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Items: 1 to 20 of 52

1.
PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway
Xuming Tang, Tingting Cao, Yun Zhu, Liyi Zhang, Jinna Chen, Tengfei Liu, Xiaoyan Ming, Shuo Fang, Yun-fei Yuan, Lingxi Jiang, Jian-Dong Huang, Xin-Yuan Guan
Cell Death Dis. 2020 Jul; 11(7): 510. Published online 2020 Jul 2. doi: 10.1038/s41419-020-2700-0
PMCID:
PMC7343807
AbstractArticlePDF–5.6M
2.
Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression
Pia Kronschnabl, Arnold Grünweller, Roland K. Hartmann, Achim Aigner, Ulrike Weirauch
Int J Oncol. 2020 Feb; 56(2): 448–459. Published online 2019 Dec 10. doi: 10.3892/ijo.2019.4936
PMCID:
PMC6959465
AbstractArticlePDF–1.4M
3.
Role of PIM2 in allergic asthma
Wei Du, Tiantian Chen, Yingmeng Ni, Xiaoxia Hou, Youchao Yu, Qi Zhou, Fang Wu, Wei Tang, Guochao Shi
Mol Med Rep. 2017 Nov; 16(5): 7504–7512. Published online 2017 Sep 18. doi: 10.3892/mmr.2017.7499
PMCID:
PMC5865883
AbstractArticlePDF–1.3M
4.
Pim2 is important for regulating DNA damage response in multiple myeloma cells
J Ramachandran, L Santo, K T Siu, C Panaroni, N Raje
Blood Cancer J. 2016 Aug; 6(8): e462. Published online 2016 Aug 26. doi: 10.1038/bcj.2016.73
PMCID:
PMC5022183
AbstractArticlePDF–1.2M
5.
Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas
S. Kreuz, K. B. Holmes, R. M. Tooze, P. F. Lefevre
Mol Cancer. 2015; 14: 205. Published online 2015 Dec 8. doi: 10.1186/s12943-015-0477-z
PMCID:
PMC4672512
AbstractArticlePDF–2.6M
6.
Control of Pim2 kinase stability and expression in transformed human haematopoietic cells
Kévin Adam, Mireille Lambert, Elsa Lestang, Gabriel Champenois, Isabelle Dusanter-Fourt, Jérôme Tamburini, Didier Bouscary, Catherine Lacombe, Yael Zermati, Patrick Mayeux
Biosci Rep. 2015 Dec; 35(6): e00274. Prepublished online 2015 Oct 23. Published online 2015 Dec 8. doi: 10.1042/BSR20150217
PMCID:
PMC4672348
AbstractArticlePDF–1.1M
7.
Pim-2 Modulates Aerobic Glycolysis and Energy Production during the Development of Colorectal Tumors
Xue-hui Zhang, Hong-liang Yu, Fu-jing Wang, Yong-long Han, Wei-liang Yang
Int J Med Sci. 2015; 12(6): 487–493. Published online 2015 Jun 8. doi: 10.7150/ijms.10982
PMCID:
PMC4466513
AbstractArticlePDF–494K
8.
Pim-2/mTORC1 Pathway Shapes Inflammatory Capacity in Rheumatoid Arthritis Synovial Cells Exposed to Lipid Peroxidations
Geng Yin, Yan Li, Min Yang, Xiao-min Cen, Qi-bing Xie
Biomed Res Int. 2015; 2015: 240210. Published online 2015 May 4. doi: 10.1155/2015/240210
PMCID:
PMC4434176
AbstractArticlePDF–2.0M
9.
Activation of Cell Cycle Arrest and Apoptosis by the Proto-Oncogene Pim-2
Daphna Levy, Ateret Davidovich, Shahar Zirkin, Yulia Frug, Amos M. Cohen, Sara Shalom, Jeremy Don
PLoS One. 2012; 7(4): e34736. Published online 2012 Apr 10. doi: 10.1371/journal.pone.0034736
PMCID:
PMC3323563
AbstractArticlePDF–821K
10.
Ectopic Over-expression of Oncogene Pim-2 Induce Malignant Transformation of Nontumorous Human Liver Cell Line L02
Ke Ren, Wentao Duan, Yujun Shi, Bo Li, Zuojin Liu, Jiangping Gong
J Korean Med Sci. 2010 Jul; 25(7): 1017–1023. Published online 2010 Jun 17. doi: 10.3346/jkms.2010.25.7.1017
PMCID:
PMC2890877
AbstractArticlePDF–1.5M
11.
Pim-2 phosphorylation of p21Cip1/WAF1 enhances its stability and inhibits cell proliferation in HCT116 cells
Zeping Wang, Yandong Zhang, Juan Jenny Gu, Christine Davitt, Raymond Reeves, Nancy S. Magnuson
Int J Biochem Cell Biol. Author manuscript; available in PMC 2011 Jun 1.
