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Select item 107121961.

Vesicular HMGB1 release from neurons stressed with spreading depolarization enables confined inflammatory signaling to astrocytes

Zeynep Kaya, Nevin Belder, Melike Sever-Bahcekapili, Buket Donmez-Demir, Şefik Evren Erdener, Naz Bozbeyoglu, Canan Bagci, Emine Eren-Kocak, Muge Yemisci, Hulya Karatas, Esra Erdemli, Ihsan Gursel, Turgay Dalkara

J Neuroinflammation. 2023; 20: 295. Published online 2023 Dec 11. doi: 10.1186/s12974-023-02977-6

PMCID:: PMC10712196

Abstract Article PDF–2.9M

Select item 105186532.

Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong

Eur J Histochem. 2023 Jul 26; 67(3): 3704. Published online 2023 Sep 1. doi: 10.4081/ejh.2023.3704

PMCID:: PMC10518653

Abstract Article PDF–23M

Select item 104324803.

Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation

Moises Freitas-Andrade, Cesar H. Comin, Peter Van Dyken, Julie Ouellette, Joanna Raman-Nair, Nicole Blakeley, Qing Yan Liu, Sonia Leclerc, Youlian Pan, Ziying Liu, Micaël Carrier, Karan Thakur, Alexandre Savard, Gareth M. Rurak, Marie-Ève Tremblay, Natalina Salmaso, Luciano da F. Costa, Gianfilippo Coppola, Baptiste Lacoste

Nat Commun. 2023; 14: 4965. Published online 2023 Aug 16. doi: 10.1038/s41467-023-40682-3

PMCID:: PMC10432480

Abstract Article PDF–20M

Select item 102175564.

Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain

Shaojing Ye, Dlovan F. D. Mahmood, Fei Ma, Lin Leng, Richard Bucala, Pedro L. Vera

Cells. 2023 May; 12(10): 1440. Published online 2023 May 22. doi: 10.3390/cells12101440

PMCID:: PMC10217556

Abstract Article PDF–61M

Select item 101405195.

Inhibition of macrophages inflammasome activation via autophagic degradation of HMGB1 by EGCG ameliorates HBV-induced liver injury and fibrosis

Minjing He, Tianhao Chu, Ziteng Wang, Ying Feng, Runhan Shi, Muyang He, Siheng Feng, Lin Lu, Chen Cai, Fang Fang, Xuemin Zhang, Yi Liu, Bo Gao

Front Immunol. 2023; 14: 1147379. Published online 2023 Apr 14. doi: 10.3389/fimmu.2023.1147379

PMCID:: PMC10140519

Abstract Article PDF–8.1M

Select item 100078186.

HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy

Xiao-Yu Yin, Xiao-Hui Tang, Shi-Xu Wang, Yong-Chang Zhao, Min Jia, Jian-Jun Yang, Mu-Huo Ji, Jin-Chun Shen

J Neuroinflammation. 2023; 20: 69. Published online 2023 Mar 11. doi: 10.1186/s12974-023-02756-3

PMCID:: PMC10007818

Abstract Article PDF–8.1M

Select item 97460427.

Suppression of high mobility group box 1 in B16F10 tumor does not inhibit the induction of neoantigen‐specific T cells

Kayoko Waki, Miyako Ozawa, Akira Yamada

Cancer Sci. 2022 Dec; 113(12): 4082–4091. Published online 2022 Sep 15. doi: 10.1111/cas.15563

PMCID:: PMC9746042

Abstract Article PDF–2.2M

Select item 96721738.

HMGB1 from Astrocytes Promotes EAE by Influencing the Immune Cell Infiltration-Associated Functions of BMECs in Mice

Junyu Shi, Yifan Xiao, Na Zhang, Mengya Jiao, Xuhuan Tang, Chan Dai, Chenchen Wang, Yong Xu, Zheng Tan, Feili Gong, Fang Zheng

Neurosci Bull. 2022 Nov; 38(11): 1303–1314. Published online 2022 Jun 13. doi: 10.1007/s12264-022-00890-1

PMCID:: PMC9672173

Abstract Article PDF–3.2M

Select item 93787879.

The HMGB1 (C106A) mutation inhibits IL-10-producing CD19^hiFcγRIIb^hi B cell expansion by suppressing STAT3 activation in mice

Mengru Liu, Jingwen Zhou, Rui Yin, Hui Yin, Yue Ding, Feng Ma, Li Qian

Front Immunol. 2022; 13: 975551. Published online 2022 Aug 2. doi: 10.3389/fimmu.2022.975551

PMCID:: PMC9378787

Abstract Article PDF–14M

Select item 931512210.

Ablation of high‐mobility group box‐1 in the liver reduces hepatocellular carcinoma but causes hyperbilirubinemia in Hippo signaling‐deficient mice

Dipti Athavale, Zhuolun Song, Romain Desert, Hui Han, Sukanta Das, Xiaodong Ge, Sai Santosh Babu Komakula, Wei Chen, Shenglan Gao, Daniel Lantvit, Grace Guzman, Natalia Nieto

Hepatol Commun. 2022 Aug; 6(8): 2155–2169. Published online 2022 Mar 28. doi: 10.1002/hep4.1943

PMCID:: PMC9315122

Abstract Article PDF–5.0M

Select item 922138111.

Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1

Heshuang Qu, Rebecka Heinbäck, Henna Salo, Ewoud Ewing, Alexander Espinosa, Cecilia Aulin, Helena Erlandsson Harris

Biomolecules. 2022 Jun; 12(6): 779. Published online 2022 Jun 2. doi: 10.3390/biom12060779

PMCID:: PMC9221381

Abstract Article PDF–3.7M

Select item 907529412.

Haptoglobin Regulates Macrophage/Microglia‐Induced Inflammation and Prevents Ischemic Brain Damage Via Binding to HMGB1

Mayuka Morimoto, Takafumi Nakano, Saki Egashira, Keiichi Irie, Kiyoshi Matsuyama, Momoka Wada, Yoshihiko Nakamura, Yutaka Shigemori, Hiroyasu Ishikura, Yuta Yamashita, Kazuhide Hayakawa, Kazunori Sano, Kenichi Mishima

J Am Heart Assoc. 2022 Mar 15; 11(6): e024424. Published online 2022 Mar 4. doi: 10.1161/JAHA.121.024424

PMCID:: PMC9075294

Abstract Article PDF–1.3M

Select item 849005913.

Release of HMGB1 in Podocytes Exacerbates Lipopolysaccharide-Induced Acute Kidney Injury

Zhao Gao, Li Lu, Xinghua Chen

Mediators Inflamm. 2021; 2021: 5220226. Published online 2021 Sep 27. doi: 10.1155/2021/5220226

PMCID:: PMC8490059

Abstract Article PDF–1.6M

Select item 843919814.

Brain Microvascular Endothelial Cell-Derived HMGB1 Facilitates Monocyte Adhesion and Transmigration to Promote JEV Neuroinvasion

Song-Song Zou, Qing-Cui Zou, Wen-Jing Xiong, Ning-Yi Cui, Ke Wang, Hao-Xuan Liu, Wen-Juan Lou, Doaa Higazy, Ya-Ge Zhang, Min Cui

Front Cell Infect Microbiol. 2021; 11: 701820. Published online 2021 Aug 31. doi: 10.3389/fcimb.2021.701820

Correction in:: Front Cell Infect Microbiol. 2022; 12: 964880.

Correction in:: Front Cell Infect Microbiol. 2021; 11: 771928.

PMCID:: PMC8439198

Abstract Article PDF–6.5M

Select item 839425115.

Conditional Knock out of High-Mobility Group Box 1 (HMGB1) in Rods Reduces Autophagy Activation after Retinal Detachment

Bing X. Ross, Lin Jia, Dejuan Kong, Tiantian Wang, Heather M. Hager, Steven F. Abcouwer, David N. Zacks

Cells. 2021 Aug; 10(8): 2010. Published online 2021 Aug 6. doi: 10.3390/cells10082010

PMCID:: PMC8394251

Abstract Article PDF–1.8M

Select item 822995716.

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

Henna Salo, Heshuang Qu, Dimitra Mitsiou, Hannah Aucott, Jinming Han, Xingmei Zhang, Cecilia Aulin, Helena Erlandsson Harris

Biomolecules. 2021 Jun; 11(6): 800. Published online 2021 May 28. doi: 10.3390/biom11060800

PMCID:: PMC8229957

Abstract Article PDF–6.5M

Select item 806681017.

Inhibition of Cochlear HMGB1 Expression Attenuates Oxidative Stress and Inflammation in an Experimental Murine Model of Noise-Induced Hearing Loss

Cheng-Ping Shih, Chao-Yin Kuo, Yuan-Yung Lin, Yi-Chun Lin, Hang-Kang Chen, Hao Wang, Hsin-Chien Chen, Chih-Hung Wang

Cells. 2021 Apr; 10(4): 810. Published online 2021 Apr 5. doi: 10.3390/cells10040810

PMCID:: PMC8066810

Abstract Article PDF–5.0M

Select item 805172218.

High‐mobility group box‐1 promotes vascular calcification in diabetic mice via endoplasmic reticulum stress

Zheng Chen, Ran Li, Li‐Gang Pei, Zhong‐Hai Wei, Jun Xie, Han Wu, Biao Xu

J Cell Mol Med. 2021 Apr; 25(8): 3724–3734. Published online 2021 Mar 16. doi: 10.1111/jcmm.16075

PMCID:: PMC8051722

Abstract Article PDF–1.3M

Select item 798822219.

Extracellular HMGB1 Contributes to the Chronic Cardiac Allograft Vasculopathy/Fibrosis by Modulating TGF-β1 Signaling

Huijuan Zou, Bingxia Ming, Jun Li, Yifan Xiao, Lin Lai, Ming Gao, Yong Xu, Zheng Tan, Feili Gong, Fang Zheng

Front Immunol. 2021; 12: 641973. Published online 2021 Mar 10. doi: 10.3389/fimmu.2021.641973

PMCID:: PMC7988222

Abstract Article PDF–6.9M

Select item 781711720.

HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis

Naoyuki Senda, Hideyuki Yanai, Sana Hibino, Lei Li, Yu Mizushima, Tomomitsu Miyagaki, Mai Saeki, Yusuke Kishi, Sho Hangai, Junko Nishio, Makoto Sugaya, Tadatsugu Taniguchi, Shinichi Sato

Proc Natl Acad Sci U S A. 2021 Jan 5; 118(1): e2022343118. Published online 2020 Dec 21. doi: 10.1073/pnas.2022343118