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Select item 69414991.

Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin–Induced Diarrhea

Robert A Fenton, Sathish K Murali, Izumi Kaji, Yasutada Akiba, Jonathan D Kaunitz, Tina B Kristensen, Søren B Poulsen, Jessica A Dominguez Rieg, Timo Rieg

J Infect Dis. 2019 Dec 1; 220(11): 1719–1728. Published online 2019 Jan 8. doi: 10.1093/infdis/jiz013

PMCID:: PMC6941499

Abstract Article PDF–5.4M

Select item 55840492.

The type VI adenylyl cyclase protects cardiomyocytes from β-adrenergic stress by a PKA/STAT3-dependent pathway

Yu-Shuo Wu, Chien-Chang Chen, Chen-Li Chien, Hsing-Lin Lai, Si-Tse Jiang, Yong-Cyuan Chen, Lin-Ping Lai, Wei-Fan Hsiao, Wen-Pin Chen, Yijuang Chern

J Biomed Sci. 2017; 24: 68. Published online 2017 Sep 4. doi: 10.1186/s12929-017-0367-3

PMCID:: PMC5584049

Abstract Article PDF–3.1M

Select item 55402753.

Cardiac-directed expression of a catalytically inactive adenylyl cyclase 6 protects the heart from sustained β-adrenergic stimulation

Mei Hua Gao, N. Chin Lai, Dimosthenis Giamouridis, Young Chul Kim, Tracy Guo, H. Kirk Hammond

PLoS One. 2017; 12(8): e0181282. Published online 2017 Aug 2. doi: 10.1371/journal.pone.0181282

PMCID:: PMC5540275

Abstract Article PDF–3.7M

Select item 53740784.

Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus

Søren Brandt Poulsen, Tina Bøgelund Kristensen, Heddwen L. Brooks, Donald E. Kohan, Timo Rieg, Robert A. Fenton

JCI Insight. 2017 Apr 6; 2(7): e91042. Published online 2017 Apr 6. doi: 10.1172/jci.insight.91042

PMCID:: PMC5374078

Abstract Article PDF–1.8M

Select item 42809735.

The role of adenylyl cyclase isoform 6 in β-adrenoceptor signalling in murine airways

Mark A Birrell, Sara J Bonvini, Michael A Wortley, James Buckley, Liang Yew-Booth, Sarah A Maher, Nicole Dale, Eric D Dubuis, Maria G Belvisi

Br J Pharmacol. 2015 Jan; 172(1): 131–141. Published online 2014 Nov 24. doi: 10.1111/bph.12905

PMCID:: PMC4280973

Abstract Article PDF–1.1M

Select item 39878126.

Adenylyl Cyclase 6 Deletion Increases Mortality During Sustained β-Adrenergic Receptor Stimulation

Tong Tang, N. Chin Lai, Adam T. Wright, Mei Hua Gao, Paul Lee, Tracy Guo, Ruoying Tang, Andrew D. McCulloch, H. Kirk Hammond

J Mol Cell Cardiol. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: J Mol Cell Cardiol. 2013 Jul; 60: 60–67. Published online 2013 Apr 12. doi: 10.1016/j.yjmcc.2013.04.005

PMCID:: PMC3987812

Abstract Article PDF–1.1M

Select item 39296767.

Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo

Kristen L. Lee, David A. Hoey, Milos Spasic, Tong Tang, H. Kirk Hammond, Christopher R. Jacobs

FASEB J. 2014 Mar; 28(3): 1157–1165. doi: 10.1096/fj.13-240432

PMCID:: PMC3929676

Abstract Article

Select item 37524518.

Adenylyl cyclase 6 mediates the action of cyclic AMP-dependent secretagogues in mouse pancreatic exocrine cells via protein kinase A pathway activation

Maria E Sabbatini, Louis D’Alecy, Stephen I Lentz, Tong Tang, John A Williams

J Physiol. 2013 Aug 1; 591(Pt 15): 3693–3707. Published online 2013 Jun 10. doi: 10.1113/jphysiol.2012.249698

PMCID:: PMC3752451

Abstract Article PDF–1.1M

Select item 35327159.

Adenylyl Cyclase 6 Enhances NKCC2 Expression and Mediates Vasopressin-Induced Phosphorylation of NKCC2 and NCC

Timo Rieg, Tong Tang, Shinichi Uchida, H. Kirk Hammond, Robert A. Fenton, Volker Vallon

Am J Pathol. 2013 Jan; 182(1): 96–106. doi: 10.1016/j.ajpath.2012.09.014

PMCID:: PMC3532715

Abstract Article PDF–1.5M

Select item 325134310.

