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Items: 1 to 20 of 80

1.
Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo
Xu Sun, Ce Shi, Jin Dai, Mei-Qing Zhang, Dong-Sheng Pei, Lei Yang
Cell Death Dis. 2024 May; 15(5): 346. Published online 2024 May 20. doi: 10.1038/s41419-024-06722-6
PMCID:
PMC11106333
AbstractArticlePDF–6.2M
2.
YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress
T Kelly Rainbolt, Jaclyn M Saunders, R Luke Wiseman
EMBO Rep. 2015 Jan; 16(1): 97–106. Published online 2014 Nov 28. doi: 10.15252/embr.201438976
PMCID:
PMC4304733
AbstractArticlePDF–1.3M
3.
Stress-Regulated Translational Attenuation Adapts Mitochondrial Protein Import Through Tim17A Degradation
T. Kelly Rainbolt, Neli Atanassova, Joseph C. Genereux, R. Luke Wiseman
Cell Metab. Author manuscript; available in PMC 2014 Dec 3.
Published in final edited form as: Cell Metab. 2013 Dec 3; 18(6): 908–919. doi: 10.1016/j.cmet.2013.11.006
PMCID:
PMC3904643
AbstractArticlePDF–4.6M
4.
The mitochondrial protein YME1 Like 1 is important for non-small cell lung cancer cell growth
Yingchen Xia, Chunyan He, Zhi Hu, Zhichao Wu, Yin Hui, Yuan-yuan Liu, Chuanyong Mu, Jianhua Zha
Int J Biol Sci. 2023; 19(6): 1778–1790. Published online 2023 Mar 21. doi: 10.7150/ijbs.82217
PMCID:
PMC10092760
AbstractArticlePDF–9.2M
5.
Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion
Ruohan Wang, Prashant Mishra, Spiros D. Garbis, Annie Moradian, Michael J. Sweredoski, David C. Chan
Mol Biol Cell. 2021 Jan 15; 32(2): 157–168. doi: 10.1091/mbc.E20-09-0605
PMCID:
PMC8120690
AbstractArticlePDF–2.8M
6.
Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma
Vinodh Srinivasainagendra, Michael W. Sandel, Bhupendra Singh, Aishwarya Sundaresan, Ved P. Mooga, Prachi Bajpai, Hemant K. Tiwari, Keshav K. Singh
Genome Med. 2017; 9: 31. Published online 2017 Mar 29. doi: 10.1186/s13073-017-0420-6
PMCID:
PMC5370490
AbstractArticlePDF–1.7M
7.
Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane
Hui Shi, Anthony J. Rampello, Steven E. Glynn
Nat Commun. 2016; 7: 13301. Published online 2016 Oct 27. doi: 10.1038/ncomms13301
PMCID:
PMC5095350
AbstractArticlePDF–1.5M
8.
Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity During Stress
T. Kelly Rainbolt, Justine Lebeau, Cristina Puchades, R. Luke Wiseman
Cell Rep. Author manuscript; available in PMC 2016 Mar 9.
Published in final edited form as: Cell Rep. 2016 Mar 8; 14(9): 2041–2049. Published online 2016 Feb 25. doi: 10.1016/j.celrep.2016.02.011
PMCID:
PMC4785047
AbstractArticlePDF–1.2M
9.
Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex
Chen-Wei Tsai, Madison X. Rodriguez, Anna M. Van Keuren, Charles B. Phillips, Hannah M. Shushunov, Jessica E. Lee, Anastacia M. Garcia, Amrut V. Ambardekar, Joseph C. Cleveland, Jr., Julie A. Reisz, Catherine Proenza, Kathryn C. Chatfield, Ming-Feng Tsai
Mol Cell. Author manuscript; available in PMC 2023 Oct 6.
Published in final edited form as: Mol Cell. 2022 Oct 6; 82(19): 3661–3676.e8. doi: 10.1016/j.molcel.2022.09.006
PMCID:
PMC9557913
AbstractArticlePDF–1.6M
10.
Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation
Bianca Hartmann, Timothy Wai, Hao Hu, Thomas MacVicar, Luciana Musante, Björn Fischer-Zirnsak, Werner Stenzel, Ralph Gräf, Lambert van den Heuvel, Hans-Hilger Ropers, Thomas F Wienker, Christoph Hübner, Thomas Langer, Angela M Kaindl
eLife. 2016; 5: e16078. Published online 2016 Aug 6. doi: 10.7554/eLife.16078
PMCID:
PMC4991934
AbstractArticlePDF–4.8M
11.
YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation
Lukas Stiburek, Jana Cesnekova, Olga Kostkova, Daniela Fornuskova, Kamila Vinsova, Laszlo Wenchich, Josef Houstek, Jiri Zeman
Mol Biol Cell. 2012 Mar 15; 23(6): 1010–1023. doi: 10.1091/mbc.E11-08-0674
PMCID:
PMC3302729
AbstractArticlePDF–1.8M
12.
