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Items: 1 to 20 of 299

1.
CircCDC42-encoded CDC42-165aa regulates macrophage pyroptosis in Klebsiella pneumoniae infection through Pyrin inflammasome activation
Nana Xu, Jiebang Jiang, Fei Jiang, Guokai Dong, Li Meng, Meng Wang, Jing Chen, Cong Li, Yongping Shi, Sisi He, Rongpeng Li
Nat Commun. 2024; 15: 5730. Published online 2024 Jul 8. doi: 10.1038/s41467-024-50154-x
PMCID:
PMC11231140
AbstractArticlePDF–3.0M
2.
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice
Jing He, Meng-Yu Tang, Li-Xin Liu, Chen-Xian Kong, Wen Chen, Lu Wang, Shao-Bin Zhi, Hong-Wei Sun, Yu-Chun Huang, Guo-Yu Chen, Hong-Bo Xin, Ke-Yu Deng
Cell Mol Gastroenterol Hepatol. 2024; 17(6): 965–981. Published online 2024 Feb 9. doi: 10.1016/j.jcmgh.2024.01.023
PMCID:
PMC11047801
AbstractArticlePDF–7.7M
3.
Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion
Shan Jiang, Chun-mei Xu, Shuai Yao, Rui Zhang, Xian-zhi Li, Ru-zhen Zhang, Tian-yue Xie, Yi-qian Xing, Qian Zhang, Xiao-jun Zhou, Lin Liao, Jian-jun Dong
Front Endocrinol (Lausanne) 2022; 13: 905703. Published online 2022 Aug 10. doi: 10.3389/fendo.2022.905703
PMCID:
PMC9399854
AbstractArticlePDF–4.2M
4.
Palmitoylation of the small GTPase Cdc42 by DHHC5 modulates spine formation and gene transcription
Alexander Wirth, Josephine Labus, Dalia Abdel Galil, Yvonne Schill, Silke Schmidt, Tania Bunke, Nataliya Gorinski, Norihiko Yokoi, Masaki Fukata, Evgeni Ponimaskin
J Biol Chem. 2022 Jun; 298(6): 102048. Published online 2022 May 18. doi: 10.1016/j.jbc.2022.102048
PMCID:
PMC9190017
AbstractArticlePDF–1.6M
5.
Suppression of elevated Cdc42 activity promotes the regenerative potential of aged intestinal stem cells
Kodandaramireddy Nalapareddy, Aishlin Hassan, Leesa L. Sampson, Yi Zheng, Hartmut Geiger
iScience. 2021 Apr 23; 24(4): 102362. Published online 2021 Mar 26. doi: 10.1016/j.isci.2021.102362
PMCID:
PMC8044426
AbstractArticlePDF–4.6M
6.
Photoactivatable CaMKII induces synaptic plasticity in single synapses
Akihiro C. E. Shibata, Hiromi H. Ueda, Kei Eto, Maki Onda, Aiko Sato, Tatsuko Ohba, Junichi Nabekura, Hideji Murakoshi
Nat Commun. 2021; 12: 751. Published online 2021 Feb 2. doi: 10.1038/s41467-021-21025-6
PMCID:
PMC7854602
AbstractArticlePDF–2.7M
7.
Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regeneration
Xiao Zhang, Sheila Bandyopadhyay, Leandro Pires Araujo, Kevin Tong, Juan Flores, Daniel Laubitz, Yanlin Zhao, George Yap, Jingren Wang, Qingze Zou, Ronaldo Ferraris, Lanjing Zhang, Wenwei Hu, Edward M. Bonder, Pawel R. Kiela, Robert Coffey, Michael P. Verzi, Ivaylo I. Ivanov, Nan Gao
JCI Insight. 2020 Aug 20; 5(16): e135923. Published online 2020 Aug 20. doi: 10.1172/jci.insight.135923
PMCID:
PMC7455142
AbstractArticlePDF–17M
8.
Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis
Mark S. Ladinsky, Leandro P. Araujo, Xiao Zhang, John Veltri, Marta Galan-Diez, Salima Soualhi, Carolyn Lee, Koichiro Irie, Elisha Y. Pinker, Seiko Narushima, Sheila Bandyopadhyay, Manabu Nagayama, Wael Elhenawy, Brian K. Coombes, Ronaldo P. Ferraris, Kenya Honda, Iliyan D. Iliev, Nan Gao, Pamela J. Bjorkman, Ivaylo I. Ivanov
Science. Author manuscript; available in PMC 2020 Mar 8.
Published in final edited form as: Science. 2019 Mar 8; 363(6431): eaat4042. doi: 10.1126/science.aat4042
PMCID:
PMC6708280
AbstractArticlePDF–4.5M
9.
Cdc42 negatively regulates endocytosis during apical membrane maintenance in live animals
Akiko Shitara, Lenka Malec, Seham Ebrahim, Desu Chen, Christopher Bleck, Matthew P. Hoffman, Roberto Weigert
Mol Biol Cell. 2019 Feb 1; 30(3): 324–332. doi: 10.1091/mbc.E18-10-0615
PMCID:
PMC6589572
AbstractArticlePDF–1.6M
10.
Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization
Wei Liu, Wei Du, Xun Shang, Lei Wang, Chris Evelyn, Maria Carolina Florian, Marnie A. Ryan, Ahmad Rayes, Xueheng Zhao, Kenneth Setchell, Jarek Meller, Fukun Guo, Nicolas Nassar, Hartmut Geiger, Qishen Pang, Yi Zheng
Leukemia. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Leukemia. 2019 Mar; 33(3): 749–761. Published online 2018 Sep 25. doi: 10.1038/s41375-018-0251-5
PMCID:
PMC6414073
AbstractArticlePDF–965K
11.
