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Items: 1 to 20 of 35

1.
Nkx2–5 Regulates the Proliferation and Migration of H9c2 Cells
Hongshu Wang, Yong Liu, Shen Han, Yunfeng Zi, Yayong Zhang, Ruize Kong, Zu Liu, Zhibin Cai, Chongbin Zhong, Wei Liu, Lifeng Li, Lihong Jiang
Med Sci Monit. 2020; 26: e925388-1–e925388-16. Prepublished online 2020 Aug 5. Published online 2020 Aug 11. doi: 10.12659/MSM.925388
PMCID:
PMC7441744
AbstractArticlePDF–2.4M
2.
Role of Nkx2.5 in H2O2-induced Nsd1 suppression
Xiaoyan Liang, Guoming Chu, Leitong Wang, Guangrui Lai, Yanyan Zhao
Cell Stress Chaperones. 2019 Jul; 24(4): 697–707. Published online 2019 May 18. doi: 10.1007/s12192-019-00995-z
PMCID:
PMC6629736
AbstractArticlePDF–1.6M
3.
Nkx2.5/Csx Represses Myofibroblast Differentiation
Biao Hu, Yue Ming Wu, Zhe Wu, Sem H. Phan
Am J Respir Cell Mol Biol. 2010 Feb; 42(2): 218–226. Published online 2009 Apr 24. doi: 10.1165/rcmb.2008-0404OC
PMCID:
PMC2822983
AbstractArticlePDF–824K
4.
Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2‐5 Mutation and a Review of the Literature
Sabrina Gade Ellesøe, Morten Munk Johansen, Jesper Vandborg Bjerre, Vibeke Elisabeth Hjortdal, Søren Brunak, Lars Allan Larsen
Congenit Heart Dis. 2016 May-Jun; 11(3): 283–290. Published online 2015 Dec 18. doi: 10.1111/chd.12317
PMCID:
PMC5019245
AbstractArticlePDF–196K
5.
NKX2-5 Mutations in an Inbred Consanguineous Population: Genetic and Phenotypic Diversity
Ossama K. Abou Hassan, Akl C. Fahed, Manal Batrawi, Mariam Arabi, Marwan M. Refaat, Steven R. DePalma, J. G. Seidman, Christine E. Seidman, Fadi F. Bitar, Georges M. Nemer
Sci Rep. 2015; 5: 8848. Published online 2015 Mar 6. doi: 10.1038/srep08848
PMCID:
PMC4351524
AbstractArticlePDF–647K
6.
The Ambiguous Role of NKX2-5 Mutations in Thyroid Dysgenesis
Klaartje van Engelen, Mathilda T. M. Mommersteeg, Marieke J. H. Baars, Jan Lam, Aho Ilgun, A. S. Paul van Trotsenburg, Anne M. J. B. Smets, Vincent M. Christoffels, Barbara J. M. Mulder, Alex V. Postma
PLoS One. 2012; 7(12): e52685. Published online 2012 Dec 28. doi: 10.1371/journal.pone.0052685
PMCID:
PMC3532205
AbstractArticlePDF–263K
7.
Crystal Structure of the Human NKX2.5 Homeodomain in Complex with DNA Target
Lagnajeet Pradhan, Caroli Genis, Peyton Scone, Ellen O. Weinberg, Hideko Kasahara, Hyun-Joo Nam
Biochemistry. Author manuscript; available in PMC 2012 Sep 21.
Published in final edited form as: Biochemistry. 2012 Aug 14; 51(32): 6312–6319. Published online 2012 Aug 3. doi: 10.1021/bi300849c
PMCID:
PMC3448007
AbstractArticlePDF–1.9M
8.
Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes
Sangeetha Chandrasekaran, Richard E. Peterson, Santhosh K. Mani, Benjamin Addy, Avery L. Buchholz, Lin Xu, Thirumagal Thiyagarajan, Harinath Kasiganesan, Christine B. Kern, Donald R. Menick
FASEB J. 2009 Nov; 23(11): 3851–3864. doi: 10.1096/fj.09-132415
PMCID:
PMC2775004
AbstractArticle
9.
Slow progressive conduction and contraction defects in loss of Nkx2–5 mice after cardiomyocyte terminal differentiation
Morihiko Takeda, Laura E. Briggs, Hiroko Wakimoto, Melissa H. Marks, Sonisha A. Warren, Jonathan T. Lu, Ellen O. Weinberg, Keith D. Robertson, Kenneth R. Chien, Hideko Kasahara
Lab Invest. Author manuscript; available in PMC 2010 Mar 1.
Published in final edited form as: Lab Invest. 2009 Sep; 89(9): 983–993. Published online 2009 Jun 22. doi: 10.1038/labinvest.2009.59
PMCID:
PMC2733927
AbstractArticlePDF–1.8M
10.
Somatic NKX2-5 mutations as a novel mechanism of disease in complex congenital heart disease
S Reamon-Buettner, J Borlak
J Med Genet. 2004 Sep; 41(9): 684–690. doi: 10.1136/jmg.2003.017483
PMCID:
PMC1735891
SummaryPDF–198K
11.
Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways
D. Woodrow Benson, G. Michael Silberbach, Ann Kavanaugh-McHugh, Carol Cottrill, Yizhong Zhang, Steve Riggs, Octavia Smalls, Mark C. Johnson, Michael S. Watson, J.G. Seidman, Christine E. Seidman, John Plowden, John D. Kugler
J Clin Invest. 1999 Dec 1; 104(11): 1567–1573. doi: 10.1172/JCI8154
PMCID:
PMC409866
AbstractArticlePDF–273K
12.
Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein
Hideko Kasahara, Hiroko Wakimoto, Margaret Liu, Colin T. Maguire, Kimber L. Converso, Tetsuo Shioi, Weei-Yuarn Huang, Warren J. Manning, David Paul, Joel Lawitts, Charles I. Berul, Seigo Izumo
J Clin Invest. 2001 Jul 15; 108(2): 189–201. doi: 10.1172/JCI12694
PMCID:
PMC203028
AbstractArticlePDF–5.7M
13.
A mouse model of human congenital heart disease: high incidence of diverse cardiac anomalies and ventricular noncompaction produced by heterozygous Nkx2-5 homeodomain missense mutation
Hassan Ashraf, Lagnajeet Pradhan, Eileen I. Chang, Ryota Terada, Nicole J. Ryan, Laura E. Briggs, Rajib Chowdhury, Miguel A. Zárate, Yukiko Sugi, Hyun-Joo Nam, D. Woodrow Benson, Robert H. Anderson, Hideko Kasahara
Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Aug 1.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Aug; 7(4): 423–433. Published online 2014 Jul 15. doi: 10.1161/CIRCGENETICS.113.000281
PMCID:
PMC4140955
AbstractArticlePDF–3.3M
14.
Perinatal Loss of Nkx2-5 Results in Rapid Conduction and Contraction Defects
Laura E. Briggs, Morihiko Takeda, Adolfo E. Cuadra, Hiroko Wakimoto, Melissa H. Marks, Alexandra J. Walker, Tsugio Seki, Suk P. Oh, Jonathan T. Lu, Colin Sumners, Mohan K. Raizada, Nobuo Horikoshi, Ellen O. Weinberg, Kenji Yasui, Yasuhiro Ikeda, Kenneth R. Chien, Hideko Kasahara
Circ Res. Author manuscript; available in PMC 2008 Nov 28.
Published in final edited form as: Circ Res. 2008 Sep 12; 103(6): 580–590. Published online 2008 Aug 8. doi: 10.1161/CIRCRESAHA.108.171835
PMCID:
PMC2590500
AbstractArticlePDF–2.1M
15.
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors.
D Durocher, F Charron, R Warren, R J Schwartz, M Nemer
EMBO J. 1997 Sep 15; 16(18): 5687–5696. doi: 10.1093/emboj/16.18.5687
PMCID:
PMC1170200
SummaryPDF–437K
16.
Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system
Patrick Y. Jay, Brett S. Harris, Colin T. Maguire, Antje Buerger, Hiroko Wakimoto, Makoto Tanaka, Sabina Kupershmidt, Dan M. Roden, Thomas M. Schultheiss, Terrence X. O’Brien, Robert G. Gourdie, Charles I. Berul, Seigo Izumo
J Clin Invest. 2004 Apr 15; 113(8): 1130–1137. doi: 10.1172/JCI19846
PMCID:
PMC385399
AbstractArticlePDF–2.3M
17.
Myocardin Expression Is Regulated by Nkx2.5, and Its Function Is Required for Cardiomyogenesis
Tomomi Ueyama, Hideko Kasahara, Takahiro Ishiwata, Qing Nie, Seigo Izumo
Mol Cell Biol. 2003 Dec; 23(24): 9222–9232. doi: 10.1128/MCB.23.24.9222-9232.2003
PMCID:
PMC309615
AbstractArticlePDF–747K
18.
Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block
Ninda Syam, Stéphanie Chatel, Lijo Cherian Ozhathil, Valentin Sottas, Jean‐Sébastien Rougier, Alban Baruteau, Estelle Baron, Mohamed‐Yassine Amarouch, Xavier Daumy, Vincent Probst, Jean‐Jacques Schott, Hugues Abriel
J Am Heart Assoc. 2016 May; 5(5): e001625. Published online 2016 May 20. doi: 10.1161/JAHA.114.001625
PMCID:
PMC4889160
AbstractArticlePDF–1.9M
19.
Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription.
C Y Chen, R J Schwartz
Mol Cell Biol. 1996 Nov; 16(11): 6372–6384. doi: 10.1128/mcb.16.11.6372
PMCID:
PMC231639
SummaryPDF–1.8M
20.
Identification of the In Vivo Casein Kinase II Phosphorylation Site within the Homeodomain of the Cardiac Tisue-Specifying Homeobox Gene Product Csx/Nkx2.5
Hideko Kasahara, Seigo Izumo
Mol Cell Biol. 1999 Jan; 19(1): 526–536. doi: 10.1128/mcb.19.1.526
PMCID:
PMC83910
AbstractArticlePDF–1.5M

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