ROMO1 is a constituent of the human presequence translocase required for YME1L protease import
Frank Richter, Sven Dennerlein, Miroslav Nikolov, Daniel C. Jans, Nataliia Naumenko, Abhishek Aich, Thomas MacVicar, Andreas Linden, Stefan Jakobs, Henning Urlaub, Thomas Langer, Peter Rehling
J Cell Biol. 2019 Feb 4; 218(2): 598–614. doi: 10.1083/jcb.201806093
PMCID:
PMC6363466
AbstractArticlePDF–2.6M
13.
RITA1 drives the growth of bladder cancer cells by recruiting TRIM25 to facilitate the proteasomal degradation of RBPJ
Huancheng Tang, Xiangdong Li, Lijuan Jiang, Zefu Liu, Lei Chen, Jiawei Chen, Minhua Deng, Fangjian Zhou, Xianchong Zheng, Zhuowei Liu
Cancer Sci. 2022 Sep; 113(9): 3071–3084. Published online 2022 Jun 28. doi: 10.1111/cas.15459
PMCID:
PMC9459252
AbstractArticlePDF–19M
14.
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence
Romina Burla, Mariateresa Carcuro, Mattia La Torre, Federica Fratini, Marco Crescenzi, Maria Rosaria D'Apice, Paola Spitalieri, Grazia Daniela Raffa, Letizia Astrologo, Giovanna Lattanzi, Enrico Cundari, Domenico Raimondo, Annamaria Biroccio, Maurizio Gatti, Isabella Saggio
Open Biol. 2016 Aug; 6(8): 160103. Published online 2016 Aug 10. doi: 10.1098/rsob.160103
Correction in:
Open Biol. 2024 Nov; 14(11): 240314.
PMCID:
PMC5008010
AbstractArticlePDF–1.4M
15.
The Shieldin complex mediates 53BP1-dependent DNA repair
Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J. Pettitt, Alexanda K. Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann, Stefano Annunziato, Dragomir B. Krastev, Feifei Song, Inger Brandsma, Jessica Frankum, Rachel Brough, Alana Sherker, Sébastien Landry, Rachel K. Szilard, Meagan M. Munro, Andrea McEwan, Théo Goullet de Rugy, Zhen-Yuan Lin, Traver Hart, Jason Moffat, Anne-Claude Gingras, Alberto Martin, Haico van Attikum, Jos Jonkers, Christopher J. Lord, Sven Rottenberg, Daniel Durocher
Nature. Author manuscript; available in PMC 2019 Jan 18.
Published in final edited form as: Nature. 2018 Aug; 560(7716): 117–121. Published online 2018 Jul 18. doi: 10.1038/s41586-018-0340-7
PMCID:
PMC6141009
AbstractArticlePDF–5.1M
16.
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies
Mansour Haidar, Bob Asselbergh, Elias Adriaenssens, Vicky De Winter, Jean-Pierre Timmermans, Michaela Auer-Grumbach, Manisha Juneja, Vincent Timmerman
Autophagy. 2019; 15(6): 1051–1068. Published online 2019 Jan 31. doi: 10.1080/15548627.2019.1569930
PMCID:
PMC6526868
AbstractArticlePDF–4.0M
17.
CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI
Wen-Feng Hu, Kimiko L. Krieger, Dragana Lagundžin, Xueli Li, Ronald S. Cheung, Toshiyasu Taniguchi, Keith R. Johnson, Tadayoshi Bessho, Alvaro N. A. Monteiro, Nicholas T. Woods
Cell Death Discov. 2019; 5: 105. Published online 2019 Jun 19. doi: 10.1038/s41420-019-0185-3
PMCID:
PMC6584691
AbstractArticlePDF–1.6M
18.
TIMMDC1/C3orf1 Functions as a Membrane-Embedded Mitochondrial Complex I Assembly Factor through Association with the MCIA Complex
Virginia Guarani, Joao Paulo, Bo Zhai, Edward L. Huttlin, Steven P. Gygi, J. Wade Harper
Mol Cell Biol. 2014 Mar; 34(5): 847–861. doi: 10.1128/MCB.01551-13
PMCID:
PMC4023825
AbstractArticlePDF–5.5M
19.
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O’Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M. Corsello, Steven A. Carr, Namrata D. Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis
Nat Commun. 2022; 13: 3181. Published online 2022 Jun 8. doi: 10.1038/s41467-022-30794-7
PMCID:
PMC9177965
AbstractArticlePDF–2.2M
20.
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat
Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54
PMCID:
PMC3817404
AbstractArticlePDF–13M

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