Published in final edited form as: Int J Biochem Cell Biol. 2010 Jun; 42(6): 1030–1038. Published online 2010 Mar 20. doi: 10.1016/j.biocel.2010.03.012
PMCID:
PMC2862799
AbstractArticlePDF–3.8M
12.
Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor
Alex N. Bullock, Santina Russo, Ann Amos, Nicholas Pagano, Howard Bregman, Judit É. Debreczeni, Wen Hwa Lee, Frank von Delft, Eric Meggers, Stefan Knapp
PLoS One. 2009; 4(10): e7112. Published online 2009 Oct 20. doi: 10.1371/journal.pone.0007112
PMCID:
PMC2743286
AbstractArticlePDF–732K
13.
Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer
Chao Lu, Pengyun Qiao, Yonghong Sun, Chune Ren, Zhenhai Yu
Clin Transl Med. 2021 Apr; 11(4): e400. Published online 2021 May 1. doi: 10.1002/ctm2.400
PMCID:
PMC8087946
AbstractArticlePDF–9.7M
14.
PIM2-mediated phosphorylation of hexokinase 2 is critical for tumor growth and paclitaxel resistance in breast cancer
Tingting Yang, Chune Ren, Pengyun Qiao, Xue Han, Li Wang, Shijun Lv, Yonghong Sun, Zhijun Liu, Yu Du, Zhenhai Yu
Oncogene. 2018; 37(45): 5997–6009. Published online 2018 Jul 9. doi: 10.1038/s41388-018-0386-x
Correction in:
Oncogene. 2020; 39(3): 720–721.
PMCID:
PMC6224402
AbstractArticlePDF–3.6M
15.
Microenvironment‐induced PIM kinases promote CXCR4‐triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration
Emilia Białopiotrowicz, Patryk Górniak, Monika Noyszewska‐Kania, Bartosz Puła, Hanna Makuch‐Łasica, Grażyna Nowak, Aleksandra Bluszcz, Maciej Szydłowski, Ewa Jabłonska, Karolina Piechna, Tomasz Sewastianik, Anna Polak, Ewa Lech‐Marańda, Bożena K. Budziszewska, Maja Wasylecka‐Juszczyńska, Katarzyna Borg, Krzysztof Warzocha, Wojciech Czardybon, Michał Gałęzowski, Renata Windak, Krzysztof Brzózka, Przemysław Juszczyński
J Cell Mol Med. 2018 Jul; 22(7): 3548–3559. Published online 2018 Apr 17. doi: 10.1111/jcmm.13632
PMCID:
PMC6010703
AbstractArticlePDF–1.4M
16.
PIM2 interacts with tristetraprolin and promotes breast cancer tumorigenesis
Chune Ren, Tingting Yang, Pengyun Qiao, Li Wang, Xue Han, Shijun Lv, Yonghong Sun, Zhijun Liu, Yu Du, Zhenhai Yu
Mol Oncol. 2018 May; 12(5): 690–704. Published online 2018 Apr 14. doi: 10.1002/1878-0261.12192
PMCID:
PMC5928357
AbstractArticlePDF–1.3M
17.
The role of PIM1/PIM2 kinases in tumors of the male reproductive system
Manuel Pedro Jiménez-García, Antonio Lucena-Cacace, María José Robles-Frías, Maja Narlik-Grassow, Carmen Blanco-Aparicio, Amancio Carnero
Sci Rep. 2016; 6: 38079. Published online 2016 Nov 30. doi: 10.1038/srep38079
PMCID:
PMC5128923
AbstractArticlePDF–3.6M
18.
Persistent activation of STAT3 by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer
Nizam Uddin, Rae-Kwon Kim, Ki-Chun Yoo, Young-Heon Kim, Yan-Hong Cui, In-Gyu Kim, Yongjoon Suh, Su-Jae Lee
Cancer Sci. 2015 Jun; 106(6): 718–725. Published online 2015 May 8. doi: 10.1111/cas.12668
PMCID:
PMC4471798
AbstractArticlePDF–2.2M
19.
Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation
Jing Lu, Tatiana Zavorotinskaya, Yumin Dai, Xiao-Hong Niu, Joseph Castillo, Janet Sim, Jianjun Yu, Yingyun Wang, John L. Langowski, Jocelyn Holash, Kevin Shannon, Pablo D. Garcia
Blood. 2013 Aug 29; 122(9): 1610–1620. Prepublished online 2013 Jul 1. doi: 10.1182/blood-2013-01-481457
PMCID:
PMC3953014
AbstractArticle
20.
A Regulatory Feedback Loop between HIF-1α and PIM2 in HepG2 Cells
Zhenhai Yu, Xiaoping Zhao, Yingying Ge, Teng Zhang, Liangqian Huang, Xiang Zhou, Lei Xie, Jianjun Liu, Gang Huang
PLoS One. 2014; 9(2): e88301. Published online 2014 Feb 5. doi: 10.1371/journal.pone.0088301
PMCID:
PMC3914973
AbstractArticlePDF–1.2M

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