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Select item 102143021.

G0S2 promotes antiestrogenic and pro-migratory responses in ER+ and ER- breast cancer cells

Andrea K. Corbet, Emmanuel Bikorimana, Raya I. Boyd, Doha Shokry, Kelly Kries, Ayush Gupta, Anneliese Paton, Zhengyang Sun, Zeeshan Fazal, Sarah J. Freemantle, Erik R. Nelson, Michael J. Spinella, Ratnakar Singh

Transl Oncol. 2023 Jul; 33: 101676. Published online 2023 Apr 20. doi: 10.1016/j.tranon.2023.101676

PMCID:: PMC10214302

Abstract Article PDF–3.5M

Select item 100767702.

The effect of G0S2 on insulin sensitivity: A proteomic analysis in a G0S2-overexpressed high-fat diet mouse model

Dongming Wu, Zhenyuan Zhang, Wenxiu Sun, Yong Yan, Mengzhe Jing, Shizhan Ma

Front Endocrinol (Lausanne) 2023; 14: 1130350. Published online 2023 Mar 23. doi: 10.3389/fendo.2023.1130350

PMCID:: PMC10076770

Abstract Article PDF–5.6M

Select item 50011623.

Deletion of G0/G1 Switch Gene 2 prevents obesity and insulin resistance and promotes browning of white adipose tissue

Wissal El-Assaad, Karim El-Kouhen, Amro H. Mohammad, Jieyi Yang, Masahiro Morita, Isabelle Gamache, Orval Mamer, Daina Avizonis, Nicole Hermance, Sander Kersten, Michel L. Tremblay, Michelle A. Kelliher, Jose G. Teodoro

Diabetologia. Author manuscript; available in PMC 2016 Aug 26.

Published in final edited form as: Diabetologia. 2015 Jan; 58(1): 149–157. Published online 2014 Nov 9. doi: 10.1007/s00125-014-3429-z

PMCID:: PMC5001162

Abstract Article PDF–3.0M

Select item 47753374.

G0S2 suppresses oncogenic transformation by repressing a Myc-regulated transcriptional program

Christina Y. Yim, David J. Sekula, Mary P. Hever-Jardine, Xi Liu, Joshua M. Warzecha, Janice Tam, Sarah J. Freemantle, Ethan Dmitrovsky, Michael J. Spinella

Cancer Res. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Cancer Res. 2016 Mar 1; 76(5): 1204–1213. Published online 2016 Feb 2. doi: 10.1158/0008-5472.CAN-15-2265

PMCID:: PMC4775337

Abstract Article PDF–2.3M

Select item 45311095.

G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondria

Ping-Hsien Lee, Takeshi Yamada, Chun Shik Park, Ye Shen, Monica Puppi, H. Daniel Lacorazza

Immunol Cell Biol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Immunol Cell Biol. 2015 Aug; 93(7): 605–615. Published online 2015 Feb 10. doi: 10.1038/icb.2015.9

PMCID:: PMC4531109

Abstract Article PDF–1.6M

Select item 42074756.

G0/G1 switch gene 2 has a critical role in adipocyte differentiation

H Choi, H Lee, T-H Kim, H J Kim, Y J Lee, S J Lee, J H Yu, D Kim, K-S Kim, S W Park, J-w Kim

Cell Death Differ. 2014 Jul; 21(7): 1071–1080. Published online 2014 Feb 28. doi: 10.1038/cdd.2014.26

PMCID:: PMC4207475

Abstract Article PDF–2.8M

Select item 39314017.

Targeted Disruption of G₀/G₁ Switch Gene 2 Enhances Adipose Lipolysis, Alters Hepatic Energy Balance, and Alleviates High-Fat Diet–Induced Liver Steatosis

Xiaodong Zhang, Xitao Xie, Bradlee L. Heckmann, Alicia M. Saarinen, Traci A. Czyzyk, Jun Liu

Diabetes. 2014 Mar; 63(3): 934–946. Published online 2014 Feb 13. doi: 10.2337/db13-1422

PMCID:: PMC3931401

Abstract Article PDF–2.0M

Select item 39009418.

Defective Adipose Lipolysis and Altered Global Energy Metabolism in Mice with Adipose Overexpression of the Lipolytic Inhibitor G₀/G₁ Switch Gene 2 (G0S2)

Bradlee L. Heckmann, Xiaodong Zhang, Xitao Xie, Alicia Saarinen, Xin Lu, Xingyuan Yang, Jun Liu

J Biol Chem. 2014 Jan 24; 289(4): 1905–1916. Published online 2013 Dec 3. doi: 10.1074/jbc.M113.522011

PMCID:: PMC3900941

Abstract Article PDF–3.8M

Select item 33650169.

The Cytosolic Protein G0S2 Maintains Quiescence in Hematopoietic Stem Cells

Takeshi Yamada, Chun Shik Park, Audrea Burns, Daisuke Nakada, H. Daniel Lacorazza

PLoS One. 2012; 7(5): e38280. Published online 2012 May 31. doi: 10.1371/journal.pone.0038280

PMCID:: PMC3365016

Abstract Article PDF–2.0M

Select item 573141810.

