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Select item 99624621.

TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer’s Disease

Yi-Chun Chen, Shih-Cheng Chang, Yun-Shien Lee, Wei-Min Ho, Yu-Hua Huang, Yah-Yuan Wu, Yi-Chuan Chu, Kuan-Hsuan Wu, Li-Shan Wei, Hung-Li Wang, Ching-Chi Chiu

Int J Mol Sci. 2023 Feb; 24(4): 4085. Published online 2023 Feb 17. doi: 10.3390/ijms24044085

PMCID:: PMC9962462

Abstract Article PDF–1.7M

Select item 93753142.

TOMM40 genetic variants associated with healthy aging and longevity: a systematic review

Sunny Chen, Sara M. Sarasua, Nicole J. Davis, Jane M. DeLuca, Luigi Boccuto, Stephen M. Thielke, Chang-En Yu

BMC Geriatr. 2022; 22: 667. Published online 2022 Aug 13. doi: 10.1186/s12877-022-03337-4

PMCID:: PMC9375314

Abstract Article PDF–1.0M

Select item 86940463.

APOE, TOMM40, and Sex Interactions on Neural Network Connectivity

Tianqi Li, Colleen Pappas, Scott T. Le, Qian Wang, Brandon S. Klinedinst, Brittany Larsen, Amy Pollpeter, Ling Yi Lee, Mike W. Lutz, William K. Gottschalk, Russell H. Swerdlow, Kwangsik Nho, Auriel A. Willette

Neurobiol Aging. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Neurobiol Aging. 2022 Jan; 109: 158–165. Published online 2021 Sep 30. doi: 10.1016/j.neurobiolaging.2021.09.020

PMCID:: PMC8694046

Abstract Article PDF–797K

Select item 82265364.

TOMM40 RNA Transcription in Alzheimer’s Disease Brain and Its Implication in Mitochondrial Dysfunction

Eun-Gyung Lee, Sunny Chen, Lesley Leong, Jessica Tulloch, Chang-En Yu

Genes (Basel) 2021 Jun; 12(6): 871. Published online 2021 Jun 6. doi: 10.3390/genes12060871

PMCID:: PMC8226536

Abstract Article PDF–1.6M

Select item 80463515.

Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer’s dementia

Shizhen Tang, Aron S. Buchman, Philip L. De Jager, David A. Bennett, Michael P. Epstein, Jingjing Yang

PLoS Genet. 2021 Apr; 17(4): e1009482. Published online 2021 Apr 2. doi: 10.1371/journal.pgen.1009482

PMCID:: PMC8046351

Abstract Article PDF–1.6M

Select item 72069896.

TOMM40 ‘523 associations with baseline and longitudinal cognition in APOEε3 homozygotes

Amber Watts, Heather M. Wilkins, Elias Michaelis, Russell H. Swerdlow

J Alzheimers Dis. Author manuscript; available in PMC 2020 May 8.

Published in final edited form as: J Alzheimers Dis. 2019; 70(4): 1059–1068. doi: 10.3233/JAD-190293

PMCID:: PMC7206989

Abstract Article PDF–599K

Select item 69143947.

Genome-wide association study of hippocampal atrophy rate in non-demented elders

Yu Guo, Wei Xu, Jie-Qiong Li, Ya-Nan Ou, Xue-Ning Shen, Yu-Yuan Huang, Qiang Dong, Lan Tan, Jin-Tai Yu

Aging (Albany NY) 2019 Nov 30; 11(22): 10468–10484. Published online 2019 Nov 23. doi: 10.18632/aging.102470

PMCID:: PMC6914394

Abstract Article PDF–4.2M

Select item 58103618.

