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Select item 68339421.

LUNG CANCER RISK IN NEVER SMOKERS OF EUROPEAN DESCENT IS ASSOCIATED WITH GENETIC VARIATION IN THE 5_P15.33 TERT-CLPTM1L REGION

Rayjean J. Hung, Margaret R. Spitz, Richard S. Houlston, Ann G. Schwartz, John K. Field, Jun Ying, Yafang Li, Younghun Han, Xuemei Ji, Wei Chen, Xifeng Wu, Ivan P. Gorlov, Jie Na, Mariza de Andrade, Geoffrey Liu, Yonathan Brhane, Nancy Diao, Angela Wenzlaff, Michael P.A. Davies, Triantafillos Liloglou, Maria Timofeeva, Thomas Muley, Hedy Rennert, Walid Saliba, Bríd M. Ryan, Elise Bowman, Juan-Miguel Barros-Dios, Mónica Pérez-Ríos, Hal Morgenstern, Shanbeh Zienolddiny, Vidar Skaug, Donatella Ugolini, Stefano Bonassi, Erik H.F.M. van der Heijden, Adonina Tardon, Stig E. Bojesen, Maria Teresa Landi, Mattias Johansson, Heike Bickeböller, Susanne Arnold, Loic Le Marchand, Olle Melander, Angeline Andrew, Kjell Grankvist, Neil Caporaso, M. Dawn Teare, Matthew B. Schabath, Melinda C. Aldrich, Lambertus A. Kiemeney, H-Erich Wichmann, Philip Lazarus, Jose Mayordomo, Monica Neri, Aage Haugen, Zuo-Feng Zhang, Alberto Ruano-Raviña, Hermann Brenner, Curtis C. Harris, Irene Orlow, Gadi Rennert, Angela Risch, Paul Brennan, David C. Christiani, Christopher I. Amos, Ping Yang, Olga Y. Gorlova

J Thorac Oncol. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: J Thorac Oncol. 2019 Aug; 14(8): 1360–1369. Published online 2019 Apr 19. doi: 10.1016/j.jtho.2019.04.008

PMCID:: PMC6833942

Abstract Article PDF–564K

Select item 67848152.

Assessing a single SNP located at TERT/CLPTM1L multi-cancer risk region as a genetic modifier for risk of pancreatic cancer and melanoma in Dutch CDKN2A mutation carriers

E. Christodoulou, M. Visser, T. P. Potjer, N. van der Stoep, M. Rodríguez-Girondo, R. van Doorn, N. Gruis

Fam Cancer. 2019; 18(4): 439–444. Published online 2019 Jun 15. doi: 10.1007/s10689-019-00137-5

PMCID:: PMC6784815

Abstract Article PDF–591K

Select item 58105843.

Clptm1 Limits Forward Trafficking of GABA_A Receptors to Scale Inhibitory Synaptic Strength

Yuan Ge, Yunhee Kang, Robert M. Cassidy, Kyung-Mee Moon, Renate Lewis, Rachel O. L. Wong, Leonard J. Foster, Ann Marie Craig

Neuron. Author manuscript; available in PMC 2019 Feb 7.

Published in final edited form as: Neuron. 2018 Feb 7; 97(3): 596–610.e8. Published online 2018 Jan 25. doi: 10.1016/j.neuron.2017.12.038

PMCID:: PMC5810584

Abstract Article PDF–2.6M

Select item 94697614.

Photochemical Identification of Auxiliary SARS-Cov-2 Host-Entry Factors using μMap

Saori Suzuki, Jacob B. Geri, Steve D. Knutson, Harris Bell-Temin, Tomokazu Tamura, David F. Fernández, Gabby H. Lovett, Nicholas A. Till, Brigitte L. Heller, Jinchao Guo, David W. C. MacMillan, Alexander Ploss

J Am Chem Soc. Author manuscript; available in PMC 2024 Jan 25.

Published in final edited form as: J Am Chem Soc. 2022 Sep 14; 144(36): 16604–16611. Published online 2022 Sep 1. doi: 10.1021/jacs.2c06806

PMCID:: PMC9469761

Abstract Article PDF–1.4M

Select item 35035315.

