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Select item 103986691.

Arginase 1 and L‐arginine coordinate fetal lung development and the initiation of labor in mice

Yaqin Yu, Yuanyuan Liu, Xuesong Sui, Yanyu Sui, Zhe Wang, Carole R Mendelson, Lu Gao

EMBO Rep. 2023 Aug; 24(8): e56352. Published online 2023 Jun 9. doi: 10.15252/embr.202256352

PMCID:: PMC10398669

Abstract Article PDF–12M

Select item 103444242.

Inhibitory IL-10-producing CD4⁺ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1

Mathew Clement, Kristin Ladell, Kelly L Miners, Morgan Marsden, Lucy Chapman, Anna Cardus Figueras, Jake Scott, Robert Andrews, Simon Clare, Valeriia V Kriukova, Ksenia R Lupyr, Olga V Britanova, David R Withers, Simon A Jones, Dmitriy M Chudakov, David A Price, Ian R Humphreys

eLife. 2023; 12: e79165. Published online 2023 Jul 13. doi: 10.7554/eLife.79165

PMCID:: PMC10344424

Abstract Article PDF–24M

Select item 102441743.

ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain

Vassilis Stratoulias, Rocío Ruiz, Shigeaki Kanatani, Ahmed M. Osman, Lily Keane, Jose A. Armengol, Antonio Rodríguez-Moreno, Adriana-Natalia Murgoci, Irene García-Domínguez, Isabel Alonso-Bellido, Fernando González Ibáñez, Katherine Picard, Guillermo Vázquez-Cabrera, Mercedes Posada-Pérez, Nathalie Vernoux, Dario Tejera, Kathleen Grabert, Mathilde Cheray, Patricia González-Rodríguez, Eva M. Pérez-Villegas, Irene Martínez-Gallego, Alejandro Lastra-Romero, David Brodin, Javier Avila-Cariño, Yang Cao, Mikko Airavaara, Per Uhlén, Michael T. Heneka, Marie-Ève Tremblay, Klas Blomgren, Jose L. Venero, Bertrand Joseph

Nat Neurosci. 2023; 26(6): 1008–1020. Published online 2023 May 11. doi: 10.1038/s41593-023-01326-3

PMCID:: PMC10244174

Abstract Article PDF–17M

Select item 102059854.

Chronic anemia is associated with systemic endothelial dysfunction

Ramesh Chennupati, Isabella Solga, Patricia Wischmann, Paul Dahlmann, Feyza Gül Celik, Daniela Pacht, Aslıhan Şahin, Vithya Yogathasan, Mohammad Rabiul Hosen, Norbert Gerdes, Malte Kelm, Christian Jung

Front Cardiovasc Med. 2023; 10: 1099069. Published online 2023 May 10. doi: 10.3389/fcvm.2023.1099069

PMCID:: PMC10205985

Abstract Article PDF–4.3M

Select item 101372695.

Timing of Interleukin-4 Stimulation of Macrophages Determines Their Anti-Microbial Activity during Infection with Salmonella enterica Serovar Typhimurium

Natascha Brigo, Emely Neumaier, Christa Pfeifhofer-Obermair, Philipp Grubwieser, Sabine Engl, Sylvia Berger, Markus Seifert, Vera Reinstadler, Herbert Oberacher, Günter Weiss

Cells. 2023 Apr; 12(8): 1164. Published online 2023 Apr 14. doi: 10.3390/cells12081164

PMCID:: PMC10137269

Abstract Article PDF–9.2M

Select item 100012886.

Methylglyoxal-Modified Albumin Effects on Endothelial Arginase Enzyme and Vascular Function

Ebaa M. Alzayadneh, Alia Shatanawi, R. William Caldwell, Ruth B. Caldwell

Cells. 2023 Mar; 12(5): 795. Published online 2023 Mar 3. doi: 10.3390/cells12050795

PMCID:: PMC10001288

Abstract Article PDF–2.0M

Select item 91617877.

