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Select item 72906021.

Glial A_2B Adenosine Receptors Modulate Abnormal Tachykininergic Responses and Prevent Enteric Inflammation Associated with High Fat Diet-Induced Obesity

Vanessa D’Antongiovanni, Laura Benvenuti, Matteo Fornai, Carolina Pellegrini, Renè van den Wijngaard, Silvia Cerantola, Maria Cecilia Giron, Valentina Caputi, Rocchina Colucci, Gyorgy Haskó, Zoltán H. Németh, Corrado Blandizzi, Luca Antonioli

Cells. 2020 May; 9(5): 1245. Published online 2020 May 18. doi: 10.3390/cells9051245

PMCID:: PMC7290602

Abstract Article PDF–3.0M

Select item 59922712.

Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension

Tinne C. J. Mertens, Ankit Hanmandlu, Ly Tu, Carole Phan, Scott D. Collum, Ning-Yuan Chen, Tingting Weng, Jonathan Davies, Chen Liu, Holger K. Eltzschig, Soma S. K. Jyothula, Keshava Rajagopal, Yang Xia, Ashrith Guha, Brian A. Bruckner, Michael R. Blackburn, Christophe Guignabert, Harry Karmouty-Quintana

Front Physiol. 2018; 9: 555. Published online 2018 Jun 1. doi: 10.3389/fphys.2018.00555

PMCID:: PMC5992271

Abstract Article PDF–5.4M

Select item 57148403.

Colonic motor dysfunctions in a mouse model of high-fat diet-induced obesity: an involvement of A_2B adenosine receptors

Luca Antonioli, Carolina Pellegrini, Matteo Fornai, Erika Tirotta, Daniela Gentile, Laura Benvenuti, Maria Cecilia Giron, Valentina Caputi, Ilaria Marsilio, Genny Orso, Nunzia Bernardini, Cristina Segnani, Chiara Ippolito, Balázs Csóka, Zoltán H. Németh, György Haskó, Carmelo Scarpignato, Corrado Blandizzi, Rocchina Colucci

Purinergic Signal. 2017 Dec; 13(4): 497–510. Published online 2017 Aug 14. doi: 10.1007/s11302-017-9577-0

PMCID:: PMC5714840

Abstract Article PDF–4.6M

Select item 47639764.

Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension

Harry Karmouty-Quintana, Kemly Philip, Luis F. Acero, Ning-Yuan Chen, Tingting Weng, Jose G. Molina, Fayong Luo, Jonathan Davies, Ngoc-Bao Le, Isabelle Bunge, Kelly A. Volcik, Thanh-Thuy T. Le, Richard A. Johnston, Yang Xia, Holger K. Eltzschig, Michael R. Blackburn

FASEB J. 2015 Jan; 29(1): 50–60. Published online 2014 Oct 15. doi: 10.1096/fj.14-260182

PMCID:: PMC4763976

Abstract Article

Select item 45982745.

Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis

CM Aherne, B Saeedi, CB Collins, JC Masterson, EN McNamee, L Perrenoud, CR Rapp, VF Curtis, A Bayless, A Fletcher, LE Glover, CM Evans, P Jedlicka, GT Furuta, EF de Zoeten, SP Colgan, HK Eltzschig

Mucosal Immunol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Mucosal Immunol. 2015 Nov; 8(6): 1324–1338. Published online 2015 Apr 8. doi: 10.1038/mi.2015.22

Correction in:: Mucosal Immunol. 2015 May; 8(3): 699.

PMCID:: PMC4598274

Abstract Article PDF–979K

Select item 44929706.

An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation

Mingjiazi Chen, Dongchun Liang, Aijun Zuo, Hui Shao, Henry J. Kaplan, Deming Sun

PLoS One. 2015; 10(7): e0132348. Published online 2015 Jul 6. doi: 10.1371/journal.pone.0132348

PMCID:: PMC4492970

Abstract Article PDF–2.2M

Select item 40437707.

