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Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Assay data:281 Active, 189401 Tested
SummaryCompounds, Active
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: ARD_JJKsccE7 cell viability assay
Assay data:643 Active, 44 Activity ≤ 1 nM, 452 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
Various Assay from Article 10.1021/acs.jmedchem.1c00409: "Perspectives on SARS-CoV-2 Main Protease Inhibitors."
Assay data:473 Active, 1 Activity ≤ 1 nM, 248 Activity ≤ 1 µM, 795 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
3CLpro enzyme assay from Article 10.1101/2020.07.17.207019: "Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening."
Assay data:8 Active, 1 Activity ≤ 1 µM, 32 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay validation screen against the NCATS LOPAC Collection
Assay data:10 Active, 7 Activity ≤ 1 µM, 1248 Tested
Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
Assay data:523 Active, 206263 Tested
SummaryCompounds, ActivePubMed Citation
Drug screen in CRL1545 osteosarcoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:35 Active, 378 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Drug screen in RCMB18 medulloblastoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:10 Active, 378 Tested
Drug screen in BT084 (ICGC_MB145) medulloblastoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:9 Active, 378 Tested
Drug screen in Human astrocytes as non-malignant controls to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:23 Active, 378 Tested
Drug screen in UWB1.289_BRCA1 ovarian carcinoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:26 Active, 378 Tested
Drug screen in MDA-MB-436 breast carcinoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:4 Active, 378 Tested
Drug screen in LFS_MB_2R medulloblastoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:11 Active, 378 Tested
Drug screen in UWB1.289 ovarian carcinoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:14 Active, 378 Tested
Drug screen in HD-MB03 medulloblastoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:53 Active, 378 Tested
Drug screen in CRL2098 osteosarcoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:20 Active, 378 Tested
Drug screen in HTB85 osteosarcoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:38 Active, 378 Tested
Drug screen in LFS_MB_1R medulloblastoma cells to determine synergistic drug combinations that target childhood tumors with chromothripsis
Assay data:21 Active, 378 Tested
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