BioAssays, Inactive for PubChem Compound (Select 3347) - PubChem BioAssay - NCBI

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Select item 12594111.

CCRIS carcinogenicity studies

Source:: Chemical Carcinogenesis Research Information System (CCRIS)

Assay data:1139 Active, 1767 Tested

AID:: 1259411

Summary Compounds, Active

Select item 12594072.

CCRIS mutagenicity studies

Source:: Chemical Carcinogenesis Research Information System (CCRIS)

Assay data:4929 Active, 8266 Tested

AID:: 1259407

Summary Compounds, Active

Select item 7432923.

qHTS assay for cell viability of the p53RE-bla HCT-116 cell line

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:91 Active, 8 Activity ≤ 1 µM, 2810 Tested

AID:: 743292

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor

Select item 7432884.

qHTS assay for cell viability of HEK293 cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:105 Active, 14 Activity ≤ 1 µM, 2864 Tested

AID:: 743288

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 7206535.

qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:62 Active, 12 Activity ≤ 1 µM, 2864 Tested

AID:: 720653

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor

Select item 7206366.

qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: nuclear factor erythroid 2-related factor 2 isoform 1

Assay data:49 Active, 15 Activity ≤ 1 µM, 2864 Tested

AID:: 720636

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6518387.

qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:588 Active, 2864 Tested

AID:: 651838

Summary Compounds, Active PubMed Citation

Select item 6517788.

qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: Peroxisome proliferator-activated receptor alpha

Assay data:33 Active, 1 Activity ≤ 1 µM, 2864 Tested

AID:: 651778

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 6517779.

qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: aryl hydrocarbon receptor

Assay data:98 Active, 5 Activity ≤ 1 µM, 2864 Tested

AID:: 651777

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 65174310.

qHTS assay for small molecule activators of the p53 signaling pathway

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: Cellular tumor antigen p53

Assay data:88 Active, 31 Activity ≤ 1 µM, 2864 Tested

AID:: 651743

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 58854511.

qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: thyroid hormone receptor beta isoform a

Assay data:10 Active, 3 Activity ≤ 1 nM, 109 Activity ≤ 1 µM, 2858 Tested

AID:: 588545

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58854312.

qHTS assay for small molecule agonists of vitamin D receptor signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: vitamin D (1,25- dihydroxyvitamin D3) receptor

Assay data:3 Active, 7 Activity ≤ 1 nM, 72 Activity ≤ 1 µM, 2858 Tested

AID:: 588543

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58853713.

qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: peroxisome proliferator activated receptor gamma

Assay data:46 Active, 12 Activity ≤ 1 µM, 2858 Tested

AID:: 588537

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58853614.

qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: peroxisome proliferator activated receptor gamma

Assay data:3 Active, 1 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 2858 Tested

AID:: 588536

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58853515.

qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: peroxisome proliferator-activated receptor delta

Assay data:13 Active, 3 Activity ≤ 1 nM, 46 Activity ≤ 1 µM, 2858 Tested

AID:: 588535

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58853416.

qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: peroxisome proliferator-activated receptor delta

Assay data:2 Active, 1 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 2858 Tested

AID:: 588534

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58853317.

qHTS assay for small molecule antagonists of glucocorticoid receptor signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: glucocorticoid receptor [Homo sapiens]

Assay data:66 Active, 1 Activity ≤ 1 nM, 23 Activity ≤ 1 µM, 2858 Tested

AID:: 588533

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58853218.

qHTS assay for small molecule agonists of glucocorticoid receptor signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: glucocorticoid receptor [Homo sapiens]

Assay data:8 Active, 12 Activity ≤ 1 nM, 182 Activity ≤ 1 µM, 2858 Tested

AID:: 588532

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58852719.

qHTS assay for small molecule agonists of farnesoid X receptor signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: farnesoid X nuclear receptor

Assay data:3 Active, 20 Activity ≤ 1 nM, 108 Activity ≤ 1 µM, 2858 Tested

AID:: 588527

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 58852620.

qHTS assay for small molecule antagonists of farnesoid X receptor signaling

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: farnesoid X nuclear receptor

Assay data:48 Active, 3 Activity ≤ 1 nM, 23 Activity ≤ 1 µM, 2858 Tested

AID:: 588526

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (18)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (30)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (12)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (21)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (21)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

NIH MLP (3)
BioAssays deposited by the NIH Molecular Libraries Program
Other (22)
BioAssays deposited by other experimentalists

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BioAssays, Inactive for PubChem Compound (Select 3347) (30)
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