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Items: 13

Select item 54362911.

Prognostic role of TPL2 in early-stage non-small cell lung cancer

Laura Boldrini, Mirella Giordano, Adele Servadio, Cristina Niccoli, Pietro Bertoglio, Marco Lucchi, Franca Melfi, Alfredo Mussi, Gabriella Fontanini

Mol Med Rep. 2017 Jun; 15(6): 3451–3458. Published online 2017 Apr 3. doi: 10.3892/mmr.2017.6430

PMCID:: PMC5436291

Abstract Article PDF–1.1M

Select item 2377982.

Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion.

A Makris, C Patriotis, S E Bear, P N Tsichlis

J Virol. 1993 Jul; 67(7): 4283–4289. doi: 10.1128/jvi.67.7.4283-4289.1993

PMCID:: PMC237798

Summary Page Browse PDF–1.4M

Select item 460643.

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation.

C Patriotis, A Makris, S E Bear, P N Tsichlis

Proc Natl Acad Sci U S A. 1993 Mar 15; 90(6): 2251–2255. doi: 10.1073/pnas.90.6.2251

PMCID:: PMC46064

Summary Page Browse PDF–1.4M

Select item 46427814.

Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice

Xinli Li, Chun Liu, Blanche C. Ip, Kang-Quan Hu, Donald E. Smith, Andrew S. Greenberg, Xiang-Dong Wang

J Exp Clin Cancer Res. 2015; 34: 138. Published online 2015 Nov 11. doi: 10.1186/s13046-015-0254-2

PMCID:: PMC4642781

Abstract Article PDF–1.5M

Select item 45246235.

Tumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8⁺ T Cell Responses and Protects against Influenza Virus

Teneema Kuriakose, Ralph A. Tripp, Wendy T. Watford

PLoS Pathog. 2015 Aug; 11(8): e1005038. Published online 2015 Aug 4. doi: 10.1371/journal.ppat.1005038

PMCID:: PMC4524623

Abstract Article PDF–1.6M

Select item 34593216.

Mutational Activation of the MAP3K8 Protooncogene in Lung Cancer

Adam Michael Clark, Steven H. Reynolds, Marshall Anderson, Jonathan S. Wiest

Genes Chromosomes Cancer. Author manuscript; available in PMC 2012 Sep 27.

Published in final edited form as: Genes Chromosomes Cancer. 2004 Oct; 41(2): 99–108. doi: 10.1002/gcc.20069

PMCID:: PMC3459321

Abstract Article PDF–2.2M

Select item 36316187.

TPL2 kinase is a suppressor of lung carcinogenesis

Katerina Gkirtzimanaki, Kalliopi K. Gkouskou, Urszula Oleksiewicz, Georgios Nikolaidis, Dimitra Vyrla, Michalis Liontos, Vassiliki Pelekanou, Dimitris C. Kanellis, Kostantinos Evangelou, Efstathios N. Stathopoulos, John K. Field, Philip N. Tsichlis, Vassilis Gorgoulis, Triantafillos Liloglou, Aristides G. Eliopoulos

Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16): E1470–E1479. Published online 2013 Mar 26. doi: 10.1073/pnas.1215938110

PMCID:: PMC3631618

Abstract Article PDF–1.7M

Select item 34844498.

Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis

Vasiliki Koliaraki, Manolis Roulis, George Kollias

J Clin Invest. 2012 Nov 1; 122(11): 4231–4242. Published online 2012 Oct 15. doi: 10.1172/JCI63917

PMCID:: PMC3484449

Abstract Article PDF–5.6M

Select item 33449979.

Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apc^min mice by inhibiting IL-10 secretion and regulatory T-cell generation

Oksana B. Serebrennikova, Christos Tsatsanis, Changchuin Mao, Elias Gounaris, Wenying Ren, Linda D. Siracusa, Aristides G. Eliopoulos, Khashayarsha Khazaie, Philip N. Tsichlis

Proc Natl Acad Sci U S A. 2012 May 1; 109(18): E1082–E1091. Published online 2012 Mar 26. doi: 10.1073/pnas.1115098109

PMCID:: PMC3344997

Abstract Article PDF–2.1M

Select item 497239610.

TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control T_H2-Mediated Immunopathology

Yashaswini Kannan, Jimena Perez-Lloret, Yanda Li, Lewis J. Entwistle, Hania Khoury, Stamatia Papoutsopoulou, Radma Mahmood, Nuha R. Mansour, Stanley Ching-Cheng Huang, Edward J. Pearce, Luiz Pedro S. de Carvalho, Steven C. Ley, Mark S. Wilson

PLoS Pathog. 2016 Aug; 12(8): e1005783. Published online 2016 Aug 3. doi: 10.1371/journal.ppat.1005783