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Select item 108648681.

NR2F6 is essential for brown adipocyte differentiation and systemic metabolic homeostasis

Wei-yu Zhou, Pei Liu, Yi-fan Xia, Yi-jie Shi, Hong-yu Xu, Meng Ding, Qi-qi Yang, Shu-wen Qian, Yan Tang, Yan Lu, Qi-qun Tang, Yang Liu

Mol Metab. 2024 Mar; 81: 101891. Published online 2024 Feb 1. doi: 10.1016/j.molmet.2024.101891

PMCID:: PMC10864868

Abstract Article PDF–2.6M

Select item 103217532.

Melanoma-intrinsic NR2F6 activity regulates antitumor immunity

Hyungsoo Kim, Yongmei Feng, Rabi Murad, Joanna Pozniak, Carl Pelz, Yeqing Chen, Bhavik Dalal, Rosalie Sears, Eduard Sergienko, Michael Jackson, Eytan Ruppin, Meenhard Herlyn, Curtis Harris, Jean-Christophe Marine, Victoria Klepsch, Gottfried Baier, Ze’ev A. Ronai

Sci Adv. 2023 Jul; 9(27): eadf6621. Published online 2023 Jul 5. doi: 10.1126/sciadv.adf6621

PMCID:: PMC10321753

Abstract Article PDF–2.0M

Select item 94251123.

A role for the nuclear receptor NR2F6 in peritoneal B cell homeostasis

William J. Olson, Bojana Jakic, Verena Labi, Johannes Woelk, Emmanuel Derudder, Gottfried Baier, Natascha Hermann-Kleiter

Front Immunol. 2022; 13: 845235. Published online 2022 Aug 16. doi: 10.3389/fimmu.2022.845235

PMCID:: PMC9425112

Abstract Article PDF–7.1M

Select item 78844264.

Loss of the orphan nuclear receptor NR2F6 enhances CD8⁺ T-cell memory via IFN-γ

Bojana Jakic, William J. Olson, Kerstin Siegmund, Victoria Klepsch, Janine Kimpel, Verena Labi, Dietmar Zehn, Gottfried Baier, Natascha Hermann-Kleiter

Cell Death Dis. 2021 Feb; 12(2): 187. Published online 2021 Feb 15. doi: 10.1038/s41419-021-03470-9

PMCID:: PMC7884426

Abstract Article PDF–3.5M

Select item 69613685.

Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy

Victoria Klepsch, Maria Pommermayr, Dominik Humer, Natascha Brigo, Natascha Hermann-Kleiter, Gottfried Baier

Cell Commun Signal. 2020; 18: 8. Published online 2020 Jan 14. doi: 10.1186/s12964-019-0454-z

PMCID:: PMC6961368

Abstract Article PDF–1.9M

Select item 67918126.

Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21

William J. Olson, Bojana Jakic, Verena Labi, Katia Schoeler, Michaela Kind, Victoria Klepsch, Gottfried Baier, Natascha Hermann-Kleiter

Cell Rep. 2019 Sep 10; 28(11): 2878–2891.e5. Published online 2019 Sep 10. doi: 10.1016/j.celrep.2019.08.024

PMCID:: PMC6791812

Abstract Article

Select item 45941577.

The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance

Natascha Hermann-Kleiter, Victoria Klepsch, Stephanie Wallner, Kerstin Siegmund, Sebastian Klepsch, Selma Tuzlak, Andreas Villunger, Sandra Kaminski, Christa Pfeifhofer-Obermair, Thomas Gruber, Dominik Wolf, Gottfried Baier

Cell Rep. 2015 Sep 29; 12(12): 2072–2085. Published online 2015 Sep 17. doi: 10.1016/j.celrep.2015.08.035

PMCID:: PMC4594157

Abstract Article

Select item 110742638.

Trefoil factor 3 can stimulate Th17 cell response in the development of type 2 diabetes mellitus

Ziyang Lin, Jinyuan Zhang, Tingting Duan, Junzheng Yang, Yiqi Yang

Sci Rep. 2024; 14: 10340. Published online 2024 May 6. doi: 10.1038/s41598-024-60426-7

PMCID:: PMC11074263

Abstract Article PDF–4.5M

Select item 59066049.

Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

Victoria Klepsch, Natascha Hermann-Kleiter, Patricia Do-Dinh, Bojana Jakic, Anne Offermann, Mirjana Efremova, Sieghart Sopper, Dietmar Rieder, Anne Krogsdam, Gabriele Gamerith, Sven Perner, Alexandar Tzankov, Zlatko Trajanoski, Dominik Wolf, Gottfried Baier

Nat Commun. 2018; 9: 1538. Published online 2018 Apr 18. doi: 10.1038/s41467-018-04004-2

PMCID:: PMC5906604

Abstract Article PDF–1.8M

Select item 414762610.