Arginase-1 Is Required for Macrophage-Mediated Renal Tubule Regeneration

Naomi S. Shin, Arnaud Marlier, Leyuan Xu, Natnael Doilicho, Daniel Linberg, Jiankan Guo, Lloyd G. Cantley

J Am Soc Nephrol. 2022 Jun; 33(6): 1077–1086. Published online 2022 Jun. doi: 10.1681/ASN.2021121548

PMCID:: PMC9161787

Abstract Article

Select item 85174808.

Murine Susceptibility to Leishmania amazonensis Infection Is Influenced by Arginase-1 and Macrophages at the Lesion Site

Fernanda Tomiotto-Pellissier, Milena Menegazzo Miranda-Sapla, Taylon Felipe Silva, Bruna Taciane da Silva Bortoleti, Manoela Daiele Gonçalves, Virginia Márcia Concato, Ana Carolina Jacob Rodrigues, Mariana Barbosa Detoni, Larissa Staurengo-Ferrari, Waldiceu Aparecido Verri, Jr, Idessania Nazareth Costa, Carolina Panis, Ivete Conchon-Costa, Juliano Bordignon, Wander Rogério Pavanelli

Front Cell Infect Microbiol. 2021; 11: 687633. Published online 2021 Oct 1. doi: 10.3389/fcimb.2021.687633

Correction in:: Front Cell Infect Microbiol. 2021; 11: 804809.

PMCID:: PMC8517480

Abstract Article PDF–4.5M

Select item 78555749.

Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia

Dalia Haydar, Rene Gonzalez, Beth A. Garvy, Sylvie Garneau-Tsodikova, Nishad Thamban Chandrika, Therese J. Bocklage, David J. Feola

Immunobiology. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Immunobiology. 2021 Jan; 226(1): 152034. Published online 2020 Nov 24. doi: 10.1016/j.imbio.2020.152034

PMCID:: PMC7855574

Abstract Article PDF–1.7M

Select item 710929010.

HuangqiGuizhiWuwu Decoction Prevents Vascular Dysfunction in Diabetes via Inhibition of Endothelial Arginase 1

Hong Cheng, Tian Lu, Jingya Wang, Yucen Xia, Xiaoshu Chai, Minyi Zhang, Yutong Yao, Na Zhou, Sisi Zhou, Xinyi Chen, Weiwei Su, Cunzhi Liu, Wei Yi, Yongjun Chen, Lin Yao

Front Physiol. 2020; 11: 201. Published online 2020 Mar 25. doi: 10.3389/fphys.2020.00201

Correction in:: Front Physiol. 2021; 12: 650179.

PMCID:: PMC7109290

Abstract Article PDF–5.1M

Select item 677790911.

Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development

Xiao-Bo Liu, Jillian R. Haney, Gloria Cantero, Jenna R. Lambert, Marcos Otero-Garcia, Brian Truong, Andrea Gropman, Inma Cobos, Stephen D. Cederbaum, Gerald S. Lipshutz

JCI Insight. 2019 Sep 5; 4(17): e130260. Published online 2019 Sep 5. doi: 10.1172/jci.insight.130260

PMCID:: PMC6777909

Abstract Article PDF–14M

Select item 648440212.

IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1

Eleonora Panfili, Giada Mondanelli, Ciriana Orabona, Roberta Bianchi, Marco Gargaro, Francesca Fallarino, Paolo Puccetti, Ursula Grohmann, Claudia Volpi, Maria Laura Belladonna

J Cell Mol Med. 2019 May; 23(5): 3757–3761. Published online 2019 Feb 22. doi: 10.1111/jcmm.14215

PMCID:: PMC6484402

Abstract Article PDF–332K

Select item 641095313.

Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1

Anil Bhatta, Lin Yao, Zhimin Xu, Haroldo A. Toque, Jijun Chen, Reem T. Atawia, Abdelrahman Y. Fouda, Zsolt Bagi, Rudolf Lucas, Ruth B. Caldwell, Robert W. Caldwell

Cardiovasc Res. 2017 Nov; 113(13): 1664–1676. Published online 2017 Sep 7. doi: 10.1093/cvr/cvx164

Correction in:: Cardiovasc Res. 2018 Jan 1; 114(1): 64.

