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Select item 105802941.

IGFBP2 expressing midlobular hepatocytes preferentially contribute to liver homeostasis and regeneration

Yu-Hsuan Lin, Yonglong Wei, Qiyu Zeng, Yunguan Wang, Chase A. Pagani, Lin Li, Min Zhu, Zixi Wang, Meng-Hsiung Hsieh, Natasha Corbitt, Yu Zhang, Tripti Sharma, Tao Wang, Hao Zhu

Cell Stem Cell. Author manuscript; available in PMC 2024 May 4.

Published in final edited form as: Cell Stem Cell. 2023 May 4; 30(5): 665–676.e4. doi: 10.1016/j.stem.2023.04.007

PMCID:: PMC10580294

Abstract Article PDF–2.9M

Select item 70696882.

Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice

Gang Xi, Victoria E Demambro, Susan D’Costa, Shalier K Xia, Zach C Cox, Clifford J Rosen, David R Clemmons

Endocrinology. 2020 Apr; 161(4): bqz007. Published online 2020 Mar 13. doi: 10.1210/endocr/bqz007

PMCID:: PMC7069688

Abstract Article

Select item 68919073.

IGFBP2 Plays an Essential Role in Cognitive Development during Early Life

Shumsuzzaman Khan, Xinjiang Lu, Qingyao Huang, Jiawei Tang, Jian Weng, Zhi Yang, Minchao Lv, Xiaokang Xu, Fangyuan Xia, Mengchen Zhang, Yi Li, Shuangshuang Liu, Gareth Leng, Nicholas Spitzer, Jizeng Du, Xuequn Chen

Adv Sci (Weinh) 2019 Dec; 6(23): 1901152. Published online 2019 Oct 14. doi: 10.1002/advs.201901152

PMCID:: PMC6891907

Abstract Article PDF–6.7M

Select item 51171904.

IGFBP-2 directly stimulates osteoblast differentiation

Gang Xi, Christine Wai, Victoria DeMambro, Clifford J Rosen, David R Clemmons

J Bone Miner Res. Author manuscript; available in PMC 2016 Nov 21.

Published in final edited form as: J Bone Miner Res. 2014 Nov; 29(11): 2427–2438. doi: 10.1002/jbmr.2282

PMCID:: PMC5117190

Abstract Article PDF–1.5M

Select item 49159805.

Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies

Lynette M. Phillips, Xinhui Zhou, David E. Cogdell, Corrine Yingxuan Chua, Anouk Huisinga, Kenneth R. Hess, Gregory N. Fuller, Wei Zhang

J Pathol. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: J Pathol. 2016 Jul; 239(3): 355–364. Published online 2016 Jun 10. doi: 10.1002/path.4734

PMCID:: PMC4915980

Abstract Article PDF–774K

Select item 47172796.

Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD‐deficient IGFBP‐2 variant in female transgenic mice

Andreas Hoeflich, Anja Reyer, Daniela Ohde, Nancy Schindler, Julia Brenmoehl, Marion Spitschak, Martina Langhammer, Armin Tuchscherer, Elisa Wirthgen, Ingrid Renner‐Müller, Rüdiger Wanke, Friedrich Metzger, Maximilian Bielohuby, Eckhard Wolf

Aging Cell. 2016 Feb; 15(1): 111–117. Published online 2015 Oct 28. doi: 10.1111/acel.12413

PMCID:: PMC4717279

Abstract Article PDF–347K

Select item 46067577.

Igfbp2 Deletion in Ovariectomized Mice Enhances Energy Expenditure but Accelerates Bone Loss

Victoria E. DeMambro, Phuong T. Le, Anyonya R. Guntur, David E. Maridas, Ernesto Canalis, Kenichi Nagano, Roland Baron, David R. Clemmons, Clifford J. Rosen

Endocrinology. 2015 Nov; 156(11): 4129–4140. Published online 2015 Jul 31. doi: 10.1210/en.2014-1452

PMCID:: PMC4606757

Abstract Article

Select item 44039438.

Regulation of IGFBP-2 expression during fasting

Hye Suk Kang, Mi-Young Kim, Seung-Jae Kim, Jae-Ho Lee, Yong-Deuk Kim, Young-Kyo Seo, Jae-Hoon Bae, Goo-Taeg Oh, Dae-Kyu Song, Yong-Ho Ahn, Seung-Soon Im

Biochem J. 2015 May 1; 467(Pt 3): 453–460. Prepublished online 2015 Feb 19. Published online 2015 Apr 17. doi: 10.1042/BJ20141248

PMCID:: PMC4403943

Abstract Article PDF–822K

Select item 39119689.

Spatial distribution of insulin-like growth factor binding protein-2 following hypoxic-ischemic injury

Lauren Fletcher, Elif Isgor, Shane Sprague, Lindsey H Williams, Betty B Alajajian, David F Jimenez, Murat Digicaylioglu

BMC Neurosci. 2013; 14: 158. Published online 2013 Dec 21. doi: 10.1186/1471-2202-14-158

PMCID:: PMC3911968

Abstract Article PDF–1.4M

Select item 380075410.

The Heparin-Binding Domains of IGFBP-2 Mediate Its Inhibitory Effect on Preadipocyte Differentiation and Fat Development in Male Mice

Gang Xi, Melissa A. Solum, Christine Wai, Laura A. Maile, Clifford J. Rosen, David R. Clemmons

Endocrinology. 2013 Nov; 154(11): 4146–4157. Published online 2013 Aug 27. doi: 10.1210/en.2013-1236

PMCID:: PMC3800754

Abstract Article

Select item 338541711.

