: PMC10961926

Abstract Article PDF–2.0M

Select item 1054274315.

SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells

Hitoshi Iida, Tatsuyoshi Kono, Chih-Chun Lee, Preethi Krishnan, Matthew C. Arvin, Staci A. Weaver, Timothy S. Jarvela, Renato C. S. Branco, Madeline R. McLaughlin, Robert N. Bone, Xin Tong, Peter Arvan, Iris Lindberg, Carmella Evans-Molina

Diabetologia. 2023; 66(11): 2042–2061. Published online 2023 Aug 4. doi: 10.1007/s00125-023-05979-4

PMCID:: PMC10542743

Abstract Article PDF–2.3M

Select item 1033368116.

Pancreatic beta-cell specific BAG3 knockout results in chronic hyperinsulinemia inducing insulin resistance

Verena Damiani, Alessia Lamolinara, Ilaria Cicalini, Maria Concetta Cufaro, Francesco Del Pizzo, Federica Di Marco, Piero Del Boccio, Beatrice Dufrusine, Michael Hahne, Rossano Lattanzio, Damiana Pieragostino, Manuela Iezzi, Massimo Federici, Maria Caterina Turco, Arianna Maiorana, Carlo Dionisi-Vici, Vincenzo De Laurenzi

Mol Metab. 2023 Aug; 74: 101752. Published online 2023 Jun 10. doi: 10.1016/j.molmet.2023.101752

PMCID:: PMC10333681

Abstract Article PDF–4.9M

Select item 988732017.

Bone-marrow derived cells do not contribute to new beta-cells in the inflamed pancreas

Yinan Jiang, John Wiersch, Wei Wu, Jieqi Qian, Maharana Prathap R. Adama, Nannan Wu, Weixia Yang, Congde Chen, Lingyan Zhu, Krishna Prasadan, George K. Gittes, Xiangwei Xiao

Front Immunol. 2023; 14: 1084056. Published online 2023 Jan 17. doi: 10.3389/fimmu.2023.1084056