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Select item 101621361.

p35 is a Crucial Player in NK-cell Cytotoxicity and TGFβ-mediated NK-cell Dysfunction

Derek P. Wong, Claire E. Fritz, Daniel Feinberg, Alex Y. Huang, Reshmi Parameswaran

Cancer Res Commun. 2023 May; 3(5): 793–806. Published online 2023 May 5. doi: 10.1158/2767-9764.CRC-22-0497

PMCID:: PMC10162136

Abstract Article PDF–15M

Select item 90525172.

Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons

Miyuki Takahashi, Takeru Nakabayashi, Naoki Mita, Xiaohua Jin, Yuta Aikawa, Kodai Sasamoto, Goichi Miyoshi, Mariko Miyata, Takafumi Inoue, Toshio Ohshima

Mol Brain. 2022; 15: 37. Published online 2022 Apr 28. doi: 10.1186/s13041-022-00922-x

PMCID:: PMC9052517

Abstract Article PDF–1.1M

Select item 67623163.

Abnormal Morphological and Functional Organization of the Hippocampus in a p35 Mutant Model of Cortical Dysplasia Associated with Spontaneous Seizures

H. J. Wenzel, C. A. Robbins, L.-H. Tsai, P. A. Schwartzkroin

J Neurosci. 2001 Feb 1; 21(3): 983–998. doi: 10.1523/JNEUROSCI.21-03-00983.2001

PMCID:: PMC6762316

Abstract Article PDF–2.4M

Select item 67421104.

Partial Rescue of the p35−/− Brain Phenotype by Low Expression of a Neuronal-Specific Enolase p25 Transgene

Holger Patzke, Upendra Maddineni, Ramses Ayala, Maria Morabito, Janet Volker, Pieter Dikkes, Michael K. Ahlijanian, Li-Huei Tsai

J Neurosci. 2003 Apr 1; 23(7): 2769–2778. doi: 10.1523/JNEUROSCI.23-07-02769.2003

PMCID:: PMC6742110

Abstract Article PDF–576K

Select item 67300675.

Physiological and Morphological Characterization of Dentate Granule Cells in the p35 Knock-Out Mouse Hippocampus: Evidence for an Epileptic Circuit

Leena S. Patel, H. Jürgen Wenzel, Philip A. Schwartzkroin

J Neurosci. 2004 Oct 13; 24(41): 9005–9014. doi: 10.1523/JNEUROSCI.2943-04.2004

PMCID:: PMC6730067

Abstract Article PDF–525K

Select item 67299846.

Control of Cortical Neuron Migration and Layering: Cell and Non Cell-Autonomous Effects of p35

Vicki Hammond, Li-Huei Tsai, Seong-Seng Tan

J Neurosci. 2004 Jan 14; 24(2): 576–587. doi: 10.1523/JNEUROSCI.4529-03.2004

PMCID:: PMC6729984

Abstract Article PDF–2.0M

Select item 66211367.

Cdk5/p25-Induced Cytosolic PLA2-Mediated Lysophosphatidylcholine Production Regulates Neuroinflammation and Triggers Neurodegeneration

Jeyapriya R. Sundaram, Elizabeth S. Chan, Charlene P. Poore, Tej K. Pareek, Wei Fun Cheong, Guanghou Shui, Ning Tang, Chian-Ming Low, Markus R. Wenk, Sashi Kesavapany

J Neurosci. 2012 Jan 18; 32(3): 1020–1034. doi: 10.1523/JNEUROSCI.5177-11.2012

PMCID:: PMC6621136

Abstract Article PDF–7.5M

Select item 59665818.

Inducible Knockout of the Cyclin-Dependent Kinase 5 Activator p35 Alters Hippocampal Spatial Coding and Neuronal Excitability

Eriko Kamiki, Roman Boehringer, Denis Polygalov, Toshio Ohshima, Thomas J. McHugh

Front Cell Neurosci. 2018; 12: 138. Published online 2018 May 17. doi: 10.3389/fncel.2018.00138

PMCID:: PMC5966581

Abstract Article PDF–2.0M

Select item 56371189.

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia

Jinsoo Seo, Oleg Kritskiy, L. Ashley Watson, Scarlett J. Barker, Dilip Dey, Waseem K. Raja, Yuan-Ta Lin, Tak Ko, Sukhee Cho, Jay Penney, M. Catarina Silva, Steven D. Sheridan, Diane Lucente, James F. Gusella, Bradford C. Dickerson, Stephen J. Haggarty, Li-Huei Tsai

J Neurosci. 2017 Oct 11; 37(41): 9917–9924. doi: 10.1523/JNEUROSCI.0621-17.2017

PMCID:: PMC5637118

Abstract Article PDF–1.5M

Select item 446674110.

Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway

Damien Rei, Xenos Mason, Jinsoo Seo, Johannes Gräff, Andrii Rudenko, Jun Wang, Richard Rueda, Sandra Siegert, Sukhee Cho, Rebecca G. Canter, Alison E. Mungenast, Karl Deisseroth, Li-Huei Tsai

Proc Natl Acad Sci U S A. 2015 Jun 9; 112(23): 7291–7296. Published online 2015 May 20. doi: 10.1073/pnas.1415845112

PMCID:: PMC4466741

Abstract Article PDF–1.4M

Select item 386491111.