PMCID:: PMC6410953

Abstract Article PDF–1.1M

Select item 629943014.

Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages

Sean P. Arlauckas, Seth B. Garren, Chris S. Garris, Rainer H. Kohler, Juhyun Oh, Mikael J. Pittet, Ralph Weissleder

Theranostics. 2018; 8(21): 5842–5854. Published online 2018 Nov 12. doi: 10.7150/thno.26888

PMCID:: PMC6299430

Abstract Article PDF–2.4M

Select item 601365915.

Arginase-1 Expression in Myeloid Cells Regulates Staphylococcus aureus Planktonic but Not Biofilm Infection

Kelsey J. Yamada, Cortney E. Heim, Amy L. Aldrich, Casey M. Gries, Anna G. Staudacher, Tammy Kielian

Infect Immun. 2018 Jul; 86(7): e00206-18. Prepublished online 2018 Apr 16. Published online 2018 Jun 21. doi: 10.1128/IAI.00206-18

PMCID:: PMC6013659

Abstract Article PDF–1.0M

Select item 599750816.

Arginase-1 is neither constitutively expressed in nor required for myeloid-derived suppressor cell (MDSC)-mediated inhibition of T cell proliferation

Zhen Bian, Ahmed Mansour Abdelaal, Lei Shi, Hongwei Liang, Lanqiao Xiong, Koby Kidder, Mahathi Venkataramani, Courtney Culpepper, Ke Zen, Yuan Liu

Eur J Immunol. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Eur J Immunol. 2018 Jun; 48(6): 1046–1058. Published online 2018 Mar 23. doi: 10.1002/eji.201747355

PMCID:: PMC5997508

Abstract Article PDF–1.3M

Select item 599530917.

Deletion of endothelial arginase 1 does not improve vasomotor function in diabetic mice

Ramesh Chennupati, Merlijn J. Meens, Ben J. Janssen, Paul van Dijk, Theodorus B. M. Hakvoort, Wouter H. Lamers, Jo G. R. De Mey, S. Eleonore Koehler

Physiol Rep. 2018 Jun; 6(11): e13717. Published online 2018 Jun 10. doi: 10.14814/phy2.13717

PMCID:: PMC5995309

Abstract Article PDF–1.5M

Select item 597961018.

Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1

Esraa Shosha, Zhimin Xu, S. Priya Narayanan, Tahira Lemtalsi, Abdelrahman Y. Fouda, Modesto Rojas, Ji Xing, David Fulton, R. William Caldwell, Ruth B. Caldwell

Int J Mol Sci. 2018 Apr; 19(4): 1215. Published online 2018 Apr 17. doi: 10.3390/ijms19041215

PMCID:: PMC5979610

Abstract Article PDF–9.2M

Select item 579214719.

Obesity-induced vascular inflammation involves elevated arginase activity

Lin Yao, Anil Bhatta, Zhimin Xu, Jijun Chen, Haroldo A. Toque, Yongjun Chen, Yimin Xu, Zsolt Bagi, Rudolf Lucas, Yuqing Huo, Ruth B. Caldwell, R. William Caldwell

Am J Physiol Regul Integr Comp Physiol. 2017 Nov 1; 313(5): R560–R571. Published online 2017 Aug 23. doi: 10.1152/ajpregu.00529.2016

PMCID:: PMC5792147

Abstract Article

Select item 502747420.

Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling

Bomi Lee, Cheng-Ying Wu, Yi-Wei Lin, Sung Wook Park, Li-Na Wei

Nucleic Acids Res. 2016 Sep 19; 44(16): 7568–7579. Published online 2016 May 10. doi: 10.1093/nar/gkw392

PMCID:: PMC5027474

Abstract Article PDF–2.1M

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