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Select item 112557611.

Differential Downregulation of β₁‐Adrenergic Receptor Signaling in the Heart

Bing Xu, Sherif Bahriz, Victoria R. Salemme, Ying Wang, Chaoqun Zhu, Meimi Zhao, Yang K. Xiang

J Am Heart Assoc. 2024 Jun 18; 13(12): e033733. Published online 2024 Jun 11. doi: 10.1161/JAHA.123.033733

PMCID:: PMC11255761

Abstract Article PDF–12M

Select item 67851352.

β1-adrenergic receptors mediate plasma acyl-ghrelin elevation and depressive-like behavior induced by chronic psychosocial stress

Deepali Gupta, Jen-Chieh Chuang, Bharath K. Mani, Kripa Shankar, Juan A. Rodriguez, Sherri Osborne-Lawrence, Nathan P. Metzger, Jeffrey M. Zigman

Neuropsychopharmacology. 2019 Jun; 44(7): 1319–1327. Published online 2019 Feb 8. doi: 10.1038/s41386-019-0334-7

PMCID:: PMC6785135

Abstract Article PDF–948K

Select item 45005343.

Cardiac Myocyte Alternans in Intact Heart: Influence of Cell-Cell Coupling and β-Adrenergic Stimulation

Karin P. Hammer, Senka Ljubojevic, Crystal M. Ripplinger, Burkert M. Pieske, Donald M. Bers

J Mol Cell Cardiol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: J Mol Cell Cardiol. 2015 Jul; 84: 1–9. Published online 2015 Mar 28. doi: 10.1016/j.yjmcc.2015.03.012

PMCID:: PMC4500534

Abstract Article PDF–1.6M

Select item 38347594.

Chronic activation of the low affinity site of β₁-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodelling

Helen Kiriazis, Niquita Tugiono, Qi Xu, Xiao-Ming Gao, Nicole L Jennings, Ziqui Ming, Yidan Su, Paul Klenowski, Roger J Summers, Alberto Kaumann, Peter Molenaar, Xiao-Jun Du

Br J Pharmacol. 2013 Sep; 170(2): 352–365. Published online 2013 Aug 27. doi: 10.1111/bph.12272

PMCID:: PMC3834759

Abstract Article PDF–1.2M

Select item 32338205.

Temporal analysis of mRNA and miRNA expression in transgenic mice overexpressing Arg- and Gly389 polymorphic variants of the β₁-adrenergic receptor

Karen Dockstader, Karin Nunley, Anis Karimpour-Fard, Allen Medway, Penny Nelson, J. David Port, Stephen B. Liggett, Michael R. Bristow, Carmen C. Sucharov

Physiol Genomics. 2011 Dec; 43(23): 1294–1306. Published online 2011 Sep 27. doi: 10.1152/physiolgenomics.00067.2011

PMCID:: PMC3233820

Abstract Article

Select item 31375566.

Increased tumor necrosis factor-α, cleaved caspase 3 levels and insulin receptor substrate-1 phosphorylation in the β₁-adrenergic receptor knockout mouse

Surekha Rani Panjala, Youde Jiang, Timothy S. Kern, Steven A. Thomas, Jena J. Steinle

Mol Vis. 2011; 17: 1822–1828. Published online 2011 Jul 6.

PMCID:: PMC3137556

Abstract Article PDF–1.2M

Select item 30640037.

Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation

Konstantinos Drosatos, Kalyani G. Bharadwaj, Anastasios Lymperopoulos, Shota Ikeda, Raffay Khan, Yunying Hu, Rajiv Agarwal, Shuiqing Yu, Hongfeng Jiang, Susan F. Steinberg, William S. Blaner, Walter J. Koch, Ira J. Goldberg

Am J Physiol Endocrinol Metab. 2011 Mar; 300(3): E489–E499. Published online 2010 Dec 7. doi: 10.1152/ajpendo.00569.2010

PMCID:: PMC3064003

Abstract Article

Select item 29303818.

β₁-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways

Wei Wang, Hongyu Zhang, Hui Gao, Hajime Kubo, Remus M. Berretta, Xiongwen Chen, Steven R. Houser

Am J Physiol Heart Circ Physiol. 2010 Aug; 299(2): H322–H331. Published online 2010 May 21. doi: 10.1152/ajpheart.00392.2010

PMCID:: PMC2930381

Abstract Article

Select item 22591969.

Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (−)-adrenaline mediated through mouse cardiac β₁-adrenoceptors

A Galindo-Tovar, A J Kaumann

Br J Pharmacol. 2008 Feb; 153(4): 710–720. Published online 2007 Dec 17. doi: 10.1038/sj.bjp.0707631

PMCID:: PMC2259196

Abstract Article PDF–429K

Select item 2205510.

Progressive hypertrophy and heart failure in β₁-adrenergic receptor transgenic mice

Stefan Engelhardt, Lutz Hein, Frank Wiesmann, Martin J. Lohse

Proc Natl Acad Sci U S A. 1999 Jun 8; 96(12): 7059–7064. doi: 10.1073/pnas.96.12.7059

PMCID:: PMC22055

Abstract Article PDF–281K

Select item 1093318111.

Protective effects of Gα_i3 deficiency in a murine heart-failure model of β₁-adrenoceptor overexpression

Tobias Schröper, Dennis Mehrkens, Veronika Leiss, Frederik Tellkamp, Stefan Engelhardt, Stefan Herzig, Lutz Birnbaumer, Bernd Nürnberg, Jan Matthes

Naunyn Schmiedebergs Arch Pharmacol. 2024; 397(4): 2401–2420. Published online 2023 Oct 16. doi: 10.1007/s00210-023-02751-8

PMCID:: PMC10933181

Abstract Article PDF–5.5M

Select item 1021873012.

Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice

Jintao Wang, Jessica Venugopal, Paul Silaghi, Enming J. Su, Chiao Guo, Daniel A. Lawrence, Daniel T. Eitzman

PLoS One. 2023; 18(5): e0285499. Published online 2023 May 26. doi: 10.1371/journal.pone.0285499

PMCID:: PMC10218730

Abstract Article PDF–1.4M

Select item 1010452613.

Mutant β₁-adrenergic receptor improves REM sleep and ameliorates tau accumulation in a mouse model of tauopathy

Qing Dong, Louis J. Ptáček, Ying-Hui Fu

Proc Natl Acad Sci U S A. 2023 Apr 11; 120(15): e2221686120. Published online 2023 Apr 4. doi: 10.1073/pnas.2221686120

PMCID:: PMC10104526

Abstract Article PDF–5.0M

Select item 946258314.

Pharmacological activation of the C5a receptor leads to stimulation of the β-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer’s disease

Eleni Fella, Revekka Papacharalambous, Demos Kynigopoulos, Maria Ioannou, Rita Derua, Christiana Christodoulou, Myrto Stylianou, Christos Karaiskos, Alexia Kagiava, Gerasimou Petroula, Chryso Pierides, Maria Kyriakou, Laura Koumas, Paul Costeas, Elena Panayiotou

Front Immunol. 2022; 13: 947071. Published online 2022 Aug 26. doi: 10.3389/fimmu.2022.947071