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Development of the First Potent, Selective and CNS penetrant M5 Negative Allosteric Modulator (NAM)
Assay data:1 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Discovery of Novel Negative Allosteric Modulators of Muscarinic Receptor M5: Counterscreen against human M4
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Discovery of Novel Negative Allosteric Modulators of Muscarinic Receptor M5: Counterscreen against RAT M5
Assay data:5 Active, 1 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Discovery of Negative Allosteric Modulators of Muscarinic Receptor M5: Counterscreen against human M3
Discovery of Novel Negative Allosteric Modulators of Muscarinic Receptor M5: Counterscreen against human M2
Discovery of Novel Negative Allosteric Modulators of Muscarinic Receptor M5: Counterscreen against human M1
Discovery of Novel Negative Allosteric Modulators (NAM) of Muscarinic Receptor M5: CRC Assay
Assay data:32 Active, 3 Activity ≤ 1 µM, 42 Tested
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