PMC Links for Gene (Select 15937) - PMC

Christian Sina, Alexander Arlt, Olga Gavrilova, Emilie Midtling, Marie-Luise Kruse, Susanne Sebens Müerköster, Rajiv Kumar, Ulrich R. Fölsch, Stefan Schreiber, Philip Rosenstiel, Heiner Schäfer

Inflamm Bowel Dis. Author manuscript; available in PMC 2014 Feb 18.

Published in final edited form as: Inflamm Bowel Dis. 2010 Feb; 16(2): 320–331. doi: 10.1002/ibd.21066

PMCID:: PMC3927407

Abstract Article PDF–3.0M

Select item 39129585.

Stress-induced hematopoietic failure in the absence of immediate early response gene X-1 (IEX-1, IER3)

Haley Ramsey, Qi Zhang, Diane E. Brown, David P. Steensma, Charles P. Lin, Mei X. Wu

Haematologica. 2014 Feb; 99(2): 282–291. doi: 10.3324/haematol.2013.092452

PMCID:: PMC3912958

Abstract Article PDF–1.1M

Select item 34403046.

Enhanced Th17 differentiation and aggravated arthritis in IEX-1-deficient mice by mitochondrial ROS-mediated signaling

Liang Zhi, Irina V. Ustyugova, Xinyuan Chen, Qi Zhang, Mei X. Wu

J Immunol. Author manuscript; available in PMC 2013 Aug 15.

Published in final edited form as: J Immunol. 2012 Aug 15; 189(4): 1639–1647. Published online 2012 Jul 13. doi: 10.4049/jimmunol.1200528

PMCID:: PMC3440304

Abstract Article PDF–2.7M

Select item 74329917.

Uncoupling of CD71 shedding with mitochondrial clearance in reticulocytes in a subset of myelodysplastic syndromes

Qi Zhang, David P. Steensma, Jingke Yang, Tingting Dong, Mei X. Wu

Leukemia. Author manuscript; available in PMC 2020 Aug 18.

Published in final edited form as: Leukemia. 2019 Jan; 33(1): 217–229. Published online 2018 Jul 26. doi: 10.1038/s41375-018-0204-z

PMCID:: PMC7432991

Abstract Article PDF–1.0M

Select item 54123098.

Dysregulated IER3 Expression is Associated with Enhanced Apoptosis in Titin-Based Dilated Cardiomyopathy

Qifeng Zhou, Julia Kelley Hahn, Balram Neupane, Parwez Aidery, Siegfried Labeit, Meinrad Gawaz, Michael Gramlich

Int J Mol Sci. 2017 Apr; 18(4): 723. Published online 2017 Mar 29. doi: 10.3390/ijms18040723

PMCID:: PMC5412309

Abstract Article PDF–2.3M

Select item 43472379.

IER3 supports KRAS^G12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation

Maria Noé Garcia, Daniel Grasso, Maria Belen Lopez-Millan, Tewfik Hamidi, Celine Loncle, Richard Tomasini, Gwen Lomberk, Françoise Porteu, Raul Urrutia, Juan L. Iovanna

J Clin Invest. 2014 Nov 3; 124(11): 4709–4722. Published online 2014 Sep 24. doi: 10.1172/JCI76037

PMCID:: PMC4347237

Abstract Article PDF–2.1M

Select item 410382810.

The Role of Iex-1 in the Pathogenesis of Venous Neointimal Hyperplasia Associated with Hemodialysis Arteriovenous Fistula

Akshaar Brahmbhatt, Evelyn NievesTorres, Binxia Yang, William D. Edwards, Prabir Roy Chaudhury, Min Kyun Lee, Hyunjoon Kong, Debabrata Mukhopadhyay, Rajiv Kumar, Sanjay Misra

PLoS One. 2014; 9(7): e102542. Published online 2014 Jul 18. doi: 10.1371/journal.pone.0102542

Correction in:: PLoS One. 2014; 9(9): e110196.

PMCID:: PMC4103828

Abstract Article PDF–2.0M

Select item 315725211.

IMPAIRED cAMP-MEDIATED SIGNALING IN IEX-1-DEFICIENT VASCULAR SMOOTH MUSCLE CELLS

Mohd Shahid, Li Shen, David C. Seldin, Bao Lu, Irina V. Ustyugova, Xinyuan Chen, Warren M. Zapol, Mei X. Wu

Hypertension. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Hypertension. 2010 Oct; 56(4): 705–712. Published online 2010 Aug 16. doi: 10.1161/HYPERTENSIONAHA.110.154880

PMCID:: PMC3157252

Abstract Article PDF–1.9M

Select item 315724312.

