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Items: 1 to 20 of 42

1.
Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking
Patrick J. Mulholland, Audrey E. Padula, Larry J. Wilhelm, Byung Park, Kathleen A. Grant, Betsy M. Ferguson, Rita Cervera-Juanes
Transl Psychiatry. 2023; 13: 364. Published online 2023 Nov 27. doi: 10.1038/s41398-023-02676-z
PMCID:
PMC10682415
AbstractArticlePDF–2.1M
2.
Bioinformatics identification and pharmacological validation of Kcnn3/KCa2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice
Audrey E. Padula, Jennifer A. Rinker, Marcelo F. Lopez, Megan K. Mulligan, Robert W. Williams, Howard C. Becker, Patrick J. Mulholland
Transl Psychiatry. 2020; 10: 414. Published online 2020 Nov 27. doi: 10.1038/s41398-020-01099-4
PMCID:
PMC7699620
AbstractArticlePDF–1.4M
3.
Down-regulation of KCa2.3 channels causes erectile dysfunction in mice
Simon Comerma-Steffensen, Attila Kun, Elise R. Hedegaard, Susie Mogensen, Christian Aalkjaer, Ralf Köhler, Birgitte Mønster Christensen, Ulf Simonsen
Sci Rep. 2017; 7: 3839. Published online 2017 Jun 19. doi: 10.1038/s41598-017-04188-5
PMCID:
PMC5476588
AbstractArticlePDF–2.7M
4.
Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure
Fui C. Yap, David S. Weber, Mark S. Taylor, Mary I. Townsley, Brian S. Comer, James Maylie, John P. Adelman, Mike T. Lin
Am J Physiol Heart Circ Physiol. 2016 May 1; 310(9): H1151–H1163. Published online 2016 Mar 4. doi: 10.1152/ajpheart.00787.2015
PMCID:
PMC4867388
AbstractArticle
5.
KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction
Audrey E Padula, William C Griffin, III, Marcelo F Lopez, Sudarat Nimitvilai, Reginald Cannady, Natalie S McGuier, Elissa J Chesler, Michael F Miles, Robert W Williams, Patrick K Randall, John J Woodward, Howard C Becker, Patrick J Mulholland
Neuropsychopharmacology. 2015 Jul; 40(8): 1928–1939. Prepublished online 2015 Feb 9. Published online 2015 Mar 4. doi: 10.1038/npp.2015.42
PMCID:
PMC4839516
AbstractArticlePDF–704K
6.
The SK3 channel promotes placental vascularization by enhancing secretion of angiogenic factors
Cara C. Rada, Grace Murray, Sarah K. England
Am J Physiol Endocrinol Metab. 2014 Nov 15; 307(10): E935–E943. Published online 2014 Sep 23. doi: 10.1152/ajpendo.00319.2014
PMCID:
PMC4315447
AbstractArticle
7.
Ovariectomy-Induced Reductions in Endothelial SK3 Channel Activity and Endothelium-Dependent Vasorelaxation in Murine Mesenteric Arteries
Fui C. Yap, Mark S. Taylor, Mike T. Lin
PLoS One. 2014; 9(8): e104686. Published online 2014 Aug 8. doi: 10.1371/journal.pone.0104686
PMCID:
PMC4126749
AbstractArticlePDF–1.8M
8.
Overexpression of KCNN3 results in sudden cardiac death
Saagar Mahida, Robert W. Mills, Nathan R. Tucker, Bridget Simonson, Vincenzo Macri, Marc D. Lemoine, Saumya Das, David J. Milan, Patrick T. Ellinor
Cardiovasc Res. 2014 Feb 1; 101(2): 326–334. Published online 2013 Dec 1. doi: 10.1093/cvr/cvt269
PMCID:
PMC3896252
AbstractArticlePDF–495K
9.
Critical roles of a small conductance Ca2+-activated K+ channel (SK3) in the repolarization process of atrial myocytes
Xiao-Dong Zhang, Valeriy Timofeyev, Ning Li, Richard E. Myers, Dai-Min Zhang, Anil Singapuri, Victor C. Lau, Chris T. Bond, John Adelman, Deborah K. Lieu, Nipavan Chiamvimonvat
Cardiovasc Res. 2014 Feb 1; 101(2): 317–325. Published online 2013 Nov 26. doi: 10.1093/cvr/cvt262
PMCID:
PMC3896251
AbstractArticlePDF–543K
10.
Activation of KCNN3/SK3/KCa2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia
Amalia M. Dolga, Till Letsche, Maike Gold, Nunzianna Doti, Michael Bacher, Nipavan Chiamvimonvat, Richard Dodel, Carsten Culmsee
Glia. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: Glia. 2012 Dec; 60(12): 2050–2064. Published online 2012 Sep 21. doi: 10.1002/glia.22419
PMCID:
PMC3799773
AbstractArticlePDF–1.5M
11.
