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Select item 72616531.

Acute bout of exercise downregulates thioredoxin‐interacting protein expression in rat contracting skeletal muscles

Song‐Gyu Ra, Emi Kawamoto, Keiichi Koshinaka, Maiko Iwabe, Yuki Tomiga, Hiroki Iizawa, Hiroki Honda, Yasuki Higaki, Kentaro Kawanaka

Physiol Rep. 2020 Jun; 8(11): e14388. Published online 2020 May 31. doi: 10.14814/phy2.14388

PMCID:: PMC7261653

Abstract Article PDF–758K

Select item 64899582.

Acupuncture inhibits TXNIP‐associated oxidative stress and inflammation to attenuate cognitive impairment in vascular dementia rats

Si‐Qi Du, Xue‐Rui Wang, Wen Zhu, Yang Ye, Jing‐Wen Yang, Si‐Ming Ma, Cai‐Shuo Ji, Cun‐Zhi Liu

CNS Neurosci Ther. 2018 Jan; 24(1): 39–46. Published online 2017 Nov 6. doi: 10.1111/cns.12773

PMCID:: PMC6489958

Abstract Article PDF–1.0M

Select item 56580063.

Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: Implications for diabetic retinopathy

Takhellambam S. Devi, Ken-Ichi Hosoya, Tetsuya Terasaki, Lalit P. Singh

Exp Cell Res. Author manuscript; available in PMC 2017 Oct 26.

Published in final edited form as: Exp Cell Res. 2013 Apr 15; 319(7): 1001–1012. Published online 2013 Jan 24. doi: 10.1016/j.yexcr.2013.01.012

PMCID:: PMC5658006

Abstract Article PDF–1.4M

Select item 55207114.

TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy

Takhellambam Swornalata Devi, Mallika Somayajulu, Renu Anjan Kowluru, Lalit Pukhrambam Singh

Cell Death Dis. 2017 May; 8(5): e2777. Published online 2017 May 11. doi: 10.1038/cddis.2017.190

PMCID:: PMC5520711

Abstract Article PDF–6.8M

Select item 54260695.

Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage

Qing Zhao, Xudong Che, Hongxia Zhang, Pianpian Fan, Guanping Tan, Liu Liu, Dengzhi Jiang, Jun Zhao, Xiang Xiang, Yidan Liang, Xiaochuan Sun, Zhaohui He

J Neuroinflammation. 2017; 14: 104. Published online 2017 May 11. doi: 10.1186/s12974-017-0878-6

PMCID:: PMC5426069

Abstract Article PDF–3.1M

Select item 54124386.

Thioredoxin-Interacting Protein Mediates Apoptosis in Early Brain Injury after Subarachnoid Haemorrhage

Qing Zhao, Xudong Che, Hongxia Zhang, Guanping Tan, Liu Liu, Dengzhi Jiang, Jun Zhao, Xiang Xiang, Xiaochuan Sun, Zhaohui He

Int J Mol Sci. 2017 Apr; 18(4): 854. Published online 2017 Apr 18. doi: 10.3390/ijms18040854

PMCID:: PMC5412438

Abstract Article PDF–5.7M

Select item 39472897.

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

Islam N. Mohamed, Sherif S. Hafez, Arwa Fairaq, Adviye Ergul, John D. Imig, Azza B. El-Remessy

Diabetologia. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Diabetologia. 2014 Feb; 57(2): 413–423. Published online 2013 Nov 8. doi: 10.1007/s00125-013-3101-z

PMCID:: PMC3947289

Abstract Article PDF–2.7M

Select item 38317138.

Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats

Wei Wang, Chuang Wang, Xiao-Qin Ding, Ying Pan, Ting-Ting Gu, Ming-Xing Wang, Yang-Liu Liu, Fu-Meng Wang, Shui-Juan Wang, Ling-Dong Kong

Br J Pharmacol. 2013 Jul; 169(6): 1352–1371. Published online 2013 Jun 21. doi: 10.1111/bph.12226

Correction in:: Br J Pharmacol. 2022 Jun; 179(11): 2785–2786.

PMCID:: PMC3831713

Abstract Article PDF–5.5M

Select item 38231489.

Acute hyperglycaemia enhances oxidative stress and aggravates myocardial ischaemia/reperfusion injury: role of thioredoxin-interacting protein

Hui Su, Lele Ji, Wenjuan Xing, Wei Zhang, Heping Zhou, Xinhong Qian, Xiaoming Wang, Feng Gao, Xin Sun, Haifeng Zhang

J Cell Mol Med. 2013 Jan; 17(1): 181–191. Published online 2013 Jan 11. doi: 10.1111/j.1582-4934.2012.01661.x

PMCID:: PMC3823148

Abstract Article PDF–867K

Select item 331358210.

TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy

Takhellambam S. Devi, Icksoo Lee, Maik Hüttemann, Ashok Kumar, Kwaku D. Nantwi, Lalit P. Singh

Exp Diabetes Res. 2012; 2012: 438238. Published online 2012 Mar 18. doi: 10.1155/2012/438238

PMCID:: PMC3313582

Abstract Article PDF–4.6M

Select item 317186911.

Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity

Mohammed MH Al-Gayyar, Mohammed A Abdelsaid, Suraporn Matragoon, Bindu A Pillai, Azza B El-Remessy

Br J Pharmacol. 2011 Sep; 164(1): 170–180. doi: 10.1111/j.1476-5381.2011.01336.x

PMCID:: PMC3171869

Abstract Article PDF–1.4M

Select item 303252712.

Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

L Perrone, T S Devi, K-I Hosoya, T Terasaki, L P Singh

Cell Death Dis. 2010 Aug; 1(8): e65. Published online 2010 Aug 19. doi: 10.1038/cddis.2010.42

PMCID:: PMC3032527

Abstract Article PDF–760K

Select item 1043536113.

SRY-box transcription factor 9 modulates Müller cell gliosis in diabetic retinopathy by upregulating TXNIP transcription

Sheng Li, Gaoxiang Ouyang, Linhui Yuan, Xiaoxuan Wu, Lijun Zhang

Exp Anim. 2023; 72(3): 302–313. Published online 2023 Jan 16. doi: 10.1538/expanim.22-0126

PMCID:: PMC10435361

Abstract Article PDF–3.0M

Select item 909571114.

Energy restriction induced SIRT6 inhibits microglia activation and promotes angiogenesis in cerebral ischemia via transcriptional inhibition of TXNIP

Ming-Yu Song, Fang Yi, Hui Xiao, Jun Yin, Qing Huang, Jian Xia, Xiao-Meng Yin, Yan-Bin Wen, Le Zhang, Yun-Hai Liu, Bo Xiao, Wen-Ping Gu

Cell Death Dis. 2022 May; 13(5): 449. Published online 2022 May 11. doi: 10.1038/s41419-022-04866-x

PMCID:: PMC9095711

Abstract Article PDF–6.0M

Select item 880687815.

Circular RNA SMEK1 promotes neuropathic pain in rats through targeting microRNA-216a-5p to mediate Thioredoxin Interacting Protein (TXNIP) expression

Yufu Xin, Xinrong Song, Qingye Ge

Bioengineered. 2021; 12(1): 5540–5551. Published online 2021 Sep 14. doi: 10.1080/21655979.2021.1965811

PMCID:: PMC8806878

Abstract Article PDF–2.1M

Select item 822235316.

TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression

Xiang Zhang, Song Zhao, Qingqing Yuan, Lin Zhu, Fan Li, Hui Wang, Dezhi Kong, Jun Hao

Cell Death Dis. 2021 Jul; 12(7): 642. Published online 2021 Jun 23. doi: 10.1038/s41419-021-03930-2

PMCID:: PMC8222353

Abstract Article PDF–5.1M

Select item 696472117.

Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats

Jing Yu, Wen-na Wang, Nathanael Matei, Xue Li, Jin-wei Pang, Jun Mo, Sheng-pan Chen, Ji-ping Tang, Min Yan, John H. Zhang

Oxid Med Cell Longev. 2020; 2020: 4717258. Published online 2020 Jan 3. doi: 10.1155/2020/4717258

PMCID:: PMC6964721

Abstract Article PDF–3.5M

Select item 660564118.

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction

Chun Yang, Wan Xia, Xiaolin Liu, Jian Lin, Aiping Wu

Int J Mol Med. 2019 Aug; 44(2): 417–426. Published online 2019 Jun 6. doi: 10.3892/ijmm.2019.4232

PMCID:: PMC6605641

Abstract Article PDF–1.2M

Select item 648816919.

Role of the thioredoxin interacting protein in diabetic nephropathy and the mechanism of regulating NOD-like receptor protein 3 inflammatory corpuscle

Chunmei Gu, Shumei Liu, Hongyue Wang, Haichuan Dou

Int J Mol Med. 2019 Jun; 43(6): 2440–2450. Published online 2019 Apr 11. doi: 10.3892/ijmm.2019.4163

PMCID:: PMC6488169

Abstract Article PDF–970K

Select item 493392820.

Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway

Chunling Huang, Yuan Zhang, Darren J. Kelly, Christina Y. R. Tan, Anthony Gill, Delfine Cheng, Filip Braet, Jin-Sung Park, Carolyn M. Sue, Carol A. Pollock, Xin-Ming Chen

Sci Rep. 2016; 6: 29196. Published online 2016 Jul 6. doi: 10.1038/srep29196