Priority Report: Rearrangements and Amplification of IER3 (IEX-1) Represent A Novel And Recurrent Molecular Abnormality In Myelodysplastic Syndromes (MDS)

David P. Steensma, Jessemy D. Neiger, Julie C. Porcher, J. Jonathan Keats, P. Leif Bergsagel, Thomas R. Dennis, Ryan A. Knudson, Robert B. Jenkins, Rafael Santana-Davila, Rajiv Kumar, Rhett P. Ketterling

Cancer Res. Author manuscript; available in PMC 2011 Aug 17.

Published in final edited form as: Cancer Res. 2009 Oct 1; 69(19): 7518–7523. Published online 2009 Sep 22. doi: 10.1158/0008-5472.CAN-09-1428

PMCID:: PMC3157243

Abstract Article PDF–963K

Select item 11739913.

Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice

Y. Zhang, S. F. Schlossman, R. A. Edwards, Ching-Nan Ou, J. Gu, Mei X. Wu

Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2): 878–883. Published online 2002 Jan 8. doi: 10.1073/pnas.022326699

PMCID:: PMC117399

Abstract Article PDF–250K

Select item 346594714.

IEX-1 deficiency protects against colonic cancer

Irina V. Ustyugova, Liang Zhi, Joel Abramowitz, Lutz Birnbaumer, Mei X. Wu

Mol Cancer Res. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Mol Cancer Res. 2012 Jun; 10(6): 760–767. Published online 2012 May 1. doi: 10.1158/1541-7786.MCR-11-0556

PMCID:: PMC3465947

Abstract Article PDF–1.2M

Select item 446787315.

Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1

Bérengère de Laval, Patrycja Pawlikowska, Daniela Barbieri, Corinne Besnard-Guerin, Alba Cico, Rajiv Kumar, Murielle Gaudry, Véronique Baud, Françoise Porteu

Blood. 2014 Jan 23; 123(4): 509–519. Prepublished online 2013 Nov 1. doi: 10.1182/blood-2013-07-515874

PMCID:: PMC4467873

Abstract Article

Select item 390094216.

Modulation of Nuclear Factor E2-related Factor-2 (Nrf2) Activation by the Stress Response Gene Immediate Early Response-3 (IER3) in Colonic Epithelial Cells: A NOVEL MECHANISM OF CELLULAR ADAPTION TO INFLAMMATORY STRESS

Imke Stachel, Claudia Geismann, Konrad Aden, Florian Deisinger, Philip Rosenstiel, Stefan Schreiber, Susanne Sebens, Alexander Arlt, Heiner Schäfer

J Biol Chem. 2014 Jan 24; 289(4): 1917–1929. Published online 2013 Dec 5. doi: 10.1074/jbc.M113.490920

PMCID:: PMC3900942

Abstract Article PDF–3.1M

Select item 269639117.

IEX-1 targets mitochondrial F1Fo-ATPase inhibitor for degradation

L Shen, L Zhi, W Hu, MX Wu

Cell Death Differ. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: Cell Death Differ. 2009 Apr; 16(4): 603–612. Published online 2008 Dec 19. doi: 10.1038/cdd.2008.184

PMCID:: PMC2696391

Abstract Article PDF–986K

Select item 392332618.

ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response

P Pawlikowska, I Leray, B de Laval, S Guihard, R Kumar, F Rosselli, F Porteu

Cell Death Differ. Author manuscript; available in PMC 2014 Feb 13.

Published in final edited form as: Cell Death Differ. 2010 Nov; 17(11): 1739–1750. Published online 2010 May 14. doi: 10.1038/cdd.2010.56

PMCID:: PMC3923326

Abstract Article PDF–4.2M

Select item 1088403019.

TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome

Elizabeth A. Werren, Geneva R. LaForce, Anshika Srivastava, Delia R. Perillo, Shaokun Li, Katherine Johnson, Safa Baris, Brandon Berger, Samantha L. Regan, Christian D. Pfennig, Sonja de Munnik, Rolph Pfundt, Malavika Hebbar, Raúl Jimenez-Heredia, Elif Karakoc-Aydiner, Ahmet Ozen, Jasmin Dmytrus, Ana Krolo, Ken Corning, E. J. Prijoles, Raymond J. Louie, Robert Roger Lebel, Thuy-Linh Le, Jeanne Amiel, Christopher T. Gordon, Kaan Boztug, Katta M. Girisha, Anju Shukla, Stephanie L. Bielas, Ashleigh E. Schaffer

Nat Commun. 2024; 15: 1640. Published online 2024 Feb 22. doi: 10.1038/s41467-024-45948-y

PMCID:: PMC10884030

Abstract Article PDF–7.0M

Select item 361451120.

Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis Via TGF-β–TAK1–Dependent Mechanism

Yulei Shang, Christina N. Doan, Thomas D. Arnold, Sebum Lee, Amy A. Tang, Louis F. Reichardt, Eric J. Huang

PLoS Biol. 2013 Apr; 11(4): e1001527. Published online 2013 Apr 2. doi: 10.1371/journal.pbio.1001527

PMCID:: PMC3614511

Abstract Article PDF–1.7M

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