U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from Gene

Items: 1 to 20 of 64

1.
First selective 12-LOX inhibitor, ML355, impairs thrombus formation and vessel occlusion in vivo with minimal effects on hemostasis
Reheman Adili, Benjamin E. Tourdot, Katherine Mast, Jennifer Yeung, John Cody Freedman, Abigail Green, Diane K. Luci, Ajit Jadhav, Anton Simeonov, David J. Maloney, Theodore R Holman, Michael Holinstat
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Oct; 37(10): 1828–1839. Published online 2017 Aug 3. doi: 10.1161/ATVBAHA.117.309868
PMCID:
PMC5620123
AbstractArticlePDF–2.3M
2.
CYP2J2 Targeting to Endothelial Cells Attenuates Adiposity and Vascular Dysfunction in Mice Fed a High-Fat Diet by Reprogramming Adipocyte Phenotype
Nader G. Abraham, Komal Sodhi, Anne M. Silvis, Luca Vanella, Gaia Favero, Rita Rezzani, Craig Lee, Darryl C. Zeldin, Michal L. Schwartzman
Hypertension. Author manuscript; available in PMC 2015 Dec 1.
Published in final edited form as: Hypertension. 2014 Dec; 64(6): 1352–1361. Published online 2014 Sep 22. doi: 10.1161/HYPERTENSIONAHA.114.03884
PMCID:
PMC4230994
AbstractArticlePDF–1.2M
3.
ROLE OF 12/15-LIPOXYGENASE IN NITROSATIVE STRESS AND PERIPHERAL PREDIABETIC AND DIABETIC NEUROPATHIES
Roman Stavniichuk, Viktor R. Drel, Hanna Shevalye, Igor Vareniuk, Martin J. Stevens, Jerry L. Nadler, Irina G. Obrosova
Free Radic Biol Med. Author manuscript; available in PMC 2011 Sep 15.
Published in final edited form as: Free Radic Biol Med. 2010 Sep 15; 49(6): 1036–1045. Published online 2010 Jun 22. doi: 10.1016/j.freeradbiomed.2010.06.016
PMCID:
PMC3056543
AbstractArticlePDF–967K
4.
Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis
Alexander Queck, Annika F. Fink, Evelyn Sirait-Fischer, Sabrina Rüschenbaum, Dominique Thomas, Ryan G. Snodgrass, Gerd Geisslinger, Hideo A. Baba, Jonel Trebicka, Stefan Zeuzem, Andreas Weigert, Christian M. Lange, Bernhard Brüne
Front Immunol. 2020; 11: 1447. Published online 2020 Jul 14. doi: 10.3389/fimmu.2020.01447
PMCID:
PMC7371948
AbstractArticlePDF–3.7M
5.
Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells
Abass M. Conteh, Christopher A. Reissaus, Marimar Hernandez-Perez, Swetha Nakshatri, Ryan M. Anderson, Raghavendra G. Mirmira, Sarah A. Tersey, Amelia K. Linnemann
J Biol Chem. 2019 Apr 19; 294(16): 6612–6620. Published online 2019 Feb 21. doi: 10.1074/jbc.RA118.007102
PMCID:
PMC6484126
AbstractArticlePDF–2.0M
6.
Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis
Sarah N. Lauder, Keith Allen-Redpath, David A. Slatter, Maceler Aldrovandi, Anne O’Connor, Daniel Farewell, Charles L. Percy, Jessica E. Molhoek, Sirpa Rannikko, Victoria J. Tyrrell, Salvatore Ferla, Ginger L. Milne, Alastair W. Poole, Christopher P. Thomas, Samya Obaji, Philip R. Taylor, Simon A. Jones, Phillip G. de Groot, Rolf T. Urbanus, Sohvi Hörkkö, Stefan Uderhardt, Jochen Ackermann, P. Vince Jenkins, Andrea Brancale, Gerhard Krönke, Peter W. Collins, Valerie B. O’Donnell
Sci Signal. Author manuscript; available in PMC 2017 Dec 7.
