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Select item 105826631.

Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients

Alaa Alghamdi, Sarah Seay, David K. Hooper, Charles D. Varnell, Jr., Leanna Darland, Tomoyuki Mizuno, Danielle Lazear, Laura B. Ramsey

Clin Transl Sci. 2023 Oct; 16(10): 1768–1778. Published online 2023 Jun 26. doi: 10.1111/cts.13571

PMCID:: PMC10582663

Abstract Article PDF–3.6M

Select item 99332782.

Pharmacogenetics in critical care: association between CYP3A5 rs776746 A/G genotype and acetaminophen response in sepsis and septic shock

C. Scorcella, R. Domizi, S. Amoroso, A. Carsetti, E. Casarotta, P. Castaldo, C. D’angelo, E. Damiani, F. Gasparri, A. Donati, E. Adrario

BMC Anesthesiol. 2023; 23: 55. Published online 2023 Feb 16. doi: 10.1186/s12871-023-02018-y

PMCID:: PMC9933278

Abstract Article PDF–966K

Select item 92491493.

Evaluation of genetic polymorphism of CYP3A5 in normal healthy participants from western India - A cross-sectional study

Miteshkumar Rajaram Maurya, Sunanda Gautam, Jeffrey Pradeep Raj, Shruti Saha, Sanchita Ambre, Aishwarya Thakurdesai, Aditya Shah, Urmila Mukund Thatte

Indian J Pharmacol. 2022 Mar-Apr; 54(2): 97–101. Published online 2022 May 10. doi: 10.4103/ijp.ijp_279_21

PMCID:: PMC9249149

Abstract Article

Select item 85163354.

The CYP3A5 genotypes of both liver transplant recipients and donors influence the time‐dependent recovery of tacrolimus clearance during the early stage following transplantation

Li Huang, Abdullah A. Assiri, Peihao Wen, Kun Zhang, Junwei Fan, Tonghai Xing, Yuan Liu, Jinyan Zhang, Zhaowen Wang, Zhaojie Su, Jiajia Chen, Yi Xiao, Rui Wang, Risi Na, Liyun Yuan, Dehua Liu, Junjie Xia, Lin Zhong, Wanqing Liu, Wenzhi Guo, Brian R. Overholser, Zhihai Peng

Clin Transl Med. 2021 Oct; 11(10): e542. Published online 2021 Oct 14. doi: 10.1002/ctm2.542

PMCID:: PMC8516335

Article PDF–1.3M

Select item 80094825.

CYP3A5 genotype affects time to therapeutic tacrolimus level in pediatric kidney transplant recipients

Megan V. Yanik, Michael E. Seifert, Jayme E. Locke, Vera Hauptfeld-Dolejsek, Michael R. Crowley, Gary R. Cutter, Roslyn B. Mannon, Daniel I. Feig, Nita A. Limdi

Pediatr Transplant. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Pediatr Transplant. 2019 Aug; 23(5): e13494. Published online 2019 May 24. doi: 10.1111/petr.13494

PMCID:: PMC8009482

Abstract Article PDF–694K

Select item 71780106.

Influence of POR*28 Polymorphisms on CYP3A5*3-Associated Variations in Tacrolimus Blood Levels at an Early Stage after Liver Transplantation

Takahiro Nakamura, Mio Fukuda, Ryosuke Matsukane, Kimitaka Suetsugu, Noboru Harada, Tomoharu Yoshizumi, Nobuaki Egashira, Masaki Mori, Satohiro Masuda

Int J Mol Sci. 2020 Apr; 21(7): 2287. Published online 2020 Mar 26. doi: 10.3390/ijms21072287

PMCID:: PMC7178010

Abstract Article PDF–4.1M

Select item 57663757.

CYP3A5 genotype and its impact on vincristine pharmacokinetics and development of neuropathy in Kenyan children with cancer

Jodi L. Skiles, ChienWei Chiang, Claire H. Li, Steve Martin, Ellen L. Smith, Gilbert Olbara, David R. Jones, Terry A. Vik, Saskia Mostert, Floor Abbink, Gertjan J. Kaspers, Lang Li, Festus Njuguna, Tammy J. Sajdyk, Jamie L. Renbarger

Pediatr Blood Cancer. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Pediatr Blood Cancer. 2018 Mar; 65(3): 10.1002/pbc.26854. Published online 2017 Nov 8. doi: 10.1002/pbc.26854

PMCID:: PMC5766375

Abstract Article PDF–205K

Select item 55187188.

CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism

Casey R. Dorr, Rory P. Remmel, Amutha Muthusamy, James Fisher, Branden S. Moriarity, Kazuto Yasuda, Baolin Wu, Weihua Guan, Erin G. Schuetz, William S. Oetting, Pamala A. Jacobson, Ajay K. Israni

Drug Metab Dispos. 2017 Aug; 45(8): 957–965. Published online 2017 Aug. doi: 10.1124/dmd.117.076307

PMCID:: PMC5518718

Abstract Article PDF–917K

Select item 54388219.

Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3

Ayano Ito, Yuko Okada, Tadahiro Hashita, Tohru Aomori, Keiju Hiromura, Yoshihisa Nojima, Tomonori Nakamura, Takuya Araki, Koujirou Yamamoto

Biochem Genet. 2017; 55(3): 268–277. Published online 2017 Mar 21. doi: 10.1007/s10528-017-9795-8

PMCID:: PMC5438821

Abstract Article PDF–593K

Select item 543628610.

Effects of cytochrome P450 family 3 subfamily A member 5 gene polymorphisms on daunorubicin metabolism and adverse reactions in patients with acute leukemia

Zhen Huang, Juxiang Wang, Jiangchao Qian, Yuan Li, Zhisheng Xu, Min Chen, Hongfei Tong

Mol Med Rep. 2017 Jun; 15(6): 3493–3498. Published online 2017 Apr 12. doi: 10.3892/mmr.2017.6470

PMCID:: PMC5436286

Abstract Article PDF–818K

Select item 542724411.

Donor CYP3A5 genotype influences tacrolimus disposition on the first day after paediatric liver transplantation

Pier Luigi Calvo, Loredana Serpe, Andrea Brunati, Antonello Nonnato, Daniela Bongioanni, Dominic Dell' Olio, Michele Pinon, Carlo Ferretti, Francesco Tandoi, Giulia Carbonaro, Mauro Salizzoni, Antonio Amoroso, Renato Romagnoli, Roberto Canaparo

Br J Clin Pharmacol. 2017 Jun; 83(6): 1252–1262. Published online 2017 Jan 31. doi: 10.1111/bcp.13219

PMCID:: PMC5427244

Abstract Article PDF–696K

Select item 536497212.

Construction and verification of CYP3A5 gene polymorphisms using a Saccharomyces cerevisiae expression system to predict drug metabolism

Yao Lu, Hua Zhong, Qing Tang, Zhijun Huang, Ningning Jing, Julie Smith, Rujia Miao, Yapei Li, Hong Yuan

Mol Med Rep. 2017 Apr; 15(4): 1593–1600. Published online 2017 Feb 17. doi: 10.3892/mmr.2017.6214

PMCID:: PMC5364972

Abstract Article PDF–1.2M

Select item 473340813.

Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles

W. S. Oetting, D. P. Schladt, W. Guan, M. B. Miller, R. P. Remmel, C. Dorr, K. Sanghavi, R. B. Mannon, B. Herrera, A. J. Matas, D. R. Salomon, P.-Y. Kwok, B. J. Keating, A. K. Israni, P. A. Jacobson

Am J Transplant. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Am J Transplant. 2016 Feb; 16(2): 574–582. Published online 2015 Oct 20. doi: 10.1111/ajt.13495

PMCID:: PMC4733408

Abstract Article PDF–309K

Select item 469349814.

CYP3A5 polymorphism affects the increase in CYP3A activity after living kidney transplantation in patients with end stage renal disease

Yosuke Suzuki, Takashi Fujioka, Fuminori Sato, Kunihiro Matsumoto, Nanako Muraya, Ryota Tanaka, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata, Satoshi Kishino, Hiroki Itoh

Br J Clin Pharmacol. 2015 Dec; 80(6): 1421–1428. Published online 2015 Oct 3. doi: 10.1111/bcp.12733

PMCID:: PMC4693498

Abstract Article PDF–1.1M

Select item 454635315.

The Absence of CYP3A5*3 Is a Protective Factor to Anticonvulsants Hypersensitivity Reactions: A Case-Control Study in Brazilian Subjects

Luciana Kase Tanno, Daniel Shikanai Kerr, Bernardo dos Santos, Leda Leme Talib, Célia Yamaguti, Helcio Rodrigues, Wagner Farid Gattaz, Jorge Kalil

PLoS One. 2015; 10(8): e0136141. Published online 2015 Aug 20. doi: 10.1371/journal.pone.0136141

Correction in:: PLoS One. 2015; 10(9): e0139861.

PMCID:: PMC4546353

Abstract Article PDF–325K

Select item 453007716.

Effect of CYP3A5*3 on Asthma Control among Children Treated with Inhaled Beclomethasone

Chris Stockmann, Christopher A. Reilly, Bernhard Fassl, Roger Gaedigk, Flory Nkoy, Bryan Stone, Jessica K. Roberts, Derek A. Uchida, J. Steven Leeder, Catherine M.T. Sherwin, Michael G. Spigarelli, Garold S. Yost, Robert M. Ward

J Allergy Clin Immunol. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: J Allergy Clin Immunol. 2015 Aug; 136(2): 505–507. Published online 2015 Mar 29. doi: 10.1016/j.jaci.2015.02.009