PMC Links for Gene (Select 12780) - PMC

Alper Okyar, Enza Piccolo, Constance Ahowesso, Elisabeth Filipski, Virginie Hossard, Catherine Guettier, Rosanna La Sorda, Nicola Tinari, Stefano Iacobelli, Francis Lévi

PLoS One. 2011; 6(6): e20393. Published online 2011 Jun 3. doi: 10.1371/journal.pone.0020393

PMCID:: PMC3108586

Abstract Article PDF–566K

Select item 28470154.

Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2)

Kirill Tsirulnikov, Natalia Abuladze, Myong-Chul Koag, Debra Newman, Karoline Scholz, Galyna Bondar, Quansheng Zhu, Nuraly K. Avliyakulov, Wolfgang Dekant, Kym Faull, Ira Kurtz, Alexander Pushkin

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2011 Apr 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2010 Apr 15; 244(2): 218–225. Published online 2010 Jan 6. doi: 10.1016/j.taap.2009.12.035

PMCID:: PMC2847015

Abstract Article PDF–791K

Select item 74031535.

Reduced Mrp2 surface availability as PI3Kγ-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsis

Anne J. Beer, David Hertz, Eric Seemann, Martina Beretta, Martin Westermann, Reinhard Bauer, Michael Bauer, Michael M. Kessels, Britta Qualmann

Sci Rep. 2020; 10: 13110. Published online 2020 Aug 4. doi: 10.1038/s41598-020-69901-3

PMCID:: PMC7403153

Abstract Article PDF–7.0M

Select item 60340766.

Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection

Andrew Zukauskas, Randall J. Mrsny, Paula Cortés Barrantes, Jerrold R. Turner, John M. Leong, Beth A. McCormick

mSphere. 2018 Jul-Aug; 3(4): e00303-18. Published online 2018 Jul 5. doi: 10.1128/mSphere.00303-18

PMCID:: PMC6034076

Abstract Article PDF–1.0M

Select item 45198237.

Dependence of erythromycin metabolism on ABCC2 (MRP2) transport function

RM Franke, CS Lancaster, CJ Peer, A Gibson, AM Kosloske, SJ Orwick, RH Mathijssen, WD Figg, SD Baker, A Sparreboom

Clin Pharmacol Ther. Author manuscript; available in PMC 2015 Jul 30.

Published in final edited form as: Clin Pharmacol Ther. 2011 May; 89(5): 693–701. Published online 2011 Mar 30. doi: 10.1038/clpt.2011.25

PMCID:: PMC4519823

Abstract Article PDF–1.0M

Select item 40059898.

Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice

Xia Wen, Brian Buckley, Elizabeth McCandlish, Michael J. Goedken, Samira Syed, Ryan Pelis, José E. Manautou, Lauren M. Aleksunes

Am J Pathol. 2014 May; 184(5): 1299–1308. doi: 10.1016/j.ajpath.2014.01.025

PMCID:: PMC4005989

Abstract Article PDF–2.1M

Select item 35548419.

Metallothionein blocks oxidative DNA damage in vitro

Wei Qu, Jingbo Pi, Michael P. Waalkes

Arch Toxicol. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Arch Toxicol. 2013 Feb; 87(2): 311–321. Published online 2012 Aug 23. doi: 10.1007/s00204-012-0927-y

PMCID:: PMC3554841

Abstract Article PDF–1.9M

Select item 319890010.

Dose-Dependent Disposition of Methotrexate in Abcc2 and Abcc3 Gene Knockout Murine Models

Zhan Wang, Qingyu Zhou, Gary D. Kruh, James M. Gallo

Drug Metab Dispos. 2011 Nov; 39(11): 2155–2161. doi: 10.1124/dmd.111.041228

PMCID:: PMC3198900

Abstract Article PDF–789K

Select item 259666211.

Multi-Drug Resistance Transporter 2 Regulates Mucosal Inflammation by Facilitating the Synthesis of Hepoxilin A₃

Michael Pazos, Dario Siccardi, Karen L. Mumy, Jeffrey D. Bien, Steve Louie, Hai Ning Shi, Karsten Gronert, Randall J. Mrsny, Beth A. McCormick

J Immunol. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: J Immunol. 2008 Dec 1; 181(11): 8044–8052. doi: 10.4049/jimmunol.181.11.8044

PMCID:: PMC2596662

Abstract Article PDF–2.3M

Select item 528389812.

