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Select item 107565321.

Pathogen-driven nucleotide overload triggers mitochondria-centered cell death in phagocytes

Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

PLoS Pathog. 2023 Dec; 19(12): e1011892. Published online 2023 Dec 29. doi: 10.1371/journal.ppat.1011892

PMCID:: PMC10756532

Abstract Article PDF–2.7M

Select item 98737352.

Caspase-9 driven murine model of selective cell apoptosis and efferocytosis

Lena Batoon, Amy J. Koh, Rahasudha Kannan, Laurie K. McCauley, Hernan Roca

Cell Death Dis. 2023 Jan; 14(1): 58. Published online 2023 Jan 24. doi: 10.1038/s41419-023-05594-6

PMCID:: PMC9873735

Abstract Article PDF–11M

Select item 96433613.

Neurovascular injury associated non-apoptotic endothelial caspase-9 and astroglial caspase-9 mediate inflammation and contrast sensitivity decline

Crystal Colón Ortiz, Albertine M. Neal, Maria I. Avrutsky, Monica Choi, Jade Smart, Jacqueline Lawson, Carol M. Troy

Cell Death Dis. 2022 Nov; 13(11): 937. Published online 2022 Nov 8. doi: 10.1038/s41419-022-05387-3

Correction in:: Cell Death Dis. 2022 Nov; 13(11): 993.

PMCID:: PMC9643361

Abstract Article PDF–5.7M

Select item 85706084.

Genome-wide association studies identify the role of caspase-9 in kidney disease

Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Xin Sheng, Matthew Seasock, Hongbo Liu, Ziyuan Ma, Matthew Palmer, Katalin Susztak

Sci Adv. 2021 Nov; 7(45): eabi8051. Published online 2021 Nov 5. doi: 10.1126/sciadv.abi8051

PMCID:: PMC8570608

Abstract Article PDF–12M

Select item 53631965.

Inducible Caspase-9 Selectively Modulates the Toxicities of CD19-Specific Chimeric Antigen Receptor-Modified T Cells

Iulia Diaconu, Brandon Ballard, Ming Zhang, Yuhui Chen, John West, Gianpietro Dotti, Barbara Savoldo

Mol Ther. 2017 Mar 1; 25(3): 580–592. Published online 2017 Feb 8. doi: 10.1016/j.ymthe.2017.01.011

PMCID:: PMC5363196

Abstract Article PDF–2.1M

Select item 50075296.

Inhibition of caspase-9 aggravates acute liver injury through suppression of cytoprotective autophagy

Rui Guo, Bin Lin, Jing Fei Pan, Emily C. Liong, Ai Min Xu, Moussa Youdim, Man Lung Fung, Kwok Fai So, George L. Tipoe

Sci Rep. 2016; 6: 32447. Published online 2016 Sep 1. doi: 10.1038/srep32447

PMCID:: PMC5007529

Abstract Article PDF–1.7M

Select item 30055637.

Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases

Mark F. van Delft, Darrin P. Smith, Mireille H. Lahoud, David C.S. Huang, Jerry M. Adams

Cell Death Differ. Author manuscript; available in PMC 2010 Dec 21.

Published in final edited form as: Cell Death Differ. 2010 May; 17(5): 821–832. Published online 2009 Nov 13. doi: 10.1038/cdd.2009.166

PMCID:: PMC3005563

Abstract Article PDF–2.2M

Select item 19328438.

Involvement of Caspase-9 in the Inhibition of Necrosis of RAW 264 Cells Infected with Mycobacterium tuberculosis

Ryosuke Uchiyama, Ikuo Kawamura, Takao Fujimura, Michiko Kawanishi, Kohsuke Tsuchiya, Takanari Tominaga, Taijin Kaku, Yutaka Fukasawa, Shunsuke Sakai, Takamasa Nomura, Masao Mitsuyama

Infect Immun. 2007 Jun; 75(6): 2894–2902. Published online 2007 Apr 2. doi: 10.1128/IAI.01639-06

PMCID:: PMC1932843

Abstract Article PDF–711K

Select item 16367479.

Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9

Mads Gyrd-Hansen, Thomas Farkas, Nicole Fehrenbacher, Lone Bastholm, Maria Høyer-Hansen, Folmer Elling, David Wallach, Richard Flavell, Guido Kroemer, Jesper Nylandsted, Marja Jäättelä

Mol Cell Biol. 2006 Nov; 26(21): 7880–7891. Published online 2006 Sep 11. doi: 10.1128/MCB.00716-06

Correction in:: Mol Cell Biol. 2018 Jan 15; 38(2): e00563-17.

PMCID:: PMC1636747

Abstract Article PDF–1.0M

Select item 29182910.

The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model

Haruhisa Inoue, Kayoko Tsukita, Takuji Iwasato, Yasuyuki Suzuki, Masanori Tomioka, Minako Tateno, Masahiro Nagao, Akihiro Kawata, Takaomi C. Saido, Masayuki Miura, Hidemi Misawa, Shigeyoshi Itohara, Ryosuke Takahashi

EMBO J. 2003 Dec 15; 22(24): 6665–6674. doi: 10.1093/emboj/cdg634

PMCID:: PMC291829

Abstract Article PDF–373K

Select item 1071185811.

Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity

Jingyang Li, Xiaoyu Han, Mayu Sun, Weida Li, Guanghuan Yang, Huiyi Chen, Bao Guo, Jingquan Li, Xiaoguang Li, Hui Wang

J Immunother Cancer. 2023; 11(12): e007625. Published online 2023 Dec 6. doi: 10.1136/jitc-2023-007625

PMCID:: PMC10711858

Abstract Article PDF–8.4M

Select item 731155112.

Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion

Maria I. Avrutsky, Crystal Colón Ortiz, Kendra V. Johnson, Anna M. Potenski, Claire W. Chen, Jacqueline M. Lawson, Alexandra J. White, Stephanie K. Yuen, Fatima N. Morales, Elisa Canepa, Scott Snipas, Guy S. Salvesen, Ying Y. Jean, Carol M. Troy

Nat Commun. 2020; 11: 3173. Published online 2020 Jun 23. doi: 10.1038/s41467-020-16902-5

Correction in:: Nat Commun. 2020; 11: 3502.

PMCID:: PMC7311551

Abstract Article PDF–17M

Select item 676235713.

Programmed Cell Death of Developing Mammalian Neurons after Genetic Deletion of Caspases

Ronald W. Oppenheim, Richard A. Flavell, Sharon Vinsant, David Prevette, Chia-Y. Kuan, Pasko Rakic

J Neurosci. 2001 Jul 1; 21(13): 4752–4760. doi: 10.1523/JNEUROSCI.21-13-04752.2001

PMCID:: PMC6762357

Abstract Article PDF–1.7M

Select item 587064414.

BICAO-induced ischaemia caused depressive-like behaviours and caspase-8/-9-dependent brain regional neural cell apoptosis in mice

Shuiqiao Liu, Song Han, Qingqing Dai, Shujuan Li, Junfa Li

Stroke Vasc Neurol. 2018 Mar; 3(1): 1–8. Published online 2017 Dec 17. doi: 10.1136/svn-2017-000109

PMCID:: PMC5870644

Abstract Article PDF–2.3M

Select item 477728115.

Activation of Bcl-2-Caspase-9 Apoptosis Pathway in the Testis of Asthmatic Mice

Wenyuan Xu, Guifang Guo, Junjuan Li, Zhaolei Ding, Jianhui Sheng, Juan Li, Wei Tan

PLoS One. 2016; 11(3): e0149353. Published online 2016 Mar 3. doi: 10.1371/journal.pone.0149353

PMCID:: PMC4777281

Abstract Article PDF–1.6M

Select item 435737716.

Sublethal Caspase Activation Promotes Generation of Cardiomyocytes from Embryonic Stem Cells

Ivana Bulatovic, Cristian Ibarra, Cecilia Österholm, Heng Wang, Antonio Beltrán-Rodríguez, Manuel Varas-Godoy, Agneta Månsson-Broberg, Per Uhlén, András Simon, Karl-Henrik Grinnemo

PLoS One. 2015; 10(3): e0120176. Published online 2015 Mar 12. doi: 10.1371/journal.pone.0120176

PMCID:: PMC4357377

Abstract Article PDF–2.4M

Select item 427117917.

Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice

Elise Peterson Lu, Michael McLellan, Li Ding, Robert Fulton, Elaine R. Mardis, Richard K. Wilson, Christopher A. Miller, Peter Westervelt, John F. DiPersio, Daniel C. Link, Matthew J. Walter, Timothy J. Ley, Timothy A. Graubert

Blood. 2014 Dec 18; 124(26): 3887–3895. Prepublished online 2014 Oct 27. doi: 10.1182/blood-2014-06-582551

PMCID:: PMC4271179

Abstract Article

Select item 361449118.

Aneuploid Cells Are Differentially Susceptible to Caspase-Mediated Death during Embryonic Cerebral Cortical Development

Suzanne E. Peterson, Amy H. Yang, Diane M. Bushman, Jurjen W. Westra, Yun C. Yung, Serena Barral, Tetsuji Mutoh, Stevens K. Rehen, Jerold Chun

J Neurosci. 2012 Nov 14; 32(46): 16213–16222. doi: 10.1523/JNEUROSCI.3706-12.2012

PMCID:: PMC3614491

Abstract Article PDF–1.5M

Select item 275579119.

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon

Angelo A. Izzo, Gabriella Aviello, Stefania Petrosino, Pierangelo Orlando, Giovanni Marsicano, Beat Lutz, Francesca Borrelli, Raffaele Capasso, Santosh Nigam, Francesco Capasso, Vincenzo Di Marzo, Endocannabinoid Research Group

J Mol Med. 2008 Jan; 86(1): 89–98. Published online 2007 Sep 6. doi: 10.1007/s00109-007-0248-4