Family history and TOMM40 ‘523 interactive associations with memory in middle-aged and AD cohorts

Auriel A. Willette, Joseph Webb, Michael W. Lutz, Barbara B. Bendlin, Alexandra M Wennberg, Jennifer M. Oh, Allen Roses, Rebecca L. Koscik, Bruce P. Hermann, N. Maritza Dowling, Sanjay Asthana, Sterling C. Johnson

Alzheimers Dement. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Alzheimers Dement. 2017 Nov; 13(11): 1217–1225. Published online 2017 May 23. doi: 10.1016/j.jalz.2017.03.009

PMCID:: PMC5810361

Abstract Article PDF–708K

Select item 57534199.

The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes

Lior Greenbaum, Ramit Ravona Springer, Michael W. Lutz, Anthony Heymann, Irit Lubitz, Itzik Cooper, Efrat Kravitz, Mary Sano, Allen D. Roses, Jeremy M. Silverman, Ann M. Saunders, Michal Schnaider Beeri

Eur Neuropsychopharmacol. Author manuscript; available in PMC 2018 Jan 4.

Published in final edited form as: Eur Neuropsychopharmacol. 2014 Sep; 24(9): 1492–1499. Published online 2014 Jun 13. doi: 10.1016/j.euroneuro.2014.06.002

PMCID:: PMC5753419

Abstract Article PDF–332K

Select item 572354010.

Neuropathologic features of TOMM40 ‘523 variant on late life cognitive decline

Lei Yu, Michael W. Lutz, Jose M. Farfel, Robert S. Wilson, Daniel K. Burns, Ann M. Saunders, Philip L. De Jager, Lisa L. Barnes, Julie A. Schneider, David A. Bennett

Alzheimers Dement. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Alzheimers Dement. 2017 Dec; 13(12): 1380–1388. Published online 2017 Jun 15. doi: 10.1016/j.jalz.2017.05.002

PMCID:: PMC5723540

Abstract Article PDF–837K

Select item 565989711.

The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer’s disease

Kahli Zeitlow, Lefko Charlambous, Isaac Ng, Sonal Gagrani, Mirta Mihovilovic, Shuhong Luo, Daniel L. Rock, Ann Saunders, Allen D Roses, W. Kirby Gottschalk

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Nov; 1863(11): 2973–2986. Published online 2017 Jul 30. doi: 10.1016/j.bbadis.2017.07.031

Correction in:: Biochim Biophys Acta. 2018 Jan 27

PMCID:: PMC5659897

Article PDF–1.4M

Select item 549677812.

Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOEε4 variant

Alison C. Burggren, Zanjbeel Mahmood, Theresa M. Harrison, Prabha Siddarth, Karen Miller, Gary Small, David A. Merrill, Susan Bookheimer

Alzheimers Dement. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Alzheimers Dement. 2017 Jul; 13(7): 739–748. Published online 2017 Feb 7. doi: 10.1016/j.jalz.2016.12.009

PMCID:: PMC5496778

Article PDF–898K

Select item 402314813.

TOMM40 rs2075650 May Represent a New Candidate Gene for Vulnerability to Major Depressive Disorder

Martyn McFarquhar, Rebecca Elliott, Shane McKie, Emma Thomas, Darragh Downey, Krisztina Mekli, Zoltan G Toth, Ian M Anderson, JF William Deakin, Gabriella Juhasz

Neuropsychopharmacology. 2014 Jun; 39(7): 1743–1753. Prepublished online 2014 Jan 29. Published online 2014 Feb 19. doi: 10.1038/npp.2014.22

PMCID:: PMC4023148

Abstract Article PDF–519K

Select item 378645114.

TOMM40 rs2075650 polymorphism shows no association with neovascular age-related macular degeneration or polypoidal choroidal vasculopathy in a Chinese population

Jing Guo, Haiping Li, Chunfang Zhang, Yaoyao Sun, Xun Deng, YuJing Bai, Shanshan Li, Min Zhao, Heng Miao, Wenzhen Yu, Bin Wang, Lvzhen Huang, Xiaoxin Li

Mol Vis. 2013; 19: 2050–2057. Published online 2013 Sep 27.