CFTR-associated ligand is a negative regulator of Mrp2 expression

Man Li, Carol J. Soroka, Kathy Harry, James L. Boyer

Am J Physiol Cell Physiol. 2017 Jan 1; 312(1): C40–C46. Published online 2016 Nov 9. doi: 10.1152/ajpcell.00100.2016

PMCID:: PMC5283898

Abstract Article

Select item 449002813.

Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide is Dependent on Abcc2, Abcc3, and Oatp1a/1b

Aksana Vasilyeva, Selvi Durmus, Lie Li, Els Wagenaar, Shuiying Hu, Alice A. Gibson, John C. Panetta, Sridhar Mani, Alex Sparreboom, Sharyn D. Baker, Alfred H. Schinkel

Cancer Res. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Cancer Res. 2015 Jul 1; 75(13): 2729–2736. Published online 2015 May 7. doi: 10.1158/0008-5472.CAN-15-0280

PMCID:: PMC4490028

Abstract Article PDF–2.2M

Select item 146268414.

Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene

Valeska Vollrath, Ana M. Wielandt, Mirentxu Iruretagoyena, Jose Chianale

Biochem J. 2006 May 1; 395(Pt 3): 599–609. Prepublished online 2006 Jan 23. Published online 2006 Apr 11. doi: 10.1042/BJ20051518

PMCID:: PMC1462684

Abstract Article PDF–1.0M

Select item 266511815.

Activity of the Bile Salt Export Pump (ABCB11) Is Critically Dependent on Canalicular Membrane Cholesterol Content

Coen C. Paulusma, D. Rudi de Waart, Cindy Kunne, Kam S. Mok, Ronald P. J. Oude Elferink

J Biol Chem. 2009 Apr 10; 284(15): 9947–9954. doi: 10.1074/jbc.M808667200

PMCID:: PMC2665118

Abstract Article PDF–601K

Select item 354363216.

The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis

Nathan J. Cherrington, Teresa E. Estrada, Harrison A. Frisk, Mark J. Canet, Rhiannon N. Hardwick, Bohuslav Dvorak, Katie Lux, Melissa D. Halpern

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1; 304(1): G48–G56. Published online 2012 Nov 1. doi: 10.1152/ajpgi.00317.2012

PMCID:: PMC3543632

Abstract Article

Select item 326679017.

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver

Evita van de Steeg, Viktor Stránecký, Hana Hartmannová, Lenka Nosková, Martin Hřebíček, Els Wagenaar, Anita van Esch, Dirk R. de Waart, Ronald P.J. Oude Elferink, Kathryn E. Kenworthy, Eva Sticová, Mohammad al-Edreesi, A.S. Knisely, Stanislav Kmoch, Milan Jirsa, Alfred H. Schinkel

J Clin Invest. 2012 Feb 1; 122(2): 519–528. Published online 2012 Jan 9. doi: 10.1172/JCI59526

PMCID:: PMC3266790

Abstract Article PDF–1.1M

Select item 324793618.

The Src Family Kinase Fyn Mediates Hyperosmolarity-induced Mrp2 and Bsep Retrieval from Canalicular Membrane

Miriam Cantore, Roland Reinehr, Annika Sommerfeld, Martin Becker, Dieter Häussinger

J Biol Chem. 2011 Dec 30; 286(52): 45014–45029. Published online 2011 Nov 4. doi: 10.1074/jbc.M111.292896

PMCID:: PMC3247936

Abstract Article PDF–5.4M

Select item 288520819.

NHERF-1 Binds to Mrp2 and Regulates Hepatic Mrp2 Expression and Function

Man Li, Wei Wang, Carol J. Soroka, Albert Mennone, Kathy Harry, Edward J. Weinman, James L. Boyer

J Biol Chem. 2010 Jun 18; 285(25): 19299–19307. Published online 2010 Apr 19. doi: 10.1074/jbc.M109.096081

PMCID:: PMC2885208

Abstract Article PDF–1.8M

Select item 459835620.

Maternal bile acid transporter deficiency promotes neonatal demise

Yuanyuan Zhang, Fei Li, Yao Wang, Aaron Pitre, Zhong-ze Fang, Matthew W. Frank, Christopher Calabrese, Kristopher W. Krausz, Geoffrey Neale, Sharon Frase, Peter Vogel, Charles O. Rock, Frank J. Gonzalez, John D. Schuetz

Nat Commun. 2015; 6: 8186. Published online 2015 Sep 29. doi: 10.1038/ncomms9186

PMCID:: PMC4598356

Abstract Article PDF–1.5M

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