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Select item 90350711.

Cyclin‐dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle

Sun Hye Kim, Liliana R. L. Rodriguez, Everardo Macias, Marcelo L. Rodriguez‐Puebla

Cell Biol Int. 2022 May; 46(5): 737–746. Published online 2022 Feb 3. doi: 10.1002/cbin.11765

PMCID:: PMC9035071

Abstract Article PDF–2.2M

Select item 82627912.

Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Iliana K. Kerzeli, Martin Lord, Milena Doroszko, Ramy Elgendy, Aikaterini Chourlia, Ivan Stepanek, Elinor Larsson, Luuk van Hooren, Sven Nelander, Per-Uno Malmstrom, Anca Dragomir, Ulrika Segersten, Sara M. Mangsbo

PLoS One. 2021; 16(7): e0253178. Published online 2021 Jul 7. doi: 10.1371/journal.pone.0253178

Correction in:: PLoS One. 2024; 19(5): e0304890.

PMCID:: PMC8262791

Abstract Article PDF–5.1M

Select item 75075723.

Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues

Judit Castillo‐Armengol, Valentin Barquissau, Sarah Geller, Honglei Ji, Ilenia Severi, Wiebe Venema, Eric Aria Fenandez, Catherine Moret, Katharina Huber, Lucia C Leal‐Esteban, Anita Nasrallah, Laia Martinez‐Carreres, Guy Niederhäuser, Patricia Seoane‐Collazo, Sylviane Lagarrigue, Miguel López, Antonio Giordano, Sophie Croizier, Bernard Thorens, Isabel C Lopez‐Mejia, Lluis Fajas

EMBO Rep. 2020 Sep 3; 21(9): e49807. Published online 2020 Jul 12. doi: 10.15252/embr.201949807

PMCID:: PMC7507572

Abstract Article PDF–6.5M

Select item 36367454.

CDK4: A Key Player in the Cell Cycle, Development, and Cancer

Stacey J. Baker, E. Premkumar Reddy

Genes Cancer. 2012 Nov; 3(11-12): 658–669. doi: 10.1177/1947601913478972

PMCID:: PMC3636745

Abstract Article PDF–299K

Select item 32968845.

THE SOLE PRESENCE OF CDK4 IS NOT A SOLID CRITERION FOR DISCRIMINATING BETWEEN TUMOR AND HEALTHY PANCREATIC TISSUES

Jordi Altirriba, Ainhoa García, Begoña Sánchez, Laura Haba, Sean Altekruse, Thomas Stratmann, Josep Antoni Bombí, Cristóbal Mezquita, Ramon Gomis, Conchi Mora

Int J Cancer. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Int J Cancer. 2012 Jun 1; 130(11): 2743–2745. Published online 2011 Aug 29. doi: 10.1002/ijc.26313

PMCID:: PMC3296884

Article PDF–835K

Select item 30478156.

Role of Cdk4 in lymphocyte function and allergen response

Yu-Hua Chow, Xiao Dong Zhu, Li Liu, Barbara R Schwartz, Xiao Zhu Huang, John M Harlan, Lynn M Schnapp

Cell Cycle. 2010 Dec 15; 9(24): 4922–4930. Published online 2010 Dec 15. doi: 10.4161/cc.9.24.14209

PMCID:: PMC3047815

Abstract Article PDF–609K

Select item 28016127.

Cdk4 Regulates Recruitment of Quiescent β-Cells and Ductal Epithelial Progenitors to Reconstitute β-Cell Mass

Ji-Hyeon Lee, Junghyo Jo, Anandwardhan A. Hardikar, Vipul Periwal, Sushil G. Rane

PLoS One. 2010; 5(1): e8653. Published online 2010 Jan 13. doi: 10.1371/journal.pone.0008653

PMCID:: PMC2801612

Abstract Article PDF–618K

Select item 26540298.

A GRFa2/Prop1/Stem (GPS) Cell Niche in the Pituitary

Montse Garcia-Lavandeira, Víctor Quereda, Ignacio Flores, Carmen Saez, Esther Diaz-Rodriguez, Miguel A. Japon, Aymee K. Ryan, Maria A. Blasco, Carlos Dieguez, Marcos Malumbres, Clara V. Alvarez

PLoS One. 2009; 4(3): e4815. Published online 2009 Mar 13. doi: 10.1371/journal.pone.0004815

PMCID:: PMC2654029

Abstract Article PDF–2.0M

Select item 18507399.

cdk4 Deficiency Inhibits Skin Tumor Development but Does Not Affect Normal Keratinocyte Proliferation

Marcelo L. Rodriguez-Puebla, Paula L. Miliani de Marval, Margaret LaCava, David S. Moons, Hiroaki Kiyokawa, Claudio J. Conti

Am J Pathol. 2002 Aug; 161(2): 405–411. doi: 10.1016/S0002-9440(10)64196-X

PMCID:: PMC1850739

Abstract Article PDF–275K

Select item 18748610.

Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence

Xianghong Zou, Dipankar Ray, Aileen Aziyu, Konstantin Christov, Alexander D. Boiko, Andrei V. Gudkov, Hiroaki Kiyokawa

Genes Dev. 2002 Nov 15; 16(22): 2923–2934. doi: 10.1101/gad.1033002

PMCID:: PMC187486

Abstract Article PDF–370K

Select item 13974111.

Germ Line Transmission of the Cdk4^R24C Mutation Facilitates Tumorigenesis and Escape from Cellular Senescence

Sushil G. Rane, Stephen C. Cosenza, Richard V. Mettus, E. Premkumar Reddy

Mol Cell Biol. 2002 Jan; 22(2): 644–656. doi: 10.1128/MCB.22.2.644-656.2002

PMCID:: PMC139741

Abstract Article PDF–798K

Select item 8469612.

Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27^Kip1 Activity

Tateki Tsutsui, Bahar Hesabi, David S. Moons, Pier Paolo Pandolfi, Kimberly S. Hansel, Andrew Koff, Hiroaki Kiyokawa

Mol Cell Biol. 1999 Oct; 19(10): 7011–7019. doi: 10.1128/mcb.19.10.7011

PMCID:: PMC84696

Abstract Article PDF–2.0M

Select item 1578313.

Identification of CDK4 as a target of c-MYC

Heiko Hermeking, Carlo Rago, Marino Schuhmacher, Qing Li, John F. Barrett, Alvaro J. Obaya, Brenda C. O'Connell, Maria K. Mateyak, Wanny Tam, Franz Kohlhuber, Chi V. Dang, John M. Sedivy, Dirk Eick, Bert Vogelstein, Kenneth W. Kinzler

Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5): 2229–2234. Published online 2000 Feb 25. doi: 10.1073/pnas.050586197

PMCID:: PMC15783

Abstract Article PDF–314K

Select item 1087257714.

CDK4/6 inhibition sensitizes intracranial tumors to PD-1 blockade in preclinical models of brain metastasis

Naema Nayyar, Magali A de Sauvage, Jane Chuprin, Emily M Sullivan, Mohini Singh, Consuelo Torrini, Britney S Zhang, Sushobhana Bandyopadhyay, Keith A Daniels, Christopher Alvarez-Breckenridge, Ashish Dahal, Michael A Brehm, Priscilla K Brastianos

Clin Cancer Res. Author manuscript; available in PMC 2024 Jul 17.

Published in final edited form as: Clin Cancer Res. 2024 Jan 17; 30(2): 420–435. doi: 10.1158/1078-0432.CCR-23-0433

PMCID:: PMC10872577

Abstract Article PDF–2.5M

Select item 1069950815.

Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation

Hannah Knight, Giancarlo Abis, Manpreet Kaur, Hannah L.H. Green, Susanne Krasemann, Kristin Hartmann, Steven Lynham, James Clark, Lan Zhao, Clemens Ruppert, Astrid Weiss, Ralph T. Schermuly, Philip Eaton, Olena Rudyk

Circ Res. 2023 Dec 8; 133(12): 966–988. Published online 2023 Nov 13. doi: 10.1161/CIRCRESAHA.122.321836

PMCID:: PMC10699508

Abstract Article PDF–11M

Select item 885581016.

RB expression confers sensitivity to CDK4/6 inhibitor–mediated radiosensitization across breast cancer subtypes

Andrea M. Pesch, Nicole H. Hirsh, Anna R. Michmerhuizen, Kassidy M. Jungles, Kari Wilder-Romans, Benjamin C. Chandler, Meilan Liu, Lynn M. Lerner, Charles A. Nino, Connor Ward, Erin F. Cobain, Theodore S. Lawrence, Lori J. Pierce, James M. Rae, Corey W. Speers

JCI Insight. 2022 Feb 8; 7(3): e154402. Published online 2022 Feb 8. doi: 10.1172/jci.insight.154402