Ear2 Deletion Causes Early Memory and Learning Deficits in APP/PS1 Mice

Markus P. Kummer, Thea Hammerschmidt, Ana Martinez, Dick Terwel, Gregor Eichele, Anika Witten, Stefanie Figura, Monika Stoll, Stephanie Schwartz, Hans-Christian Pape, Joachim L. Schultze, David Weinshenker, Michael T. Heneka

J Neurosci. 2014 Jun 25; 34(26): 8845–8854. doi: 10.1523/JNEUROSCI.4027-13.2014

Correction in:: J Neurosci. 2015 Feb 4; 35(5): 2321.

PMCID:: PMC4147626

Abstract Article PDF–3.0M

Select item 351670711.

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter

Natascha Hermann-Kleiter, Marlies Meisel, Friedrich Fresser, Nikolaus Thuille, Mathias Müller, Lukas Roth, Andreas Katopodis, Gottfried Baier

J Autoimmun. 2012 Dec; 39(4): 428–440. doi: 10.1016/j.jaut.2012.07.007

PMCID:: PMC3516707

Abstract Article

Select item 494192612.

The Nuclear Orphan Receptor NR2F6 Suppresses Lymphocyte Activation and T Helper 17-Dependent Autoimmunity

Natascha Hermann-Kleiter, Thomas Gruber, Christina Lutz-Nicoladoni, Nikolaus Thuille, Friedrich Fresser, Verena Labi, Natalia Schiefermeier, Marei Warnecke, Lukas Huber, Andreas Villunger, Gregor Eichele, Sandra Kaminski, Gottfried Baier

Immunity. Author manuscript; available in PMC 2016 Jul 12.

Published in final edited form as: Immunity. 2008 Aug 15; 29(2): 205–216. doi: 10.1016/j.immuni.2008.06.008

PMCID:: PMC4941926

Abstract Article PDF–2.0M

Select item 435002713.

A Proteomic Analysis Reveals That Snail Regulates the Expression of the Nuclear Orphan Receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and Interleukin 17 (IL-17) to Inhibit Adipocyte Differentiation

Alberto Peláez-García, Rodrigo Barderas, Raquel Batlle, Rosa Viñas-Castells, Rubén A. Bartolomé, Sofía Torres, Marta Mendes, María Lopez-Lucendo, Rocco Mazzolini, Félix Bonilla, Antonio García de Herreros, J. Ignacio Casal

Mol Cell Proteomics. 2015 Feb; 14(2): 303–315. Published online 2014 Dec 10. doi: 10.1074/mcp.M114.045328

PMCID:: PMC4350027

Abstract Article PDF–2.7M

Select item 333071614.

Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6

Eric T. Weatherford, Xuebo Liu, Curt D. Sigmund

Am J Physiol Renal Physiol. 2012 Apr 15; 302(8): F1025–F1033. Published online 2012 Jan 25. doi: 10.1152/ajprenal.00362.2011

PMCID:: PMC3330716

Abstract Article

Select item 303662115.

Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription

Jen Jen Tan, Shufen Angeline Ong, Ken-Shiung Chen

BMC Mol Biol. 2011; 12: 4. Published online 2011 Jan 19. doi: 10.1186/1471-2199-12-4

PMCID:: PMC3036621

Abstract Article PDF–1.9M

Select item 55158116.

Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception

Marei Warnecke, Henrik Oster, Jean-Pierre Revelli, Gonzalo Alvarez-Bolado, Gregor Eichele

Genes Dev. 2005 Mar 1; 19(5): 614–625. doi: 10.1101/gad.317905

PMCID:: PMC551581

Abstract Article PDF–1.1M

Select item 264992217.

Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain

David Chambers, Leigh Jane Wilson, Fabienne Alfonsi, Ewan Hunter, Uma Saxena, Eric Blanc, Andrew Lumsden

Neural Dev. 2009; 4: 6. Published online 2009 Feb 10. doi: 10.1186/1749-8104-4-6

PMCID:: PMC2649922

Abstract Article PDF–1.0M

Select item 383482918.

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors

Chun Ming Chan, Joel Fulton, Cristina Montiel-Duarte, Hilary M. Collins, Neetu Bharti, Frances R. Wadelin, Paula M. Moran, Nigel P. Mongan, David M. Heery

Nucleic Acids Res. 2013 Nov; 41(21): 9663–9679. Published online 2013 Aug 23. doi: 10.1093/nar/gkt761

PMCID:: PMC3834829

Abstract Article PDF–3.7M

Select item 274831319.

High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population

Joshua W. Mugford, Jing Yu, Akio Kobayashi, Andrew P. McMahon

Dev Biol. Author manuscript; available in PMC 2010 Sep 15.

Published in final edited form as: Dev Biol. 2009 Sep 15; 333(2): 312–323. Published online 2009 Jul 8. doi: 10.1016/j.ydbio.2009.06.043

PMCID:: PMC2748313

Abstract Article PDF–5.4M

Select item 248143120.

Identification of transcripts with enriched expression in the developing and adult pancreas

Brad G Hoffman, Bogard Zavaglia, Joy Witzsche, Teresa Ruiz de Algara, Mike Beach, Pamela A Hoodless, Steven JM Jones, Marco A Marra, Cheryl D Helgason

Genome Biol. 2008; 9(6): R99. Published online 2008 Jun 14. doi: 10.1186/gb-2008-9-6-r99