PMC Links for Gene (Select 1358) - PMC

Select item 37644241.

High-resolution Structural and Thermodynamic Analysis of Extreme Stabilization of Human Procarboxypeptidase by Computational Protein Design

Gautam Dantas, Colin Corrent, Steve L. Reichow, James J. Havranek, Ziad M. Eletr, Nancy G. Isern, Brian Kuhlman, Gabriele Varani, Ethan A. Merritt, David Baker

J Mol Biol. 2007 Mar 2; 366(4): 1209–1221. doi: 10.1016/j.jmb.2006.11.080

PMCID:: PMC3764424

Abstract Article

Select item 23124172.

NMR solution structure of the activation domain of human procarboxypeptidase A2

M. Angeles Jiménez, Virtudes Villegas, Jorge Santoro, Luis Serrano, Josep Vendrell, Francesc X. Avilés, Manuel Rico

Protein Sci. 2003 Feb; 12(2): 296–305. doi: 10.1110/ps.0227303

PMCID:: PMC2312417

Abstract Article PDF–277K

Select item 11702943.

The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.

I García-Sáez, D Reverter, J Vendrell, F X Avilés, M Coll

EMBO J. 1997 Dec 1; 16(23): 6906–6913. doi: 10.1093/emboj/16.23.6906

PMCID:: PMC1170294

Summary PDF–433K

Select item 46099304.

Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis

Eriko Nakano, Andrea Geisz, Atsushi Masamune, Tetsuya Niihori, Shin Hamada, Kiyoshi Kume, Yoichi Kakuta, Yoko Aoki, Yoichi Matsubara, Karolin Ebert, Maren Ludwig, Markus Braun, David A. Groneberg, Tooru Shimosegawa, Miklós Sahin-Tóth, Heiko Witt

Am J Physiol Gastrointest Liver Physiol. 2015 Oct 15; 309(8): G688–G694. Published online 2015 Aug 27. doi: 10.1152/ajpgi.00241.2015

PMCID:: PMC4609930

Abstract Article

Select item 30234775.

Chymotrypsin C Is a Co-activator of Human Pancreatic Procarboxypeptidases A1 and A2

Richárd Szmola, Melinda Bence, Andrea Carpentieri, András Szabó, Catherine E. Costello, John Samuelson, Miklós Sahin-Tóth

J Biol Chem. 2011 Jan 21; 286(3): 1819–1827. Published online 2010 Nov 22. doi: 10.1074/jbc.M110.187369

PMCID:: PMC3023477

Abstract Article PDF–1.3M

Select item 28817646.

Characterization of the Substrate Specificity of Human Carboxypeptidase A4 and Implications for a Role in Extracellular Peptide Processing

Sebastian Tanco, Xin Zhang, Cain Morano, Francesc Xavier Avilés, Julia Lorenzo, Lloyd D. Fricker

J Biol Chem. 2010 Jun 11; 285(24): 18385–18396. Published online 2010 Apr 12. doi: 10.1074/jbc.M109.060350

PMCID:: PMC2881764

Abstract Article PDF–1.7M

Select item 50161657.

Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2

András Szabó, Claudia Pilsak, Melinda Bence, Heiko Witt, Miklós Sahin-Tóth

J Biol Chem. 2016 Aug 19; 291(34): 17706–17716. Published online 2016 Jun 29. doi: 10.1074/jbc.M116.743237

PMCID:: PMC5016165

Abstract Article PDF–1.5M

Select item 29347398.

High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L–DOCK4 gene region in autism susceptibility

E Maestrini, A T Pagnamenta, J A Lamb, E Bacchelli, N H Sykes, I Sousa, C Toma, G Barnby, H Butler, L Winchester, T S Scerri, F Minopoli, J Reichert, G Cai, J D Buxbaum, O Korvatska, G D Schellenberg, G Dawson, A de Bildt, R B Minderaa, E J Mulder, A P Morris, A J Bailey, A P Monaco, IMGSAC

Mol Psychiatry. 2010 Sep; 15(9): 954–968. Published online 2009 Apr 28. doi: 10.1038/mp.2009.34

PMCID:: PMC2934739

Abstract Article PDF–376K

Select item 48821909.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 289646410.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011