Testing reported associations of genetic risk factors for oral clefts in a large Irish study population

Tonia C. Carter, Anne M. Molloy, Faith Pangilinan, James F. Troendle, Peadar N. Kirke, Mary R. Conley, David J. A. Orr, Michael Earley, Eamon McKiernan, Ena C. Lynn, Anne Doyle, John M. Scott, Lawrence C. Brody, James L. Mills

Birth Defects Res A Clin Mol Teratol. Author manuscript; available in PMC 2012 Nov 21.

Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2010 Feb; 88(2): 84–93. doi: 10.1002/bdra.20639

PMCID:: PMC3503531

Abstract Article PDF–345K

Select item 42740656.

Genetic loci associated with circulating levels of very long-chain saturated fatty acids

Rozenn N. Lemaitre, Irena B. King, Edmond K. Kabagambe, Jason H. Y. Wu, Barbara McKnight, Ani Manichaikul, Weihua Guan, Qi Sun, Daniel I. Chasman, Millennia Foy, Lu Wang, Jingwen Zhu, David S. Siscovick, Michael Y. Tsai, Donna K. Arnett, Bruce M. Psaty, Luc Djousse, Yii-Der I. Chen, Weihong Tang, Lu-Chen Weng, Hongyu Wu, Majken K. Jensen, Audrey Y. Chu, David R. Jacobs, Jr., Stephen S. Rich, Dariush Mozaffarian, Lyn Steffen, Eric B. Rimm, Frank B. Hu, Paul M. Ridker, Myriam Fornage, Yechiel Friedlander

J Lipid Res. 2015 Jan; 56(1): 176–184. doi: 10.1194/jlr.M052456

PMCID:: PMC4274065

Abstract Article PDF–1.1M

Select item 96239797.

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality

Arti T. Navare, Fred D. Mast, Jean Paul Olivier, Thierry Bertomeu, Maxwell L. Neal, Lindsay N. Carpp, Alexis Kaushansky, Jasmin Coulombe-Huntington, Mike Tyers, John D. Aitchison

J Cell Biol. 2022 Nov 7; 221(11): e202011050. Published online 2022 Oct 28. doi: 10.1083/jcb.202011050

PMCID:: PMC9623979

Abstract Article PDF–3.7M

Select item 62427278.

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development

Meaghan Van Alstyne, Francesco Lotti, Andrea Dal Mas, Estela Area Gomez, Livio Pellizzoni

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Nov 30.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Nov 30; 506(3): 463–470. Published online 2018 Oct 22. doi: 10.1016/j.bbrc.2018.10.073

PMCID:: PMC6242727

Abstract Article PDF–910K

Select item 64618649.

LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition

Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang

Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3

PMCID:: PMC6461864

Abstract Article PDF–11M

Select item 325047910.

Defining human ERAD networks through an integrative mapping strategy

John C. Christianson, James A. Olzmann, Thomas A. Shaler, Mathew E. Sowa, Eric J. Bennett, Caleb M. Richter, Ryan E. Tyler, Ethan J. Greenblatt, J. Wade Harper, Ron R. Kopito

Nat Cell Biol. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Nat Cell Biol. 2012 Jan; 14(1): 93–105. Published online 2011 Nov 27. doi: 10.1038/ncb2383

PMCID:: PMC3250479

Abstract Article PDF–2.7M

Select item 729913011.

IKK-mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5

Jingzi Zhang, Ruoyu Zhao, Christine L. N. Bryant, Kenneth Wu, Zhihong Liu, Yibing Ding, Yue Zhao, Bin Xue, Zhen-Qiang Pan, Chaojun Li, Lan Huang, Lei Fang

J Proteome Res. Author manuscript; available in PMC 2020 Jun 17.

Published in final edited form as: J Proteome Res. 2020 Mar 6; 19(3): 1119–1130. Published online 2020 Feb 3. doi: 10.1021/acs.jproteome.9b00626

PMCID:: PMC7299130

Abstract Article PDF–2.2M

Select item 274057212.

