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Select item 39640491.

Duality of the murine CD8 compartment

Raphaël Genolet, Julie Leignadier, Magne Østerås, Laurent Farinelli, Brian J. Stevenson, Immanuel F. Luescher

Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11): E1007–E1015. Published online 2014 Mar 4. doi: 10.1073/pnas.1317847111

PMCID:: PMC3964049

Abstract Article PDF–2.3M

Select item 3050542.

Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

H Nakauchi, Y Shinkai, K Okumura

Proc Natl Acad Sci U S A. 1987 Jun; 84(12): 4210–4214. doi: 10.1073/pnas.84.12.4210

PMCID:: PMC305054

Summary Page Browse PDF–1024K

Select item 2991873.

Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

M Panaccio, M T Gillespie, I D Walker, L Kirszbaum, J A Sharpe, G H Tobias, I F McKenzie, N J Deacon

Proc Natl Acad Sci U S A. 1987 Oct; 84(19): 6874–6878. doi: 10.1073/pnas.84.19.6874

PMCID:: PMC299187

Summary Page Browse PDF–1.1M

Select item 69854544.

Constitutive CD8 expression drives innate CD8⁺ T-cell differentiation via induction of iNKT2 cells

Satoshi Kojo, Michiko Ohno-Oishi, Hisashi Wada, Sebastian Nieke, Wooseok Seo, Sawako Muroi, Ichiro Taniuchi

Life Sci Alliance. 2020 Feb; 3(2): e202000642. Published online 2020 Jan 24. doi: 10.26508/lsa.202000642

PMCID:: PMC6985454

Abstract Article PDF–2.4M

Select item 40977995.

Role of CD8⁺ T Cells and Lymphoid Dendritic Cells in Protection from Ocular Herpes Simplex Virus 1 Challenge in Immunized Mice

Harry Matundan, Kevin R. Mott, Homayon Ghiasi

J Virol. 2014 Jul; 88(14): 8016–8027. doi: 10.1128/JVI.00913-14

PMCID:: PMC4097799

Abstract Article PDF–1.1M

Select item 36471856.

Interleukin-4-induced loss of CD8 expression and cytolytic function in effector CD8 T cells persists long term in vivo

Stuart Olver, Simon H Apte, Adriana Baz, Anne Kelso, Norbert Kienzle

Immunology. 2013 Jun; 139(2): 187–196. Published online 2013 Apr 23. doi: 10.1111/imm.12068

PMCID:: PMC3647185

Abstract Article PDF–462K

Select item 27827057.

Structural basis of the CD8αβ/MHCI interaction: focused recognition orients CD8β to a T cell proximal position

Rui Wang, Kannan Natarajan, David H. Margulies

J Immunol. Author manuscript; available in PMC 2010 Aug 15.

Published in final edited form as: J Immunol. 2009 Aug 15; 183(4): 2554–2564. Published online 2009 Jul 22. doi: 10.4049/jimmunol.0901276

PMCID:: PMC2782705

Abstract Article PDF–3.4M

Select item 26312328.

The crystal structure of CD8αβ in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8αβ to MHC class I

D. A. Shore, H. Issafras, E. Landais, L. Teyton, I. A. Wilson

J Mol Biol. Author manuscript; available in PMC 2009 Dec 31.

Published in final edited form as: J Mol Biol. 2008 Dec 31; 384(5): 1190–1202. Published online 2008 Oct 7. doi: 10.1016/j.jmb.2008.09.069

PMCID:: PMC2631232

Abstract Article PDF–4.6M

Select item 21939579.

Unraveling a Revealing Paradox: Why Major Histocompatibility Complex I–signaled Thymocytes “Paradoxically” Appear as CD4⁺8^lo Transitional Cells During Positive Selection of CD8⁺ T Cells

Remy Bosselut, Terry I. Guinter, Susan O. Sharrow, Alfred Singer

J Exp Med. 2003 Jun 16; 197(12): 1709–1719. doi: 10.1084/jem.20030170

PMCID:: PMC2193957

Abstract Article PDF–260K

Select item 219163510.

Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice

J Exp Med. 1994 Sep 1; 180(3): 959–967. doi: 10.1084/jem.180.3.959

PMCID:: PMC2191635

Summary PDF–898K

Select item 851784911.

Ribosylation of the CD8αβ heterodimer permits binding of the nonclassical major histocompatibility molecule, H2-Q10

Katharine Jennifer Goodall, Angela Nguyen, Daniel Mark Andrews, Lucy Catherine Sullivan

J Biol Chem. 2021 Oct; 297(4): 101141. Published online 2021 Aug 31. doi: 10.1016/j.jbc.2021.101141

PMCID:: PMC8517849

Abstract Article PDF–1.7M

Select item 397367912.

CD8α Dendritic Cells Drive Establishment of HSV-1 Latency

Kevin R. Mott, Sariah J. Allen, Mandana Zandian, Bindu Konda, Behrooz G. Sharifi, Clinton Jones, Steven L. Wechsler, Terrence Town, Homayon Ghiasi

PLoS One. 2014; 9(4): e93444. Published online 2014 Apr 2. doi: 10.1371/journal.pone.0093444

PMCID:: PMC3973679

Abstract Article PDF–2.1M

Select item 324569613.

CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I

Vasily Rybakin, Jean-Pierre Clamme, Jeanette Ampudia, Pia P Yachi, Nicholas R J Gascoigne

EMBO Rep. 2011 Dec; 12(12): 1251–1256. Published online 2011 Nov 11. doi: 10.1038/embor.2011.209

PMCID:: PMC3245696

Abstract Article PDF–601K

Select item 276473814.

The TCR's α-CPM promotes close approximation of the CD8 co-receptor allowing efficient signal initiation

Michel Mallaun, Dieter Naeher, Mark A. Daniels, Pia P. Yachi, Barbara Hausmann, Immanuel F. Luescher, Nicholas R.J. Gascoigne, Ed Palmer

J Immunol. Author manuscript; available in PMC 2009 Oct 20.

Published in final edited form as: J Immunol. 2008 Jun 15; 180(12): 8211–8221. doi: 10.4049/jimmunol.180.12.8211

PMCID:: PMC2764738

Abstract Article PDF–1009K

Select item 213973315.

GENETIC CORRELATION OF A MOUSE LIGHT CHAIN VARIABLE REGION MARKER WITH A THYMOCYTE SURFACE ANTIGEN

Paul D. Gottlieb

J Exp Med. 1974 Oct 31; 140(5): 1432–1437. doi: 10.1084/jem.140.5.1432

PMCID:: PMC2139733

Summary PDF–331K

Select item 424823916.

Ligand engaged TCR is triggered by Lck not associated with CD8 coreceptor

Javier Casas, Joanna Brzostek, Veronika I. Zarnitsyna, Jin-sung Hong, Qianru Wei, John A.H. Hoerter, Guo Fu, Jeanette Ampudia, Rose Zamoyska, Cheng Zhu, Nicholas R.J. Gascoigne

Nat Commun. Author manuscript; available in PMC 2015 May 27.

Published in final edited form as: Nat Commun. 2014; 5: 5624. Published online 2014 Nov 27. doi: 10.1038/ncomms6624

PMCID:: PMC4248239

Abstract Article PDF–2.1M

Select item 375574017.

Interplay between TCR Affinity and Necessity of Coreceptor Ligation: High-Affinity Peptide-MHC/TCR Interaction Overcomes Lack of CD8 Engagement

Samantha E. Kerry, Jennifer Buslepp, Lorraine A. Cramer, Robert Maile, Lucinda L. Hensley, Alma I. Nielsen, Paula Kavathas, Barbara J. Vilen, Edward J. Collins, Jeffrey A. Frelinger

J Immunol. Author manuscript; available in PMC 2013 Aug 28.

Published in final edited form as: J Immunol. 2003 Nov 1; 171(9): 4493–4503. doi: 10.4049/jimmunol.171.9.4493