Insulin-like growth factor binding protein-2 is required for osteoclast differentiation

Victoria E DeMambro, Laura Maile, Christine Wai, Masanobu Kawai, Teresa Cascella, Clifford J Rosen, David Clemmons

J Bone Miner Res. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: J Bone Miner Res. 2012 Feb; 27(2): 390–400. doi: 10.1002/jbmr.545

Correction in:: J Bone Miner Res, volume 27 on page 1436

PMCID:: PMC3385417

Abstract Article PDF–2.4M

Select item 232926212.

Gender-Specific Changes in Bone Turnover and Skeletal Architecture in Igfbp-2-Null Mice

V. E. DeMambro, D. R. Clemmons, L. G. Horton, M. L. Bouxsein, T. L. Wood, W. G. Beamer, E. Canalis, C. J. Rosen

Endocrinology. 2008 May; 149(5): 2051–2061. Published online 2008 Feb 14. doi: 10.1210/en.2007-1068

PMCID:: PMC2329262

Abstract Article

Select item 1008250413.

IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma

Haritha Kunhiraman, Leon McSwain, Shubin W. Shahab, Timothy R. Gershon, Tobey J. MacDonald, Anna Marie Kenney

Acta Neuropathol Commun. 2023; 11: 62. Published online 2023 Apr 8. doi: 10.1186/s40478-023-01557-2

PMCID:: PMC10082504

Abstract Article PDF–9.9M

Select item 820042714.

Serum insulin‐like growth factor binding protein 2 levels as biomarker for pancreatic ductal adenocarcinoma‐associated malnutrition and muscle wasting

Jie Dong, Jie Yu, Zekun Li, Song Gao, Hongwei Wang, Shengyu Yang, Liangliang Wu, Chungen Lan, Tiansuo Zhao, Chuntao Gao, Zhe Liu, Xiuchao Wang, Jihui Hao

J Cachexia Sarcopenia Muscle. 2021 Jun; 12(3): 704–716. Published online 2021 Mar 24. doi: 10.1002/jcsm.12692

PMCID:: PMC8200427

Abstract Article PDF–20M

Select item 808023915.

IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery

Justine Faramia, Zheng Hao, Michael B. Mumphrey, R. Leigh Townsend, Stéphanie Miard, Anne-Marie Carreau, Mélanie Nadeau, Frédérique Frisch, Elena-Dana Baraboi, Thomas Grenier-Larouche, Christophe Noll, Meng Li, Laurent Biertho, Simon Marceau, Frédéric-Simon Hould, Stéfane Lebel, Christopher D. Morrison, Heike Münzberg, Denis Richard, André C. Carpentier, André Tchernof, Hans-Rudolf Berthoud, Frédéric Picard

Cell Rep Med. 2021 Apr 20; 2(4): 100248. Published online 2021 Apr 20. doi: 10.1016/j.xcrm.2021.100248

PMCID:: PMC8080239

Abstract Article PDF–2.7M

Select item 731273116.

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

Pia Fahlbusch, Birgit Knebel, Tina Hörbelt, David Monteiro Barbosa, Aleksandra Nikolic, Sylvia Jacob, Hadi Al-Hasani, Frederique Van de Velde, Yves Van Nieuwenhove, Dirk Müller-Wieland, Bruno Lapauw, D. Margriet Ouwens, Jorg Kotzka

Int J Mol Sci. 2020 Jun; 21(11): 4144. Published online 2020 Jun 10. doi: 10.3390/ijms21114144

PMCID:: PMC7312731

Abstract Article PDF–2.6M

Select item 518163117.

Early hypermethylation of hepatic Igfbp2 results in its reduced expression preceding fatty liver in mice

Anne Kammel, Sophie Saussenthaler, Markus Jähnert, Wenke Jonas, Laura Stirm, Andreas Hoeflich, Harald Staiger, Andreas Fritsche, Hans-Ulrich Häring, Hans-Georg Joost, Annette Schürmann, Robert W. Schwenk

Hum Mol Genet. 2016 Jun 15; 25(12): 2588–2599. Published online 2016 Apr 28. doi: 10.1093/hmg/ddw121

PMCID:: PMC5181631

Abstract Article PDF–765K

Select item 385181918.

IGF binding protein 2 is a cell-autonomous factor supporting survival and migration of acute leukemia cells

Xiaoli Chen, Junke Zheng, Yizhou Zou, Chun Song, Xuemei Hu, Cheng Cheng Zhang

J Hematol Oncol. 2013; 6: 72. Published online 2013 Oct 8. doi: 10.1186/1756-8722-6-72

PMCID:: PMC3851819

Abstract Article PDF–1.7M

Select item 380076519.

Human Resistin in Chemotherapy-Induced Heart Failure in Humanized Male Mice and in Women Treated for Breast Cancer

Daniel R. Schwartz, Erika R. Briggs, Mohammed Qatanani, Heloisa Sawaya, Igal A. Sebag, Michael H. Picard, Marielle Scherrer-Crosbie, Mitchell A. Lazar

Endocrinology. 2013 Nov; 154(11): 4206–4214. Published online 2013 Aug 27. doi: 10.1210/en.2013-1399

PMCID:: PMC3800765

Abstract Article

Select item 345733620.

Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase β and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling

Xinchun Shen, Gang Xi, Laura A. Maile, Christine Wai, Clifford J. Rosen, David R. Clemmons

Mol Cell Biol. 2012 Oct; 32(20): 4116–4130. doi: 10.1128/MCB.01011-12

PMCID:: PMC3457336

Abstract Article PDF–2.1M

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