A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication

Man Lung Yeung, Laurent Houzet, Venkat S. R. K. Yedavalli, Kuan-Teh Jeang

J Biol Chem. 2009 Jul 17; 284(29): 19463–19473. Published online 2009 May 20. doi: 10.1074/jbc.M109.010033

PMCID:: PMC2740572

Abstract Article PDF–2.5M

Select item 825771213.

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates

David Schlütermann, Niklas Berleth, Jana Deitersen, Nora Wallot-Hieke, Olena Friesen, Wenxian Wu, Fabian Stuhldreier, Yadong Sun, Lena Berning, Annabelle Friedrich, María José Mendiburo, Christoph Peter, Constanze Wiek, Helmut Hanenberg, Anja Stefanski, Kai Stühler, Björn Stork

Sci Rep. 2021; 11: 13863. Published online 2021 Jul 5. doi: 10.1038/s41598-021-92408-4

PMCID:: PMC8257712

Abstract Article PDF–3.2M

Select item 733229314.

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson

eLife. 2020; 9: e57306. Published online 2020 Jul 2. doi: 10.7554/eLife.57306

PMCID:: PMC7332293

Abstract Article PDF–2.2M

Select item 292822415.

Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity

HD Hosgood, III, L Zhang, M Shen, SI Berndt, R Vermeulen, G Li, S Yin, M Yeager, J Yuenger, N Rothman, S Chanock, M Smith, Q Lan

Occup Environ Med. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: Occup Environ Med. 2009 Dec; 66(12): 848–853. Published online 2009 Sep 22. doi: 10.1136/oem.2008.044024

PMCID:: PMC2928224

Abstract Article PDF–321K

Select item 754235616.

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells

Jaya Bhushan, Joshua B. Radke, Yi-Chieh Perng, Michael Mcallaster, Deborah J. Lenschow, Herbert W. Virgin, L. David Sibley

mBio. 2020 Sep-Oct; 11(5): e00852-20. Published online 2020 Oct 6. doi: 10.1128/mBio.00852-20

PMCID:: PMC7542356

Abstract Article PDF–2.4M

Select item 325365817.

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

Shitao Li, Lingyan Wang, Michael Berman, Young-Yun Kong, Martin E. Dorf

Immunity. Author manuscript; available in PMC 2012 Sep 23.

Published in final edited form as: Immunity. 2011 Sep 23; 35(3): 426–440. Published online 2011 Sep 8. doi: 10.1016/j.immuni.2011.06.014

Correction in:: volume 35 on page 647

PMCID:: PMC3253658

Abstract Article PDF–4.2M

Select item 290133618.

Maternal Genes and Facial Clefts in Offspring: A Comprehensive Search for Genetic Associations in Two Population-Based Cleft Studies from Scandinavia

Astanand Jugessur, Min Shi, Håkon Kristian Gjessing, Rolv Terje Lie, Allen James Wilcox, Clarice Ring Weinberg, Kaare Christensen, Abee Lowman Boyles, Sandra Daack-Hirsch, Truc Trung Nguyen, Lene Christiansen, Andrew Carl Lidral, Jeffrey Clark Murray

PLoS One. 2010; 5(7): e11493. Published online 2010 Jul 9. doi: 10.1371/journal.pone.0011493

PMCID:: PMC2901336

Abstract Article PDF–778K

Select item 764232719.

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

Dick J. H. van den Boomen, Agata Sienkiewicz, Ilana Berlin, Marlieke L. M. Jongsma, Daphne M. van Elsland, J. Paul Luzio, Jacques J. C. Neefjes, Paul J. Lehner

Nat Commun. 2020; 11: 5559. Published online 2020 Nov 3. doi: 10.1038/s41467-020-19032-0

PMCID:: PMC7642327

Abstract Article PDF–12M

Select item 799307620.

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor

Jin-Gu Lee, Weiliang Huang, Hangnoh Lee, Joyce van de Leemput, Maureen A. Kane, Zhe Han

Cell Biosci. 2021; 11: 58. Published online 2021 Mar 25. doi: 10.1186/s13578-021-00568-7

PMCID:: PMC7993076

Abstract Article PDF–2.0M

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