Alternative 3′ UTRs direct localization of functionally diverse protein isoforms in neuronal compartments
Camilla Ciolli Mattioli, Aviv Rom, Vedran Franke, Koshi Imami, Gerard Arrey, Mandy Terne, Andrew Woehler, Altuna Akalin, Igor Ulitsky, Marina Chekulaeva
Nucleic Acids Res. 2019 Mar 18; 47(5): 2560–2573. Published online 2018 Dec 22. doi: 10.1093/nar/gky1270
PMCID:
PMC6411841
AbstractArticlePDF–2.6M
12.
Rational targeting Cdc42 restrains Th2 cell differentiation and prevents allergic airway inflammation
Jun-Qi Yang, Khalid W. Kalim, Yuan Li, Xin Duan, Phuong Nguyen, Gurjit K. Khurana Hershey, John Kroner, Brandy Ruff, Li Zhang, Nathan Salomonis, Mark Rochman, Ting Wen, Yi Zheng, Fukun Guo
Clin Exp Allergy. Author manuscript; available in PMC 2020 Jan 1.
Published in final edited form as: Clin Exp Allergy. 2019 Jan; 49(1): 92–107. Published online 2018 Nov 13. doi: 10.1111/cea.13293
PMCID:
PMC6310654
AbstractArticlePDF–2.9M
13.
Cdc42-dependent modulation of rigidity sensing and cell spreading in tumor repopulating cells
Farhan Chowdhury, Sultan Doğanay, Benjamin J. Leslie, Rishi Singh, Kshitij Amar, Bhavana Talluri, Seongjin Park, Ning Wang, Taekjip Ha
Biochem Biophys Res Commun. Author manuscript; available in PMC 2018 Dec 7.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Jun 7; 500(3): 557–563. Published online 2018 Apr 23. doi: 10.1016/j.bbrc.2018.04.085
PMCID:
PMC6133653
AbstractArticlePDF–1.5M
14.
CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes
Hao Yan, Jiawei Zhang, Jia Wen, Yibo Wang, Wanbao Niu, Zhen Teng, Tongtong Zhao, Yanli Dai, Yan Zhang, Chao Wang, Yingying Qin, Guoliang Xia, Hua Zhang
BMC Biol. 2018; 16: 73. Published online 2018 Jul 5. doi: 10.1186/s12915-018-0541-4
PMCID:
PMC6033292
AbstractArticlePDF–16M
15.
Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury
Jiawen Lv, Junchao Zeng, Fukun Guo, Yiran Li, Mengying Xu, Yuanxiong Cheng, Lin Zhang, Shaoxi Cai, Yinghua Chen, Yi Zheng, Guodong Hu
Respir Res. 2018; 19: 27. Published online 2018 Feb 8. doi: 10.1186/s12931-018-0729-8
PMCID:
PMC5806471
AbstractArticlePDF–4.3M
16.
Non-canonical Wnt signaling regulates neural stem cell quiescence during homeostasis and after demyelination
Manideep Chavali, Michael Klingener, Alexandros G. Kokkosis, Yury Garkun, Sylwia Felong, Arianna Maffei, Adan Aguirre
Nat Commun. 2018; 9: 36. Published online 2018 Jan 2. doi: 10.1038/s41467-017-02440-0
PMCID:
PMC5750230
AbstractArticlePDF–4.6M
17.
An Essential Role for Cdc42 in the Functioning of the Adult Mammary Gland
Joseph E. Druso, Makoto Endo, Miao-chong Joy Lin, Xu Peng, Marc A. Antonyak, Stephanie Meller, Richard A. Cerione
J Biol Chem. 2016 Apr 22; 291(17): 8886–8895. Published online 2016 Feb 24. doi: 10.1074/jbc.M115.694349
PMCID:
PMC4861458
AbstractArticlePDF–2.4M
18.
Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells
Anna M. Schulz, Susanne Stutte, Sebastian Hogl, Nancy Luckashenak, Diana Dudziak, Céline Leroy, Ignasi Forné, Axel Imhof, Stephan A. Müller, Cord H. Brakebusch, Stefan F. Lichtenthaler, Thomas Brocker
J Cell Biol. 2015 Nov 9; 211(3): 553–567. doi: 10.1083/jcb.201503128
PMCID:
PMC4639873
AbstractArticlePDF–6.3M
19.
Pharmacological inhibition of EGFR signaling enhances G-CSF–induced hematopoietic stem cell mobilization
Marnie A Ryan, Kalpana J Nattamai, Ellen Xing, David Schleimer, Deidre Daria, Amitava Sengupta, Anja Köhler, Wei Liu, Matthias Gunzer, Michael Jansen, Nancy Ratner, Timothy D Le Cras, Amanda Waterstrat, Gary Van Zant, Jose A Cancelas, Yi Zheng, Hartmut Geiger
Nat Med. Author manuscript; available in PMC 2015 Jun 13.
Published in final edited form as: Nat Med. 2010 Oct; 16(10): 1141–1146. Published online 2010 Sep 26. doi: 10.1038/nm.2217
PMCID:
PMC4464748
ArticlePDF–1.3M
20.
The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells
Natalija Gerasimcik, Carin I. M. Dahlberg, Marisa A. P. Baptista, Michel J. Massaad, Raif S. Geha, Lisa S. Westerberg, Eva Severinson
J Immunol. 2015 May 15; 194(10): 4750–4758. Published online 2015 Apr 13. doi: 10.4049/jimmunol.1401634
PMCID:
PMC4416737
AbstractArticlePDF–1.8M

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