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Inhibition of Clostridium neuraminidase preincubated for 2 mins followed by neuraminidase fluorescent addition and measured after 30 mins by fluorescence assay
Assay data:3 Tested
SummaryPubMed Citation
Inhibition of clostridium neuraminidase using fluorescent substrate preincubated for 2 mins followed by substrate addition and measured after 30 mins by fluorescence based microplate reader analysis
Assay data:9 Active, 1 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Clostridium welchii histidine decarboxylase assessed as 14CO2 production using L-histidine as substrate at 5 mM after 20 mins by scintillation counting analysis
Assay data:2 Tested
Antibacterial activity against Clostridium hypermegas by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam
Assay data:1 Tested
Antibacterial activity against Clostridium hypermegas by CLSI M11-A6 agar dilution method
Assay data:6 Tested
Antimicrobial activity against Clostridium in three-stage chemostat gut model assessed as log reduction in bacterial count at 63 mg/liter administered daily for 7 days
Antimicrobial activity against Clostridium in three-stage chemostat gut model assessed as log reduction in bacterial count at 43 mg/liter administered daily for 7 days
Antimicrobial activity against Clostridium in three-stage chemostat gut model assessed as log reduction in bacterial count at 139 mg/liter administered every 12 hrs for 7 days
Antibacterial activity against Clostridium in healthy human intestine assessed as decrease in bacterial count at 600 mg/kg, iv administered every 12 hrs for 7 days measured on day 7
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