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Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:41 Active, 124 Activity ≤ 1 µM, 15613 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:265 Active, 171 Activity ≤ 1 µM, 15637 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:160 Active, 22 Activity ≤ 1 µM, 15634 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:115 Active, 91 Activity ≤ 1 µM, 15634 Tested
P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen
Assay data:1430 Active, 11 Activity ≤ 1 nM, 385 Activity ≤ 1 µM, 10968 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen
Assay data:1153 Active, 10968 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Human pregnane X receptor (PXR) activation by small molecules, qHTS assay
Assay data:229 Active, 16 Activity ≤ 1 µM, 2454 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
CYP3A4 induction through human pregnane X receptor (PXR) by small molecules, qHTS assay
Assay data:172 Active, 50 Activity ≤ 1 µM, 2454 Tested
Rat pregnane X receptor (rPXR) activation by small molecules, qHTS assay
Assay data:107 Active, 27 Activity ≤ 1 µM, 2454 Tested
Drug repurposing screens with cells derived from glioblastoma tumor samples
Assay data:1237 Active, 3 Activity ≤ 1 nM, 360 Activity ≤ 1 µM, 3733 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening
Assay data:2353 Active, 12805 Tested
SummaryCompounds, ActivePubMed Citation
qHTS assay to identify small molecule inhibitors of chordoma cells - UCH-2
Assay data:49 Active, 17 Activity ≤ 1 µM, 2815 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
qHTS assay to identify small molecule inhibitors of chordoma cells - UCH-1
Assay data:89 Active, 14 Activity ≤ 1 nM, 175 Activity ≤ 1 µM, 2815 Tested
qHTS assay to identify small molecule phospholipidosis (PLD) inducers
Assay data:37 Active, 24 Activity ≤ 1 µM, 3730 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
qHTS Assay for Identifying Gametocytocidal Compounds
Assay data:406 Active, 1 Activity ≤ 1 nM, 109 Activity ≤ 1 µM, 5439 Tested
qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary
Assay data:277 Active, 1 Activity ≤ 1 nM, 62 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary
Assay data:1063 Active, 1 Activity ≤ 1 nM, 58 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway
Assay data:78 Active, 75 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary
Assay data:477 Active, 2 Activity ≤ 1 nM, 241 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen
Assay data:467 Active, 55 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
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