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Antibacterial activity against Yersinia pseudotuberculosis
Assay data:23 Tested
SummaryPubMed Citation
Binding affinity towards biotinylated His6-tagged Yersinia pseudotuberculosis CsrA measured by Microscale thermophoresis assay (MST)
Assay data:1 Tested
Inhibition of 5'-UUCACGGAGAA[flc] mRNA binding to biotinylated His6-tagged Yersinia pseudotuberculosis CsrA measured in presence of 5 mM DTT by fluorescence polarization assay
Inhibition of 5'-UUCACGGAGAA[flc] mRNA binding to biotinylated His6-tagged Yersinia pseudotuberculosis CsrA measured by fluorescence polarization assay
Assay data:1 Active, 18 Tested
SummaryCompounds, ActivePubMed Citation
Antibacterial activity against Yersinia pseudotuberculosis ATCC 6904 assessed as bacterial growth inhibition incubated for 18 to 20 hrs by broth microdilution method
Assay data:1 Active, 3 Tested
Antimicrobial activity against Yersinia pseudotuberculosis ATCC 911 incubated for 18 to 24 hrs by microbroth dilution method
Assay data:9 Tested
Inhibition of Yersinia pseudotuberculosis serotype 3 T3SS assessed as reduction in YopH protein secretion using p-nitro phenyl phosphat/2-(N-morpholino)ethanesulfonic acid as substrate preincubated for 1 hr at 26 degC and subsequently incubated for 2 hrs at 37 degC followed by addition of substrate and measured after 15 mins
Inhibition of Yersinia pseudotuberculosis serotype 3 T3SS assessed as reduction in YopD protein expression at > 13 uM preincubated for 1 hr at 26 degC and subsequently incubated for 3 hrs at 37 degC by Western blot analysis relative to control
Inhibition of Yersinia pseudotuberculosis serotype 3 T3SS assessed as reduction in YopD protein secretion at > 13 uM preincubated for 1 hr at 26 degC and subsequently incubated for 3 hrs at 37 degC by Western blot analysis relative to control
Assay data:14 Tested
Inhibition of Yersinia pseudotuberculosis Type 3 secretion system protein by SDS-PAGE analysis
Assay data:2 Tested
Antibacterial activity against Yersinia pseudotuberculosis P61 after 20 hrs by broth microdilution assay
Assay data:1 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of type 3 secretion system protein secretion in Yersinia pseudotuberculosis at 30 ug/ml incubated for 2 hrs by SDS-PAGE and densitometric analysis
Potency index, ratio of ampicillin MIC to compound MIC for antibacterial activity against Yersinia pseudotuberculosis ATCC 911
Antibacterial activity against Yersinia pseudotuberculosis ATCC 911 after 18 to 24 hrs by double microdilution method
Assay data:11 Tested
Inhibition of wild-type Yersinia pseudotuberculosis T3SS-mediated YopE secretion at 71 uM after 2 hrs under low calcium medium by SDS-PAGE analysis relative to control
Toxicity against Yersinia pseudotuberculosis harboring pYV deletion mutant at 50 ug/ml measured after 8 hrs by MTT assay
Growth inhibition of Yersinia pseudotuberculosis harboring pYV deletion mutant at 50 ug/ml measured at 30 mins interval for 8 hrs
Toxicity against wild-type Yersinia pseudotuberculosis at 50 ug/ml measured after 15 hrs by MTT assay
Growth inhibition of wild-type Yersinia pseudotuberculosis at 50 ug/ml measured at 1 hr interval for 15 hrs
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