PMCID:: PMC3786451

Abstract Article PDF–406K

Select item 378229615.

Improving the Resistance of a Eukaryotic β-Barrel Protein to Thermal and Chemical Perturbation

Dennis Gessmann, Frauke Mager, Hammad Naveed, Thomas Arnold, Sara Weirich, Dirk Linke, Jie Liang, Stephan Nussberger

J Mol Biol. Author manuscript; available in PMC 2013 Sep 24.

Published in final edited form as: J Mol Biol. 2011 Oct 14; 413(1): 150–161. Published online 2011 Jul 29. doi: 10.1016/j.jmb.2011.07.054

PMCID:: PMC3782296

Abstract Article PDF–1.3M

Select item 373942616.

Chronic Family Stress Moderates the Association between a TOMM40 Variant and Triglyceride Levels in Two Independent Caucasian Samples

Rong Jiang, Beverly H. Brummett, Elizabeth R. Hauser, Michael A. Babyak, Ilene C. Siegler, Abanish Singh, Arne Astrup, Oluf Pedersen, Torben Hansen, Claus Holst, Thorkild I.A. Sørensen, Redford B. Williams

Biol Psychol. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Biol Psychol. 2013 Apr; 93(1): 184–189. Published online 2013 Feb 19. doi: 10.1016/j.biopsycho.2013.02.006

PMCID:: PMC3739426

Abstract Article PDF–113K

Select item 343834617.

A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging

Kathleen M. Hayden, Jill M. McEvoy, Colton Linnertz, Deborah Attix, Maragatha Kuchibhatla, Ann M. Saunders, Michael W. Lutz, Kathleen A. Welsh-Bohmer, Allen D. Roses, Ornit Chiba-Falek

Alzheimers Dement. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Alzheimers Dement. 2012 Sep; 8(5): 381–388. Published online 2012 Aug 3. doi: 10.1016/j.jalz.2011.10.005

PMCID:: PMC3438346

Abstract Article PDF–384K

Select item 328104918.

Characterization of the Poly-T Variant in the TOMM40 Gene in Diverse Populations

Colton Linnertz, Ann M. Saunders, Michael W. Lutz, Donna M. Crenshaw, Iris Grossman, Daniel K. Burns, Keith E. Whitfield, Michael A. Hauser, Jeanette J. McCarthy, Megan Ulmer, Rand Allingham, Kathleen A. Welsh-Bohmer, Allen D. Roses, Ornit Chiba-Falek

PLoS One. 2012; 7(2): e30994. Published online 2012 Feb 16. doi: 10.1371/journal.pone.0030994

PMCID:: PMC3281049

Abstract Article PDF–89K

Select item 319230419.

TOMM40 poly-T repeat lengths, age of onset and psychosis risk in Alzheimer disease

Su Hee Chu, Kathryn Roeder, Robert E. Ferrell, Bernie Devlin, Mary Ann A. DeMichele-Sweet, M.Ilyas Kamboh, Oscar L. Lopez, Robert A. Sweet

Neurobiol Aging. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Neurobiol Aging. 2011 Dec; 32(12): 2328.e1–2328.e9. Published online 2011 Aug 5. doi: 10.1016/j.neurobiolaging.2011.06.016

PMCID:: PMC3192304

Abstract Article PDF–737K

Select item 314337520.

The Effect of TOMM40 Poly-T length on Gray Matter Volume and Cognition in Middle-Aged Persons with APOE ε3/ε3 Genotype

Sterling C Johnson, Asenath La Rue, Bruce P Hermann, Guofan Xu, Rebecca L Koscik, Erin M Jonaitis, Barbara B Bendlin, Kirk J. Hogan, Allen D Roses, Ann M Saunders, Michael W Lutz, Sanjay Asthana, Robert C Green, Mark A Sager

Alzheimers Dement. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Alzheimers Dement. 2011 Jul; 7(4): 456–465. doi: 10.1016/j.jalz.2010.11.012