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Select item 107988901.

PSMD14 stabilizes estrogen signaling and facilitates breast cancer progression via deubiquitinating ERα

Penghe Yang, Xiao Yang, Dehai Wang, Huijie Yang, Zhongbo Li, Chenmiao Zhang, Shuqing Zhang, Jian Zhu, Xin Li, Peng Su, Ting Zhuang

Oncogene. 2024; 43(4): 248–264. Published online 2023 Nov 29. doi: 10.1038/s41388-023-02905-1

PMCID:: PMC10798890

Abstract Article PDF–7.9M

Select item 101300022.

The prognostic role of PSMD14 in head and neck squamous cell carcinoma

Julia Schnoell, Alexandra Scheiflinger, Sega Al-Gboore, Lorenz Kadletz-Wanke, Lukas Kenner, Gregor Heiduschka, Bernhard J. Jank

J Cancer Res Clin Oncol. 2023; 149(6): 2483–2490. Published online 2022 Jun 25. doi: 10.1007/s00432-022-04072-4

PMCID:: PMC10130002

Abstract Article PDF–1.3M

Select item 93276633.

Identification of PSMD14 as a potential novel prognosis biomarker and therapeutic target for osteosarcoma

Yubao Gong, Zheng‐Ren Wei

Cancer Rep (Hoboken) 2022 Jul; 5(7): e1522. Published online 2021 Aug 12. doi: 10.1002/cnr2.1522

PMCID:: PMC9327663

Abstract Article PDF–9.7M

Select item 89106354.

PSMD14 Targeting Triggers Paraptosis in Breast Cancer Cells by Inducing Proteasome Inhibition and Ca²⁺ Imbalance

Hong-Jae Lee, Dong-Min Lee, Min-Ji Seo, Ho-Chul Kang, Seok-Kyu Kwon, Kyeong-Sook Choi

Int J Mol Sci. 2022 Mar; 23(5): 2648. Published online 2022 Feb 28. doi: 10.3390/ijms23052648

PMCID:: PMC8910635

Abstract Article PDF–3.0M

Select item 76446255.

Targeting PSMD14 inhibits melanoma growth through SMAD3 stabilization

Satoru Yokoyama, Yusuke Iwakami, Zhao Hang, Ryoei Kin, Yue Zhou, Yutaka Yasuta, Atsushi Takahashi, Yoshihiro Hayakawa, Hiroaki Sakurai

Sci Rep. 2020; 10: 19214. Published online 2020 Nov 5. doi: 10.1038/s41598-020-76373-y

PMCID:: PMC7644625

Abstract Article PDF–1.8M

Select item 71408976.

The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport

Hianara A Bustamante, Karina Cereceda, Alexis E González, Guillermo E Valenzuela, Yorka Cheuquemilla, Sergio Hernández, Eloisa Arias-Muñoz, Cristóbal Cerda-Troncoso, Susanne Bandau, Andrea Soza, Gudrun Kausel, Bredford Kerr, Gonzalo A Mardones, Jorge Cancino, Ronald T Hay, Alejandro Rojas-Fernandez, Patricia V Burgos

Cells. 2020 Mar; 9(3): 777. Published online 2020 Mar 23. doi: 10.3390/cells9030777

PMCID:: PMC7140897

Abstract Article PDF–8.6M

Select item 106884477.

Regulation of Drp1 and enhancement of mitochondrial fission by the deubiquitinating enzyme PSMD14 facilitates the proliferation of bladder cancer cells

Wei Song, Zhuo Li, Ming Xia, Wei Xiao

Oncol Rep. 2024 Jan; 51(1): 6. Published online 2023 Nov 16. doi: 10.3892/or.2023.8665

PMCID:: PMC10688447

Abstract Article PDF–3.8M

Select item 98282708.

Depletion of PSMD14 suppresses bladder cancer proliferation by regulating GPX4

Changxin Jia, Xin Zhang, Tingting Qu, Xiuyun Wu, Yu Li, Yang Zhao, Lijiang Sun, Qing Wang

PeerJ. 2023; 11: e14654. Published online 2023 Jan 6. doi: 10.7717/peerj.14654

PMCID:: PMC9828270

Abstract Article PDF–23M

Select item 86375649.

Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM2

Tianshui Sun, Zhuonan Liu, Fangfang Bi, Qing Yang

Mol Oncol. 2021 Dec; 15(12): 3639–3658. Published online 2021 Aug 25. doi: 10.1002/1878-0261.13076

PMCID:: PMC8637564

Abstract Article PDF–14M

Select item 805873210.

The PSMD14 inhibitor Thiolutin as a novel therapeutic approach for esophageal squamous cell carcinoma through facilitating SNAIL degradation

Chao Jing, Xingchen Li, Mengqian Zhou, Shengchi Zhang, Qingchuan Lai, Dandan Liu, Beibei Ye, Linqi Li, Yue Wu, Hong Li, Kai Yue, Peng Chen, Xiaofeng Yao, Yansheng Wu, Yuansheng Duan, Xudong Wang

Theranostics. 2021; 11(12): 5847–5862. Published online 2021 Apr 3. doi: 10.7150/thno.46109

PMCID:: PMC8058732

Abstract Article PDF–3.7M

Select item 764215611.

Cryo-EM reveals unanchored M1-ubiquitin chain binding at hRpn11 of the 26S proteasome

Xiang Chen, Zachary Dorris, Dan Shi, Rick K Huang, Htet Khant, Tara Fox, Natalia de Val, Dewight Williams, Ping Zhang, Kylie J Walters

Structure. Author manuscript; available in PMC 2021 Nov 3.

Published in final edited form as: Structure. 2020 Nov 3; 28(11): 1206–1217.e4. Published online 2020 Aug 11. doi: 10.1016/j.str.2020.07.011

PMCID:: PMC7642156

Abstract Article PDF–3.4M

Select item 346384412.

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

Laura R Butler, Ruth M Densham, Junying Jia, Alexander J Garvin, Helen R Stone, Vandna Shah, Daniel Weekes, Frederic Festy, James Beesley, Joanna R Morris

EMBO J. 2012 Oct 3; 31(19): 3918–3934. Published online 2012 Aug 21. doi: 10.1038/emboj.2012.232

PMCID:: PMC3463844

Abstract Article PDF–2.5M

Select item 890573513.

Ameliorating role of microRNA-378 carried by umbilical cord mesenchymal stem cells-released extracellular vesicles in mesangial proliferative glomerulonephritis

Wenbiao Chen, Feng Zhang, Xianliang Hou, Huixuan Xu, Donge Tang

Cell Commun Signal. 2022; 20: 28. Published online 2022 Mar 9. doi: 10.1186/s12964-022-00835-1

PMCID:: PMC8905735

Abstract Article PDF–11M

Select item 780646614.

Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness

Chao Jing, Yuansheng Duan, Mengqian Zhou, Kai Yue, Shanshan Zhuo, Xingchen Li, Dandan Liu, Beibei Ye, Qingchuan Lai, Linqi Li, Xiaofeng Yao, Hui Wei, Wenchao Zhang, Yansheng Wu, Xudong Wang

Theranostics. 2021; 11(6): 2655–2669. Published online 2021 Jan 1. doi: 10.7150/thno.48375