G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer

Christina Y. Yim, Emmanuel Bikorimana, Ema Khan, Joshua M. Warzecha, Leah Shin, Jennifer Rodriguez, Ethan Dmitrovsky, Sarah J. Freemantle, Michael J. Spinella

Cell Cycle. 2017; 16(21): 2146–2155. Published online 2017 Sep 14. doi: 10.1080/15384101.2017.1371884

PMCID:: PMC5731418

Abstract Article PDF–1.2M

Select item 488906511.

Regulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL Interaction

Bradlee L. Heckmann, Xiaodong Zhang, Alicia M. Saarinen, Jun Liu

PLoS One. 2016; 11(6): e0156742. Published online 2016 Jun 1. doi: 10.1371/journal.pone.0156742

PMCID:: PMC4889065

Abstract Article PDF–2.8M

Select item 377455712.

Inverse regulation of basal lipolysis in perigonadal and mesenteric fat depots in mice

Stephan Wueest, Xingyuan Yang, Jun Liu, Eugen J. Schoenle, Daniel Konrad

Am J Physiol Endocrinol Metab. 2012 Jan 1; 302(1): E153–E160. Published online 2011 Oct 11. doi: 10.1152/ajpendo.00338.2011

PMCID:: PMC3774557

Abstract Article

Select item 365884313.

The G₀/G₁ Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase

Xingyuan Yang, Xin Lu, Marc Lombès, Geun Bae Rha, Young-In Chi, Theresa M. Guerin, Eric J. Smart, Jun Liu

Cell Metab. Author manuscript; available in PMC 2013 May 20.

Published in final edited form as: Cell Metab. 2010 Mar 3; 11(3): 194–205. doi: 10.1016/j.cmet.2010.02.003

PMCID:: PMC3658843

Abstract Article PDF–4.5M

Select item 346600014.

G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase

Martina Schweiger, Margret Paar, Christina Eder, Janina Brandis, Elena Moser, Gregor Gorkiewicz, Susanne Grond, Franz P. W. Radner, Ines Cerk, Irina Cornaciu, Monika Oberer, Sander Kersten, Rudolf Zechner, Robert Zimmermann, Achim Lass

J Lipid Res. 2012 Nov; 53(11): 2307–2317. doi: 10.1194/jlr.M027409

PMCID:: PMC3466000

Abstract Article PDF–1.2M

Select item 402608715.

Mice lacking G0S2 are lean and cold-tolerant

Tian Ma, Alexandra GN Lopez-Aguiar, Aihua Li, Yun Lu, David Sekula, Eugene E Nattie, Sarah Freemantle, Ethan Dmitrovsky

Cancer Biol Ther. 2014 May 1; 15(5): 643–650. Published online 2014 Feb 20. doi: 10.4161/cbt.28251

PMCID:: PMC4026087

Abstract Article PDF–1.6M

Select item 319845916.

The Minimal Domain of Adipose Triglyceride Lipase (ATGL) Ranges until Leucine 254 and Can Be Activated and Inhibited by CGI-58 and G0S2, Respectively

Irina Cornaciu, Andras Boeszoermenyi, Hanna Lindermuth, Harald M. Nagy, Ines K. Cerk, Catharina Ebner, Barbara Salzburger, Astrid Gruber, Martina Schweiger, Rudolf Zechner, Achim Lass, Robert Zimmermann, Monika Oberer

PLoS One. 2011; 6(10): e26349. Published online 2011 Oct 19. doi: 10.1371/journal.pone.0026349

PMCID:: PMC3198459

Abstract Article PDF–980K

Select item 131626717.

The G₀/G₁ switch gene 2 is a novel PPAR target gene

Fokko Zandbergen, Stéphane Mandard, Pascal Escher, Nguan Soon Tan, David Patsouris, Tim Jatkoe, Sandra Rojas-Caro, Steve Madore, Walter Wahli, Sherrie Tafuri, Michael Müller, Sander Kersten

Biochem J. 2005 Dec 1; 392(Pt 2): 313–324. Prepublished online 2005 Aug 9. Published online 2005 Nov 22. doi: 10.1042/BJ20050636

PMCID:: PMC1316267

Abstract Article PDF–695K

Select item 646391018.

Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G₀/G₁ switch gene 2 (G0S2)

Xiaodong Zhang, Xitao Xie, Bradlee L. Heckmann, Alicia M. Saarinen, Haiwei Gu, Rudolf Zechner, Jun Liu

FASEB J. 2019 May; 33(5): 6655–6666. Published online 2019 Feb 25. doi: 10.1096/fj.201802502R

PMCID:: PMC6463910

Abstract Article

Select item 960442819.

Mother–Fetus Immune Cross-Talk Coordinates “Extrinsic”/“Intrinsic” Embryo Gene Expression Noise and Growth Stability

Tatyana Ivanovna Babochkina, Ludmila Alekseevna Gerlinskaya, Margarita Vladimirovna Anisimova, Galina Vladimirovna Kontsevaya, Natalia Aleksandrovna Feofanova, Aliya Konstantinovna Stanova, Mikhail Pavlovich Moshkin, Yuri Mikhailovich Moshkin

Int J Mol Sci. 2022 Oct; 23(20): 12467. Published online 2022 Oct 18. doi: 10.3390/ijms232012467