Decreasing Levels of the cdk5 Activators, p25 and p35, Reduces Excitotoxicity in Striatal Neurons

Kevin H.J. Park, Ge Lu, Jing Fan, Lynn A. Raymond, Blair R. Leavitt

J Huntingtons Dis. Author manuscript; available in PMC 2013 Dec 16.

Published in final edited form as: J Huntingtons Dis. 2012; 1(1): 10.3233/JHD-2012-129000. Published online 2012 Jun 6. doi: 10.3233/JHD-2012-129000

PMCID:: PMC3864911

Abstract Article PDF–754K

Select item 297548312.

Role of a cdk5-associated protein, p35, in herpes simplex virus type 1 replication in vivo

Steve D Haenchen, Jeff A Utter, Adam M Bayless, Rick T Dobrowsky, David J Davido

J Neurovirol. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: J Neurovirol. 2010 Oct; 16(5): 405–409. doi: 10.3109/13550284.2010.513030

PMCID:: PMC2975483

Abstract Article PDF–101K

Select item 281842613.

Essential Role of Cytoplasmic cdk5 and Prx2 in Multiple Ischemic Injury Models, In Vivo

Juliet Rashidian, Maxime W. Rousseaux, Katerina Venderova, Dianbo Qu, Steve M. Callaghan, Maryam Phillips, Ross J. Bland, Matthew J. During, Zixu Mao, Ruth S. Slack, David S. Park

J Neurosci. 2009 Oct 7; 29(40): 12497–12505. doi: 10.1523/JNEUROSCI.3892-09.2009

PMCID:: PMC2818426

Abstract Article PDF–1.2M

Select item 911592214.

Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition

Doo Soon Im, Alvin Joselin, Devon Svoboda, Tesuya Takano, Maxime W. C. Rousseaux, Steve Callaghan, Ruth S. Slack, Shin-ichi Hisanaga, Roger J. Davis, David S. Park, Dianbo Qu

BMC Biol. 2022; 20: 115. Published online 2022 May 17. doi: 10.1186/s12915-022-01312-4

PMCID:: PMC9115922

Abstract Article PDF–5.3M

Select item 785314515.

RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation

Dongdong Zhao, Yunqiang Zhou, Yuanhui Huo, Jian Meng, Xiaoxia Xiao, Linkun Han, Xian Zhang, Hong Luo, Dan Can, Hao Sun, Timothy Y. Huang, Xin Wang, Jie Zhang, Fa-rong Liu, Huaxi Xu, Yun-wu Zhang

Cell Death Differ. 2021 Jan; 28(1): 337–348. Published online 2020 Sep 9. doi: 10.1038/s41418-020-00620-y

PMCID:: PMC7853145

Abstract Article PDF–3.9M

Select item 674091816.

Decreased Cyclin-Dependent Kinase 5 (cdk5) Activity Is Accompanied by Redistribution of cdk5 and Cytoskeletal Proteins and Increased Cytoskeletal Protein Phosphorylation in p35 Null Mice

Janice L. Hallows, Ken Chen, Ronald A. DePinho, Inez Vincent

J Neurosci. 2003 Nov 19; 23(33): 10633–10644. doi: 10.1523/JNEUROSCI.23-33-10633.2003

PMCID:: PMC6740918

Abstract Article PDF–1.6M

Select item 667516817.

p35/p25 Is Not Essential for Tau and Cytoskeletal Pathology or Neuronal Loss in Niemann–Pick Type C Disease

Janice L. Hallows, Robert E. Iosif, Rebecca D. Biasell, Inez Vincent

J Neurosci. 2006 Mar 8; 26(10): 2738–2744. doi: 10.1523/JNEUROSCI.4834-05.2006

PMCID:: PMC6675168

Abstract Article PDF–354K

Select item 643495018.

Neuron-specific menin deletion leads to synaptic dysfunction and cognitive impairment by modulating p35 expression

Kai Zhuang, Changquan Huang, Lige Leng, Honghua Zheng, Yuehong Gao, Guimiao Chen, Zhilin Ji, Hao Sun, Yu Hu, Di Wu, Meng Shi, Huifang Li, Yingjun Zhao, Yunwu Zhang, Maoqiang Xue, Guojun Bu, Timothy Y. Huang, Huaxi Xu, Jie Zhang

Cell Rep. Author manuscript; available in PMC 2019 Mar 26.

Published in final edited form as: Cell Rep. 2018 Jul 17; 24(3): 701–712. doi: 10.1016/j.celrep.2018.06.055

PMCID:: PMC6434950

Abstract Article PDF–2.7M

Select item 496881719.

Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis

Ya-Li Zheng, Xia Zhang, Hai-Xia Fu, Mei Guo, Varsha Shukla, Niranjana D. Amin, Jing E, Li Bao, Hong-Yan Luo, Bo Li, Xiao-Hua Lu, Yong-Cai Gao

PLoS One. 2016; 11(8): e0160252. Published online 2016 Aug 1. doi: 10.1371/journal.pone.0160252

PMCID:: PMC4968817

Abstract Article PDF–1.0M

Select item 493695220.

Involvement of aberrant Cdk5/p25 activity in experimental traumatic brain injury

Mohammad A. Yousuf, Chunfeng Tan, Melissa I. Torres-Altoro, Fang-Min Lu, Erik Plautz, Shanrong Zhang, Masaya Takahashi, Adan Hernandez, Steven G. Kernie, Florian Plattner, James A. Bibb

J Neurochem. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: J Neurochem. 2016 Jul; 138(2): 317–327. Published online 2016 May 25. doi: 10.1111/jnc.13620