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Select item 108197631.

Reconstitution of the phosphodiesterase 6 maturation process important for photoreceptor cell function

Sneha Singh, Dhiraj Srivastava, Kimberly Boyd, Nikolai O. Artemyev

J Biol Chem. 2024 Jan; 300(1): 105576. Published online 2023 Dec 16. doi: 10.1016/j.jbc.2023.105576

PMCID:: PMC10819763

Abstract Article PDF–1.0M

Select item 106765652.

An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas

Vismaya S. Bachu, Sangeetha Kandoi, Ko Uoon Park, Michael L. Kaufman, Michael Schwanke, Deepak A. Lamba, Joseph A. Brzezinski, IV

Dev Biol. Author manuscript; available in PMC 2023 Nov 26.

Published in final edited form as: Dev Biol. 2022 Aug; 488: 131–150. Published online 2022 May 26. doi: 10.1016/j.ydbio.2022.05.012

PMCID:: PMC10676565

Abstract Article PDF–2.9M

Select item 74428673.

Validating Fluorescent Chrnb4.EGFP Mouse Models for the Study of Cone Photoreceptor Degeneration

Alicia A. Brunet, Paula I. Fuller-Carter, Annie L. Miller, Valentina Voigt, Sophia Vasiliou, Rabab Rashwan, David M. Hunt, Livia S. Carvalho

Transl Vis Sci Technol. 2020 Aug; 9(9): 28. Published online 2020 Aug 18. doi: 10.1167/tvst.9.9.28

PMCID:: PMC7442867

Abstract Article PDF–3.6M

Select item 69811884.

Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors restores vision in mice

Koji M. Nishiguchi, Kosuke Fujita, Fuyuki Miya, Shota Katayama, Toru Nakazawa

Nat Commun. 2020; 11: 482. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14181-3

PMCID:: PMC6981188

Abstract Article PDF–1.5M

Select item 61710505.

Retained Plasticity and Substantial Recovery of Rod-Mediated Visual Acuity at the Visual Cortex in Blind Adult Mice with Retinal Dystrophy

Koji M. Nishiguchi, Kosuke Fujita, Naoyuki Tokashiki, Hiroshi Komamura, Sayaka Takemoto-Kimura, Hiroyuki Okuno, Haruhiko Bito, Toru Nakazawa

Mol Ther. 2018 Oct 3; 26(10): 2397–2406. Published online 2018 Jul 17. doi: 10.1016/j.ymthe.2018.07.012

PMCID:: PMC6171050

Abstract Article PDF–2.1M

Select item 60464376.

Cone Phosphodiesterase-6γ’ Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits

Wen-Tao Deng, Saravanan Kolandaivelu, Astra Dinculescu, Jie Li, Ping Zhu, Vince A. Chiodo, Visvanathan Ramamurthy, William W. Hauswirth

Front Mol Neurosci. 2018; 11: 233. Published online 2018 Jul 9. doi: 10.3389/fnmol.2018.00233

PMCID:: PMC6046437

Abstract Article PDF–2.5M

Select item 27807907.

A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene

Bo Chang, Tanja Grau, Susann Dangel, Ron Hurd, Bernhard Jurklies, E. Cumhur Sener, Sten Andreasson, Helene Dollfus, Britta Baumann, Sylvia Bolz, Nikolai Artemyev, Susanne Kohl, John Heckenlively, Bernd Wissinger

Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46): 19581–19586. Published online 2009 Nov 3. doi: 10.1073/pnas.0907720106

PMCID:: PMC2780790

Abstract Article PDF–1.7M

Select item 49655768.

Aryl Hydrocarbon Receptor-interacting Protein-like 1 Is an Obligate Chaperone of Phosphodiesterase 6 and Is Assisted by the γ-Subunit of Its Client

Kota N. Gopalakrishna, Kimberly Boyd, Ravi P. Yadav, Nikolai O. Artemyev

J Biol Chem. 2016 Jul 29; 291(31): 16282–16291. Published online 2016 Jun 7. doi: 10.1074/jbc.M116.737593

PMCID:: PMC4965576

Abstract Article PDF–1.8M

Select item 69743539.