The Macrophage A2b Adenosine Receptor Regulates Tissue Insulin Sensitivity

Hillary Johnston-Cox, Anna S. Eisenstein, Milka Koupenova, Shannon Carroll, Katya Ravid

PLoS One. 2014; 9(6): e98775. Published online 2014 Jun 3. doi: 10.1371/journal.pone.0098775

PMCID:: PMC4043770

Abstract Article PDF–1.8M

Select item 39314028.

A_2B Adenosine Receptors Prevent Insulin Resistance by Inhibiting Adipose Tissue Inflammation via Maintaining Alternative Macrophage Activation

Balázs Csóka, Balázs Koscsó, Gábor Törő, Endre Kókai, László Virág, Zoltán H. Németh, Pál Pacher, Péter Bai, György Haskó

Diabetes. 2014 Mar; 63(3): 850–866. Published online 2014 Feb 13. doi: 10.2337/db13-0573

PMCID:: PMC3931402

Abstract Article PDF–2.0M

Select item 36072909.

Distinct Roles for the A_2B Adenosine Receptor in Acute and Chronic Stages of Bleomycin-Induced Lung Injury

Yang Zhou, Daniel J. Schneider, Eva Morschl, Ling Song, Mesias Pedroza, Harry Karmouty-Quintana, Thuy Le, Chun-Xiao Sun, Michael R. Blackburn

J Immunol. Author manuscript; available in PMC 2013 Mar 25.

Published in final edited form as: J Immunol. 2011 Jan 15; 186(2): 1097–1106. Published online 2010 Dec 13. doi: 10.4049/jimmunol.1002907

PMCID:: PMC3607290

Abstract Article PDF–3.9M

Select item 334609610.

A2B Adenosine Receptor Promotes Mesenchymal Stem Cell Differentiation to Osteoblasts and Bone Formation in Vivo

Shannon H. Carroll, Nathan A. Wigner, Nitin Kulkarni, Hillary Johnston-Cox, Louis C. Gerstenfeld, Katya Ravid

J Biol Chem. 2012 May 4; 287(19): 15718–15727. Published online 2012 Mar 8. doi: 10.1074/jbc.M112.344994

PMCID:: PMC3346096

Abstract Article PDF–1.6M

Select item 325465211.

A2BR Adenosine Receptor Modulates Sweet Taste in Circumvallate Taste Buds

Shinji Kataoka, Arian Baquero, Dan Yang, Nicole Shultz, Aurelie Vandenbeuch, Katya Ravid, Sue C. Kinnamon, Thomas E. Finger

PLoS One. 2012; 7(1): e30032. Published online 2012 Jan 10. doi: 10.1371/journal.pone.0030032

PMCID:: PMC3254652

Abstract Article PDF–945K

Select item 313633412.

A_2B adenosine receptor contributes to penile erection via PI3K/AKT signaling cascade-mediated eNOS activation

Jiaming Wen, Almut Grenz, Yujin Zhang, Yingbo Dai, Rodney E. Kellems, Michael R. Blackburn, Holger K. Eltzschig, Yang Xia

FASEB J. 2011 Aug; 25(8): 2823–2830. doi: 10.1096/fj.11-181057

PMCID:: PMC3136334

Abstract Article

Select item 287444213.

Attenuation of Chronic Pulmonary Inflammation in A_2B Adenosine Receptor Knockout Mice

Rinat Zaynagetdinov, Sergey Ryzhov, Anna E. Goldstein, Huiyong Yin, Sergey V. Novitskiy, Kasia Goleniewska, Vasiliy V. Polosukhin, Dawn C. Newcomb, Daphne Mitchell, Eva Morschl, Yang Zhou, Michael R. Blackburn, R. Stokes Peebles, Jr., Italo Biaggioni, Igor Feoktistov

Am J Respir Cell Mol Biol. 2010 May; 42(5): 564–571. Published online 2009 Jun 25. doi: 10.1165/rcmb.2008-0391OC

PMCID:: PMC2874442

Abstract Article PDF–746K

Select item 285878814.

Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury

Ulrich Schingnitz, Katherine Hartman, Christopher F. MacManus, Tobias Eckle, Stephanie Zug, Sean P. Colgan, Holger K. Eltzschig

J Immunol. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: J Immunol. 2010 May 1; 184(9): 5271–5279. Published online 2010 Mar 26. doi: 10.4049/jimmunol.0903035

PMCID:: PMC2858788

Abstract Article PDF–2.8M

Select item 273977615.

Adenosine A_2B receptors are highly expressed on murine type II alveolar epithelial cells

Rebecca E. Cagnina, Susan I. Ramos, Melissa A. Marshall, Guoquan Wang, C. Renea Frazier, Joel Linden

Am J Physiol Lung Cell Mol Physiol. 2009 Sep; 297(3): L467–L474. Published online 2009 Jul 2. doi: 10.1152/ajplung.90553.2008

PMCID:: PMC2739776

Abstract Article

Select item 271777816.

Adenosine 2B receptors (A_2BAR) on enteric neurons regulate murine distal colonic motility

Bindu P. Chandrasekharan, Vasantha L. Kolachala, Guillaume Dalmasso, Didier Merlin, Katya Ravid, Shanthi V. Sitaraman, Shanthi Srinivasan

FASEB J. 2009 Aug; 23(8): 2727–2734. doi: 10.1096/fj.09-129544

PMCID:: PMC2717778

Abstract Article

Select item 263286117.

A2B adenosine receptor gene deletion attenuates murine colitis

Vasantha L Kolachala, Matam Vijay-Kumar, Guilliume Dalmasso, Dan Yang, Joel Linden, Lixin Wang, Andrew Gewirtz, Katya Ravid, Didier Merlin, Shanthi V. Sitaraman

Gastroenterology. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: Gastroenterology. 2008 Sep; 135(3): 861–870. Published online 2008 May 21. doi: 10.1053/j.gastro.2008.05.049

PMCID:: PMC2632861

Abstract Article PDF–4.7M

Select item 258339718.

TNF-alpha upregulates the A_2B adenosine receptor gene: the role of NAD(P)H oxidase 4

Cynthia St. Hilaire, Milka Koupenova, Shannon H. Carroll, Barbara D. Smith, Katya Ravid

Biochem Biophys Res Commun. Author manuscript; available in PMC 2009 Oct 24.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Oct 24; 375(3): 292–296. Published online 2008 Jul 21. doi: 10.1016/j.bbrc.2008.07.059

PMCID:: PMC2583397

Abstract Article PDF–370K

Select item 244008719.

Blockade of adenosine A_2B receptors ameliorates murine colitis

V L Kolachala, B K Ruble, M Vijay-Kumar, L Wang, S Mwangi, H E Figler, R A Figler, S Srinivasan, A T Gewirtz, J Linden, D Merlin, S V Sitaraman

Br J Pharmacol. 2008 Sep; 155(1): 127–137. Published online 2008 Jun 9. doi: 10.1038/bjp.2008.227

PMCID:: PMC2440087

Abstract Article PDF–459K

Select item 148317020.

The A_2B adenosine receptor protects against inflammation and excessive vascular adhesion

Dan Yang, Ying Zhang, Hao G. Nguyen, Milka Koupenova, Anil K. Chauhan, Maria Makitalo, Matthew R. Jones, Cynthia St. Hilaire, David C. Seldin, Paul Toselli, Edward Lamperti, Barbara M. Schreiber, Haralambos Gavras, Denisa D. Wagner, Katya Ravid

J Clin Invest. 2006 Jul 3; 116(7): 1913–1923. Published online 2006 Jul 3. doi: 10.1172/JCI27933