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Items: 1 to 20 of 463

1.
The role of preproglucagon peptides in regulating β-cell morphology and responses to streptozotocin-induced diabetes
Deanna M. Arble, Chelsea R. Hutch, Hannah Hafner, Daria Stelmak, Kyle Leix, Joyce Sorrell, Joshua W. Pressler, Brigid Gregg, Darleen A. Sandoval
Am J Physiol Endocrinol Metab. 2023 Mar 1; 324(3): E217–E225. Published online 2023 Jan 18. doi: 10.1152/ajpendo.00152.2022
PMCID:
PMC9970646
AbstractArticle
2.
GLP-1 attenuates intestinal fat absorption and chylomicron production via vagal afferent nerves originating in the portal vein
Simon Hoffman, Danielle Alvares, Khosrow Adeli
Mol Metab. 2022 Nov; 65: 101590. Published online 2022 Sep 5. doi: 10.1016/j.molmet.2022.101590
PMCID:
PMC9486018
AbstractArticlePDF–2.2M
3.
Disrupted and Elevated Circadian Secretion of Glucagon-Like Peptide-1 in a Murine Model of Type 2 Diabetes
Andrew D Biancolin, Hyerin Jeong, Kimberly W Y Mak, Zixuan Yuan, Patricia L Brubaker
Endocrinology. 2022 Sep; 163(9): bqac118. Published online 2022 Jul 25. doi: 10.1210/endocr/bqac118
PMCID:
PMC9368029
AbstractArticle
4.
Pancreatic β Cells Inhibit Glucagon Secretion from α Cells: An In Vitro Demonstration of α–β Cell Interaction
Wenqian Gu, Camilla Christine Bundgaard Anker, Christine Bodelund Christiansen, Tilo Moede, Per-Olof Berggren, Kjeld Hermansen, Søren Gregersen, Per Bendix Jeppesen
Nutrients. 2021 Jul; 13(7): 2281. Published online 2021 Jun 30. doi: 10.3390/nu13072281
PMCID:
PMC8308288
AbstractArticlePDF–5.3M
5.
Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice
Youngmi Song, Jacqueline A. Koehler, Laurie L. Baggio, Alvin C. Powers, Darleen A. Sandoval, Daniel J. Drucker
Cell Metab. Author manuscript; available in PMC 2021 May 22.
Published in final edited form as: Cell Metab. 2019 Nov 5; 30(5): 976–986.e3. Published online 2019 Sep 5. doi: 10.1016/j.cmet.2019.08.009
PMCID:
PMC8140521
AbstractArticlePDF–1.6M
6.
The Role of the Bacterial Muramyl Dipeptide in the Regulation of GLP-1 and Glycemia
Laura Williams, Amal Alshehri, Bianca Robichaud, Alison Cudmore, Jeffrey Gagnon
Int J Mol Sci. 2020 Aug; 21(15): 5252. Published online 2020 Jul 24. doi: 10.3390/ijms21155252
PMCID:
PMC7432949
AbstractArticlePDF–2.1M
7.
Functional and molecular adaptations of enteroendocrine L-cells in male obese mice are associated with preservation of pancreatic alpha-cells function and prevention of hyperglycemia
Rodolphe Dusaulcy, Sandra Handgraaf, Svetlana Skarupelova, Florian Visentin, Christian Vesin, Mounia Heddad-Masson, Frank Reimann, Fiona Gribble, Jacques Philippe, Yvan Gosmain
Endocrinology. Author manuscript; available in PMC 2020 May 15.
Published in final edited form as: Endocrinology. 2016 Oct 1; 157(10): 3832–3843. Published online 2016 Aug 22. doi: 10.1210/en.2016-1433
PMCID:
PMC7228810
AbstractArticlePDF–2.1M
8.
Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion
Brandon L. Panaro, Bernardo Yusta, Dianne Matthews, Jacqueline A. Koehler, Youngmi Song, Darleen A. Sandoval, Daniel J. Drucker
Mol Metab. 2020 Jul; 37: 100990. Published online 2020 Apr 9. doi: 10.1016/j.molmet.2020.100990
PMCID:
PMC7200938
AbstractArticlePDF–2.4M
9.
The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition
Megan E. Capozzi, Reilly W. Coch, Jepchumba Koech, Inna I. Astapova, Jacob B. Wait, Sara E. Encisco, Jonathan D. Douros, Kimberly El, Brian Finan, Kyle W. Sloop, Mark A. Herman, David A. D’Alessio, Jonathan E. Campbell
Diabetes. 2020 May; 69(5): 882–892. Published online 2020 Jan 31. doi: 10.2337/db19-1216
PMCID:
PMC7171961
AbstractArticlePDF–1.5M
10.
Central and peripheral GLP-1 systems independently suppress eating
Daniel I. Brierley, Marie K. Holt, Arashdeep Singh, Alan de Araujo, Molly McDougle, Macarena Vergara, Majd H. Afaghani, Shin Jae Lee, Karen Scott, Calyn Maske, Wolfgang Langhans, Eric Krause, Annette de Kloet, Fiona M. Gribble, Frank Reimann, Linda Rinaman, Guillaume de Lartigue, Stefan Trapp
Nat Metab. Author manuscript; available in PMC 2021 Aug 15.
