PMC Links for Gene (Select 161725) - PMC

Select item 59855371.

OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome

Mohammed Uddin, Brianna K. Unda, Vickie Kwan, Nicholas T. Holzapfel, Sean H. White, Leon Chalil, Marc Woodbury-Smith, Karen S. Ho, Erin Harward, Nadeem Murtaza, Biren Dave, Giovanna Pellecchia, Lia D’Abate, Thomas Nalpathamkalam, Sylvia Lamoureux, John Wei, Marsha Speevak, James Stavropoulos, Kristin J. Hope, Brad W. Doble, Jacob Nielsen, E. Robert Wassman, Stephen W. Scherer, Karun K. Singh

Am J Hum Genet. 2018 Feb 1; 102(2): 278–295. Published online 2018 Feb 1. doi: 10.1016/j.ajhg.2018.01.006

PMCID:: PMC5985537

Abstract Article PDF–3.6M

Select item 82929092.

SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth

Siyuan Su, Jianfeng Chen, Yao Jiang, Ying Wang, Tamara Vital, Jiaming Zhang, Christian Laggner, Kong T. Nguyen, Zhichuan Zhu, Alex W. Prevatte, Natalie K. Barker, Laura E. Herring, Ian J. Davis, Pengda Liu

Adv Sci (Weinh) 2021 Jul; 8(14): 2004846. Published online 2021 Jun 1. doi: 10.1002/advs.202004846

PMCID:: PMC8292909

Abstract Article PDF–4.0M

Select item 39904063.

A genome-wide association study for venous thromboembolism: the extended Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

Weihong Tang, Martina Teichert, Daniel I. Chasman, John A. Heit, Pierre-Emmanuel Morange, Guo Li, Nathan Pankratz, Frank W. Leebeek, Guillaume Paré, Mariza de Andrade, Christophe Tzourio, Bruce M. Psaty, Saonli Basu, Rikje Ruiter, Lynda Rose, Sebastian M. Armasu, Thomas Lumley, Susan R. Heckbert, André G. Uitterlinden, Mark Lathrop, Kenneth M. Rice, Mary Cushman, Albert Hofman, Jean-Charles Lambert, Nicole L. Glazer, James S. Pankow, Jacqueline C. Witteman, Philippe Amouyel, Joshua C. Bis, Edwin G. Bovill, Xiaoxiao Kong, Russell P. Tracy, Eric Boerwinkle, Jerome I. Rotter, David-Alexandre Trégouët, Daan W. Loth, Bruno H. Ch. Stricker, Paul M Ridker, Aaron R. Folsom, Nicholas L. Smith

Genet Epidemiol. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Genet Epidemiol. 2013 Jul; 37(5): 512–521. Published online 2013 May 5. doi: 10.1002/gepi.21731

PMCID:: PMC3990406

Abstract Article PDF–441K

Select item 30337654.

Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the CHARGE Consortium

Alanna C. Morrison, Janine F. Felix, L. Adrienne Cupples, Nicole L. Glazer, Laura R. Loehr, Abbas Dehghan, Serkalem Demissie, Joshua C. Bis, Wayne D. Rosamond, Yurii S. Aulchenko, Ying A. Wang, Talin Haritunians, Aaron R. Folsom, Fernando Rivadeneira, Emelia J. Benjamin, Thomas Lumley, David Couper, Bruno H. Stricker, Christopher J. O'Donnell, Kenneth M. Rice, Patricia P. Chang, Albert Hofman, Daniel Levy, Jerome I. Rotter, Ervin R. Fox, Andre G. Uitterlinden, Thomas J. Wang, Bruce M. Psaty, James T. Willerson, Cornelia M. van Duijn, Eric Boerwinkle, Jacqueline C. M. Witteman, Ramachandran S. Vasan, Nicholas L. Smith

Circ Cardiovasc Genet. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2010 Jun 1; 3(3): 248–255. Published online 2010 Apr 17. doi: 10.1161/CIRCGENETICS.109.895995

PMCID:: PMC3033765

Abstract Article PDF–603K

Select item 79198365.

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase

Hyo Jin Kim, Jongchan Kim

Int J Mol Sci. 2021 Feb; 22(4): 1936. Published online 2021 Feb 16. doi: 10.3390/ijms22041936

PMCID:: PMC7919836

Abstract Article PDF–5.0M

Select item 37052086.

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

Tycho E.T. Mevissen, Manuela K. Hospenthal, Paul P. Geurink, Paul R. Elliott, Masato Akutsu, Nadia Arnaudo, Reggy Ekkebus, Yogesh Kulathu, Tobias Wauer, Farid El Oualid, Stefan M.V. Freund, Huib Ovaa, David Komander

Cell. 2013 Jul 3; 154(1): 169–184. doi: 10.1016/j.cell.2013.05.046

PMCID:: PMC3705208

Abstract Article

Select item 69420457.

Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne

Xiao Wu, Shichang Liu, Cari Sagum, Jianji Chen, Rajesh Singh, Apurva Chaturvedi, John R. Horton, Tanuja R. Kashyap, David Fushman, Xiaodong Cheng, Mark T. Bedford, Bin Wang

Genes Dev. 2019 Dec 1; 33(23-24): 1702–1717. doi: 10.1101/gad.332395.119

PMCID:: PMC6942045

Abstract Article PDF–7.6M

Select item 38546698.

Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects

Xutao Deng, Ester C. Sabino, Edecio Cunha-Neto, Antonio L. Ribeiro, Barbara Ianni, Charles Mady, Michael P. Busch, Mark Seielstad, the REDSII Chagas study group from the NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component

PLoS One. 2013; 8(11): e79629. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0079629

PMCID:: PMC3854669

Abstract Article PDF–408K

Select item 58962029.

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Dominika Kwasna, Syed Arif Abdul Rehman, Jayaprakash Natarajan, Stephen Matthews, Ross Madden, Virginia De Cesare, Simone Weidlich, Satpal Virdee, Ivan Ahel, Ian Gibbs-Seymour, Yogesh Kulathu

Mol Cell. 2018 Apr 5; 70(1): 150–164.e6. doi: 10.1016/j.molcel.2018.02.023

PMCID:: PMC5896202

Abstract Article

Select item 1020895810.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 399653711.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 760600812.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Abstract Article PDF–2.5M

Select item 484160713.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 582692614.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011