Published in final edited form as: Sci Signal. 2017 Nov 28; 10(507): eaan2787. Published online 2017 Nov 28. doi: 10.1126/scisignal.aan2787
PMCID:
PMC5720345
AbstractArticlePDF–3.0M
7.
Reduced Dietary Omega-6 to Omega-3 Fatty Acid Ratio and 12/15-Lipoxygenase Deficiency Are Protective against Chronic High Fat Diet-Induced Steatohepatitis
Milos Lazic, Maria Eugenia Inzaugarat, Davide Povero, Iris C. Zhao, Mark Chen, Madlena Nalbandian, Yury I. Miller, Alejandra C. Cherñavsky, Ariel E. Feldstein, Dorothy D. Sears
PLoS One. 2014; 9(9): e107658. Published online 2014 Sep 24. doi: 10.1371/journal.pone.0107658
PMCID:
PMC4175074
AbstractArticlePDF–3.6M
8.
Structure Based Design and Synthesis of Peptide Inhibitor of Human LOX-12: In Vitro and In Vivo Analysis of a Novel Therapeutic Agent for Breast Cancer
Abhay kumar Singh, Ratnakar Singh, Farhat Naz, Shyam Singh Chauhan, Amit Dinda, Abhay Anand Shukla, Kamaldeep Gill, Vaishali Kapoor, Sharmistha Dey
PLoS One. 2012; 7(2): e32521. Published online 2012 Feb 23. doi: 10.1371/journal.pone.0032521
PMCID:
PMC3285689
AbstractArticlePDF–497K
9.
EGF Stimulates Lipoxin A4 Synthesis and Modulates Repair in Corneal Epithelial Cells through ERK and p38 Activation
Sachidananda Kenchegowda, Nicolas G. Bazan, Haydee E. P. Bazan
Invest Ophthalmol Vis Sci. 2011 Apr; 52(5): 2240–2249. Published online 2011 Apr 6. doi: 10.1167/iovs.10-6199
PMCID:
PMC3080170
AbstractArticlePDF–2.0M
10.
Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway
Han-A Park, Savita Khanna, Cameron Rink, Surya Gnyawali, Sashwati Roy, Chandan K. Sen
Cell Death Differ. Author manuscript; available in PMC 2010 Nov 23.
Published in final edited form as: Cell Death Differ. 2009 Aug; 16(8): 1167–1179. Published online 2009 Apr 17. doi: 10.1038/cdd.2009.37
PMCID:
PMC2990696
AbstractArticlePDF–1.4M
11.
p63 directly induces expression of Alox12, a regulator of epidermal barrier formation
Soeun Kim, Irene F. Choi, Jessica R. Quante, Lei Zhang, Dennis R. Roop, Maranke I. Koster
Exp Dermatol. Author manuscript; available in PMC 2010 Apr 20.
Published in final edited form as: Exp Dermatol. 2009 Dec; 18(12): 1016–1021. doi: 10.1111/j.1600-0625.2009.00894.x
PMCID:
PMC2857403
AbstractArticlePDF–1.0M
12.
Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice
David Bleich, Songyuan Chen, Brian Zipser, Duxin Sun, Colin D. Funk, Jerry L. Nadler
J Clin Invest. 1999 May 15; 103(10): 1431–1436. doi: 10.1172/JCI5241
PMCID:
PMC408453
AbstractArticlePDF–242K
13.
Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase
Eric N. Johnson, Lawrence F. Brass, Colin D. Funk
Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6): 3100–3105. doi: 10.1073/pnas.95.6.3100
PMCID:
PMC19701
AbstractArticlePDF–238K
14.
Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity
Keith Allen-Redpath, Maceler Aldrovandi, Sarah N. Lauder, Anastasia Gketsopoulou, Victoria J. Tyrrell, David A. Slatter, Robert Andrews, W. John Watkins, Georgia Atkinson, Eileen McNeill, Anna Gilfedder, Majd Protty, James Burston, Sam R. C. Johnson, Patricia R. S. Rodrigues, Dylan O. Jones, Regent Lee, Ashok Handa, Keith Channon, Samya Obaji, Jorge Alvarez-Jarreta, Gerhard Krönke, Jochen Ackermann, P. Vince Jenkins, Peter W. Collins, Valerie B. O’Donnell
Proc Natl Acad Sci U S A. 2019 Apr 16; 116(16): 8038–8047. Published online 2019 Apr 3. doi: 10.1073/pnas.1814409116
PMCID:
PMC6475397
AbstractArticlePDF–1.9M
15.
12-HETrE, a 12-LOX oxylipin of DGLA, inhibits thrombosis via Gαs signaling in platelets
Jennifer Yeung, Benjamin E. Tourdot, Reheman Adili, Abigail R. Green, Cody J. Freedman, Pilar Fernandez-Perez, Johnny Yu, Theodore R. Holman, Michael Holinstat
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Oct; 36(10): 2068–2077. Published online 2016 Jul 28. doi: 10.1161/ATVBAHA.116.308050
PMCID:
PMC5488693
AbstractArticlePDF–1.0M
16.
5-Lipoxygenase, but Not 12/15-Lipoxygenase, Contributes to Degeneration of Retinal Capillaries in a Mouse Model of Diabetic Retinopathy
Rose A. Gubitosi-Klug, Ramaprasad Talahalli, Yunpeng Du, Jerry L. Nadler, Timothy S. Kern
Diabetes. Author manuscript; available in PMC 2015 May 26.
Published in final edited form as: Diabetes. 2008 May; 57(5): 1387–1393. Published online 2008 Mar 17. doi: 10.2337/db07-1217
PMCID:
PMC4444435
AbstractArticlePDF–1004K
17.
Following experimental stroke, the recovering brain is vulnerable to lipoxygenase-dependent semaphorin signaling
Anton Pekcec, Kazim Yigitkanli, Joo Eun Jung, Stefanie Pallast, Changhong Xing, Alexander Antipenko, Maria Minchenko, Dimitar B. Nikolov, Theodore R. Holman, Eng H. Lo, Klaus van Leyen
FASEB J. 2013 Feb; 27(2): 437–445. doi: 10.1096/fj.12-206896
PMCID:
PMC3545523
AbstractArticle
18.
Smooth Muscle-specific Expression of Calcium-independent Phospholipase A2β (iPLA2β) Participates in the Initiation and Early Progression of Vascular Inflammation and Neointima Formation
Shu Liu, Zhongwen Xie, Qingwei Zhao, Huan Pang, John Turk, Lindsay Calderon, Wen Su, Guogang Zhao, Haifei Xu, Ming C. Gong, Zhenheng Guo
J Biol Chem. 2012 Jul 13; 287(29): 24739–24753. Published online 2012 May 25. doi: 10.1074/jbc.M112.340216
PMCID:
PMC3397901
AbstractArticlePDF–3.1M
19.
Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors
Ann M. Gregus, Suzanne Doolen, Darren S. Dumlao, Matthew W. Buczynski, Toshifumi Takasusuki, Bethany L. Fitzsimmons, Xiao-Ying Hua, Bradley K. Taylor, Edward A. Dennis, Tony L. Yaksh
Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17): 6721–6726. Published online 2012 Apr 9. doi: 10.1073/pnas.1110460109
PMCID:
PMC3340022
AbstractArticlePDF–751K
20.
12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response
Banumathi K. Cole, Norine S. Kuhn, Shamina M. Green-Mitchell, Kendall A. Leone, Rebekah M. Raab, Jerry L. Nadler, Swarup K. Chakrabarti
Am J Physiol Endocrinol Metab. 2012 Mar 15; 302(6): E654–E665. Published online 2012 Jan 3. doi: 10.1152/ajpendo.00373.2011
PMCID:
PMC3311293
AbstractArticle

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center