Published in final edited form as: Nat Metab. 2021 Feb; 3(2): 258–273. Published online 2021 Feb 15. doi: 10.1038/s42255-021-00344-4
PMCID:
PMC7116821
AbstractArticlePDF–5.9M
11.
Glycemic effect of pancreatic preproglucagon in mouse sleeve gastrectomy
Ki-Suk Kim, Chelsea R. Hutch, Landon Wood, Irwin J. Magrisso, Randy J. Seeley, Darleen A. Sandoval
JCI Insight. 2019 Oct 17; 4(20): e129452. Published online 2019 Oct 17. doi: 10.1172/jci.insight.129452
PMCID:
PMC6824314
AbstractArticlePDF–1.8M
12.
The role of GIP and pancreatic GLP-1 in the glucoregulatory effect of DPP-4 inhibition in mice
Chelsea R. Hutch, Karen Roelofs, April Haller, Joyce Sorrell, Kyle Leix, David D. D’Alessio, Robert Augustin, Randy J. Seeley, Thomas Klein, Darleen A. Sandoval
Diabetologia. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Diabetologia. 2019 Oct; 62(10): 1928–1937. Published online 2019 Aug 14. doi: 10.1007/s00125-019-4963-5
PMCID:
PMC6732043
AbstractArticlePDF–751K
13.
Glucagon-Like Peptide 1 Excites Hypocretin/Orexin Neurons by Direct and Indirect Mechanisms: Implications for Viscera-Mediated Arousal
Claudio Acuna-Goycolea, Anthony van den Pol
J Neurosci. 2004 Sep 15; 24(37): 8141–8152. doi: 10.1523/JNEUROSCI.1607-04.2004
PMCID:
PMC6729787
AbstractArticlePDF–645K
14.
Liraglutide, a human glucagon‐like peptide‐1 analogue, stimulates AKT‐dependent survival signalling and inhibits pancreatic β‐cell apoptosis
Katerina Kapodistria, Effie‐Photini Tsilibary, Eleni Kotsopoulou, Petros Moustardas, Paraskevi Kitsiou
J Cell Mol Med. 2018 Jun; 22(6): 2970–2980. Published online 2018 Mar 10. doi: 10.1111/jcmm.13259
PMCID:
PMC5980190
AbstractArticlePDF–1.1M
15.
Glucagon contributes to liver zonation
Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada
Proc Natl Acad Sci U S A. 2018 Apr 24; 115(17): E4111–E4119. Published online 2018 Mar 19. doi: 10.1073/pnas.1721403115
PMCID:
PMC5924920
AbstractArticlePDF–2.1M
16.
Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity
Xuemei Shi, Shaji Chacko, Feng Li, Depei Li, Douglas Burrin, Lawrence Chan, Xinfu Guan
Mol Metab. 2017 Nov; 6(11): 1350–1359. Published online 2017 Sep 1. doi: 10.1016/j.molmet.2017.08.009
PMCID:
PMC5681239
AbstractArticlePDF–3.7M
17.
Mice Deficient for Glucagon Gene-Derived Peptides Display Normoglycemia and Hyperplasia of Islet α-Cells But Not of Intestinal L-Cells
Yoshitaka Hayashi, Michiyo Yamamoto, Hiroyuki Mizoguchi, Chika Watanabe, Ryoichi Ito, Shiori Yamamoto, Xiao-yang Sun, Yoshiharu Murata
Mol Endocrinol. December 1, 2009; 23(12): 1990–1999. doi: 10.1210/me.2009-0296
PMCID:
PMC5419124
AbstractArticle
18.
Direct Regulation of the Proglucagon Gene by Insulin, Leptin, and cAMP in Embryonic versus Adult Hypothalamic Neurons
Prasad S. Dalvi, Frederick D. Erbiceanu, David M. Irwin, Denise D. Belsham
Mol Endocrinol. August 1, 2012; 26(8): 1339–1355. Published online 2012 Jun 5. doi: 10.1210/me.2012-1049
PMCID:
PMC5416985
AbstractArticle
19.
Activation of murine pre-proglucagon–producing neurons reduces food intake and body weight
Ronald P. Gaykema, Brandon A. Newmyer, Matteo Ottolini, Vidisha Raje, Daniel M. Warthen, Philip S. Lambeth, Maria Niccum, Ting Yao, Yiru Huang, Ira G. Schulman, Thurl E. Harris, Manoj K. Patel, Kevin W. Williams, Michael M. Scott
J Clin Invest. 2017 Mar 1; 127(3): 1031–1045. Published online 2017 Feb 20. doi: 10.1172/JCI81335
PMCID:
PMC5330725
AbstractArticlePDF–2.8M
20.
Endogenous Glucagon-like peptide-1 suppresses high-fat food intake by reducing synaptic drive onto mesolimbic dopamine neurons
Xue-Feng Wang, Jing-Jing Liu, Julia Xia, Ji Liu, Vincent Mirabella, Zhiping P. Pang
Cell Rep. Author manuscript; available in PMC 2016 May 8.
Published in final edited form as: Cell Rep. 2015 Aug 4; 12(5): 726–733. Published online 2015 Jul 23. doi: 10.1016/j.celrep.2015.06.062
PMCID:
PMC4860285
AbstractArticlePDF–2.2M

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