Overexpression of the SK3 channel alters vascular remodeling during pregnancy, leading to fetal demise
Cara C. Rada, Stephanie L. Pierce, Daniel W. Nuno, Kathy Zimmerman, Kathryn G. Lamping, Noelle C. Bowdler, Robert M. Weiss, Sarah K. England
Am J Physiol Endocrinol Metab. 2012 Oct 1; 303(7): E825–E831. Published online 2012 Jul 11. doi: 10.1152/ajpendo.00165.2012
PMCID:
PMC3469615
AbstractArticle
12.
In vivo measurement of intrauterine pressure by telemetry: a new approach for studying parturition in mouse models
Stephanie L. Pierce, William Kutschke, Rafael Cabeza, Sarah K. England
Physiol Genomics. 2010 Jul; 42(2): 310–316. Published online 2010 May 11. doi: 10.1152/physiolgenomics.00058.2010
PMCID:
PMC3032287
AbstractArticle
13.
SK3 channel expression during pregnancy is regulated through estrogen and Sp factor-mediated transcriptional control of the KCNN3 gene
Stephanie L. Pierce, Sarah K. England
Am J Physiol Endocrinol Metab. 2010 Oct; 299(4): E640–E646. Published online 2010 Aug 3. doi: 10.1152/ajpendo.00063.2010
PMCID:
PMC2957868
AbstractArticle
14.
Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel
Gerald M Herrera, Maria J Pozo, Peter Zvara, Georgi V Petkov, Chris T Bond, John P Adelman, Mark T Nelson
J Physiol. 2003 Sep 15; 551(Pt 3): 893–903. Published online 2003 Jun 17. doi: 10.1113/jphysiol.2003.045914
PMCID:
PMC2343290
AbstractArticlePDF–1.5M
15.
Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels
Derya Sargin, David K Oliver, Evelyn K Lambe
eLife. 2016; 5: e21416. Published online 2016 Nov 22. doi: 10.7554/eLife.21416
PMCID:
PMC5119885
AbstractArticlePDF–1.6M
16.
Down-regulation of the Small Conductance Calcium-activated Potassium Channels in Diabetic Mouse Atria
Fu Yi, Tian-You Ling, Tong Lu, Xiao-Li Wang, Jingchao Li, William C. Claycomb, Win-Kuang Shen, Hon-Chi Lee
J Biol Chem. 2015 Mar 13; 290(11): 7016–7026. Published online 2015 Jan 20. doi: 10.1074/jbc.M114.607952
PMCID:
PMC4358125
AbstractArticlePDF–2.2M
17.
Pulmonary Hypertension in Wild Type Mice and Animals with Genetic Deficit in KCa2.3 and KCa3.1 Channels
Christine Wandall-Frostholm, Lykke Moran Skaarup, Veeranjaneyulu Sadda, Gorm Nielsen, Elise Røge Hedegaard, Susie Mogensen, Ralf Köhler, Ulf Simonsen
PLoS One. 2014; 9(5): e97687. Published online 2014 May 23. doi: 10.1371/journal.pone.0097687
PMCID:
PMC4032241
AbstractArticlePDF–1.1M
18.
Emerging Role of the Calcium-Activated, Small Conductance, SK3 K+ Channel in Distal Tubule Function: Regulation by TRPV4
Jonathan Berrout, Mykola Mamenko, Oleg L. Zaika, Lihe Chen, Wenzheng Zang, Oleh Pochynyuk, Roger G. O'Neil
PLoS One. 2014; 9(4): e95149. Published online 2014 Apr 24. doi: 10.1371/journal.pone.0095149
Correction in:
PLoS One. 2016; 11(5): e0156368.
PMCID:
PMC3999037
AbstractArticlePDF–8.5M
19.
Modulation of endothelial SK3 channel activity by Ca2+-dependent caveolar trafficking
Mike T. Lin, John P. Adelman, James Maylie
Am J Physiol Cell Physiol. 2012 Aug 1; 303(3): C318–C327. Published online 2012 May 23. doi: 10.1152/ajpcell.00058.2012
PMCID:
PMC3423019
AbstractArticle
20.
SK2 and SK3 Expression Differentially Affect Firing Frequency and Precision in Dopamine Neurons
Jason Deignan, Rafael Luján, Chris Bond, Arthur Riegel, Masahiko Watanabe, John T. Williams, James Maylie, John P. Adelman
Neuroscience. Author manuscript; available in PMC 2013 Aug 16.
Published in final edited form as: Neuroscience. 2012 Aug 16; 217: 67–76. Published online 2012 Apr 30. doi: 10.1016/j.neuroscience.2012.04.053
PMCID:
PMC3383402
AbstractArticlePDF–791K

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