Collecting duct-specific knockout of adenylyl cyclase type VI causes a urinary concentration defect in mice

Karl P. Roos, Kevin A. Strait, Kalani L. Raphael, Mitsi A. Blount, Donald E. Kohan

Am J Physiol Renal Physiol. 2012 Jan 1; 302(1): F78–F84. Published online 2011 Sep 21. doi: 10.1152/ajprenal.00397.2011

PMCID:: PMC3251343

Abstract Article

Select item 321930311.

Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart

Yasuo Sugano, N. Chin Lai, Mei Hua Gao, Amy L. Firth, Jason X.-J. Yuan, Wilbur Y.W. Lew, H. Kirk Hammond

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Nov 17.

Published in final edited form as: Biochem Biophys Res Commun. 2011 Feb 18; 405(3): 349–355. Published online 2010 Dec 30. doi: 10.1016/j.bbrc.2010.12.113

PMCID:: PMC3219303

Abstract Article PDF–561K

Select item 308169412.

Adenylyl Cyclase 6 Deletion Reduces Left Ventricular Hypertrophy, Dilation, Dysfunction, and Fibrosis in Pressure-Overloaded Female Mice

Tong Tang, N. Chin Lai, H. Kirk Hammond, David M. Roth, Yuan Yang, Tracy Guo, Mei Hua Gao

J Am Coll Cardiol. Author manuscript; available in PMC 2011 Apr 25.

Published in final edited form as: J Am Coll Cardiol. 2010 Apr 6; 55(14): 1476–1486. doi: 10.1016/j.jacc.2009.11.066

PMCID:: PMC3081694

Abstract Article PDF–1.8M

Select item 301401913.

Adenylate Cyclase 6 Determines cAMP Formation and Aquaporin-2 Phosphorylation and Trafficking in Inner Medulla

Timo Rieg, Tong Tang, Fiona Murray, Jana Schroth, Paul A. Insel, Robert A. Fenton, H. Kirk Hammond, Volker Vallon

J Am Soc Nephrol. 2010 Dec; 21(12): 2059–2068. doi: 10.1681/ASN.2010040409

PMCID:: PMC3014019

Abstract Article

Select item 294447514.

Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload

Aziz Guellich, Shumin Gao, Chull Hong, Lin Yan, Thomas E. Wagner, Sunil K. Dhar, Bijan Ghaleh, Luc Hittinger, Kosaku Iwatsubo, Yoshihiro Ishikawa, Stephen F. Vatner, Dorothy E. Vatner

Am J Physiol Heart Circ Physiol. 2010 Sep; 299(3): H707–H712. Published online 2010 Jun 18. doi: 10.1152/ajpheart.00148.2010

PMCID:: PMC2944475

Abstract Article

Select item 290928215.

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells

Ronald Y. Kwon, Sara Temiyasathit, Padmaja Tummala, Clarence C. Quah, Christopher R. Jacobs

FASEB J. 2010 Aug; 24(8): 2859–2868. doi: 10.1096/fj.09-148007

PMCID:: PMC2909282

Abstract Article

Select item 288661616.

Fibroblast-specific expression of AC6 enhances β-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis

Xiaoqiu Liu, Fengying Li, Shu Qiang Sun, Muthusamy Thangavel, Joseph Kaminsky, Louisa Balazs, Rennolds S. Ostrom

Am J Physiol Lung Cell Mol Physiol. 2010 Jun; 298(6): L819–L829. Published online 2010 Mar 26. doi: 10.1152/ajplung.00429.2009

PMCID:: PMC2886616

Abstract Article

Select item 692019417.

Purβ promotes hepatic glucose production by increasing Adcy6 transcription

Linna Jia, Yunfeng Jiang, Xinzhi Li, Zheng Chen

Mol Metab. 2020 Jan; 31: 85–97. Published online 2019 Nov 16. doi: 10.1016/j.molmet.2019.11.008

PMCID:: PMC6920194

Abstract Article PDF–2.9M

Select item 666867918.

Adenylyl cyclase 5–generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

Arsalan U. Syed, Gopireddy R. Reddy, Debapriya Ghosh, Maria Paz Prada, Matthew A. Nystoriak, Stefano Morotti, Eleonora Grandi, Padmini Sirish, Nipavan Chiamvimonvat, Johannes W. Hell, Luis F. Santana, Yang K. Xiang, Madeline Nieves-Cintrón, Manuel F. Navedo

J Clin Invest. 2019 Aug 1; 129(8): 3140–3152. Published online 2019 Jul 2. doi: 10.1172/JCI124705