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High-throughput screening primary assay to identify small molecule activators of human guanylyl cyclase B (GC-B) receptor activity
Assay data:399 Active, 370620 Tested
SummaryCompounds, Active
Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Assay data:281 Active, 189401 Tested
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS for Inhibitors of ATXN expression
Assay data:2593 Active, 3 Activity ≤ 1 nM, 2671 Activity ≤ 1 µM, 361713 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
High-throughput screening primary assay to identify small molecule activators of human GC-A enzyme activity
Assay data:519 Active, 370620 Tested
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2
Assay data:6069 Active, 5332 Activity ≤ 1 µM, 575118 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:41 Active, 124 Activity ≤ 1 µM, 15613 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:265 Active, 171 Activity ≤ 1 µM, 15637 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:160 Active, 22 Activity ≤ 1 µM, 15634 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:115 Active, 91 Activity ≤ 1 µM, 15634 Tested
Primary qHTS for Inhibitors of N-terminal methyltransferase 1 (NTMT1): MTaseGlo Assay
Assay data:1477 Active, 244 Activity ≤ 1 µM, 58936 Tested
NCATS Kinetic Aqueous Solubility Profiling
Assay data:1056 Active, 2532 Tested
SummaryCompounds, ActivePubMed Citation
Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mitochondria
Assay data:128 Active, 5056 Tested
A screen for small molecules that modulate mitochondrial supercomplex formation
Assay data:101 Active, 2017 Tested
Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay
Assay data:41 Active, 8 Activity ≤ 1 nM, 357 Activity ≤ 1 µM, 11292 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Stabilization of p53 in human papillomavirus-positive cells
Assay data:83 Active, 5741 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
MELAS cybrid survival enhancement under low glucose conditions
Assay data:264 Active, 4937 Tested
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay
Assay data:818 Active, 98760 Tested
Primary screen GU AMC qHTS for Zika virus inhibitors
Assay data:213 Active, 6757 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
Flow cytometry-based screen for inhibitors of chitosan production in Cryptococcus neoformans
Assay data:8 Active, 476 Tested
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