Rod nuclear architecture determines contrast transmission of the retina and behavioral sensitivity in mice

Kaushikaram Subramanian, Martin Weigert, Oliver Borsch, Heike Petzold, Alfonso Garcia-Ulloa, Eugene W Myers, Marius Ader, Irina Solovei, Moritz Kreysing

eLife. 2019; 8: e49542. Published online 2019 Dec 11. doi: 10.7554/eLife.49542

PMCID:: PMC6974353

Abstract Article PDF–4.4M

Select item 510211410.

Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration

Fan Yang, Hongwei Ma, Joshua Belcher, Michael R. Butler, T. Michael Redmond, Sanford L. Boye, William W. Hauswirth, Xi-Qin Ding

FASEB J. 2016 Dec; 30(12): 4313–4325. Published online 2016 Sep 13. doi: 10.1096/fj.201600715R

PMCID:: PMC5102114

Abstract Article

Select item 433853111.

Retinal output changes qualitatively with every change in ambient illuminance

Alexandra Tikidji-Hamburyan, Katja Reinhard, Hartwig Seitter, Anahit Hovhannisyan, Christopher A. Procyk, Annette E. Allen, Martin Schenk, Robert J. Lucas, Thomas A. Münch

Nat Neurosci. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Nat Neurosci. 2015 Jan; 18(1): 66–74. Published online 2014 Dec 8. doi: 10.1038/nn.3891

PMCID:: PMC4338531

Abstract Article PDF–2.5M

Select item 394822812.

Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration

Hongwei Ma, Arjun Thapa, Lynsie Morris, T. Michael Redmond, Wolfgang Baehr, Xi-Qin Ding

Proc Natl Acad Sci U S A. 2014 Mar 4; 111(9): 3602–3607. Published online 2014 Feb 18. doi: 10.1073/pnas.1317041111

PMCID:: PMC3948228

Abstract Article PDF–2.3M

Select item 319086613.

Rod Phosphodiesterase-6 (PDE6) Catalytic Subunits Restore Cone Function in a Mouse Model Lacking Cone PDE6 Catalytic Subunit

Saravanan Kolandaivelu, Bo Chang, Visvanathan Ramamurthy

J Biol Chem. 2011 Sep 23; 286(38): 33252–33259. Published online 2011 Jul 28. doi: 10.1074/jbc.M111.259101

PMCID:: PMC3190866

Abstract Article PDF–1.6M

Select item 570372914.

Rods progressively escape saturation to drive visual responses in daylight conditions

Alexandra Tikidji-Hamburyan, Katja Reinhard, Riccardo Storchi, Johannes Dietter, Hartwig Seitter, Katherine E. Davis, Saad Idrees, Marion Mutter, Lauren Walmsley, Robert A. Bedford, Marius Ueffing, Petri Ala-Laurila, Timothy M. Brown, Robert J. Lucas, Thomas A. Münch

Nat Commun. 2017; 8: 1813. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01816-6

PMCID:: PMC5703729

Abstract Article PDF–12M

Select item 550370315.

Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration

Hongwei Ma, Fan Yang, Michael R. Butler, Joshua Belcher, T. Michael Redmond, Andrew T. Placzek, Thomas S. Scanlan, Xi-Qin Ding

FASEB J. 2017 Aug; 31(8): 3425–3438. Published online 2017 Apr 20. doi: 10.1096/fj.201601166RR

PMCID:: PMC5503703

Abstract Article

Select item 342718616.

Rod-Driven OFF Pathway Responses in the Distal Retina: Dark-Adapted Flicker Electroretinogram in Mouse

Bo Lei

PLoS One. 2012; 7(8): e43856. Published online 2012 Aug 24. doi: 10.1371/journal.pone.0043856

PMCID:: PMC3427186

Abstract Article PDF–1.5M

Select item 423098317.

Identification of a Common Non-Apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration

Blanca Arango-Gonzalez, Dragana Trifunović, Ayse Sahaboglu, Katharina Kranz, Stylianos Michalakis, Pietro Farinelli, Susanne Koch, Fred Koch, Sandra Cottet, Ulrike Janssen-Bienhold, Karin Dedek, Martin Biel, Eberhart Zrenner, Thomas Euler, Per Ekström, Marius Ueffing, François Paquet-Durand

PLoS One. 2014; 9(11): e112142. Published online 2014 Nov 13. doi: 10.1371/journal.pone.0112142